The application discloses a
lactobacillus rhamnosus capable of significantly increasing the number of enteric neurons and
neuroglial cells and an application thereof, and belongs to the field of microorganisms.The
lactobacillus rhamnosus CCFM1360 has good activity, certain acid and alkali resistance and adhesion, can significantly increase the number of enteric neurons and
neuroglial cells, repair intestinal
barrier function, increase the content of SCFAs in colon contents, increase the number of Treg cells in mesenteric
lymph nodes, reduce the expression level of
inflammatory factors in colon tissues, reduce the
intestinal inflammation level, and relieve the weakened
intestinal motility disorder.