The invention relates to an MES system based on intelligent manufacturing management. The system comprises a management layer, an execution layer and an industrial control layer, the management layercomprises a planning layer information system, a centralized control center used for integrating information, KPI indexes used for organization internal management, a mobile APP used for information watching, recording and management, a material analysis platform, a man-machine analysis platform, a yield analysis platform and a tracing platform used for retrieving the output end of a data source.The execution layer comprises a plan schedule; production scheduling elements, plan making, plan decomposition, rule verification, plan adjustment and plan release are arranged in the plan schedule, the output end of the plan schedule is provided with material management, production execution, quality control, equipment management and resource management, and the material management is correspondingly provided with warehouse location modeling for building a storage place according to the production capacity. The system has the advantages that advanced visual monitoring is achieved, real-time information of a warehouse and a factory is reflected in time, field equipment is connected to the Internet to achieve intelligent control, and the system is simple and efficient.