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Pharmaceutical composition for treating livestock diarrhea and preparation method thereof

A composition and drug technology, applied in the field of poultry medicine, can solve problems affecting poultry and livestock egg production, intestinal flora disorder, and inability to be excreted, so as to avoid the formation of drug-resistant strains and have less toxic and side effects , to reduce the residual effect

Active Publication Date: 2014-07-02
QINGDAO AGRI UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although Western medicine antibiotics are fast in stopping diarrhea and have a high cure rate, fewer animals die from dysentery, but the drug residues of feeding antibiotics are relatively heavy. Studies have shown that the drug residues of antibiotics consumed by animals and poultry cannot be excreted, which can easily cause intestinal flora disorder , affecting poultry and livestock egg production

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] Prescription: 300g of Herba Grass, 300g of Humulus, 250g of Pihancao, 200g of Shi Jianchuan, 150g of Pteris chinensis, 150g of Feiyangcao

[0047] Preparation method: Take the Herb Grass, Humulus, Pihancao, Shijianchuan, Fengweicao, and Feiyangcao, add water 12 times the weight of the medicinal materials, heat and boil to extract twice, each time for 1.5 hours, filter, and the filtrate is decompressed When concentrated to 60°C, the measured relative density is 1.10-1.15, let it cool, add ethanol until the alcohol content reaches 60%, let it stand, filter, recover the ethanol from the filtrate under reduced pressure until it has no alcohol smell, continue to concentrate under reduced pressure to 60°C The measured relative density is 1.30-1.35, dried under reduced pressure, pulverized, added with 60 g of dextrin, mixed evenly, and dry-pressed into granules to obtain the product.

Embodiment 2

[0049] Prescription: 600g of Herba Grass, 600g of Humulus, 600g of Pihancao, 750g of Ishimi Chuan, 540g of Pteris vulgaris, 360g of Feiyangcao

[0050] Preparation method: Take the Herb Grass, Humulus, Pihancao, Shijianchuan, Fengweicao, and Feiyangcao, add water 14 times the weight of the medicinal materials, heat and boil to extract 3 times, each time for 1.5 hours, filter, and the filtrate is decompressed When concentrated to 60°C, the measured relative density is 1.10-1.15, let it cool, add ethanol until the alcohol content reaches 50%, let it stand, filter, recover the ethanol from the filtrate under reduced pressure until it has no alcohol smell, continue to concentrate under reduced pressure to 60°C The measured relative density is 1.30-1.35, dried under reduced pressure, pulverized, added with 1800g of sucrose and 600g of dextrin, mixed evenly, granulated with 85% ethanol, dried, and obtained.

Embodiment 3

[0052] Prescription: Cottonwort 4kg, Humulus 4kg, Pihancao 3kg, Ishimi Chuan 3kg, Pteris 1.2kg, Feiyangcao 1.8kg

[0053] Preparation method: Take the Herb Grass, Humulus, Pihancao, Shijianchuan, Fengweicao, and Feiyangcao, add water 10 times the weight of the medicinal materials, heat and boil to extract twice, each time for 1.5 hours, filter, and the filtrate is decompressed When concentrated to 60°C, the measured relative density is 1.10-1.15, let it cool, add ethanol until the alcohol content reaches 70%, let stand, filter, recover the ethanol from the filtrate under reduced pressure until there is no alcohol smell, continue to concentrate under reduced pressure to 60°C The measured relative density is 1.30-1.35, dried under reduced pressure, pulverized, added with 500 g of starch and 100 g of micropowdered silica gel, and mixed evenly to obtain a powder.

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PUM

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Abstract

The invention discloses a pharmaceutical composition for treating livestock diarrhea and a preparation method thereof, and belongs to the field of veterinary medicines. The method is characterized by comprising the following steps: proportioning sowthistle tasselflower herb, scandent hop, daghestan sweetclover herb, salvia chinensis, herba pteridis multifidae and hairy euphorbia according to a certain ratio; extracting and refining; adding auxiliary materials of the preparation to prepare corresponding preparation according to the conventional method. The pharmaceutical composition disclosed by the invention has a good effect when being applied to treatment of the livestock diarrhea.

Description

technical field [0001] The invention belongs to the technical field of poultry medicines, and in particular relates to a pharmaceutical composition with antidiarrheal effect and a preparation method thereof. Background technique [0002] Common clinical dysentery is mainly caused by bacillary dysentery. Bacillary dysentery is referred to as bacillary dysentery. The main clinical manifestations are fever, abdominal pain, diarrhea, tenesmus, and pus and bloody stool. Bacillary dysentery is still one of the frequently-occurring diseases in my country. Shigella is a Gram-negative short bacillus, which is divided into 4 groups and 39 serotypes, and there is no cross-immunity between each group and each type. [0003] Livestock and poultry dysentery is a serious intestinal infectious disease, such as pig diarrhea, piglet yellow and white scour, lamb diarrhea, calf diarrhea, calf paratyphoid, four seasons diarrhea, infectious gastroenteritis, bacterial and viral mixed infection ...

Claims

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Application Information

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IPC IPC(8): A61K36/60A61P1/12A61P31/04
CPCY02A40/70
Inventor 单虎王述柏周传凤秦志华蔡秀磊
Owner QINGDAO AGRI UNIV
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