Combination of lactobacilli for relief of irritable bowel syndrome and for relief of other gastrointestinal disorders

Abstract

Described herein are compositions and methods relating to the use of a combination of live lactobacilli bacteria, particularly live Lactobacillus acidophilus, live Lactobacillus casei, and live Lactobacillus rhamnosus, for the relief of undesirable gastrointestinal health problems such as irritable bowel syndrome (IBS), abdominal pain, abdominal discomfort, bloating, liquid stools and constipation. The combination of live lactobacilli bacteria can also be used for improving quality of life of a subject suffering from IBS, for the relief of IBS, and / or for the prevention and / or treatment of IBS.

Description

technical field [0001] The present invention relates to the field of gastrointestinal disorders, and more particularly to the use of live Lactobacillus bacterial combinations in the relief of undesirable gastrointestinal health problems such as irritable bowel syndrome (IBS), abdominal pain, abdominal discomfort, bloating, liquid stools and constipation the use of. Background technique [0002] Irritable bowel syndrome (IBS) is a chronic relapsing gastrointestinal disorder that affects 5-20% of the US population. A number of risk factors for IBS have been identified, including female gender, psychological issues, stress, food intolerances, and small intestinal bacterial overgrowth (Aagaard et al., 2013). The main symptoms of IBS include abdominal pain, bloating, and changes in bowel habits (Aagaard et al., 2013). The pathophysiology of this syndrome is well-defined, and the syndrome is not accompanied by structural abnormalities of the gut. The quality of life of individu...

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Problems solved by technology

Strong placebo effects, psychological factors, and gender effects make interpretation of findings difficult (Ford and Moayyedi, 2010; Lyra et al., 2016; Moayyedi et al., 2010)

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