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Traditional Chinese medicine preparation for reducing blood pressure and regulating blood lipid

A traditional Chinese medicine preparation and lipid-lowering technology, which is applied in the direction of medical preparations containing active ingredients, drug combinations, and pharmaceutical formulas, can solve the problems of aggravating atherosclerosis, acute myocardial infarction, etc., and achieve the effect of inhibiting platelet aggregation

Inactive Publication Date: 2008-04-30
TIANJIN DANXI TCM INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are very few Chinese and Western medicines that both lower blood pressure and lower lipids, and blood pressure and blood lipids interact and promote each other, aggravating atherosclerosis, and easily causing stroke and acute myocardial infarction

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] Embodiment 1. Preparation of extract

[0017] Prescription tea 100 servings

[0018] Operation: crush the tea leaves, add 6 times 50% ethanol to recover and extract 3 times, each time for 1.5 hours, extract the extract under reduced pressure to recover ethanol until it has no alcohol smell, concentrate to contain crude drug 0.5g / ml, and absorb on the treated macropores Resin column, the resin volume is 1 / 2 of the concentrated solution, the adsorption rate is 2 times the resin volume, wash the column with pure water, then rinse the column with 20% ethanol, desorb with 50% ethanol, the desorption rate is 0.8 times the adsorption rate , The ethanol was recovered under reduced pressure from the stripping solution below 70°C, concentrated to thick, and vacuum-dried to dryness below 70°C, with a yield of 0.7%.

Embodiment 2

[0019] Embodiment 2: preparation of liquid-filled hard capsule

[0020] Prescription Example 1 extract 100 parts

[0021] Accessories salad oil 100 parts

[0022] Operation: Grind on a colloid mill to fully mix the extract and salad oil into one phase, fill it on a liquid-filled hard capsule filling machine, add a sealing tape, and get it. The yield is about 95%, and the weight of the pill is 150mg / pill. Take 1 capsule each time, 3 times a day.

Embodiment 3

[0023] Embodiment 3: soft capsule preparation

[0024] Prescription Example 1 extract 100 parts

[0025] Accessory salad oil 98 parts

[0026] 1 part palm oil

[0027] 1 part beeswax

[0028] Operation: Grind on a colloid mill to fully mix the extract and salad oil into one phase, press it into pellets on a soft capsule press machine, wash the pellets with 95% ethanol, and the finished product rate is about 90%, and the pill weight is 150mg / pill , 1 capsule each time, 3 times a day.

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PUM

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Abstract

A traditional Chinese medicine medicament for lowering the blood pressure and adjusting the blood fat is made from the active component of the tea chromatophore which is extracted and enriched from tea leaves. The characteristics of the invention are that the extracting technique is simple, the concentration rate of the active component is high, and the ointment producing rate is low, thereby the invention is applicable to be made into the advanced medicament types just like the fluid filling hard capsules, the soft capsules and the like. The medicament types detract the extract of the essential medicine sufficiently by the substrates, thereby the invention is beneficial for the absorption, and the oral bioavailability is increased, and further the invention is easy to be accepted by the patients. After the animal experimental certification, the invention has the obvious functions of the blood pressure lowering and the blood fat adjusting. The invention is safe without any toxic side effects. The source of the medicament is extensive, the costs are low, the technique is simple and the invention is easy to spread. The product of the invention can be used as the food or the medicine, the application human groups are extensive, and further the social and the economic benefits are high.

Description

Technical field: [0001] The invention belongs to a traditional Chinese medicine preparation, in particular to a traditional Chinese medicine preparation for lowering blood pressure and regulating fat. Background technique: [0002] Cardiovascular and cerebrovascular diseases are diseases with the highest morbidity, mortality, disability, and recurrence rates in the world, and most of them occur in developing countries. In my country, 1.5 million patients die of stroke every year, 600,000 suffer from coronary heart disease, and 2 million new stroke patients and more than 1 million new coronary heart disease patients are added each year. The World Health Organization predicts that in the next 10 years, 80 million people in China will die from cardiovascular and cerebrovascular diseases and diabetes, and most people with diabetes will die from concurrent cardiovascular and cerebrovascular diseases. Hyperlipidemia will cause atherosclerosis, which will lead to cardiovascular an...

Claims

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Application Information

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IPC IPC(8): A61K36/82A61K9/48A61P9/12A61P9/10A61P3/06A61K127/00
Inventor 孔伶俐魏吉城
Owner TIANJIN DANXI TCM INST
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