116 results about "Acute gastroenteritis" patented technology

The present disclosure provides methods and compositions for determining whether a patient exhibiting acute gastroenteritis will benefit from treatment with therapeutic agents that inhibit Norovirus genogroup I (GI) or Norovirus genogroup II (GII). The methods disclosed herein are based on detecting Norovirus genogroup I (GI) and Norovirus genogroup II (GII) in a stool sample without extracting viral nucleic acids from a clinical specimen prior to performing real-time reverse transcription PCR. Kits for use in practicing the methods are also provided.

The invention discloses an orally-taking medicine for treating acute gastroenteritis of horses. The orally-taking medicine comprises the following Chinese medicine raw materials by weight percent: 30 of coptis, 30 of Chinese pulsatilla, 50 of andrographis paniculata, 50 of acalypha australis, 50 of purslane, 50 of phoenix-tail fern, 50 of wood avens, 80 of unripe hawthorn, 30 of costustoot, 20 of magnolia officinalis, 30 of pseudo-ginsheng, 20 of brucea javanica and 20 of glycyrrhiza. The preparation method comprises the steps as follows: uniformly mixing the 30 of coptis, the 30 of Chinese pulsatilla, the 50 of andrographis paniculata, the 50 of acalypha australis, the 50 of purslane, 50 of phoenix-tail fern, the 50 of wood avens,the 80 of unripe hawthorn, the 30 of costustoot, the 20 of magnolia officinalis, the 30 of pseudo-ginsheng, the 20 of brucea javanica and the 20 of glycyrrhiza, smashing the mixture, screening the smashed mixture with a sieve of 300 meshes, and storing the medicinal powder in a bottle for standby. The orally-taking medicine provided by the invention has the advantages that the medicinal herb resource of the orally-taking medicine can be obtained easily, the cost is low, the curing speed is high, the effect is obvious, the curing rate is high, the effective rate of treating acute gastroenteritis of horses is 100%, and the curing rate is 100%.

The invention discloses a daphniphyllum calycinum and knees herb dispersible tablet for gastrointestinal health and a preparation method thereof. The traditional Chinese medicinal composition is prepared from daphniphyllum calycinum and knees herb according to a certain weight proportion, can be prepared into dispersible tablets, has the effects of regulating qi, promoting digestion, removing dampness and resolving food stagnation, and is used for treating acute gastroenteritis caused by the weakness of the spleen and the stomach, qi stagnation and dampness retention, as well as dyspepsia symptoms of abdominal distension, abdominal pain, diarrhea and the like caused by the acute gastroenteritis.

The invention provides a quick antiphlogistic and analgesic Chinese herbal preparation, which is prepared from the alcohol extract of the following raw material medicaments in part by weight: honeysuckle flower 0.5-2, pseudo-ginseng 0.5-2, Stephania epigaea 0.5-2, Indian iphigenia bulb 0.5-2, Bixuelin 0.5-2, thunder god vine 0.5-2, common dysosmatis rhizome and root 0.5-2, dandelion 0.5-2, eucommia bark 0.5-2, costustoot 0.5-2, manyflower solomonseal rhizome 0.5-2, Yunnan manyleaf paris rhizome 0.5-2, tall gastrodia tuber 0.5-2, Chinese magnoliavine fruit 0.5-2, wolfberry fruit 0.5-2, plant soot 0.5-2, and one or more of Chinese alangium root 0.5-1, wild Indian buead 0.5-1, obscured homalomena rhizome 0.5-1, rhizoma corydalis 0.5-1, medicinal cyathula root 0.5-1, changium smyrnioide 0.5-1, tuber fleece flower root 0.5-1, clematis root 0.5-1, drynaria rhizome 0.5-1, cortex acanthopanacis 0.5-1, radix asparagi 0.5-1, phytolacca esculenta van houtte 0.5-1, barbed skullcap herb 0.5-1, garden balsam stem 0.5-1, chinese arborvitae twig 0.5-1, Haijinhe 0.5-1, spreading hedyotis herb 0.5-1, lalang grass rhizome 0.5-1, galium aparine L. 0.5-1 and common clubmoss herb 0.5-1. The extract is auburnish black or light black, great bitter and light spicy. The preparation has a remarkable treatment effect on tooth pain and acute gastroenteritis. After 10 milliliters of the preparation can be kept in mouth for 10 minutes and swallowed, pains are relieved. And when the preparation is taken by three times for one day, the pains are removed. Acute gastroenteritis, appendicitis and renal colic can be cured within 1 to 3 days by the preparation. The preparation has certain treatment effect on arthritis, traumatic injuries, burns and other injuries.

Noroviruses are recognized as the most common cause of outbreaks of acute gastroenteritis in humans. Therefore, the present invention relates to peptides or dendrimers that bind Noroviruses and the methods for identifying and synthesizing these peptides. It also relates to the detection of Noroviruses using said peptides or dendrimers formed by them.

A Chinese medicine for treating acute enterogastritis and preventing and treating viral influenza is prepared from 7 Chinese-medicinal materials including atractylodes rhizome, magnolia bark, tangerine peel, pinellia, etc through supercritical CO2 fluid extracting, refining, and preparing orally taken form, aerosol, or injection.

A Chinese medicine in the form of mixture for treating acute gastroenteritis is prepared from calyx-shaped daphniphyllum, salicileaf dockleaved knotweed heab, and the medical carrier chosen from glycerine and sodium hydrogen sulfite.

The invention relates to a building method of a rotavirus infection suckling mouse experiment model. The method concretely comprises the following steps that 7-day-old ICR suckling mice are used as experimental animals; a 1ml improved injector is used; 0.2ml of rotavirus liquid is given in an intragastric administration mode. The model provided by the invention can simulate features of infant rotavirus infection acute gastroenteritis; the rotavirus infection suckling mouse experiment model is fast built; the sufficient number of mice infecting the rotavirus are obtained; the stability is good; the repeatability is realized; the model building success rate is high and is nearly 100 percent. In addition, the technical scheme provided by the invention has the advantages that the weight of the selected low-age animals is light; the obtaining is easy; the used virus dose is small; the experiment cost is reduced; the method is applicable to batch modeling.

The invention relates to a Chinese medicine composition for treating acute gastroenteritis of horse. The Chinese medicine composition is characterized in that an active ingredient is prepared from the following raw materials according to weight portion: 38 to 52 portions of radices curcumae, 38 to 52 portions of radices paeoniae alba, 25 to 35 portions of rhubarb, 25 to 35 portions of tuckahoe and 25 to 35 portions of radices saussureae. Each raw material has the preferential mixture ratio amount: 45 portions of the radices curcumae, 45 portions of the radices paeoniae alba, 30 portions of the rhubarb, 30 portions of the tuckahoe and 30 portions of the radices saussureae. The granularity of the radices curcumae, the radices paeoniae alba, the rhubarb, the tuckahoe and the radices saussureae is between 20 and 200 meshes. The Chinese medicine composition uses the clearing heat and releasing toxin, dampness elimination and anti-diarrhea as a therapeutical principle and has a reasonable formula and a simple preparation process; the adopted Chinese herbal medicine compositions have wide source and low cost; and the medicine has no residue, no toxicity and no side effect and is easy for animal to absorb. The Chinese medicine composition has effects of easing pain and adjusting body function, effectively treats acute gastroenteritis of horse and shortens the convalescent period.

The invention provides a traditional Chinese medicinal formula for treating acute gastroenteritis. The formula is composed of purslane, bitter cress, dried white raddish strips, ginger, fresh cordate houttuynia, hairyvein agrimony, Chinese pulsatilla roots, dried orange peels, and medicated leaven. The above medicaments are immersed in a proper amount of water for 30min first, and then decocted for 30min, with first two decoction solutions mixed well for oral administration in 2 times. One dose of the formula of the invention can be taken per day for 5 days as a treatment course. The formula provided in the invention has the advantages of simple operation and high efficiency.

The invention provides a summer-heat relieving cola, which can prevent gastrointestinal diseases and summertime colds. The summer-heat relieving cola is prepared according to the following steps: preparing ageratum, perilla leaf, ginger and mung bean with the weight ratio of 8-15:8-15:1-2:3-5, decocting and filtering; adding citric acid and lemon essence in a filter liquor for respectively adjusting a pH value and seasoning taste, depositing and then filtering; taking white granulated sugar and distilled water with the weight ratio of 2:1 to prepare simple syrup; and properly adding the simple syrup into the finally-prepared filter liquor to obtain the summer-heat relieving cola. The invention has delicious taste and fragrant smell, and can prevent and treat headache, dizziness, fever, nausea, stomachache, abdominal distention, diarrhea and fatigue caused by summer colds, gastrointestinal type colds, condition diseases and acute gastroenteritis.

The invention relates to black noodles and a processing method of the black noodles. The raw material dry powder is mixed with water solution containing liquidamba formosana hance leaf extractive juice, or one or more powder auxiliary material(s) in black rice, black sesame, black corn, black soya beans and triticale is/are added, and the dry weight of the added auxiliary material(s) accounts for not more than 5% of that of all the raw materials, wherein the liquidamba formosana hance leaf extractive juice is prepared by feeding 80-1200g of liquidamba formosana hance leaves into every 1000g of raw material flour and leaching by feeding 0.8-8 times of water by weight, or cooking by slow fire in the leaching process. The processing method is also used for the preparation including the mixing process of dry powder and water solution of black Chinese and western pastries, black bean vermicelli or black noodles. The black noodles prepared by the invention not only are attractive in taste and rich in melanin, but also have the corresponding effects of the liquidamba formosana hance leaves, and can be used for diseases such as acute gastroenteritis, dysentery, postpartum wind, infantile umbilical wind, carbuncle back, etc.

The invention relates to a Chinese herbal medicine composition for treating common bacterial diseases of chickens. The Chinese herbal medicine composition is a powder prepared from the following raw materials in parts by weight: 4-6 parts of cordate houttuynia, 4-6 parts of folium isatidis, 3-4 parts of oregano, 3-4 parts of juncus roemerianus, 2-4 parts of abrus cantoniensis hance, 1-2 parts of centella asiatica, and 1-2 parts of licorice root. The Chinese herbal medicine composition is used for treating common bacterial diseases of chickens, such as colibacillosis, the chronic respiratory disease, acute gastroenteritis and salmonellosis, and has the characteristics of high cure rate, good effect, safety, no toxic or side effect, and good convenience in use.

The invention belongs to the field of traditional Chinese medicine, and specifically relates to a traditional Chinese medicine composition. The medicine composition is a decoction prepared from the raw materials of, by weight, 5-6g of round cardamom fruit, 8-10g of hawthorn fruit, 3-8g of green tea, 3-5g of chicken's gizzard-membrane, 5-10g of ginger, 3-7g of rice, 3-7g of wheat, 3-5g of corn stigma, and 8-15g of brown sugar. The invention also provides a preparation method of the traditional Chinese medicine composition used for treating diarrhea. The diarrhea-treating traditional Chinese medicine composition provided by the invention is safe, and has the characteristics such as sufficient raw material source, simple preparation, and convenient application. As a result of clinical experiments, with the medicine composition, diarrhea caused by acute gastroenteritis can be rapidly relieved.

A Chinese medicine 'Yanlixiao' in the form of micropill, dispersing tablet, softgel, capsule, dripping pill, effervescent tablet, etc for treating infectious diseases, such as bacterial dycentery, acute tonsillitis, bronchitis, acute eterogastritis and acute mastitis is prepared from cloves leaf or its extract. Its preparing process and quality control method are also disclosed.

The invention relates to a traditional Chinese medicine for treating acute gastroenteritis. The traditional Chinese medicine is prepared from the following raw medicinal materials in parts by weight: 10 parts of herba pogostemonis, 9 parts of radix angelicae, 9 parts of folium perillae, 12 parts of rhizoma atractylodis macrocephalae (stir-fried), 9 parts of pinellia ternata (preparata), 9 parts of dried tangerine peel, 15 parts of poria cocos, 9 parts of cortex magnoliae officinalis (prepared with ginger), 10 parts of liquorice, 10 parts of platycodon grandiflorum, 5 parts of ginger, 9 parts of pericarpium arecae and 15 parts of Chinese date. Clinical experiments prove that the traditional Chinese medicine provided by the invention can be used for safely and effectively treating acute gastroenteritis.

The present invention relates to a syringopicroside preparation and a preparation technology thereof. The preparation contains the syringopicroside with the weight portion of 1 percent to 50 percent and the auxiliary material with the weight portion of 99 percent to 50 percent. The prepared preparation has high biological utilization degree, stable quality and good curative effect. The drug has the bacteriostasis effect with wide spectrum and has good curative effect towards upper respiratory tract infection, enteritis, bacillary dysentery, acute and chronic bronchitis, acute gastroenteritis, mastitis and hepatitis. The present invention has simple and stable preparation technology and is fit for the industrialization production.

The invention belongs to the technical field of medicines, and in particular relates to a traditional Chinese and western medicinal compound preparation for treating acute gastroenteritis and a preparation method thereof. Currently, a chemotherapeutic medicine for treating acute gastroenteritis has the defects of high liver toxicity and poor curative effect in the prior art. The traditional Chinese and western medicinal compound preparation for treating acute gastroenteritis comprises the following components in parts by weight: 10-15 parts of veratrum nigrum, 10-20 parts of notopterygium root, 5-20 parts of sophora japonica, 5-15 parts of scutellaria baicalensis, 5-10 parts of prepared rehmannia, 5-15 parts of lily, 5-15 parts of honeysuckle, 1-10 parts of indometacin, 5-15 parts of medlar, 9-15 parts of costustoot, 9-15 parts of Ligusticum wallichii, 5-15 parts of angelica root, 0.2-9 parts of berberine, 5.5-15 parts of radix paeoniae alba, 6-9 parts of dried ginger, and 10-15 parts of liquorice. The traditional Chinese and western medicinal compound preparation has a good treatment effect on treating or preventing acute gastroenteritis, is low in side effect, and has remarkable clinical application values.

The invention provides spleen strengthening herbal tea containing red dates and black tea. The spleen strengthening herbal tea comprises raw materials in parts by weight as follows: 25-50 parts of the red dates, 10-20 parts of fennel, 5-10 parts of cloves, 6-12 parts of Chinese eaglewood wood, 12-25 parts of ginger, 15-25 parts of pomegranate leaves, 8-15 parts of plantain seeds, 6-9 parts of liquorice roots and 6-12 parts of the black tea. The invention further provides a preparation method of the spleen strengthening herbal tea containing the red dates and the black tea. The spleen strengthening herbal tea containing the red dates and the black tea adopts ingenious matching and reasonable components and has effects of regulating qi-flowing for strengthening the spleen, warming the spleen and the stomach for dispelling cold, moistening the intestines, checking diarrhea, invigorating the spleen for diuresis, resolving dampness and arresting vomiting for chronic diarrhea and acute gastroenteritis diarrhea. The medicinal and edible beverage prepared from selected all natural plants as the raw materials on the basis of the black tea and Chinese herbal medicines adopts a scientific formula, and the product processed and prepared with the modern biotechnology has obvious effect, is convenient to use and has no side effect after long-time taking.

The present invention discloses millet stomach tonifying sesame seed oil. The millet stomach tonifying sesame seed oil is prepared from the following raw materials in parts by weight: 300-320 parts of sesame seeds, 60-70 parts of black beans, 40-50 parts of longans, 30-40 parts of millets, 80-90 parts of wrinkled gianthyssop herb, 40-50 parts of folium perillae, 40-50 parts of radix angelicae dahuricae, 110-120 parts of pericarpium arecae, 110-120 parts of poria cocos, 80-90 parts of rhizoma atractylodis macrocephalae, 40-50 parts of dried orange peels, 80-90 parts of cortex magnoliae officinalis, 80-90 parts of rhizoma pinelliae, 40-50 parts of radix platycodonis, 40-50 parts of liquorice, 50-60 parts of fresh gingers, 40-60 parts of red jujubes, an appropriate amount of water, and an appropriate amount of edible alcohol. The millet is a traditional stomach tonifying excellent product and suitable for the consumptions of people who are not good in intestines and stomach. The essence of the millet is extracted and the wrinkled gianthyssop herb having effects of resolving dampness with aromatics, regulating the flow of Qi and the middle Jiao, and relieving exterior syndrome is combined. The folium perillae and radix angelicae dahuricae are combined to relieve exterior syndrome, dispel pathogenic cold and resolve dampness stasis. The combined use of the three medicines brings out the best in each other in the aspect of relieving exterior syndrome and resolving dampness. The cortex magnoliae officinalis and pericarpium arecae are combined to remove dampness and relieve stasis, and the rhizoma pinelliae and dried orange peels are combined to regulate qi and harmonize stomach, and lower counterflow and check vomiting. The radix platycodonis can open the inhibited lung-energy and disinhibit diaphragms. The cause of dampness stasis is the dysfunction of spleen in transportation, so that the transportation of the spleen can reduce the dampness. Besides, the poria cocos, rhizoma atractylodis macrocephalae, liquorice, red jujubes and other stomach strengthening raw materials are combined to benefit qi and strengthen spleen, and help transportation. The millet stomach tonifying sesame seed oil is suitable for the consumptions of people with exogenous diseases and internal dampness who have gastrointestinal type cold, acute gastroenteritis, etc.

A wind and cold dispelling walnut oil is prepared from, by weight, 250-260 parts of Juglans cathayensis Dode var. formosana (Hayata) A. et R.H.Chang, 30-40 parts of flaxseed, 70-80 parts of Zanthoxylum armatum DC., 50-60 parts of coconut shell, 60-100 parts of prepared aconite root, 40-70 parts of dry ginger, 40-70 parts of ginseng, 40-70 parts of honey-fried licorice root, 60-100 parts of Rhizoma Atractylodis Macrocephalae, 20-35 parts of cinnamon, 40-70 parts of dried orange peel, 20-35 parts of Chinese magnoliavine, 60-100 parts of Poria cocos and 40-50 parts of pinellia tuber. Zanthoxylum armatum DC. added in the preparation process has wind and cold dispelling effects, and aconite root cooperates with dry ginger and cinnamon to realize interior warming and yang restoring, has substantial cold dispelling and lactation promoting efficacies, and also can tonify spleen and stomach, hold central plains and remove phlegm and excessive fluid generated due to yang deficiency water-damp failing transformation; Chinese magnoliavine added in the invention can tonify qi and enrich heart to activate pulses; and 0.15g of musk is adopted, and musk is spicy, goes through twelve meridians, cooperates with sour astriction of Chinese magnoliavine to realize contraction within dissipation and make all drugs rapidly distributed in all the body, and has no deficiency yang dissipation disadvantage. All drugs are combined to realize yang restoration and pulse activation efficacies to return algidity and restore pulses, automatically remove many symptoms, warm middle and dispel cold, and the walnut oil is suitable for being eaten by yang depletion and desertion verging people with rheumatism ostalgia, acute gastroenteritis induced excessive vomiting and diarrhea, shock, heart failure.

The present invention relates to stomach-nourishing panicum miliaceum semen trichosanthis oil which consists of the following raw materials in parts by weight: semen trichosanthis 300-320, black soya beans 60-70, Lactarius deliciosus 40-50, panicum miliaceum 30-40, Agastache rugosa 80-90, Perilla frutescens 40-50, Angelica dahurica 40-50, pericarpium arecae 110-120, poria cocos 110-120, bighead atractylodes rhizome 80-90, dried tangerine peels 40-50, Mangnolia officinalis 80-90, Pinellia ternata 80-90, Platycodon grandiflorum 40-50, liquorice roots 40-50, fresh ginger 40-50, jujubes 40-50, a proper amount of water and a proper amount of edible alcohol. The panicum miliaceum is a top grade traditional stomach-nourishing food, and suitable for people suffering from intestine and stomach deficiency to eat. The stomach-nourishing panicum miliaceum semen trichosanthis oil extracts panicum miliaceum essence, and is cooperated with the Agastache rugosa with effects in removing dampness by means of aromatics, regulating the flow of vital energy and the middle warmer, and relieving exterior syndrome, and complemented with the Perilla frutescens and the Angelica dahurica with effects in relieving exterior syndrome and expelling pathogenic cold, and dissipating dampness and cold; and the three herbs complement each other to enhance the exterior syndrome-relieving and dampness-dissipating effects; and the stomach-nourishing panicum miliaceum semen trichosanthis oil is accompanied with the Magnolia officinalis and the pericarpium arecae with effects in removing dampness and eliminating stagnation, the Pinellia ternate and the dried tangerine peels with effects in regulating qi-flowing for harmonizing stomach, calming adverse-rising energy and arresting vomiting, and the Platycodon grandiflorum with effects in opening the inhibited lung-energy and relieving stuffiness of the chest-diaphragm; the formation of dampness and stagnation is caused by dysfunction of spleen transportation, thus activating spleen energy in transportation can dissipate dampness, and the stomach-nourishing panicum miliaceum semen trichosanthis oil is also accompanied with the poria cocos, the bighead atractylodes rhizome, the liquorice roots, the jujubes and other stomach-strengthening raw materials with effects in replenishing qi to invigorate spleen, and helping transportation and transformation. Therefore, the stomach-nourishing panicum miliaceum semen trichosanthis oil is suitable for people suffering from gastrointestinal cold, acute gastroenteritis and other diseases caused by exogenous pathogenic factors and endogenous wetness-evil to eat.

The invention provides a wind-expelling cold-removing snakegourd fruit seed oil. The snakegourd fruit seed oil is prepared from the following raw materials by weight: 250 to 260 parts of eastern-China wild snakegourd fruit seed, 30 to 40 parts of flaxseed, 70 to 80 parts of Zanthoxylum armatum DC., 50 to 60 parts of cocoanut shell, 60 to 100 parts of processed monkshood, 40 to 70 parts of dried ginger, 40 to 70 parts of ginseng, 40 to 70 parts of honey-fried licorice root, 60 to 100 parts of bighead atractylodes rhizome, 20 to 35 parts of cassia bark, 40 to 70 parts of dried orange peel, 20 to 35 parts of Chinese magnoliavine fruit, 60 to 100 parts of Poria cocos, 40 to 50 parts of pinellia ternate, etc. Zanthoxylum armatum DC. is capable of expelling wind and removing cold; cooperation among monkshood, dried ginger and cassia bark exerts especially great effect on interior warming, yang restoring, cold removing and channel dredging and can strengthen the spleen and stomach, secure Zhongzhou and eliminate phlegm and fluid retention caused by failure of transformation of yang-deficiency water dampness; ginseng and monkshood cooperate with each other to benefit qi and restore yang so as to relieve desertion; Chinese magnoliavine fruit is cooperatively used to tonify qi and heart so as to activate pulse; three li of musk is used, acrid aroma of musk wanders and passes through twelve meridians, and cooperation between acrid aroma of musk and acidity of Chinese magnoliavine fruit, both divergence and astringency are realized and effects of all the traditional Chinese medicines reach all over the body without dispersion of deficient yang; and cooperation among all the traditional Chinese medicines exerts yang-restoring and pulse-activating effects and enables syncope to be treated, pulse to be recovered and all the symptoms to be automatically eliminated. The wind-expelling cold-removing snakegourd fruit seed oil can warm the spleen and stomach to dispel cold and is applicable to people with rheumatic ostalgia, acute gastroenteritis, excess vomiting and diarrhea, shock, heart failure and the like caused by yang depletion almost leading to collapse.

Norovirus is a virus capable of causing acute gastroenteritis. The invention discloses two nano antibodies targeting norovirus capsid protein, and expression, purification and identification of the two nano antibodies. The nanobody targeting the norovirus can be used for environmental monitoring of the norovirus and clinical diagnosis and treatment of norovirus infection.