The invention provides a combined process of filling and screw capping nail polish, relating to the technical field of cosmetic packaging machinery, filling machinery and automatic production equipment, and particularly relating to combined process of filling and screw capping nail polish. The combined process comprises the following steps: conveying bottles, sequential feeding the bottles, positioning the bottles, filling through a peristaltic pump, anti-leakage blocking, automatically filling steel balls, automatically feeding hair brushes, automatically conveying caps, automatically capping, automatically screwing the caps, automatically discharging the bottles, manually putting bottle sleeves and automatically pressing the bottle sleeves. The combined process can be used for relieving labor intensity of workers, improving the filling precision and production quality, enhancing the labor efficiency and accelerating the production speed.