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Preparation method of Trichosanthes kirilowii Maxim oral liquid

A Gualou oral liquid and a technology for oral liquid are applied in the field of preparation of Gualou oral liquid, and can solve the problems of easy recurrence, inconvenience in filling different types of medicine bottles, poor practicability and the like

Inactive Publication Date: 2020-03-24
ANHUI ZANJIATIAN ECOLOGICAL AGRI CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Traditional Chinese medicine uses "Dachengqi Decoction", rhubarb, senna, magnesium sulfate, etc. to laxative stools, which are still dry and hard after relapse; "Kaisaitong" relieves the symptoms, but has the disadvantages of treating the symptoms but not the root cause, unstable curative effect, low cure rate, generally 20%, and easy recurrence; and in the process of preparing Gualou Oral Liquid, it needs to be filled, but The existing filling equipment has a low degree of automation, it is not convenient to cover and screw the cap, and it cannot be used continuously. The liquid medicine is placed outside for a long time, resulting in a decline in its efficacy, and the existing equipment is not convenient for different types of medicine bottles. filling, resulting in poor usability

Method used

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  • Preparation method of Trichosanthes kirilowii Maxim oral liquid
  • Preparation method of Trichosanthes kirilowii Maxim oral liquid
  • Preparation method of Trichosanthes kirilowii Maxim oral liquid

Examples

Experimental program
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Effect test

Embodiment 1

[0039] see Figure 1-7 Shown, a kind of preparation method of Gualou oral liquid, comprises the following steps: Step 1, the weighing of raw material: by weight, weigh 19 parts of Huoxiang, 56 parts of Magnolia officinalis, 19 parts of Radix Paeoniae Alba, leather whistle 9 parts, bellflower 9 parts, almond 14 parts, melon 60 parts, angelica 9 parts, peach kernel 19 parts;

[0040] Step 2, preparation of oral liquid: combine the above raw materials, add water to decoct twice, combine the decoction, concentrate under reduced pressure to an extract with a relative density of 1.15 at 65°C, add ethanol so that the volume percentage of the alcohol content reaches 75% , stirred, left standing, filtered, and the relative density of the filtrate was 1.25 when the filtrate was concentrated under reduced pressure to 65° C., and ethanol was recovered to obtain a concentrated solution, which was prepared into an oral liquid by adding water and auxiliary materials to the concentrated solut...

Embodiment 2

[0046] see Figure 1-7 Shown, a kind of preparation method of Gualou oral liquid, comprises the following steps: Step 1, the weighing of raw material: by weight, weigh 20 parts of Huoxiang, 60 parts of Magnolia officinalis, 20 parts of Radix Paeoniae Alba, 10 parts of leather whistle 9 parts of bellflower, 14 parts of almond, 80 parts of melon, 9 parts of angelica, 21 parts of peach kernel;

[0047] The working method of steps 2-4 is the same as implementation 1.

Embodiment 3

[0049] see Figure 1-7 Shown, a kind of preparation method of Gualou oral liquid, comprises the following steps: Step 1, the weighing of raw material: by weight, weigh 21 parts of Huoxiang, 64 parts of Magnolia officinalis, 21 parts of Radix Paeoniae Alba, 10 parts of leather whistle 11 parts of bellflower, 16 parts of almond, 80 parts of melon, 13 parts of angelica, 21 parts of peach kernel;

[0050] The working method of steps 2-4 is the same as implementation 1.

[0051] Get 60 ICR mice, with compound diphenoxylate tablet 50m / kg gavage model, continuous 10 days, during normal diet, form constipation; Divide into four groups then, use respectively the oral liquid prepared by embodiment 1-3 and Traditional liquid medicine feeding, for 5 consecutive days, observe the constipation of mice;

[0052] group Number of animals / only Feeding time / day Constipation Example 1 15 5 12 recovered, 3 constipated Example 2 15 5 11 recovered, 4 constipated ...

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Abstract

The invention discloses a preparation method of Trichosanthes kirilowii Maxim oral liquid, comprising the following steps: step 1, weighing raw materials: weighing 19-21 parts of Agastache rugosus, 56-64 parts of Mangnolia officinalis, 19-21 parts of white paeony root, 9-10 parts of delavay soapberry pericarp seed, 9-11 parts of Platycodon grandiflorum, 14-16 parts of apricot kernel, 60-80 parts of Trichosanthes kirilowii Maxim, 9-13 parts of Angelica sinensis, and 19-21 parts of peach kernel. Trichosanthes kirilowii Maxim added in the invention has the effects of moistening lung for removingphlegm, smoothing intestine and relaxing the bowels and is mainly used for cough caused by dryness and phlegm and constipation due to intestinal dryness; Mangnolia officinalis has therapeutical effecton diseases such as dyspepsia and qi stagnation, abdomen distension and constipation, damp retention in middle-jiao and the like; Angelica sinensis has effects of invigorating qi and blood, regulating menstruation and relieving pain, moistening dryness and smoothing intestine; white paeony root has efficacy of warming yang and eliminating dampness, tonifying body deficiency, strengthening spleenand stomach, etc.; and peach kernel has the effect of promoting digestion and removing food retention. By combining the various medicines to achieve the effects of tonifying middle-Jiao and qi, tonifying spleen and promoting circulation, the oral liquid of the invention is used for treating constipation.

Description

technical field [0001] The invention relates to the technical field of Gualou oral liquid, in particular to a preparation method of Gualou oral liquid. Background technique [0002] Gualou, alias: Trichosanthes Lou, Tanggualou, Lougua. Trichosanthes, a perennial climbing herb. Xi was born in the deep mountains and thorny cliffs. Its fruit, peel, kernel (seed), and rhizome are all good Chinese herbal medicines. The oral liquid prepared by Gualou has the functions of clearing heat and eliminating phlegm, widening the chest and dispelling stagnation, moistening dryness and smoothing the intestines. For lung-heat cough, turbid yellow thick phlegm, chest obstruction and heartache, chest fullness, breast abscess, lung abscess, intestinal abscess swelling and pain, constipation. [0003] Modern people have a fast-paced life and high pressure, and often suffer from constipation symptoms. Traditional Chinese medicine uses "Dachengqi Decoction", rhubarb, senna, magnesium sulfate,...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/77A61K9/08A61P1/10B67C7/00B67C3/24B67C3/26B67B3/20
CPCA61K9/0095A61K36/232A61K36/346A61K36/428A61K36/532A61K36/575A61K36/65A61K36/71A61K36/736A61K36/77A61K47/26A61K47/36A61K2236/331A61K2236/39A61K2236/53A61P1/10B67B3/20B67C3/24B67C3/26B67C7/00A61K2300/00
Inventor 段林森段士平高琳琳蒋涛
Owner ANHUI ZANJIATIAN ECOLOGICAL AGRI CO LTD
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