96results about How to "Reduce dissolution rate" patented technology

The invention relates to a phosphate cement based patching material and a preparation method thereof. The patching material is prepared from the following ingredients in parts by weight: 100 parts of magnesium phosphate cement, 20 to 40 parts of mineral admixtures, 120 to 140 parts of fine aggregates, 0.5 to 1 part of water glass, 0.5 to 1 part of fiber and 20 to 30 parts of water. The preparation method is characterized in that the raw materials are proportionally weighed; magnesium oxide, monopotassium phosphate and composite retarders are firstly stirred and mixed; then, the magnesium phosphate cement is obtained; then, the mineral admixtures and the fine aggregates are added; after uniform stirring, the water glass, the fiber and the water are added; stirring is performed for 3 to 4 minutes by a stirring machine; the phosphate cement based patching material is obtained. The prepared phosphate cement based patching material by the invention has the advantages that the coagulation time is about 30 minutes; the restoration time is short; the construction is not influenced; the restoration effect is obvious; the application requirement of fast patching the damaged road surface is met; the phosphate cement based patching material is applicable to fast restoration projects of cement concrete pavements.

A negative pattern is formed by coating a resist composition comprising a polymer comprising recurring units of formulae (1) and (2) and a photoacid generator of formula (3) onto a substrate, baking, exposure, PEB and developing in an organic solvent. In formulae (1) and (2), R¹ is H, F, CH₃ or CF₃, Z is a single bond, phenylene, naphthylene, or (backbone)-C(═O)—O—Z′—, Z′ is alkylene, phenylene or naphthylene, XA is an acid labile group, YL is H or a polar group. In formula (3), R² and R³ are a monovalent hydrocarbon group, R⁴ is a divalent hydrocarbon group, or R² and R³, or R² and R⁴ may form a ring with the sulfur, L is a single bond or a divalent hydrocarbon group, Xa and Xb are H, F or CF₃, and k is an integer of 1 to 4.

The invention discloses a method for preparing a magnesium alloy with a micro-arc oxidation ceramic membrane, mainly solving the problem that in the prior art, the membrane is single in variety, and the conventional membrane layers are generally red, black, green and the like in color. According to the method, an alkali electrolyte is prepared by taking sodium metaaluminate, sodium hydroxide, ethylenediamine tetraacetic acid, potassium permanganate and hydrogen peroxide as electrolyte solutes, and using diionized water as a solvent, and the alkali electrolyte is subjected to micro-arc oxidation treatment so as to obtain the magnesium alloy with a yellow micro-arc oxidation ceramic membrane. The method disclosed by the invention is simple in preparation, low in cost, wide in application range and applicable to light metal. The prepared yellow ceramic membrane has the advantages of uniform color, smooth surface, good compactness, high wearing resistance, good corrosion resistance, good stability and the like, and is particularly applicable to danger warning and reminding on yellow labels on traffic signs.

The invention discloses a solid toilet cleanser. The solid toilet cleanser is prepared from the following components, by mass, 30-40% of anhydrous sodium sulphate, 3-5% of microcrystalline cellulose, 3-5% of hydroxyethyl cellulose, 15-20% of sodium bicarbonate, 12-15% of sodium dodecyl benzene sulfonate, 5-10% of liquid 6501, 3-7% of sodium stearate, 5-8% of dodecylbenzene sulfonic acid, 3-7% of AES and 3-5% of a surfactant TX-10, and the sum of the mass percentage contents of all the components is 100%. The solid toilet cleanser has the advantages of good scale inhibiting and toilet cleaning effects, small dissolving rate in water, long service time, constant and uniform release speed of effective components in the solid toilet cleanser, and long time maintenance of the toilet cleaning effect. The invention also discloses a preparation method of the solid toilet cleanser. The method comprises the steps of weighing materials, mixing, and molding. The preparation method has the advantages of simple technologic steps and low cost.

The invention discloses an aluminum alloy electric heater anode oxide film and a preparation method thereof and belongs to the technical field of preparation of film materials. The preparation methoddisclosed by the invention comprises the following steps: adding multiple acids such as sulfosalicylic acid, boric acid, oxalic acid, sulfuric acid, aluminum sulfate octadecahydrate and the like intoelectrolyte, performing mixed acid anodic oxidation treatment at the temperature of 3-10 DEG C for 40 minutes under the mechanical stirring condition, wherein the current density is 1.5-2.5A/dm<2>. The preparation method disclosed by the invention is simple and feasible in process, and the prepared anode oxide film has high corrosion resistance.

The invention discloses a compound crystal, and a preparation method and application thereof, belonging to the technical field of chemical medicines. The compound crystal is a eutectic crystal of favipiravir and p-aminobenzoic acid, the unit cell of the eutectic crystal belongs to a monoclinic system and a P21/c space group, and the unit cell parameters are as follows: alpha = gamma = 90 degrees and beta = 92.578 (3) degrees. The equivalent solubility of the favipiravir in the compound crystal provided by the invention is reduced by about 50%, so that the dissolution rate of the favipiravir is favorably reduced, the onset time of the favipiravir is prolonged, and the toxic and side effects of the favipiravir are reduced.

The invention provides a prasugrel eutectic with a structure shown in the specification, and a preparation method, a medicinal composition and application thereof. The prasugrel eutectic does not contain a solvent and is low in hygroscopicity, so that the preparation and storage of Chinese herbal medicines are facilitated. Experiments for testing dissolubility prove that the prasugrel eutectic is relatively low in dissolution speed, so the prasugrel eutectic can be used as a sustained-release agent for prasugrel medicines to overcome the defect of increasing hemorrhagic risks. In addition, the method for preparing the prasugrel eutectic is simple, and easy to operate.

The invention discloses oviductus ranae microcapsules and a preparation method thereof, and belongs to the technical field of processing of functional oil and fat products. The microcapsules are prepared with sodium alginate and chitosan serving as wall materials and oviductus ranae serving as a core material. The microcapsules are prepared from, by mass, 1-3% of sodium alginate, 1-3% of chitosan, 1.5-8% of oviductus ranae, 2-6% of anhydrous calcium chloride, 0.5-1% of tween-80, 1% of acetic acid and the balance water. The preparation method of the microcapsules includes the main steps that 1, a wall material solution and an immobilization solution are prepared; 2, oviductus ranae and a sodium alginate solution are mixed according a certain proportion; 3, emulsification homogenization treatment is carried out; 4, the microcapsules are prepared through a piercing-solidifying method. According to the microcapsules and the preparation method thereof, bioactive substances of oviductus ranae are maintained, and many defects of oviductus ranae are overcome. The microcapsules are convenient to preserve, and the fishy smell of oviductus ranae is removed. The preparation method is easy to implement and beneficial for industrial production and opens up a new field for deep processing of rana temporaria.

Provided are pharmaceutical compositions and methods for preparing pharmaceutical compositions comprising Ibuprofen using solventless mixing methods. Excess coating material that is not bound to coated Ibuprofen may be removed by a sieving process. Coating and dosing ratios can also be optimized to minimize the amount of excess unbound coating material. Additionally, the compositions can be formulated to preserve the functional coating of coated Ibuprofen and to minimize aeration of Ibuprofen when mixed into suspension.

The invention provides a sewage treatment agent with a slow release function. The sewage treatment agent comprises the following components in parts by weight: 30-45 parts of dephosphorization flocculant, 15-25 parts of slow release agent and 50-60 parts of solid carrier. The invention aims to provide the sewage treatment agent with the slow release function. The dephosphorization flocculant is effectively and continuously released after the sewage treatment agent reaches the middle and lower layers of sewage, a dephosphorization effect can be achieved while the continuous addition of chemicalagents can be avoided, so that an efficient and stable dephosphorization effect can be achieved.

The invention discloses biological organic fertilizer. Raw materials of the fertilizer includes modified biological carbon, sugarcane leaves, crop straw, corncobs, excrement of livestock and poultry,a fermentation bacterial inoculant, a functional microbial strain, ammonium chloride, potassium nitrate, calcium magnesium phosphate, monopotassium phosphate and compound trace elements. The inventionalso discloses a preparation method of the biological organic fertilizer. Under interaction of each added raw material, nutrients are supplied to meet the growth demands of crops; meanwhile, the utilization rate of fertilizer nutrients can also be increased, the soil structure can be improved, and healthy growth of crops is facilitated.

The invention discloses a high-dispersity edible instant thickener and a preparation method thereof. The thickener comprises the following raw materials in percentage by mass: 1-10% of a block formation inhibitor, 20-75% of xanthan gum and 20-75% of dextrin, wherein the block formation inhibitor comprises a composition containing one or more of glutamic acid, aspartic acid, glycine, erythritol andpotassium chloride. The composition is prepared from the following components in percentage by mass: 16 to 24% of glutamic acid, 16 to 24% of aspartic acid, 16 to 24% of glycine, 5 to 10% of erythritol and 25 to 40% of potassium chloride. The invention also provides a preparation method of the thickener. The prepared thickener can improve the dispersity of liquid in the thickener and inhibit theblock formation, so that xanthan gum can fully exert a thickening function, and the special taste generated by potassium chloride can also be improved.

The invention provides a new crystal form of (7S, 13R)-11-fluorine- 7, 14-dimethyl-6, 7, 13, 14-tetrahydro-1, 15-ethylene bridge pyrazolo [4, 3-f] [1, 4, 8, 10] -benzoxaza-triazacyclo-tridecyne-4 (5H)-one, and on the other hand, the invention provides a preparation method of the crystal form. Compared with the prior art, the crystal form prepared by the invention is high in stability, low in hygroscopicity, simple and convenient in preparation method, good in solubility and suitable for subsequent preparation research and development and industrial production.

The invention discloses a method for preparing a continuous gradient biological coating by utilizing suspension plasma spraying. A calcium silicate/fluorohydroxyapatite continuous gradient biologicalcoating is prepared on the surface of a titanium or titanium alloy matrix by utilizing a suspension plasma spraying method. The high bonding strength between a calcium silicate coating and the titanium matrix and the low solubility of fluorohydroxyapatite are utilized, solid phase components of a mixed solution are gradually changed by adjusting the liquid feeding rates of two suspensions, the continuous gradient coating is prepared on the surface of the titanium or titanium alloy matrix by adopting a suspension plasma spraying technology, namely, the calcium silicate is arranged at the bottomof the coating, the fluorohydroxyapatite is arranged at the top of the coating, gradient component transition is achieved between the top and the bottom, the internal stress of the coating can be greatly reduced through gradient design, and the sensitivity at an interface is reduced. The binding force between the calcium silicate/fluorohydroxyapatite gradient coating and the titanium matrix is obviously improved, the dissolution rate is obviously reduced, and the coating shows good biological activity and antibacterial activity.

The invention relates to an uncoupling agent containing 2,4,5-trichlorophenol, a soluble metal salt and an adsorbent, wherein the soluble metal salt is soluble ferric salt and / or soluble aluminum salt. The invention also relates to the application of the uncoupling agent to an activated sludge method for the treatment of wastewater. In the process of the activated sludge method for the treatment of wastewater, the uncoupling agent provided by the invention can realize high COD removal rate and sludge reduction rate, and the water outlet has small TP concentration.

The invention relates to the field of pharmaceutical materials, and discloses a piracetam eutectic, which is synthesized by using piracetam and gentilic acid, wherein the molecular formula is C6H10N2O2 C7H6O4, and the molecular weight is 296; the eutectic structure is that O atoms of phenolic hydroxyl groups adjacent to gentilic acid and carboxyl are used as hydrogen bond acceptors, and N atoms onpiracetam amino groups are used as hydrogen bond donors to form intermolecular double bonds; double bond O atoms on the gentilic acid carboxyl are used as hydrogen bond acceptors, and the O atoms onthe adjacent phenolic hydroxyl groups are used as hydrogen bond donors to form an intramolecular hydrogen bond so as to jointly form a basic unit of the eutectic; the crystal is c2/c and monoclinic, and the cell parameters are shown in the description, wherein alpha=gamma=90 degrees, beta=101.09 degrees, Z=8. Compared with the original piracetam, the dissolution rate and stability of the medicineeutectic are greatly improved.

The invention belongs to the technical field of veterinary chemical medicinal preparations, and particularly relates to a dimetridazole soluble powder and a preparation method thereof. The dimetridazole soluble powder is prepared from the following components in parts by weight: 18-22 parts of dimetridazole and 10-15 parts of hydrophilic carrier, and the balance of glucosum anhydricum or lactose anhydrous supplemented to 100 percent, wherein the hydrophilic carrier is one or more of PVP K30, poloxamer 188 and sodium lauryl sulfate. According to the dimetridazole soluble powder, the specific surface area of an insoluble medicine can be improved, and the wetting property can be increased, so that solubility of dimetridazole can be improved, the dissolving time is shortened, and the aim of clinical drinking water administration can be achieved. The dimetridazole has good bioavailability and good medicinal effect.

The invention belongs to the technical field of magnesium-lithium alloys, and particularly relates to a high-ductility soluble magnesium-lithium alloy and a preparation method and application thereof. Aiming at the problems of low ductility, incomplete dissolution and the like of a packing tool in fracturing transformation construction of an oil and gas field, the high-ductility soluble magnesium-lithium alloy is obtained through alloy component design and by adopting the processes of vacuum casting, low-temperature severe plastic deformation, heat treatment and the like, and the alloy is prepared from the following components in percentage by mass: 9.0-12.0% of Li, 0-2.5% of Al, 0.1-1.0% of Zn, 0.1-1.0% of Ni, 0.2-1.0% of Cu, less than or equal to 1.0% of RE, and the balance of Mg. The tensile strength of the prepared magnesium-lithium alloy is not lower than 120 MPa, the yield strength is not lower than 90 MPa, the ductility is not lower than 45%, and the magnesium-lithium alloy can be used for machining and preparing high-plasticity soluble downhole tools used in the oil and gas field fracturing process, such as all-metal full-bore soluble bridge plugs, sealing rings or sealing rings.