The invention belongs to the technical field of a control system and particularly relates to a hotel guest room intelligent control system, which comprises a power supply module, a control module, an input module, an output module, a communication module, a server, a guest intelligent mobile terminal control system, wherein the control module comprises a main control box, a guest room information issuing system, a multifunctional gate indicating card, a music door bell, a networked power taking switch, a touch screen switch, a slight touch press key switch, a user card and a networked temperature controller, the guest room information issuing system is connected with the main control box through a 485 bus, and the multifunctional gate indicating card, the music door bell, the networked power taking switch, the touch screen switch, the slight touch press key switch, the user card and the networked temperature controller are respectively connected with the main control box. Compared with the prior art, the hotel guest room intelligent control system can realize the control on the environment through adopting various modes such as the slight touch type control panel, the guest intelligent mobile terminal control system terminal and remote control, so the energy saving is realized, and the electric energy waste is reduced. In addition, the hotel guest room intelligent control system adopts the modular design, the mutual interference of the self strong and weak current parts inside the whole system can be reduced, the loop number can be configured according to the guest room loop requirements, and the cost is saved.