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30 results about "Human group" patented technology

High throughput and functional screening method for muscle related disorders and biological processes

ActiveUS20180356400A1Compound screeningApoptosis detectionMuscle metabolismMuscle contraction
The invention relates to a method for high throughput screening compounds by using a plurality of automated cell based assays assessing skeletal muscle cells contractility, morphology, and metabolism, in order to predict the efficacy of said compound on a panel of applications linked with muscle physiological and pathophysiological processes, comprising: (i) providing an in vitro culture of myotubes, wherein the in vitro myotubes culture is obtained by the following method: providing a cell culture device allowing the culture of myoblasts or myotubes, depositing said cells from a human donor or human group of donors, in good health or affected by a muscle related disorder, from primary cells, a cell line, an isogenic cell line or differentiated stem cells recapitulating a muscle disorder, on said culture device by using a method allowing the spatial control of cell culture, culturing said cells during a determined incubation time so as to promote a spatially controlled myotube culture; (ii) adding at least one compound to said culture; (iii) after a determined incubation time of the myotubes with said compound, carrying out structural and/or functional readouts of the myotubes to determine the effect of said compound on the myotubes; and (iv) based on said determined effect, predicting the ability of said compound to improve or alter healthy muscle features, or to treat, rescue, or cure muscle disorders, said features or said disorders being linked with muscle contraction, muscle morphology or muscle metabolism.
Owner:CYTOO

Traditional Chinese medicine preparation for reducing blood pressure and regulating blood lipid

A traditional Chinese medicine medicament for lowering the blood pressure and adjusting the blood fat is made from the active component of the tea chromatophore which is extracted and enriched from tea leaves. The characteristics of the invention are that the extracting technique is simple, the concentration rate of the active component is high, and the ointment producing rate is low, thereby the invention is applicable to be made into the advanced medicament types just like the fluid filling hard capsules, the soft capsules and the like. The medicament types detract the extract of the essential medicine sufficiently by the substrates, thereby the invention is beneficial for the absorption, and the oral bioavailability is increased, and further the invention is easy to be accepted by the patients. After the animal experimental certification, the invention has the obvious functions of the blood pressure lowering and the blood fat adjusting. The invention is safe without any toxic side effects. The source of the medicament is extensive, the costs are low, the technique is simple and the invention is easy to spread. The product of the invention can be used as the food or the medicine, the application human groups are extensive, and further the social and the economic benefits are high.
Owner:TIANJIN DANXI TCM INST

Healthcare tea for invigorating stomach, improving digestion, clearing damp, whitening skin, regulating qi-flowing and strengthening spleen, and preparation method thereof

The invention relates to healthcare tea for invigorating stomach, improving digestion, clearing damp, whitening skin, regulating qi-flowing and strengthening spleen, and a preparation method thereof. The healthcare tea comprises the following raw materials in parts by weight: 4 to 35 parts of tangerine peel, 6 to 45 parts of semen coicis, 2 to 30 parts of fructus crataegi, 3 to 40 parts of fructus fortunellae margaritae, 10 to 56 parts of red jujube fruits, and 1 to 20 parts of fructus lycii. The preparation method comprises: cleaning and crushing all the raw materials into 3 to 30 meshes respectively, mixing the raw materials, and then drying the raw materials at the temperature of 60 to 70 DEG C, so as to obtain the healthcare tea. The raw materials of the healthcare tea provided by the invention contain natural active ingredients, formula matching is scientific, the healthcare tea is safe and free from any toxic and side effects, has the effects of invigorating the stomach, improving the digestion, clearing the damp, whitening the skin, regulating the qi-flowing and strengthening the spleen, and is particularly suitable for being drunk by a human group who suffers from weakness of the spleen and the stomach, has a poor appetite, and suffers from tongue coating, abdominal fullness and distention and lacked energy. Besides, the preparation method is simple, the production cost is low, the operability is strong, and the preparation method facilitates subsequent large-scale application.
Owner:厦门花沐春电子商务有限公司
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