The invention discloses a method for preparing colon-cleansing particles used before gynecological surgery and aims to solve the treatment problem before gynecological surgery. The method is characterized in that the colon-cleansing particles are prepared by the following active pharmaceutical ingredients: by weight proportion, horseweed herb, fructus cinnamomi, radix ranunculi ternati, Chinese starjasmine stem, herbof denseflower bulbophyllum, rhizoma polygonati, dipsacus roots, tangerine peel, sunflower flowers, turbo cornutus solander, amblystegium serpens and magnesium sulfate. The method includes the following steps: (1), extracting volatile oil from dipsacus roots, fructus cinnamomi and herbof denseflower bulbophyllum coarse powder for standby use; (2), smashing turbo cornutus solander and amblystegium serpens into fine powder for standby use; (3), adding water in horseweed herb, radix ranunculi ternati, Chinese starjasmine stem, rhizoma polygonati, sunflower flowers and tangerine peel for decoction twice, filtering, combining filtrate, concentrating the filtrate, adding ethanol for deposition, taking supernate, recycling ethanol and concentrating to obtain thick paste; (4), adding the volatile oil obtained in step 1 and the fine powder and magnesium sulfate obtained in step 2 in the thick paste obtained in step 3, uniformly stirring, forming particles, drying and obtaining the colon-cleansing particles. Clinical experiments show that the colon-cleansing particles have good colon-cleansing effect when used before gynecological surgery, and the colon-cleansing particles are worthy of clinical popularization and application.