23 results about "Implantable Pump" patented technology

Systems and methods for controlling an implantable pump are provided. For example, the exemplary controller for controlling the implantable pump may only rely on the actuator's current measurement. The controller is robust to pressure and flow changes inside the pump head, and allows fast change of pump's operation point. For example, the controller includes, a two stage, nonlinear position observer module based on a reduced order model of the electromagnetic actuator. The controller includes an algorithm that estimates the position of the moving component of the implantable pump based on the actuator's current measurement and adjusts operation of the pump accordingly. Alternatively, the controller may rely on position measurements and / or velocity estimations.

An implantable pump system is provided, including an implantable blood pump suitable for use as a partial support assist device, the system further including an extracorporeal battery and a controller coupled to the implantable pump, and a programmer selectively periodically coupled to the controller to configure and adjust operating parameters of the implantable pump. The implantable pump includes a flexible membrane coupled to an electromagnetic actuator including a magnetic assembly and electromagnetic assembly, so that when the electromagnetic assembly is energized, the electromagnetic assembly causes wavelike undulations to propagate along the flexible membrane to propel blood through the implantable pump. The controller may be programmed by a programmer to operate at frequencies and duty cycles that mimic physiologic flow rates and pulsatility while operating in an efficient manner that avoids thrombus formation, hemolysis and / or platelet activation.

A blood pump may be provided for supporting heart function. A method may be provided for producing a pump housing of the blood pump. The provided blood pump comprises an implantable pump housing. The blood pump additionally comprises a fiber optic sensor comprising an optical fiber. The optical fiber is at least partially accommodated in a housing part of the pump housing.

Systems and methods are provided for a bodily fluid management system for pumping bodily fluid such as lymph. The bodily fluid management system may include an implantable pump with a rotor having a magnetic portion and inlet and outlet tubes that connect to a fluid chamber. The fluid chamber has a volume that can be selectively reduced or increased via the rotor. The rotor is designed to periodically open and close kinking valves at each of the inlet and outlet tube to permit bodily fluid to enter the fluid chamber during an intake cycle and exit the fluid chamber during a discharge cycle. The magnetic portion of the rotor may be caused to rotate by an external controller that is positioned outside of the body and adjacent to the pump. The external controller may have a magnet that magnetically interfaces with the rotor to cause the rotor to rotate.

A system and method are provided for a body fluid management system for pumping body fluids such as lymph. The body fluid management system may include an implantable pump having: a rotor having a magnetic portion; and inlet and outlet pipes connected to a fluid chamber. The fluid chamber has a volume that can be selectively decreased or increased via the rotor. The rotor is designed to periodically open and close a bend valve at each of the inlet and outlet pipes to allow body fluid to enter the fluid chamber during an inhalation cycle and exit the fluid chamber during an exhalation cycle. The magnetic portion of the rotor can be rotated by an external controller positioned outside the body and near the pump. The external controller may have a magnet magnetically coupled to the rotor to rotate it.

An implantable pump includes a rigid housing with an oblate spheroid shape and having an inner chamber divided by a movable elastomeric membrane into a gas sub-chamber which is connectible through a drive line to an external pneumatic source, and a blood sub-chamber which is connectible through a graft assembly to an anatomical heart. The housing includes a blood port opening oriented at an angle and at the upper apex of the housing and connected to the blood sub-chamber, and a gas port opening to the gas sub-chamber that is situated at a lower apex of the housing. The pump is provided with a drive line that includes a gas conduit and a heart sensor, the drive line connectible to a drive system that is capable of delivering gas flow through the drive line gas conduit in response to signals driven by the heart sensor.

In various embodiments, the present invention provides a blood flow assist device comprising an axial flow rotary pump, said pump comprising a rotatable impeller assembly comprising a hub and one or more impeller blades, and an electromagnetic stator operable to drive rotation of the impeller assembly. The electromagnetic stator assembly comprises electromagnetic windings supported on a supporting structure, said supporting structure being configured for engagement with an interior wall of, or replacement of a segment of, a vessel of a human body during use. Also provided are blood flow assist systems incorporating such devices in combination with a power supply module configured for connection to the blood flow assist device to supply power to the device.

An implantable pump includes a rigid housing with an oblate spheroid shape and having an inner chamber divided by a movable elastomeric membrane into a gas sub-chamber which is connectible through a drive line to an external pneumatic source, and a blood sub-chamber which is connectible through a graft assembly to an anatomical heart. The housing includes a blood port opening oriented at an angle and at the upper apex of the housing and connected to the blood sub-chamber, and a gas port opening to the gas sub-chamber that is situated at a lower apex of the housing. The pump is provided with a drive line that includes a gas conduit and a heart sensor, the drive line connectible to a drive system that is capable of delivering gas flow through the drive line gas conduit in response to signals driven by the heart sensor.

A blood flow assist device comprising an axial flow rotary pump, said pump comprising a rotatable impeller assembly 3 comprising a hub and one or more impeller blades 15, and an electromagnetic stator

The present invention relates to a pump (1) implantable in a human or animal body and comprising : an airtight casing (10), a dielectric elastomer tube (20) extending within said casing (10), arranged so that a volume (22) within said dielectric elastomer tube (20) is modified when a voltage is applied to said dielectric elastomer tube; a negative pressure chamber (N) between said dielectric elastomer tube (20) and said casing (10). The casing comprises two lateral edges (100a, 100b). The dielectric elastomer tube (A) is longitudinally pre-strained between those lateral edges.

The present disclosure relates to stimulation systems, comprising, e.g., an implantable medical device (IMD), such as an implantable pulse generator configured to deliver electrical stimulation to one or more nerves of a subject, or an implantable pump configured to administer one or more active agents. In some aspects, the IMD is configured to store one or more clinical state parameters (e.g., a clinical workflow stage) and / or to advertise or transmit the stored one or more clinical state parameters to a clinician programmer device. One or more settings of the IMD, and / or parameters of the administration of electrical stimulation or the active agent(s), may be set based on the one or more clinical state parameters (e.g., a clinical workflow stage), e.g., either automatically or based on instructions provided by the clinician programmer device.

Disclosed is a complex including: cellulose nanocrystals; at least one β-cyclodextrin molecule; and at least one curcumin molecule, suitable for use in the treatment of any kind of peripheral neuropathies. Further disclosed is a pharmaceutical composition including at least the complex and at least one pharmaceutically acceptable excipient. Also disclosed is the use of the complex or the pharmaceutical composition, in particular in the form of a hydrogel, a subcutaneous implant, an implantable pump, an implanted biofunctionalized nerve conduit, to improve the treatment compliance, to allow an extended release of the complex and to obtain better pharmacokinetics.

The present disclosure relates to stimulation systems, comprising, e.g., an implantable medical device (IMD), such as an implantable pulse generator configured to deliver electrical stimulation to one or more nerves of a subject, or an implantable pump configured to administer one or more active agents. In some aspects, the IMD is configured to store one or more clinical state parameters (e.g., a clinical workflow stage) and / or to advertise or transmit the stored one or more clinical state parameters to a clinician programmer device. One or more settings of the IMD, and / or parameters of the administration of electrical stimulation or the active agent(s), may be set based on the one or more clinical state parameters (e.g., a clinical workflow stage), e.g., either automatically or based on instructions provided by the clinician programmer device.

Disclosed are a fluid drainage devices and methods of use for drainage of edematous tissues of a patient. The devices include an inlet catheter comprising a plurality of lumens configured to receive fluid from the edematous tissues, wherein the plurality of lumens run axially parallel in the inlet catheter; an outlet catheter configured to be anchored at a sink; an implantable pump coupled to the inlet catheter and the outlet catheter, the pump having a rotating portion including a permanent magnet, the rotating portion configured to rotate in response to a magnetic force external to the patient to move fluid from the inlet of the inlet catheter to the second end of the outlet catheter; and an external controller configured to transcutaneously couple to the permanent magnet of the rotating portion to apply the magnetic force to the implantable pump.

Systems and methods are provided for a bodily fluid management system for pumping bodily fluid such as lymph. The bodily fluid management system may include an implantable pump with a rotor having a magnetic portion and inlet and outlet tubes that connect to a fluid chamber. The fluid chamber has a volume that can be selectively reduced or increased via the rotor. The rotor is designed to periodically open and close kinking valves at each of the inlet and outlet tube to permit bodily fluid to enter the fluid chamber during an intake cycle and exit the fluid chamber during a discharge cycle. The magnetic portion of the rotor may be caused to rotate by an external controller that is positioned outside of the body and adjacent to the pump. The external controller may have a magnet that magnetically interfaces with the rotor to cause the rotor to rotate.

The present invention relates to an implantable device for improving the pump function of the heart of a human patient by applying an external force on the heart muscle. The implantable device comprises at least one implantable pump device comprising: A fluid, A first reservoir having a first volume and at least one movable wall portion, for varying said first volume, and A second reservoir being in fluid connection with said first reservoir. Wherein said implantable pump device is adapted to allow free flow of fluid between said first reservoir and said second reservoir, and wherein said first reservoir, said second reservoir and said fluid connection forms a fully implantable closed pump device, and wherein said fully implantable closed pump device is adapted to transfer force from said first reservoir to said second reservoir.

The invention relates to a complex comprising: - cellulose nanocrystals; - at least one β-cyclodextrin molecule; - at least one curcumin molecule, for use in the treatment of any type of peripheral neuropathy. The invention also relates to a pharmaceutical composition comprising at least said complex and at least one pharmaceutically acceptable excipient. The invention further relates to the use of the complex or pharmaceutical composition, in the form in particular of a hydrogel, subcutaneous implant, implantable pump, implanted biofunctionalized nerve conduit, to improve treatment compliance, allow prolonged release of the complex and obtain better pharmacokinetics.

An implantable pump system is provided, including an implantable blood pump suitable for use as a partial support assist device, the system further including an extracorporeal battery and a controller coupled to the implantable pump, and a programmer selectively periodically coupled to the controller to configure and adjust operating parameters of the implantable pump. The implantable pump includes a flexible membrane coupled to an electromagnetic actuator including a magnetic assembly and electromagnetic assembly, so that when the electromagnetic assembly is energized, the electromagnetic assembly causes wavelike undulations to propagate along the flexible membrane to propel blood through the implantable pump. The controller may be programmed by a programmer to operate at frequencies and duty cycles that mimic physiologic flow rates and pulsatility while operating in an efficient manner that avoids thrombus formation, hemolysis and / or platelet activation.

In various embodiments, the present invention provides a blood flow assist device comprising an axial flow rotary pump, said pump comprising a rotatable impeller assembly comprising a hub and one or more impeller blades, and an electromagnetic stator operable to drive rotation of the impeller assembly. The electromagnetic stator assembly comprises electromagnetic windings supported on a supporting structure, said supporting structure being configured for engagement with an interior wall of, or replacement of a segment of, a vessel of a human body during use. Also provided are blood flow assist systems incorporating such devices in combination with a power supply module configured for connection to the blood flow assist device to supply power to the device.

Systems and methods for performing Direct Sodium Removal (DSR) therapy are provided in which an implantable device includes a pump coupled to an inlet catheter designed for placement in a patient's peritoneal cavity, an outlet catheter designed to be coupled to the patient's bladder, and is operably coupled to an analyte sensor, the pump programmed to transfer and / or cease transfer of fluid from the patient's peritoneal cavity to the patient's bladder for voiding responsive to a level of analyte detected by the analyte sensor. In addition, the system may include a processor that computes an amount of analyte transferred per pumping session.

Systems and methods for controlling an implantable pump are provided. For example, the exemplary controller for controlling the implantable pump may only rely on the actuator's current measurement. The controller is robust to pressure and flow changes inside the pump head, and allows fast change of pump's operation point. For example, the controller includes, a two stage, nonlinear position observer module based on a reduced order model of the electromagnetic actuator. The controller includes an algorithm that estimates the position of the moving component of the implantable pump based on the actuator's current measurement and adjusts operation of the pump accordingly. Alternatively, the controller may rely on position measurements and / or velocity estimations.

An implantable pump for pumping body fluid has a piston which is reciprocatingly movable along a stroke axis, with a piston head, a wall opposite the piston head, and a pump volume enclosed between the piston head and the wall. A stroke movement of the piston causes a change in pump volume and delivery of body fluid between an inlet and an outlet. The piston has a disc, the underside of which forms the piston head, and an elastic ring collar that protrudes radially from the disc. An inner periphery of the ring collar is fixedly and fluid-tightly connected to an outer periphery of the disc, and at an outer periphery of the ring collar is fixedly and fluid-tightly connected to the wall. The disc rests via the ring collar on the wall so as to be reciprocatingly movable relative to the wall and fluid-tightly connected to the wall.