52 results about "Abdominal discomfort" patented technology

Methods for treating constipation-predominant irritable bowel syndrome comprise administering to a patient in need thereof a polymeric proanthocyanidin composition from a Croton species or Calophyllum species in an amount sufficient to treat constipation-predominant irritable bowel syndrome (c-IBS). Treatment of c-IBS includes the treatment of the constipation component of c-IBS as well as the pain and abdominal discomfort associated with c-IBS. In one embodiment, the polymeric proanthocyanidin compound is crofelemer. In addition, methods for treating alternating constipation-predominant / diarrhea-predominant irritable bowel syndrome are an alternative embodiment of the invention.

The present invention provides methods for treating diarrhea-predominant irritable bowel syndrome comprising administering to a patient in need thereof, an inhibitor of chloride-ion transport in an amount sufficient to treat diarrhea-predominant irritable bowel syndrome (d-IBS). Treatment of d-IBS includes the treatment of the diarrhea component of d-IBS as well as the pain, abdominal discomfort and other symptoms associated with d-IBS. In one embodiment, the inhibitor of chloride-ion transport is crofelemer.

The invention discloses a simethicone solid self-emulsifying preparation. The preparation is prepared from, by weight, 2.0-6.0% of simethicone, 2.0-30.0% of emulsifier, 1.0-20.0% of auxiliary emulsifier, 50.0-90.0% of pharmaceutically-acceptable solid adsorption material and 0-10.0% of wetting agent. The invention further provides a preparation method of the simethicone solid self-emulsifying preparation. The method is easy and convenient to operate, low in cost and suitable for industrial production; the obtained product has the advantages of being good in taste, uniform in distribution, high in solubility, stable in quality and the like; the preparation is rapid in dissolution, easy to take, rapid in effect and suitable for the aged, children and people who have difficulty in swallowing, the compliance of patients is increased, and the preparation has more advantages on the aspects of packaging, carrying, transporting and the like compared with a traditional liquid simethicone suspension and emulsifier and has good application prospects on the aspects of treating symptoms such as abdominal distension, abdominal discomfort, dyspepsia and postoperative abdominal distension caused when gas gathers in the abdomen.

The invention discloses a simethicone dry suspension and a preparation method thereof. The simethicone dry suspension contains 4% simethicone by mass fraction and a pharmaceutically acceptable carrier. The simethicone dry suspension provided by the invention The preparation method has the advantages of simple operation and low cost, and is suitable for industrial production. The obtained product has the advantages of good taste, uniform distribution, good solubility, stable quality, etc. It is not only instant and easy to take, but also has a quick effect, and is suitable for the elderly, children and those with dysphagia. , increases the patient's compliance, and is more advantageous and more convenient than traditional liquid simethicone suspensions and emulsions in packaging, carrying, transportation, etc., for the treatment of abdominal distension caused by gas accumulation in the abdomen, abdominal Discomfort, indigestion, postoperative abdominal distension and other diseases have good application prospects.

The invention discloses a traditional Chinese medicine composition for treating dyspepsia and a preparation method thereof. The traditional Chinese medicine composition mainly comprises the following medicinal materials: radish seed, medicated leaven, malt, rice-grain sprout, stir-fried areca seed, stir-fried haw, chicken's gizzard-membrane, dried orange peel, green tangerine peel, Chinese eaglewood, Szechwan chinaberry fruit, longstamen onion bulb, grassleaf sweelflag rhizome, immature bitter orange, combined spicebush root, nutgrass galingale rhizome, flos rosae rugosae, aspongopus, Szechuan lovage rhizome, turmeric root-tuber, turmeric, officinal magnolia bark, fructus amomi, Chinese dwarf cherry seed, rhubarb, mongolian snakegourd root, ground beeltle, pangolin scale and the like. Thetraditional Chinese medicine composition can be prepared into any common oral preparation according to the conventional traditional Chinese medicine preparation method. The invention can effectively improve symptoms such as dyspepsia, belly malaise or pain, distension, heartburn (acid regurgitation), eructation, apocleisis or deficient eating and uneasiness, the clinic curative effect is assured,the curative effect is remarkable, and the traditional Chinese medicine composition can quickly take effect. The traditional Chinese medicine composition also has the advantages of cheapness, nearly no toxic side effect and the like.

Described herein are compositions and methods relating to the use of a combination of live lactobacilli bacteria, particularly live Lactobacillus acidophilus, live Lactobacillus casei, and live Lactobacillus rhamnosus, for the relief of undesirable gastrointestinal health problems such as irritable bowel syndrome (IBS), abdominal pain, abdominal discomfort, bloating, liquid stools and constipation. The combination of live lactobacilli bacteria can also be used for improving quality of life of a subject suffering from IBS, for the relief of IBS, and / or for the prevention and / or treatment of IBS.