119 results about "Continuous infusion" patented technology

When using a drug container having an identification tag fixed or detachably provided at a predetermined position of the container, the tag having drug data on a kind and a concentration of a drug and both or one of upper and lower limits of a flow rate on a continuous infusion and the upper and lower limits, time and flow rate on a one-shot administration recorded thereon, it is possible to ensure safety by prompting for a stop of injection by a warning when a setting beyond the upper and lower limits is performed and rewrite a liquid infusing time and a flow rate and so on required to be set according to symptoms of a patient.

Disclosed is a medical infusion device including a dedicated processing unit for detecting abnormal operation of the operation of the device. Specifically, a watchdog controller is employed as an independent monitor of the functioning of microprocessors used in the medical infusion device for controlling things such as RF communication, insulin infusion, and system integrity. Through the use of an independently-powered watchdog control system, the accuracy and reliability of the device is enhanced, resulting in greater assurance to the patient receiving periodic or continuous infusion of a drug.

Compositions containing a carrier and microbubles encapsulating one or more gases, preferably oxygen, and methods for making and using the compositions are described herein. The microbubbles contain a lipid envelope formed of at least one base lipid and at least one emulsifying agent. The compositions may be administered to a patient to quickly deliver large amounts of oxygen to the patient's blood supply or directly to a tissue in need of oxygen. The compositions may be administered via injection or as a continuous infusion. The compositions contain a concentrated microbubble suspension, where the suspension contains at least 40 mL oxygen / dL suspension. The microbubbles are preferably less than 20 microns in diameter, more preferably less than 15 microns in diameter. The microbubbles described herein may be administered to a patient in an effective amount to increase in oxygen concentration in the patient's blood, and / or one or more tissues or organs. The microbubbles may be administered alone or in combination with other treatments as an adjuctive therapy.

The present invention provides a monomeric insulin analog formulation stabilized against aggregation in which the buffering agent is either TRIS or arginine. The stable formulations of the present invention are useful for treating diabetes, and are particularly advantageous in treatment regimes requiring lengthy chemical and physical stability, such as, in continuous infusion systems.

A micropump according to the invention uses an eccentric cam member rotating within a pump housing to sequentially open and close valves in the pump housing to withdraw fluid from a reservoir and provide metered amounts of the fluid to a cannula port for administration to a patient. The micropump may be used in a disposable pump for continuous infusion of medication such as insulin.

The present invention generally relates to radio-enabled devices for detection and remedy of biological and chemical warfare attack. More particularly, this invention relates to an on-body apparatus that provides a means of treatment which is innocuous to the wearer, but capable of injecting antidotes within seconds and preferably also combines multiple means of sensing chemical and biological agents as well as monitoring user's physiological response to the antidotes thereby to enable tailored and continuous infusion of antidotes while minimizing the side effect of the antidotes themselves. A key embodiment of this invention is the incorporation of an electronically-controlled needle or cannula that will deploy only when commanded to. When not deployed, the device sits inertly against the patient's skin, affixed by adhesive and or elastic materials.

The present invention relates to the development of a pharmacological non-human animal model that associates memory loss to histopathological features found in the brain of a subject having Alzheimer's Disease. In one embodiment, a four-week continuous infusion of a Fe2+, Aβ42 and buthionine sulfoximine (FAB) solution in the left ventricle of young adult Long-Evans rats induced memory impairment accompanied by increased hyperphosphorylated Tau protein levels in cerebrospinal fluid. Brains from treated animals displayed neuritic plaques, tangles, neuronal loss, astrogliosis and microgliosis in hippocampus and cortex. The present invention may be utilized in evaluating preventive, therapeutic and diagnostic means for neurologic diseases.

The invention relates to the field of medical instruments, in particular to a vein continuous infusion intelligent controller and an application method thereof. The technical scheme is as follows: a single machine can realize uninterrupted continuous infusion of multiple bags; according to different types of drug in each bag, the dropping speed and drug amount can be regulated; the intelligent controller can automatically rinse an infusion tube, automatically gives an alarm and closes for abnormal infusion, automatically closes after infusion is finished and notifies a central display monitor system to process. The invention changes the current situation of gravity infusion, artificial care, manual bag change and manual dropping speed control, greatly lightens the labor intensity and psychological nervousness of hospitals and patient family members, causes infusion treatment to become relaxed, safe, ordered, precise and controllable and can greatly save manpower, so that nurses have time to observe the treatment situation of patients. In addition, the invention can improve clinic drug administration efficiency, lowers treatment risk, improves vein drug administration treatment level, and improves hospital treatment level and nursing images; and furthermore, the invention has low manufacture cost and strong practicality and is favorable for popularizing and applying.

The invention relates to a continuous liquid infusion device which can be easily prepared for operation with small force, and can infuse liquid at constant infusion rate and amount over a long time. It comprises a liquid syringe section and a driving pump section mounted on the liquid syringe section, wherein sliding the pressing arm of the driving pump section upward leads to axially slides the piston in the negative pressure chamber to produce a negative pressure therein; and using returning force of the piston under the negative pressure, the liquid pushout plunger barrel is biased toward the upper edge of a pressing member through a locking member engaged with the piston so as to push out liquid in the liquid syringe from the liquid infusion port. Further, only the liquid syringe is disposable while the vacuum pump barrel on the driving side is good for repeated use (reusable).

The invention discloses an intermittent transfusion set, which comprises an air inlet tube air filter, a bottle plug puncture unit, a drip cup and an injection needle head, and is characterized in that: the drip cup has a Y-shaped three-way structure, and is provided with two branch tubes to which two transfusion paths are connected; a one-way valve is arranged in the branch tube on a left side; under the action of the one-way valve, a liquid is only allowed to flow downwards; a saline water bottle is connected to the branch tube on the left side; and a medicament bottle is connected to a branch tube on a right side. The intermittent transfusion set has the advantages: when multiple bottles of liquids are required to be transfused continuously for a patient, saline water on the left side can be transfused continually if the medicament bottle replacing time is intermittent or delay, so that the phenomena of blood return and the introduction of excessive air into a transfusion pipeline are avoided; medical personnel can nurse a plurality of patients receiving transfusion simultaneously, so that the quantity of nursing personnel can be reduced; and a secondary transfusion path can play a role in eroding a primary transfusion path after dripping of the main transfusion path, so that pharmacological reactions among different medicaments are avoided. The intermittent transfusion set can be applied to one-time transfusion for various types of patients on medical treatment.

The invention relates to a continuous liquid infusion device which can be easily prepared for operation with small force, and can infuse liquid at constant infusion rate and amount over a long time. It comprises a liquid syringe section and a driving pump section mounted on the liquid syringe section, wherein sliding the pressing arm of the driving pump section upward leads to axially slides the piston in the negative pressure chamber to produce a negative pressure therein; and using returning force of the piston under the negative pressure, the liquid pushout plunger barrel is biased toward the upper edge of a pressing member through a locking member engaged with the piston so as to push out liquid in the liquid syringe from the liquid infusion port. Further, only the liquid syringe is disposable while the vacuum pump barrel on the driving side is good for repeated use (reusable).

The invention relates to an automatic liquid replacing system. The system comprises a controller, an infusion control unit and a liquid detection unit; the controller is connected to the infusion control unit and the liquid detection unit separately, wherein the infusion control unit is detachably arranged on an infusion apparatus and used for connecting or disconnecting a puncture pipe in a random puncture module in the infusion apparatus; the liquid detection unit is detachably arranged on a pipeline above a drip bulb in the infusion apparatus and used for detecting whether or not liquid exists in the pipeline and sending signals to the controller; the controller is used for receiving the signals sent by the liquid detection unit and controlling the infusion control unit to make puncturepipes in all puncture modules in the infusion apparatus connected or disconnected. The automatic liquid replacing system has the advantages of being simple in structure, low in cost, capable of recycled and the like, and can achieve automatic liquid replacing and continuous infusion processes of the infusion apparatus.

The invention relates to a double-way unintermittent infusion set and belongs to a medical infusion set. The double-way unintermittent infusion set comprises bottle plug puncture units, an air inlet pipe air filter, a dropper and a needle which are sequentially connected through a hose, and a flow adjuster is sleeved on the hose. The double-way unintermittent infusion set is characterized in that the infusion set further comprises a tee joint, two branch tubes of the tee joint are connected with two infusion tubes, each infusion tube is provided with one bottle plug puncture unit and a one-way valve. The double-way unintermittent infusion set has the advantages that when a patient is subjected to infusion of multiple bottles of liquor medicines continuously, infusion medicine bottles can be automatically switched, unintermittent infusion is realized, burden of medical staff is alleviated, infusion efficiency is improved, and the problems of waste of liquor medicine, air entering the tubes and blood return and the like are avoided. The double-way unintermittent infusion set can be widely used for one-off infusion of various patients.

The invention provides a venous infusion apparatus, which comprises bottle plug puncture outfits for an existing venous infusion apparatus, an air filter, an observation window, a flow adjustor and a syringe needle. The venous infusion apparatus is characterized in that during continuous and automatic infusion of multiple bottles of liquid medicine, a check valve or a switch floating valve is additionally mounted on a liquid outlet port of the bottle plug puncture outfit of each bottle of liquid medicine, and a circuit switch device is additionally mounted at the rear of the switch floating valve of the last bottle of liquid medicine. A circuit connected with the circuit switch device is parallelly connected with an electromagnetic valve and an alarm. Automatic and continuous infusion of the multiple bottles of liquid medicine is realized, the multiple bottles of liquid medicine do not need to be changed manually, when infusion of the last bottle of liquid medicine is finished, an infusion pipeline is cut off automatically, simultaneously, the venous infusion apparatus makes an alarming sound, so that work intensity of nursing staffs is greatly reduced, burden of infusion patientsor accompany members thereof is also reduced, and accidents are decreased. Accordingly, the venous infusion apparatus has a high market development value.

A method for automatically adjusting PCA (patient controlled analgesia) infusion parameters of an electronic infusion pump comprises following steps: step S1, the number of generation times of PCA activation signals is acquired through a PCA assembly in a preset timing cycle; step S2, whether the times of the PCA activation signals in the preset timing cycle are smaller than or equal to a lower threshold of the times, are larger than the lower threshold of the times and smaller than an upper threshold of the times, or are larger than or equal to the upper threshold of the times is judged, a step S3 is executed when the times are smaller than or equal to the lower threshold of the times, a step S4 is executed when the times are larger than the lower threshold of the times and smaller than the upper threshold of the times, and a step S5 is executed when the times are larger than or equal to the upper threshold of the times; step S4, the continuous infusion amount keeps a current value; step S5, the current continuous infusion amount is progressively increased once according to a preset second dosage. According to the method, the continuous infusion amount can be adjusted according to PCA activation operation of a patient, so that the defect of excessive analgesia or insufficient analgesia is overcome, and the method is safer and more convenient.

The present invention relates to an ELECTRO MECHANICAL PRESSER WITH RIBBED BOTTLE FOR INFUSION OF LIQUIDS. The invention comprises a presser holder through which a mechanism connected to an electric motor presses a ribbed bottle containing liquid to be administered to a patient, thereby providing a continuous infusion of the same. The invention solves the problem of disruption of liquid infusion attributable to the creation of a vacuum in the bottle.

The invention relates to a continuous infusion device for automatically switching infusion channel sequence, comprising a puncturing device (1), an infusion switch (2), an infusion hose (3), a Maffeitube (5), a flow rate regulator (6), a pharmaceutical liquid filter (7) and an intravenous infusion needle (8), wherein the continuous infusion device further comprises a controller (4). The infusionswitch (2) is used for controlling the infusion lines of a plurality of infusion bags, the controller (4) utilizes the float slide valve as the driving force with buoyancy and gravity as the driving force, realizes the automatic switching of the multi-infusion channels through the clever mechanical structure, achieves the sequential continuous infusion of the multi-infusion bags without manual intervention, and has the automatic exhaust effect, further prevents the accidental occurrence. The infusion device is simple in structure, stable in control and low in cost, and is very suitable for popularizing and using in medical institutions such as hospitals, so as to reduce the workload of medical workers and improve efficiency.

A micropump according to the invention uses an eccentric cam member rotating within a pump housing to sequentially open and close valves in the pump housing to withdraw fluid from a reservoir and provide metered amounts of the fluid to a cannula port for administration to a patient. The micropump may be used in a disposable pump for continuous infusion of medication such as insulin.

The invention relates to an automatic infusion device and method. The automatic infusion device is characterized in that an object carrying module is connected with a driving module, and the driving module is connected with a main control module; a man-machine interaction module is connected with the main control module and used for obtaining input patient information, calling infusion informationof a corresponding patient from a background according to the patient information and displaying the infusion information; a scanning module is connected with the main control module and used for scanning drug information identifiers arranged on the surfaces of infusion containers so as to obtain drug information; a clamping module is connected with the main control module; and a detecting moduleis used for sending a detection signal to the main control module when detecting the situation that the liquid height of remaining liquid in the first infusion container is smaller than the preset liquid height, the main control module controls the clamping module to clamp an infusion tube according to the detection signal and then controls a puncture outfit of a puncture executing module to be pulled out of the first infusion container, and then an opening of the second infusion container is punctured. According to the automatic infusion device and method, a plurality of infusion bottles (orbags) can be replaced automatically during continuous infusion and do not need to be manually replaced by a nurse, and thus the working efficiency of the nurse is improved.

The present invention relates to preparations and methods for treating a GD2 positive cancer by administering a preparation comprising a chimeric or humanized anti-GD2 antibody to a patient, wherein the patient is not concomitantly treated with interleukin-2 (IL-2 wherein a GD2 positive cancer is treated in the patient. Furthermore, the invention relates to preparations and methods for the treatment of a GD2 positive cancer in a patient, wherein a preparation comprising an anti-GD2 antibody is administered to the patient as a continuous infusion, without concomitantly administering IL-2. The present invention further relates to preparations and methods for the treatment of a GD2 positive cancer in a patient, wherein the one or more anti-GD2 antibody treatment periods is / are preceded, accompanied, and / or followed by one or more treatment periods with a retinoid.

The invention relates to a self-adaption continuous infusion apparatus. The self-adaption continuous infusion apparatus comprises an upper half part and a lower half part, and is characterized in that the upper half part is provided with a bottle plug puncture device (2) and a bottle plug puncture device protection cover, the upper end of the bottle plug puncture device (2) is used for puncturing through a bottle plug of a to-be-infused bottle, and the bottle plug puncture device protection cover is fixedly arranged on the bottle plug puncture device (2) to protect the bottle plug puncture device (2). In the self-adaption continuous infusion apparatus, the situations are avoided that infusion is automatically stopped after infusion is completed, the blood return phenomenon is caused when nurses do not attend on patients timely and the liquid level drops to a too low level, more seriously, gas enters the human body, which results in bad results like aeroembolism, or when multiple infusion bottles are infused continuously, if the liquid level is lower than the lower part of a Murphy's dropper, air exhaust needs to be conducted again or intravenous injection needs to be conducted again; meanwhile, to prevent the situation that the liquid level is lower than the Murphy's dropper, the nurses, patients and relatives need to conduct nursing in real time, which results in unnecessary tension and psychological burdens of the three parties, therefore, the psychological burden in seeking medical service can be sharply lowered through automatic stopping of infusion, and thus the comfort in seeking medical service is improved.

The invention relates to a continuous infusion apparatus with the automatic air exhaust function. The continuous infusion apparatus comprises an infusion apparatus upper part (1), an infusion apparatus middle part (2) and an infusion apparatus lower part (3), wherein the infusion apparatus upper part (1), the infusion apparatus middle part (2) and the infusion apparatus lower part (3) are connected in sequence. The continuous infusion apparatus is characterized in that the infusion apparatus middle part (2) comprises a regulating drip tube (21), and the regulating drip tube (21) comprises an infusion controller (4) and a drip tube body (5). With the continuous infusion apparatus with the automatic air exhaust function, on one hand, the problem that during the infusion process adopting a plurality of infusion bottles, the infusion bottles need to be replaced manually and frequently is solved, so that abundant time and effort of medical staff are saved, on the other hand, the undesirable phenomena that the liquid medicine is wasted, the connecting hole is infected, blood returns, air enters the human body, and the like are avoided, and thus the psychological burden of patients and the medical staff is greatly alleviated.

The invention provides regimens and methods for the treatment of cancer comprising continuous infusion of coenzyme Q10. The coenzyme Q10 may be administered as a monotherapy, or in combination with an additional agent, such as an anticancer agent, a chemotherapeutic agent, or an anti-angiogenic agent. The coenzyme Q10 may be administered at two or more different rates.

The invention relates to a two-channel transfusion head of automatically controlling liquid and gas to be transfused by time phases. The two-channel transfusion head comprises an independently used transfusion head body or at least two transfusion head bodies serially connected for use. A pure gas channel and a pure liquid channel are arranged in each transfusion head body, wherein the top end of each pure gas channel is open; the bottom end of each pure gas channel is provided with a floating valve chest communicated with the bottom end of the pure gas channel; a floating valve which vertically floats is arranged in the floating valve chest; one side of each floating valve chest is communicated with a gas / liquid inlet; the top end of each pure liquid channel is also open; the bottom end of each pure liquid channel is communicated with a gas / liquid outlet; and the bottom part of each pure liquid channel is also communicated with the bottom end of the corresponding floating valve chest. According to the two-channel transfusion head of automatically controlling the liquid and the gas to be transfused by time phases, the goal that the liquid and the gas pass through the transfusion head by time phases and by channels is realized; automatic control is realized during the whole process; the goal that multiple bottles of liquid can be connected in series to be continuously transfused is achieved, and therefore, the problem that liquids are mixed when the multiple bottles of liquid are connected in series to be continuously transfused is avoided, bottle replacing operations of nurses can be reduced, and the labor strength of the nurses can be relieved.

A system and method for intravenous, intramuscular, or subcutaneous delivery of a reconstituted medication fluid with simultaneous, uninterrupted delivery of a primary fluid. A medication fluid is prepared by reconstituting a medication with a primary fluid as diluent. A container adapted to receive a medication is retro-primed with primary fluid from a primary bag. The primary fluid mixes with the medication to reconstitute the medication and form a medication fluid. A medication delivery system and method according to the present invention allows for the continuous infusion of primary fluid both during and after the administration of a reconstituted medication, using a closed system with reduced opportunities for contamination and infection.

The invention relates to a transfusion device having automatic bottle change and safety protection functions. The structure of the transfusion device is that a first transfusion bottle gas passage is communicated with a gas inlet, a second transfusion bottle gas passage is communicated with an air space above a liquid stop film in a protection chamber, the air spaces above the liquid stop films in the two protection chambers are not communicated with each other, the protection chambers are integrally sealed, the air space is formed above the liquid stop film, a baffle is fixedly connected below the liquid stop film, a liquid leaking hole is formed in the baffle, a floating block is arranged below the baffle, an outlet is formed in the middle of the bottom of the protection chamber, the outlet is communicated with a transfusion pipe, and each transfusion bottle liquid passage is communicated to the position below the liquid stop film and above the baffle in the protection chamber. According to the invention, the protection chambers are utilized to enable multiple transfusion bottles to transfuse continuously and close the transfusion pipe after transfusion is completed, so as to prevent vein blood backflow, thereby greatly improving the transfusion safety and reducing the workload of medical care personnel.

The invention provides a continuous liquid infusion device in which liquid syringe and a negative pressure cylinder are separable to use a liquid infused syringe. This continuous liquid infusion device includes: a negative pressure cylinder having a barrel part including an open / close valve at its tip and leg parts extending from a base end thereof; a piston air-tightly fitted in the barrel part and connected to a base end of an outer case covering an outer surface of the barrel part, through slots between the leg parts; a liquid syringe having a liquid infusion / discharge port at its tip, and a base end screwed with the outer case so that the liquid syringe is positioned back to back with the negative pressure cylinder; and a movable unit liquid-tightly fitted to an inner circumference of the tip of the liquid syringe and abutting against a base end of the leg parts.