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55 results about "Laxative" patented technology

Laxatives, purgatives, or aperients are substances that loosen stools and increase bowel movements. They are used to treat and prevent constipation. Laxatives vary as to how they work and the side effects they may have. Certain stimulant, lubricant and saline laxatives are used to evacuate the colon for rectal and bowel examinations, and may be supplemented by enemas under certain circumstances. Sufficiently high doses of laxatives may cause diarrhea.

Defecation device for digestive department

InactiveCN119344821ASurgeryGuide tubeLaxative
The invention discloses a defecation device for the gastroenterology department, and relates to the technical field of equipment for the gastroenterology department, the defecation device comprises a defecation pipe and a connecting pipe, the bottom of the defecation pipe is provided with a sealing cover, the connecting pipe is slidably connected with the defecation pipe, the top of the connecting pipe is provided with a miniature probe, and the inner wall of the defecation pipe is fixedly provided with a power assembly; the scraping assembly is installed on the periphery of the connecting pipe and comprises an air bag installed on the periphery of the connecting pipe and a micro inflation pump installed on the inner wall of the connecting pipe, the micro inflation pump is connected with the air bag through an air guide pipe, and the adjusting assembly is installed on the periphery of the defaecation pipe. The adjusting assembly comprises a connecting cylinder slidably mounted in the defecation pipe through a groove, and in order to adjust the extension state of the air bag more conveniently and rapidly, when the abutting rod is manually rotated, the abutting plate is pushed to slide on the mounting column and the rotating disc is rotated, the abutting plate moves along the inclined face and the step of the abutting block, the height of the lifting plate is controlled, and the air bag can extend to different degrees.
Owner:SHANDONG PROVINCIAL HOSPITAL AFFILIATED TO SHANDONG FIRST MEDICAL UNIVERSITY (SHANDONG PROVINCIAL HOSPITAL)

AI reminding method for gastroenterology department enteroscope patient to take laxative

The invention relates to the technical field of medical health and artificial intelligence, and discloses an AI reminding method for a gastroenterology department enteroscope patient to take a laxative, comprising the following steps: S1, guiding the patient to enter an AI interaction interface through a two-dimensional code or an applet entry; s2, generating a personalized medication scheme according to the basic information and the real-time data input by the patient; s3, ensuring that the patient completes an intestinal tract preparation process through a staged guidance and real-time reminding function; s4, performing abnormal reaction identification according to real-time feedback data input by the patient, and adjusting subsequent operation suggestions; and S5, screening potential drug interaction through the integrated drug database, and providing a safe drug use prompt. Personalized data such as age, weight, basic diseases, daily medication and daily work and rest of a patient are collected through the personal information input module, the medication scheme generation module calls a preset algorithm to calculate the optimal medication dosage, medication time nodes are determined, and diet suggestions are generated.
Owner:NINGBO FIRST HOSPITAL

Laxative

To provide a laxative that is safe and more excellent in bowel movement improving effect.SOLUTION: A laxative is provided according to one embodiment of the present invention. The laxative includes yeast and / or a yeast-derived ingredient.SELECTED DRAWING: None
Owner:KINS KK

Formulations of guanylate cyclse c agonists and methods of use

The invention provides low-dose formulations of guanylate cyclase-C (“GCC”) agonist peptides and methods for their use. The formulations of the invention can be administered either alone or in combination with one or more additional therapeutic agents, preferably an inhibitor of cGMP-dependent phosphodiesterase or a laxative.
Owner:BAUSCH HEALTH IRELAND LTD

Traditional Chinese medicine formula for relaxing bowel and preparation method thereof

The invention relates to the technical field of preparation of traditional Chinese medicines for relaxing bowel, in particular to a traditional Chinese medicine formula for relaxing bowel, which comprises the following components in parts by weight: 20-40 parts of black sesame, 10-20 parts of oil angelica sinensis, 10-15 parts of fructus cannabis, 10-20 parts of bunge cherry seed, 10-20 parts of radix rehmanniae, 10-15 parts of radix scrophulariae, 10-30 parts of radix ophiopogonis, 5-15 parts of immature bitter orange, 10-30 parts of bighead atractylodes rhizome, 5-10 parts of liquorice, 10-20 parts of peach kernel, 10-20 parts of almond, 10-20 parts of snakegourd seed, 10-20 parts of mangnolia officinalis, 5-15 parts of rheum officinale, 5-10 parts of mirabilite and 20-30 parts of raw honey. The traditional Chinese medicine is prepared from 0-30 parts of mulberry, 0-40 parts of radish leaves, 0-15 parts of herba cistanche and the balance of water. The traditional Chinese medicine composition can enhance peristalsis of intestinal tracts, accelerate movement of excrement in the intestinal tracts, facilitate defecation, nourish components of intestinal mucosa, and help to protect health of the intestinal tracts and reduce constipation.
Owner:苏少华

Colon purgation tablet and colon purgation containing same

PendingCN121443276ADigestive systemCoatingsBowel cleansingMedication adherence
The present invention can provide: a colon purgation tablet having a gel-forming coating layer containing an alginate as a main component, the gel-forming coating layer being introduced into an uncoated tablet containing an osmotic substance, the present invention relates to an uncoated tablet, and more particularly, to an uncoated tablet, such that the osmotic substance contained in the uncoated tablet disintegrates rapidly while preventing damage to gastric mucosa due to a physical collision between the tablet and the gastric mucosa, and thus provides an excellent intestinal cleansing effect. The colon purgation tablet according to the present invention can exhibit an excellent intestinal cleansing effect even at a small dose, and can further improve drug compliance by selectively miniaturizing the tablet or introducing an adhesive to improve a coating layer.
Owner:PHARMBIO KOREA CO LTD

BLOWBY GAS DUCT

Blow-by gas venting device, comprising: a blow-by gas line (23) extending from a height position of an upper end part of an internal combustion engine (1) to a height position of a lower end part of the internal combustion engine (1), wherein the blow-by gas line (23) is exposed to and subjected to outside air, wherein the blow-by gas line (23) is divided into an upstream gas line (25) and a downstream gas line (26) at a position in the middle thereof; a heating chamber (24) connected between the upstream gas line (25) and the downstream gas line (26) and provided in a flywheel housing (10) of the internal combustion engine (1), the heating chamber (24) being configured to heat blow-by gas; and an oil separator (22) which is provided and configured at the height position of the upper end part of the internal combustion engine (1) to separate oil from the blow-by gas, wherein the upstream gas line (25) has an inlet part (27) connected to the oil separator (22) and an outlet part (29) connected to the heating chamber (24), and the downstream gas line (26) has a further inlet part (31) connected to the heating chamber (24) and a further outlet part (33) released to an atmosphere.
Owner:ISUZU MOTORS LTD

Disposable brewing bag for oral laxative

The utility model relates to the technical field of oral laxative brewing equipment, and provides a disposable oral laxative brewing bag which comprises a brewing bag body, a stirrer and an electric stirring base, a brewing cavity used for containing laxative is formed in the brewing bag body, a scale area is arranged on the outer surface of the brewing bag body, and the electric stirring base is arranged on the scale area. The scale area is used for measuring the amount of water injected into the brewing cavity, the stirrer is arranged in the brewing bag body and driven by the electric stirring base to rotate, and the electric stirring base is used for bearing the brewing bag body. The brewing bag body serves as a container for containing laxative and water, and compared with a reusable measuring cup, the disposable brewing bag is cleaner; in the preparation process of the laxative, the laxative and quantitative water are added into the brewing bag body, then the brewing bag body can be placed on the electric stirring base to be automatically stirred, and manual long-time stirring is not needed.
Owner:THE UNIVERSITY OF HONG KONG SHENZHEN HOSPITAL

Effervescent laxative composition

An effervescent laxative composition comprising an acid component, an alkaline component, and a polyethylene glycol is disclosed.
Owner:PERRIGO L CO

Colon cleansing composition with enhanced cleansing efficiency and ease of administration

PCT designated stageWO2026005550A1Digestive systemPill deliveryBowel cleansingSide effect
The present invention relates to a colon cleansing composition with improved ease of administration. The composition minimizes side effects caused by excessive ingredient content in conventional colonic laxatives while providing equivalent or superior intestinal cleansing efficacy, thereby remarkably improving patient compliance and ingestion convenience. In addition, as an uncoated tablet requiring no separate coating processes, a preparation that maintains the quality of tablets such as rapid disintegration and does not have a bitter taste can be provided. The present invention provides a pharmaceutical formulation comprising the colon cleansing composition with improved ease of administration and a method for colon cleansing using the formulation, thereby realizing a patient-centered colon cleansing process and ultimately greatly contributing to the improvement of colonoscopy quality.
Owner:MOTHERS PHARMA CO LTD

RETURN UNIT AND WASTEWATER TREATMENT SYSTEM

Return unit (240), wherein the return unit (240) is arranged in an aerobic basin (200) and the return unit (240) comprises a feed section (241), a treatment section (242) and a discharge section (243) which are connected sequentially; wherein the feed section (241) is configured to feed a reflux substance; the treatment section (242) is configured for the deoxidation of the reflux substance supplied through the feed section (241); and the discharge section (243) is configured to discharge the deoxidized reflux substance; wherein the treatment section (242) is positioned at least partially above a ventilation opening (251) of a ventilation device (250); or the treatment section (242) is attached to a surface of the aeration device (250) such that vibration deoxidation of the reflux substance in the treatment section (242) is carried out by using the vibration generated by the aeration device (250) during operation, or the treatment section (242) is driven to vibrate by an impact force from a position below, generated by bubble conveying the aeration device (250), wherein the reflux unit (240) further includes a filter plate (244), the filter plate (244) being arranged in an inner cavity of the treatment section (242), the treatment section (242) being provided with a gas outlet (2421) and a water outlet (320), the gas outlet (2421) being configured to discharge oxygen generated by deoxidation, and the water outlet (320) being configured to discharge a filtrate passing through the filter plate (244), and the gas outlet (2421) being provided with a one-way drain valve, and the one-way drain valve being configured to discharge the oxygen generated by deoxidation unidirectionally to an outside of the treatment section (242), wherein a maximum height of a first connecting opening (2411) formed by the feed section (241) and the treatment section (242) does not exceed 2 / 3 of a maximum height of the treatment section (242), and the first connecting opening (2411) is arranged in an upper position, and a maximum height of a second connecting opening (2431) formed by the discharge section (243) and the treatment section (242) does not exceed 2 / 3 of the maximum height of the treatment section (242), and the second connecting opening (2431) is arranged in a lower position.
Owner:GUANGDONG BRUNP RECYCLING TECH CO LTD +2

Composition containing composite fruit and vegetable enzyme juice and preparation method thereof

The invention discloses a composition containing composite fruit and vegetable enzyme juice and a preparation method thereof. The invention provides a composition containing composite fruit and vegetable enzyme juice, and the composition containing the composite fruit and vegetable enzyme juice comprises the following raw materials by weight: 39-46% of composite fruit and vegetable enzyme juice; 0.35 to 0.5% by weight of a metagen; 10 to 18% by weight of prebiotics; and a plant extract and L-carnitine, wherein the metabiotics comprise bifidobacterium animalis; the prebiotics comprise xylooligosaccharide and galactooligosaccharide. The composition containing the composite fruit and vegetable enzyme juice provided by the invention can achieve obvious effects of weight management, weight loss and body fat control and good effects of promoting excretion and relaxing bowel.
Owner:HEILONGJIANG FEIHE DAIRY CO LTD

Method and apparatus for cutting strand-shaped foodstuffs

Summary: The invention relates to the design of the discharge channel area and a process technology of a cutting machine for strand-shaped food products. The invention aims to develop a new method with a device for cutting strand-shaped foodstuffs, which allows a reduction in the machine length of the cutting machine and thus a reduced space requirement. According to the invention, the problem is solved procedurally by the fact that the cutting machine has two shorter discharge channels (6, 7) that are movable relative to the feed channel (5) and to each other. These discharge channels can be automatically moved into different positions and angles relative to the feed channel (5), allowing the cut food to be moved in and out of the feed plane. During cutting, the feed channel and the respective discharge channel are offset (Fig. 3). According to the invention, the respective discharge channels and the feed channel are arranged to be movable relative to each other, so that an opposite offset (Fig. 4, 4.1) can be created. This allows the sliced ​​portion of the food to be pushed back into the feed channel by the slice support (Fig. 12), and then the other sliced ​​portion of the food to be moved back into the feed plane.
Owner:LEMKE ANDREAS

Acquisition method for virtually cleaned intestinal tract image

[Problem] To provide a method or program for obtaining a virtual large intestine cleansing image that can remove residual matter from large intestine imaging data captured without the use of laxatives. [Solution] The method includes: an image input step, in which a captured image representing a part of a patient's large intestine is input; and a virtual large intestine cleansing step, in which a virtual large intestine cleansing image representing a part of the patient's large intestine with residual matter removed from the captured image is obtained. The invention also provides a program for causing a computer to execute the above method for obtaining virtual large intestine cleansing images.
Owner:BOSTON MEDICAL SCIENCES INC

An artificial intelligence-based real-time evaluation and whole-process management system for bowel preparation quality

The application provides an intestinal preparation quality real-time evaluation and whole-process management system based on artificial intelligence, which comprises the following functions: patient end provides intestinal preparation start time setting, laxative type selection, examination process and matters needing attention query and online consultation function; medical staff end provides patient management, progress and cleanliness score monitoring, early warning processing, data export and message interaction function, wherein the intelligent data acquisition module acquires multi-dimensional data; the artificial intelligence dynamic scoring module analyzes the data based on a deep learning model, generates a cleanliness pre-score and determines a quality grade; the active early warning and intervention module analyzes the data in real time, issues an early warning and provides intervention suggestions; the medical examination result closed-loop verification module receives the doctor's score after colonoscopy, compares and analyzes the pre-score, and optimizes the evaluation model. The application realizes the standardized guidance, active risk early warning and closed-loop optimization management of the intestinal preparation process, effectively improves the preparation quality, guarantees the safety of patients and optimizes the clinical decision-making.
Owner:THE FOURTH AFFILIATED HOSPITAL OF ZHEJIANG UNIV SCHOOL OF MEDICINE

Heat sink element for a power module, a power module and a method for manufacturing such a heat sink element

Heat sink element (1) for an electrical power module (10), comprising - a basic body with a first end face (S1) which, in the installed state, faces a surface to be cooled, and a second end face (S2) opposite the first end face (S1), and - a cooling channel (30, 30') embedded in the base body between the first end face (S1) and the second end face (S2), wherein the cooling channel (30, 30') has an inlet section (31), a deflection section (32) and a discharge section (33), wherein the cooling channel (30, 30') is designed to form a general flow pattern by conveying a cooling medium in the inlet section (31) towards the first end face (S1), transferring it in the deflection section (32) to the discharge section (33) and conveying it in the discharge section (33) towards the second end face (S2), wherein the inlet section (31) has a first flow cross-section (Q1) dimensioned perpendicular to a flow direction (S) and the deflection section (32) has a second flow cross-section (Q2) dimensioned perpendicular to the flow direction (S), wherein a ratio of the second The cross-sectional area (Q2) of the first cross-sectional area (Q1) is less than 0.5, preferably less than 0.4 and especially preferably smaller than 0.3.
Owner:ROGERS GERMANY

Transport line system, chemical energy conversion system and use of the transport line system

The invention relates to a transport line system (10) for transporting at least two fluids, the transport line system (10) comprising a main transport line (20) for transporting a first fluid and at least one inner retrofit transport line (30) for transporting a second fluid, wherein the at least one inner retrofit transport line (30) is subsequently installed within the main transport line (20), wherein the at least one inner retrofit transport line (30) is designed to be flexible at least in sections, and wherein the inner retrofit transport line (30) comprises at least one supply interface (32) for supplying the second fluid and at least one discharge interface (34) for discharging the second fluid.Furthermore, the invention relates to a chemical energy conversion system (100) for the chemical conversion of energy with at least one transport line system (10) and to a use of the transport line system (10) with a chemical energy conversion system (100).
Owner:WESTNETZ GMBH

A physical defecation device

The present invention discloses a physical laxative, comprising an electric laxative head, the electric laxative head comprising a tubular handle, a sewage collecting sleeve, a stirring rod and a driving motor, the sewage collecting sleeve being tubular, the rear end of which is docked with the front end of the tubular handle, the front edge of which is against the patient's anus, the driving motor being installed in the tubular handle, the front end of the stirring rod being inserted into the patient's hard stool, the rear end of which is connected to the driving motor through the sewage collecting sleeve, the front end of the stirring rod being provided with a water spray hole, the rear end of which is provided with a water inlet hole connected to the water spray hole, the water inlet hole being connected to a water supply device, and the rear end of the tubular handle being connected to a sewage pipe. The present invention uses physical stirring and spraying of liquid to break up and soften the hard stool that causes constipation, and then discharges the loose stool through the sewage pipe. This not only can quickly remove hard stool, solve the constipation problem of middle-aged and elderly people, and alleviate the pain of patients, but also can avoid contaminating bedding and reduce the workload of nursing staff.
Owner:张英泽 +1

A medicine-food homologous composition for moistening intestines and relieving constipation, and preparation method and use thereof

The present invention provides a medicine-food composition for moistening the intestine and relieving constipation, and a preparation method and use thereof. Wherein, by weight, the medicine-food composition comprises or consists of the following components: 5-15 parts of desert cistanche, 0.2-0.8 parts of radish seeds, 0.1-0.5 parts of yellow mustard seeds, 5-15 parts of perilla seeds, 0.5-1.5 parts of cassia seeds, 10-20 parts of hemp seeds and 5-15 parts of lactose. The medicine-food composition of the present invention has significant laxative effect and has significant therapeutic effect on patients with constipation.
Owner:HAIHE LABORATORY OF MODERN CHINESE MEDICINE

Traditional Chinese medicine composition for treating Parkinson's disease and preparation method thereof

The invention discloses a traditional Chinese medicine composition for treating Parkinson's disease, which belongs to the technical field of traditional Chinese medicines and comprises the following raw medicinal materials: prepared rhizome of rehmannia, pulp of dogwood fruit, Chinese yam, poria cocos, moutan bark, rhizoma alismatis, cassia twig, radix aconiti lateralis preparata, semen plantaginis, achyranthes root, liquorice, peach kernel, prepared rhubarb and mirabilite. The invention further discloses a preparation method and application of the traditional Chinese medicine composition. The traditional Chinese medicine has the beneficial effects that the radix rehmanniae preparata and the radix aconiti carmichaeli are used as monarch drugs to tonify kidney qi; the fructus corni and the rhizoma dioscoreae help the monarch drug to enhance the kidney tonifying effect, the cassia twig warms yang to help the kidney to gasify, and the radix achyranthis bidentatae and the semen persicae promote blood circulation to remove blood stasis; poria cocos, rhizoma alismatis and semen plantaginis are used for clearing damp and promoting diuresis, moutan bark is used for activating blood, and prepared rhubarb and mirabilite are used for activating blood and relaxing bowels; the liquorice is used as a guide to harmonize the medicines, so that the movement symptoms of PD, RBD and constipation are comprehensively improved.
Owner:GUANGDONG HOSPITAL OF TRADITIONAL CHINESE MEDICINE

Transport pipeline system, chemical energy conversion system and use of the transport pipeline system

The invention relates to a transport line system (10) for transporting at least two fluids, the transport line system (10) comprising a main transport line (20) for transporting a first fluid and at least one inner retrofit transport line (30) for transporting a second fluid, wherein the at least one inner retrofit transport line (30) is subsequently installed within the main transport line (20), wherein the at least one inner retrofit transport line (30) is designed to be flexible at least in sections, and wherein the inner retrofit transport line (30) comprises at least one supply interface (32) for supplying the second fluid and at least one discharge interface (34) for discharging the second fluid.Furthermore, the invention relates to a chemical energy conversion system (100) for the chemical conversion of energy with at least one transport line system (10) and to a use of the transport line system (10) with a chemical energy conversion system (100).
Owner:WESTNETZ GMBH

Application of pitaya probiotic composition in rapidly promoting defecation and maintaining stability of intestinal flora

The invention discloses application of a probiotic composition in rapidly promoting defecation and maintaining intestinal flora stability, and belongs to the field of probiotic supplements. The invention provides a composition with specific components and formula, the composition can quickly promote defecation of adults within 24 hours under the action of probiotics, water-soluble dietary fibers and pitaya powder, and the problem of constipation of patients is quickly solved; meanwhile, the medicine is high in safety, does not contain laxative components, and avoids stimulating intestinal tracts; the three probiotics can balance intestinal flora, so that a patient can keep long-term regular defecation. The bamboo extract powder is added in the preparation process of the powder, so that the flowability of the powder can be improved, and all the components are mixed more uniformly.
Owner:NANJING AURORA BOREALIS BIOTECHNOLOGY CO LTD

Laxative

1. The name of the product of this design: Laxative. 2. Purpose of this design product: used to assist defecation. 3. The design key point of this appearance design product lies in the shape. 4. The picture or photo that best illustrates the design points: three-dimensional picture.
Owner:刘玉亮

A Chinese medicine compound oral liquid for moistening intestines and relieving constipation and preparation method thereof

The invention discloses a Chinese medicine compound oral liquid for moistening the intestine and promoting bowel movement and a preparation method thereof. The oral liquid comprises the following components by weight: 10-50 parts of gardenia, 10-25 parts of sophora japonica seeds, 0.1-10 parts of sea buckthorn juice, 10-100 parts of sucrose, 10-100 parts of honey, 0.1-1 parts of citric acid, 0.5-5 parts of vanillin and 0.5-5 parts of potassium sorbate. The preparation method of the Chinese medicine compound oral liquid for moistening the intestine and promoting bowel movement provided by the invention is simple. The compound liquid is prepared by extracting gardenia and sophora japonica seeds together. The two can synergistically exert good bowel moistening and promoting bowel movement effects and antioxidant effects. The oral liquid has high safety, good taste, appropriate sweet and sour taste, strong stability, can promote gastrointestinal motility, and has obvious therapeutic effect on constipation.
Owner:INNER MONGOLIA MONTESSORI MEDICINE TECH CO LTD

Cooling device, use of a cooling device and blown film system

Cooling device for a film on a blown film system, comprising a first and a second supply device for cooling fluid to the film and a discharge device for the cooling fluid which exerts a suction force on the cooling fluid, characterized in that the discharge device is a longitudinal distributor for distributing the suction force along the longitudinal extent of the rising film.
Owner:REIFENHAUSER GMBH & CO MASCHFAB

Effervescent Laxative Composition

An effervescent laxative composition comprising an acid component, an alkaline component, and a polyethylene glycol is disclosed.
Owner:PERRIGO L CO

Painless gastrointestinal endoscopy doctor-patient interaction system

The invention relates to a painless gastrointestinal endoscopy doctor-patient interaction system, which comprises an interaction system, a medical care client and a user client, and is characterized in that the interaction system is in wireless data connection with the medical care client, and the interaction system is in wireless data connection with the user client. The steps of reservation, diet preparation, laxative preparation and the like can be automatically and intelligently completed, manual intervention is reduced, the medical efficiency is improved, through an automatic and intelligent mode, the labor cost of nurses and the like can be reduced, the operation cost of hospitals is reduced, and the system can automatically and intelligently complete the steps of reservation, diet preparation, laxative preparation and the like according to personal information of patients and suggestions of doctors. According to the painless gastrointestinal endoscopy doctor-patient interaction system, accurate diet guidance, laxative preparation guidance and the like are provided, errors possibly caused by manual guidance are avoided, the examination accuracy is improved, a patient can more conveniently know own examination conditions through the painless gastrointestinal endoscopy doctor-patient interaction system, misunderstanding and dissatisfaction of a doctor are reduced, and the doctor-patient relationship is improved.
Owner:陈铭

Pure traditional Chinese medicine intestine-moistening, bowel-relaxing and qi-tonifying powder and preparation method thereof

The invention discloses pure traditional Chinese medicine intestine-moistening, bowel-relaxing and qi-tonifying powder and a preparation method thereof, the pure traditional Chinese medicine intestine-moistening, bowel-relaxing and qi-tonifying powder comprises a first powder, a second powder and a third powder, and the mass part ratio of the first powder to the second powder to the third powder is 1: 1: 1; the formula of the first powder comprises the following components in parts by mass: 20 to 30 parts of fructus cannabis, 10 to 15 parts of radix astragali seu hedysari and 20 to 30 parts of radix angelicae sinensis; the formula of the second powder comprises 10-14 parts of perilla frutescens, 6-10 parts of pericarpium citri reticulatae and 4-6 parts of pinellia ternate; the formula of the third powder comprises 20-30 parts of common yam rhizome, 10-15 parts of radix aucklandiae, 10-20 parts of hericium erinaceus and 5-10 parts of liquorice; the three kinds of powder are taken in three time periods, work and rest requirements and living habits of most people can be met, the three main effects of relaxing bowel, promoting digestion and nourishing the stomach and tonifying qi can be achieved, and due to the fact that the powder is taken in the specific time period, the medicine effect of taking can be increased, and the medicine property can be improved.
Owner:XINJIANG JUNJIANTANG HEALTH PRODUCTS CO LTD

Preparation method and application of laxative rhizoma anemarrhenae homogeneous polysaccharide

PendingCN121135913AOrganic active ingredientsAntipyreticDiseaseColonic Diseases
The invention belongs to the technical field of biological medicine, and particularly discloses a preparation method and application of laxative rhizoma anemarrhenae homogeneous polysaccharide, the preparation method comprises the following steps: taking rhizoma anemarrhenae total polysaccharide as an initial raw material, performing primary separation on the supernate of the solution through an anion-cation exchange resin column formed by connecting FPA90Cl and IR84 in series, and performing secondary separation on the supernate to obtain the laxative rhizoma anemarrhenae homogeneous polysaccharide. Eluting with distilled water to obtain target crude polysaccharide; further performing gradient elution on supernate of the crude polysaccharide solution through a DEAE Cellulose 52 ion exchange chromatographic column, collecting a main elution peak during elution of 0.6 mol / L NaCl, and performing concentration, distilled water dialysis and freeze drying to obtain high-purity target polysaccharide. According to the invention, the influence of the rhizoma anemarrhenae homogeneous polysaccharide solutions with different concentrations on cell proliferation is evaluated, and the dose-dependent effect is proved; the obvious influence of the polysaccharide on the AQP3 and AQP8 protein levels is proved. The prepared homogeneous polysaccharide can improve the intestinal barrier function, provides a new strategy for treating diarrhea, constipation or colon diseases, and has important clinical value.
Owner:JIANGSU FOOD & PHARMA SCI COLLEGE