2 results about "Continuous infusion" patented technology

The present invention is directed to methods for treating or preventing neuroinflammation in a subject by administering an effective amount of a single-domain antibody (sdAb) comprising SEQ ID NO:1. The method is applicable to subjects with multiple sclerosis, including secondary progressive, primary progressive, and relapsing-remitting forms. Administration may be intravenous, subcutaneous, or intrathecal, with dosage regimens including daily administration, loading and maintenance doses, or continuous infusion. The method may be initiated upon first clinical signs of central nervous system demyelination and continued for at least 14 days. The sdAb may be co-administered with a pharmaceutically acceptable excipient such as mannitol, sucrose, or polysorbate 80, and optionally combined with disease-modifying therapies including interferon-β, glatiramer acetate, fingolimod, or ocrelizumab. The invention provides a targeted approach for modulating neuroinflammatory processes in neurological disorders.

The application discloses a constant-speed infusion device and method, wherein the device comprises: an infusion module comprising an infusion bag and an infusion pipeline; a pressurizing module comprising a pressurizing air bag wrapped around the outer periphery of the infusion module, the pressurizing air bag being connected with an external high-pressure gas source through a gas inlet pipeline; a pressure regulating module comprising a first-stage pressure regulating mechanism, a second-stage pressure regulating mechanism and an automatic switching mechanism arranged on the gas inlet pipeline; and a detection module comprising a first air pressure detection mechanism for detecting the air pressure value in the pressurizing air bag in real time. The application simplifies the operation steps, realizes rapid and seamless continuous infusion, and can guarantee the stability and safety of the infusion process through real-time monitoring of the air pressure condition and rapid switching of the automatic switching mechanism.