Yanlixiao preparation for treating infectious diseases, preparation method, and quality control method

A quality control method and technology for infectious diseases, applied in diseases, respiratory diseases, medical preparations containing active ingredients, etc., can solve the problems of inconvenient taking of capsules, high bioavailability, and insufficient dosage forms, etc., to achieve Good taste, high bioavailability, wide application effect

Inactive Publication Date: 2007-05-09
北京六盛合医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The object of the present invention is to: provide a kind of Yanlixiao preparation for treating infectious diseases and its preparation method and quality control method; Capsules are inconvenient to take, and the dosage forms are not rich enough, and the disintegration is good, and the bioavailability is high; the preparation method provided by the present invention can effectively prepare the required preparations, and ensure that the production process of the obtained preparations is scientific and reasonable; the quality control provided The method can provide relevant production and testing institutions with testing indicators, testing methods, technical methods, etc., so as to better control the quality of the preparation, ensure the safety of medication, better guide production, and make the production process The control is more strict and reasonable, so that consumers can fully understand the product quality

Method used

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  • Yanlixiao preparation for treating infectious diseases, preparation method, and quality control method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0268] Embodiment 1 of the present invention: clove leaf 2233.6g

[0269] Take 2000g of clove leaves, add water and decoct twice, the first time is 2 hours, the second time is 1 hour, the decoction is combined, filtered, the filtrate is concentrated to a clear paste with a relative density of 1.23 to 1.27 at 80°C, dried, crushed, Standby; take the remaining clove leaves 233.6g, grind them into fine powder, add the above-mentioned extract powder and starch with an amount of 100%, mix well, pass through a 100 mesh sieve, and use 95% ethanol to form pellets and coat them , after drying, to obtain pellets, orally, 1.0g to 1.5g each time, 3 to 4 times a day.

Embodiment 2

[0270] Embodiment 2 of the present invention: clove leaf 2233.6g

[0271] Take 2000g of clove leaves, add water and decoct twice, the first time is 2 hours, the second time is 1 hour, the decoction is combined, filtered, the filtrate is concentrated to a clear paste with a relative density of 1.23 to 1.27 at 80°C, dried, crushed, Standby; take the remaining clove leaves 233.6g, grind them into fine powder, add the above extract powder and 80% starch, mix well, pass through a 100 mesh sieve, use 50% ethanol to form pellets, and coat , after drying, the pellets are obtained.

Embodiment 3

[0272] Embodiment 3 of the present invention: clove leaf 2233.6g

[0273] Take 2000g of clove leaves, add water and decoct twice, the first time is 2 hours, the second time is 1 hour, the decoction is combined, filtered, the filtrate is concentrated to a clear paste with a relative density of 1.23 to 1.27 at 80°C, dried, crushed, Standby; take the remaining clove leaves 233.6g, crush them into fine powder, add the above-mentioned extract powder and starch with an amount of 120%, mix well, pass through a 100-mesh sieve, use 95% ethanol to form pellets, and coat , after drying, the pellets are obtained.

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Abstract

A Chinese medicine 'Yanlixiao' in the form of micropill, dispersing tablet, softgel, capsule, dripping pill, effervescent tablet, etc for treating infectious diseases, such as bacterial dycentery, acute tonsillitis, bronchitis, acute eterogastritis and acute mastitis is prepared from cloves leaf or its extract. Its preparing process and quality control method are also disclosed.

Description

technical field [0001] The invention relates to a Yanlixiao preparation for infectious diseases and a preparation method thereof, belonging to the technical field of traditional Chinese medicine. technical background [0002] Clove leaves have the effects of clearing away heat, detoxifying, and reducing inflammation. It is better for infectious diseases such as bacillary dysentery, acute tonsillitis, acute and chronic bronchitis, acute gastroenteritis, and acute mastitis that belong to heat syndrome. Many inventors and pharmaceutical companies have done a lot of research on it, and also provided some therapeutic products, such as: Yanlixiao Capsule, which is a preparation made of clove leaves as the main drug, and has similar effects to clove leaves According to the clinical indications, the clinical effect of treating the above diseases is definite. However, some problems have also been found in the long-term clinical application of this preparation, such as: single prepar...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/61A61K9/00A61K9/02A61K9/06A61K9/08A61K9/10A61K9/14A61K9/16A61K9/20A61K9/46A61K9/48A61K9/50A61K9/70A61P1/12A61P11/00A61P15/14A61P31/04
Inventor 于文风
Owner 北京六盛合医药科技有限公司
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