61 results about "Endocarditis" patented technology

A compound of formula (I) wherein R<1> and R<2> are as defined in the description, R<2> being an aromatic group, useful in the treatment and condition selected from the group consisting of the group meningitis and salpingitis, septic shock, disseminated intravascular coagulation, and/or adult respiratory distress syndrome, acute or chronic inflammation, arthritis, cholangitis, colitis, encephalitis, endocarditis, glomerulonephritis, hepatitis, myocarditis, pancreatitis, pericarditis, reperfusion injury, vasculitis, acute and delayed hypersensitivity, graft rejection, and graft-versus-host disease, auto-immune diseases including Type 1 diabetes mellitus and multiple sclerosis, periodonate diseases, interstitial pulmonary fibrosis, cirrhosis, systemic sclerosis, keloid formation tumors which produce IL-1 as an autocrine growth factor, cachexia, Alzeimer's disease, percussion injury, depression, atherosclerosis, osteoporosis in a mammal, including a human.

The invention relates to a cefathiamidine hydrate, a preparation method thereof and application thereof. The crystalline hydrate has high storage stability, and is applicable in preparing medicaments for treating or preventing gram positive or negative bacteria sensitive bacteria, infections of human or animal respiratory system, liver and biliary system, five sense organs and urogenital system, bone and joint infection and soft skin tissue infection caused by the gram positive or negative bacteria sensitive bacteria, and diseases such as endocarditis, ichorrhemia, meningitis and the like.

The invention relates to a lignin compound that could prevent yellow staphylococcal bacteria and B type hemolytic streptococcus, and the medicine combination of the compound. The invention of lignin Morgan dandehon herb acid A and Rufescidride has obviously effect restraining yellow staphylococcal and B type hemolytic streptococcus. It is also respected to prevent the diseases caused by them, like boil, blain, toxicity epidermis necrolysis, pneumonia, etc.

This invention relates to Ligulatrovine A separated from Ligularia actroviolacea that can prevent and treat diseases related to Staphylococcus aureus and beta hemolytic streptococcus, its pharmaceutical salts and drug composition. Ligulatrovine A has significant inhibitive effect on Gram-positive bacteria, and can prevent and treat diseases such as boil, pustule, pneumonia, osteomyelitis, acute myocarditis, endocarditis, meningitis, mastitis, cystitis, pelvic inflammation, urinary inflammation, prostatitis, bacteremia, or abscess in muscle, skin, urogential region or central nervous system caused by Gram-positive bacteria infection.

The invention relates to a cefotetan disodium hydrate and a preparation method and application thereof. The cefotetan disodium hydrate has high storage stability, and is applicable to the preparation of medicines for treating or preventing diseases of the human being or animals caused by gram-positive or gram-negative sensitive bacteria, such as respiratory system diseases, hepatobiliary system diseases, five-sense organ diseases, urinary tract infection, celiac infection, pelvic infection, ichorrhemia, skin tissue infection, bone and joint infections, cephalomeningitis and endocarditis.

Compositions and methods are disclosed for inhibiting the release of a proinflammatory cytokine from a vertebrate cell, and for inhibiting an inflammatory cytokine cascade in a patient. The compositions comprise, for example, high affinity antibodies that specifically bind HMG1 and antigenic fragments thereof. The high affinity antibodies of the present invention and pharmaceutical compositions comprising the same are useful for many purposes, for example, as therapeutics against a wide range of inflammatory diseases and disorders such as sepsis, rheumatoid arthritis, peritonitis, Crohn's disease, reperfusion injury, septicemia, endotoxic shock, cystic fibrosis, endocarditis, psoriasis, psoriatic arthritis, arthritis, anaphylactic shock, organ ischemia, reperfusion injury, and allograft rejection. In addition, the high affinity antibodies of the present inventions are useful as diagnostic antibodies.

The invention discloses a flavonoid glycoside and medical salt and application to prevent Micrococcus pyogenes and beta hemolytic streptococcus, which is characterized by the following: preventing pustule, toxic epidermal decay, acute myocarditis, cystitis, cervicitis and tumour of neutral nerve system; fitting for treating prostatitis, pneumococcus, medullitis and knuckle disease.

The invention discloses a peripheral-leakage prevention stent device with a covering film, a processing method, a skirt hem wrinkling method and a cardiac valve. The stent device comprises a stent, and further comprises a flexible skirt hem. The skirt hem has a spreading state and a piling state, when the skirt hem is in the spreading state, the skirt hem stretches axially and surrounds the outerperiphery of the stent before releasing, and when the skirt hem is in the piling state, the skirt hem is driven by deformation generated when the stent is released and folded and piled in the axial direction of the released stent to form an annular peripheral-leakage prevention blocking part. According to the device, a peripheral-leakage prevention technology is adopted, so that the interventionalstent is more identical to the inner wall of the blood vessel, the stent is not easily displaced and is more stable, the range of applicable people is expanded, the additional risk of an operation isreduced, and complications such as peripheral leakage and thrombus are prevented and treated; better hemodynamic performance is provided, the climbing and covering function of endothelial cells of the host is enhanced, the occurrence probability of endocarditis is reduced, and normal blood supply functions of the heart and blood vessels are restored.

The invention relates to a sodium fusidate powder-injection pharmaceutical composition for injection and a preparation method. Specifically, the invention belongs to the technical field of medicines, relates to a medicine which can be used for treating various infections such as osteomyelitis, sepsis, endocarditis, repeatedly infected cystic fibrosis, pneumonia, skin and soft tissue infections, surgical and traumatic infections and the like caused by various sensitive bacteria, especially staphylococcus, and particularly relates to a pharmaceutical composition such as a freeze-dried powder injection prepared by taking sodium fusidate as an active component. The invention also relates to a preparation method of the pharmaceutical composition. In an implementation scheme, the invention relates to a sodium fusidate powder-injection pharmaceutical composition for injection, which comprises sodium fusidate, a neutral amino acid and an alkaline amino acid. The pharmaceutical composition has excellent pharmaceutical properties.

The invention discloses a traditional Chinese medicine preparation for treating infective endocarditis and a preparation method and belongs to the field of traditional Chinese medicines. The traditional Chinese medicine preparation comprises raw materials of effective constituents as follows: rhubarb, pilular adina herbs, paulownia flowers, pondweed, Lingnan garcinia, Malabar spinach, ligustrum leaves, jujube bark, hops, philippine violet herbs, common dysosmatis rhizomes and roots, malt, winter jasmines, cassia twigs, camphor leaves and Chinese angelica. Selected medicinal materials of the traditional Chinese medicine preparation are properly compatible, and the preparation conforms to traditional Chinese medicine and modern medicine theories, has functions of relieving swelling and pain, clearing away heat, removing toxins, realizing sterilization, diminishing inflammations and realizing nourishing and tonifying effects, is convenient to take, has the good absorbing effect, is free of adverse, toxic and side effects, is clinically verified to have very good relieving and treatment effects on the infective endocarditis and is suitable for clinical treatment of the infective endocarditis and nursing popularization and application.

The invention discloses a new indication of a cefoperazone sodium and sulbactam sodium drug preparation for treating infectious endocarditis. Cefoperazone sodium provided through a specific raw material production process is extremely low in impurity content and significant in pharmaceutical effect, the quality of a preparation product is improved advantageously, the safety and effectiveness of the preparation product are ensured, and application to the aspect of preparing a drug for treating infectious endocarditis is realized.

The invention discloses a cefoxitin sodium new chemical compound entity and a composition thereof, the cefoxitin sodium new chemical compound storage has better stability less hygroscopicity, and is suitable for preparation of drugs for the treatment or prevention of human or animal respiratory tract infection, endocarditis, peritonitis, pyelonephritis, urinary tract infection, blood poisoning and bone, joint, skin and soft tissue infection and the like caused by gram positive or negative bacteria sensitive bacteria.

The invention discloses a stent device with a draped skirt, a machining method, a skirt draping method and a heart valve. The stent device comprises a stent and is also provided with the flexible skirt, wherein the skirt axially extends and surrounds the periphery of the front stent in a spread state, is driven by the deformation during stent release to be closed up and stacked in the axial direction of the released stent and forms an annular peripheral leakage plugging portion in a stacked state. The interventional stent is better anastomosed with the inner wall of the blood vessel by adopting a peripheral leakage preventing technology, the stent is not prone to shifting and is more stable, the application range is widened, the surgical additional risk is reduced, and peripheral leakage,thrombus and other complications are prevented and treated. A better hemodynamic property is provided, a climbing-attaching function of endothelial cells of a host is enhanced, the occurrence probability of endocarditis is reduced, and normal blood supply functions of the heart and the blood vessels are rehabilitated.