The invention provides a compound premix which contains selenium-enriched yeast, ferrous-enriched yeast and zinc-enriched yeast, and belongs to the field of premixes. The premix is mainly prepared from the following ingredients of the selenium-enriched yeast, the ferrous-enriched yeast, the zinc-enriched yeast, ferrous sulfate, copper sulfate, zinc sulfate, manganese sulfate, potassium iodide, cobalt chloride, organic trace minerals, multivitamin, pantothenic acid, nicotinic acid, folic acid, biotin, lysine, compound microecologics, ethoxyquin, antioxidant, 50% choline chloride, bentonite and rice chaff. The premix is reasonable in formula, is not added with antibiotics, and contains multi-active probiotics and selenium-enriched yeast powder, ferrous-enriched yeast powder and zinc-enriched yeast powder, the pig survival rate is high, the pig weight is quickly increased, and the feed conversion efficiency is increased. The premix is contributed to improving the intestinal microecological environment of the pig, the intestinal health is maintained, the pig immunity function is improved, the disease occurrence is reduce, and the pig growth is promoted.