The invention discloses an intelligent control system for a large-scale structural component automatic production line. The intelligent control system is characterized by comprising an intelligent machining production line, a production process intelligent control center, a logistics control module, a tool change system control module, a central tool magazine control module, a loading and unloading area control module, a material cache library management module, a tooling management system, a material management system, a process management system, a production planning system and a tool management system. Through the reasonable design of the overall architecture, the intelligent control system structures the overall intelligent management and control mode of a workshop automation production line manufacturing site from three aspects of manufacturing site state data acquisition, process intelligent decision, and overall operational state analysis, so as to solve the large-scale structural component automatic production line manufacturing resources guarantee problem.