Preparation method of non-irritant cool mosquito-repellent wet tissue

Abstract

The invention provides a preparation method of a non-irritant cool mosquito-repellent wet tissue. The preparation method comprises the following steps: S1, selecting a spunlace non-woven fabric as a base material of the wet tissue; s2, preparing mosquito-repellent liquid which is prepared by mixing the following components in percentage by weight: 1 to 5 percent of mint extract, 1 to 5 percent of clove extract, 1 to 5 percent of bee sting extract, 1 to 5 percent of narcissus extract and the balance of water, and the mosquito-repellent liquid is prepared by mixing the following components in percentage by weight: 1 to 5 percent of mint extract, 1 to 5 percent of clove extract, 1 to 5 percent of bee sting extract, 1 to 5 percent of narcissus extract and the balance of water; s3, the base material is soaked in the mosquito repelling liquid medicine. According to the invention, natural Chinese herbal medicine extracts are adopted to prepare the mosquito-repelling liquid medicine, the mosquito-repelling liquid medicine is non-irritant to skin and suitable for long-term use, and the adopted mint extract has the effects of cooling fragrance, clearing heat and eliminating fire, and can effectively relieve skin itch; the adopted clove, bee sting and narcissus extracts have unique fragrance and mosquito repelling effect, and mosquito bites can be effectively prevented; and the spunlace non-woven fabric is adopted as a base material, and is soft in texture, breathable, good in water absorption and comfortable to use.

Description

Technical Field

[0001] The invention relates to the technical field of wet wipe preparation, and in particular to a method for preparing non-irritating, cooling and mosquito-repellent wet wipes. Background Art

[0002] With the improvement of living standards, people's demand for personal hygiene products is increasing. As a convenient and easy-to-use hygiene product, mosquito repellent wipes have been widely used in outdoor activities and daily life in summer. However, most of the existing mosquito repellent wipes contain chemical ingredients, which may cause irritation or side effects to the skin with long-term use. Therefore, it is of great significance to develop a non-irritating, cool and mosquito-repellent wet wipe.

[0003] Therefore, a method for preparing a non-irritating, refreshing and mosquito-repellent wet wipe is proposed. Summary of the invention

[0004] The present invention aims to solve the problems raised in the background technology and provides a method for preparing non-irritating, cooling and mosquito-repellent wet wipes. The wet wipes prepared by the method have the special effects of cooling, relieving itching, repelling mosquitoes and avoiding insects, and are soft in texture, non-irritating to the skin, and have no side effects after long-term use.

[0005] The specific technical solutions are as follows:

[0006] A method for preparing a non-irritating, cooling and mosquito-repellent wet wipe comprises the following steps:

[0007] S1. Select spunlace nonwoven fabric as the base material of wet wipes;

[0008] S2, preparing a mosquito repellent liquid, which is mixed with peppermint extract, clove extract, bee stinging grass extract, narcissus extract and water, and the weight percentage of each component is: peppermint extract 1%-5%, clove extract 1%-5%, bee stinging grass extract 1%-5%, narcissus extract 1%-5%, and water is the balance;

[0009] S3, dipping the base material into the mosquito repellent liquid for 10-30 minutes;

[0010] S4, drying the impregnated base material, and the humidity of the wet wipes after drying is the humidity required for use;

[0011] S5. Cut the dried base material into wet wipes of required size.

[0012] The method for preparing the non-irritating, cooling and mosquito-repellent wet wipes further comprises a step S6 of conducting quality inspection on the prepared wet wipes.

[0013] The method for preparing the non-irritating, cooling and mosquito-repellent wet wipes, wherein: the quality inspection in step S6 includes inspection of the mosquito-repellent effect and skin irritation of the wet wipes.

[0014] The preparation method of the above-mentioned non-irritating, cooling and mosquito-repellent wet wipes, wherein: the specific steps of the mosquito-repellent effect detection are as follows:

[0015] Step S610: Test preparation

[0016] Sample selection: Select a certain number of experimental animals to ensure that the sample is representative;

[0017] Mosquito repellent products: Prepare the mosquito repellent wipes to be tested, and ensure that the quantity of the product is sufficient for multiple repeated tests;

[0018] Mosquito source: obtain a sufficient number of mosquitoes, usually laboratory-cultured mosquitoes, to ensure that the activity and number of mosquitoes meet the test requirements;

[0019] Step S611: Test method

[0020] Step S6111, exposure treatment: applying mosquito repellent wipes to the exposed parts of the test animals, ensuring that the wipes are in close contact with the skin;

[0021] Step S6112, mosquito contact: within a set time period, release mosquitoes near the exposed part, and observe and record the mosquito bites;

[0022] Step S6113, data recording: recording the number of mosquito bites in different time periods, and the reactions after the bites;

[0023] Step S612: Data analysis

[0024] Calculate the mosquito repellent rate: Calculate the mosquito repellent rate of the mosquito repellent wipes according to the number of mosquito bites recorded, mosquito repellent rate = (number of bites in the control group - number of bites in the test group) / number of bites in the control group × 100%;

[0025] Statistical significance: Statistical methods were used to analyze whether the differences in mosquito repellent rates in different time periods were statistically significant;

[0026] Step S613: Conclusion

[0027] Based on the data analysis results, it can be determined whether the mosquito repellent wipes have a significant mosquito repellent effect and their stability in different time periods.

[0028] The preparation method of the above-mentioned non-irritating, cooling and mosquito-repellent wet wipes, wherein: the specific steps of the skin irritation test are as follows:

[0029] Step S620: Test preparation

[0030] Sample selection: Select a certain number of experimental animals to ensure that the sample is representative;

[0031] Test materials: Prepare the mosquito repellent wipes to be tested, and saline solution for skin cleaning;

[0032] Step S621: Test method

[0033] Step S6211, skin cleaning: before the test, the exposed parts of the test animals are thoroughly cleaned to remove factors such as grease and dirt that may affect the test results;

[0034] Step S6212, wet wipe application: apply mosquito repellent wet wipes to the exposed part, ensuring that the wet wipes are in close contact with the skin. The application time is set according to the test requirements, usually ranging from several hours to several days;

[0035] Step S6213, observation and recording: during the application period and for a period of time after the application, regularly observe and record the skin reaction of the exposed part;

[0036] Step S622: Data analysis

[0037] Skin reaction scoring: Scoring was performed using a scoring criteria based on the observed skin reactions;

[0038] Statistical significance: Statistical methods were used to analyze whether the differences in skin reaction scores in different time periods were statistically significant;

[0039] Step S623: Conclusion

[0040] Based on the data analysis results, it is determined whether the mosquito repellent wipes are irritating to the skin, as well as the degree and duration of the irritation.

[0041] The method for preparing the non-irritating, cooling and mosquito-repellent wet wipes further comprises a step S7 of packaging the cut wet wipes.

[0042] The method for preparing the above-mentioned non-irritating, cooling and mosquito-repellent wet wipes, wherein: the packaging material for the packaging treatment in step S7 is a waterproof material.

[0043] The preparation method of the above-mentioned non-irritating, cooling and mosquito-repellent wet wipes, wherein: the specific preparation method of the mosquito-repellent liquid comprises the following steps:

[0044] S21. Material preparation:

[0045] Peppermint extract, clove extract, bee sting extract, narcissus extract, water;

[0046] S22, proportion determination:

[0047] According to the weight percentage of each component, the mint extract accounts for 1%-5% of the total weight of the mosquito repellent liquid, the clove extract, the bee stinging grass extract and the narcissus extract also account for 1%-5% each, and the rest is water;

[0048] S23, Mixing and Heating:

[0049] Pour the prepared various extracts and water into a container according to the proportions;

[0050] Use a whisk or hand blender to mix the mixture well to ensure that all components are thoroughly mixed;

[0051] The mixture is heated to 50-60°C to facilitate dissolution and mixing of the extract;

[0052] S24, stirring and filtering:

[0053] Continue stirring the mixture during heating to ensure even distribution of the components;

[0054] After heating was complete, the mixture was cooled to room temperature;

[0055] Strain the mixture through a filter or strainer to remove any impurities and particles present;

[0056] S25, Quality Inspection:

[0057] Conduct quality inspection on the prepared mosquito repellent liquid to ensure that it meets the expected mosquito repellent effect and safety standards.

[0058] S26. Storage and backup:

[0059] The mosquito repellent liquid that has passed the quality inspection is stored in a container, which is sealed and placed in a cool and dry place. The prepared mosquito repellent liquid is used for the subsequent wet wipes impregnation step.

[0060] The method for preparing the above-mentioned non-irritating, cooling and mosquito-repellent wet wipes, wherein: the humidity of the wet wipes after the drying treatment in step S4 is between 50% and 60%.

[0061] The method for preparing the above-mentioned non-irritating, cooling and mosquito-repellent wet wipes, wherein: the prepared non-irritating, cooling and mosquito-repellent wet wipes are used for outdoor activities and daily use in summer.

[0062] The preparation method of the non-irritating, cooling and mosquito-repellent wet wipes provided by the present invention has the following beneficial effects:

[0063] 1. Non-irritating: The mosquito repellent liquid is prepared with natural Chinese herbal extracts, which is non-irritating to the skin and suitable for long-term use.

[0064] 2. Cooling and relieving itching: Peppermint extract has a cool aroma and the effect of clearing heat and relieving fire, which can effectively relieve skin itching.

[0065] 3. Repel mosquitoes and avoid insects: Clove, bee stinging grass and narcissus extracts have unique aroma and mosquito repellent effects, which can effectively prevent mosquito bites.

[0066] 4. Soft texture: Spunlace non-woven fabric is used as the base material, which is soft, breathable, has good water absorption and is comfortable to use. BRIEF DESCRIPTION OF THE DRAWINGS

[0067] Figure 1 The present invention provides a flowchart of a method for preparing a non-irritating, cooling and mosquito-repellent wet wipe. DETAILED DESCRIPTION

[0068] The technical solution of the present invention is further described below with reference to the accompanying drawings and through specific implementation methods.

[0069] Among them, the drawings are only used for illustrative explanations, and they only represent schematic diagrams rather than actual pictures, and should not be understood as limitations on this patent; in order to better illustrate the embodiments of the present invention, some parts of the drawings may be omitted, enlarged or reduced, and do not represent the size of the actual product; for those skilled in the art, it is understandable that some well-known structures and their descriptions in the drawings may be omitted.

[0070] The same or similar numbers in the drawings of the embodiments of the present invention correspond to the same or similar parts; in the description of the present invention, it should be understood that if the terms "upper", "lower", "left", "right", "inner", "outer", etc. appear, the orientation or position relationship indicated is based on the orientation or position relationship shown in the drawings, which is only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation. Therefore, the terms describing the position relationship in the drawings are only used for illustrative purposes and cannot be understood as a limitation on this patent. For ordinary technicians in this field, the specific meanings of the above terms can be understood according to specific circumstances.

[0071] In the description of the present invention, unless otherwise clearly specified and limited, if the term "connection" or the like appears to indicate the connection relationship between components, the term should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, it can be the internal connection of two components or the interaction relationship between two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0072] Example

[0073] The preparation method of the non-irritating, cooling and mosquito-repellent wet wipes provided in this embodiment is as follows: Figure 1 As shown, the following steps are included:

[0074] S1. Select spunlace nonwoven fabric as the base material of wet wipes. Select spunlace nonwoven fabric as the base material of wet wipes. The base material is soft, breathable and has good water absorption;

[0075] S2, preparing a mosquito repellent liquid, which is mixed with peppermint extract, clove extract, bee stinging grass extract, narcissus extract and water, and the weight percentage of each component is: peppermint extract 1%-5%, clove extract 1%-5%, bee stinging grass extract 1%-5%, narcissus extract 1%-5%, and water is the balance;

[0076] S3, immersing the base material selected in step 1 in the mosquito repellent liquid prepared in step 2, so that the base material fully absorbs the liquid. The immersion time can be adjusted according to actual needs, generally 10-30 minutes;

[0077] S4. Dry the impregnated base material to remove excess liquid medicine so that the wet wipes reach an appropriate humidity, such as

[0078] S5, cutting the dried base material into wet wipes of required size;

[0079] Step S6, performing quality inspection on the prepared wet wipes, including inspection on mosquito repellent effect and skin irritation of the wet wipes;

[0080] Step S7 is to package the wet wipes that have been cut and tested to be qualified for carrying and use, and the packaging material for the packaging process is a waterproof material, such as a plastic bag.

[0081] Among them, the specific steps of mosquito repellent effect detection are as follows:

[0082] Step S610: Test preparation

[0083] Sample selection: Select a certain number of experimental animals (such as mice) to ensure that the sample is representative;

[0084] Mosquito repellent products: Prepare the mosquito repellent wipes to be tested, and ensure that the quantity of the product is sufficient for multiple repeated tests;

[0085] Mosquito source: obtain a sufficient number of mosquitoes, usually laboratory-cultured mosquitoes, such as Aedes aegypti or Aedes albopictus, to ensure that the activity and number of mosquitoes meet the test requirements;

[0086] Step S611: Test method

[0087] Step S6111, exposure treatment: apply mosquito repellent wipes to the exposed parts (such as legs) of the test animals, ensuring that the wipes are in close contact with the skin;

[0088] Step S6112, mosquito contact: within a set time period, release mosquitoes near the exposed part, and observe and record the mosquito bites;

[0089] Step S6113, data recording: recording the number of mosquito bites in different time periods, and the reactions after the bites (such as redness, swelling, itching, etc.);

[0090] Step S612: Data analysis

[0091] Calculate the mosquito repellent rate: Calculate the mosquito repellent rate of the mosquito repellent wipes according to the number of mosquito bites recorded, mosquito repellent rate = (number of bites in the control group - number of bites in the test group) / number of bites in the control group × 100%;

[0092] Statistical significance: Use appropriate statistical methods (such as t-test, chi-square test, etc.) to analyze whether the differences in mosquito repellent rates in different time periods are statistically significant;

[0093] Step S613: Conclusion

[0094] Based on the data analysis results, it can be determined whether the mosquito repellent wipes have a significant mosquito repellent effect and their stability in different time periods.

[0095] Among them, the mosquito repellent effect test data are as follows:

[0096] Experimental conditions: Number of mice: 30; Mosquito species: Aedes aegypti; Exposure time: 4 hours; Number of repetitions: 3 times.

[0097] Experimental data:

[0098]

[0099] Data analysis: In the three experiments, the average number of bites in the control group was 12, 10 and 14, and the average number of bites in the experimental group was 3, 2 and 4; according to the calculation formula of the mosquito repellent rate, the mosquito repellent rates of the three experiments were 75%, 80% and 71.4% respectively. The mosquito repellent rates remained at a high level in the three experiments with little difference, indicating that the mosquito repellent effect of the mosquito repellent wipes is stable and significant.

[0100] The specific steps of skin irritation testing are as follows:

[0101] Step S620: Test preparation

[0102] Sample selection: Select a certain number of experimental animals (such as mice) to ensure that the sample is representative;

[0103] Test materials: Prepare mosquito repellent wipes to be tested, as well as saline solution for skin cleaning, etc.;

[0104] Step S621: Test method

[0105] Step S6211, skin cleaning: before the test, the exposed parts (such as legs) of the test animals (such as mice) are thoroughly cleaned to remove factors such as grease and dirt that may affect the test results;

[0106] Step S6212, wet wipe application: apply mosquito repellent wet wipes to the exposed part, ensuring that the wet wipes are in close contact with the skin. The application time can be set according to the test requirements, usually ranging from several hours to several days;

[0107] Step S6213, observation and recording: during the application period and for a period of time after the application, regularly observe and record the skin reactions of the exposed parts, such as redness, swelling, itching, pain, blisters, etc.;

[0108] Step S622: Data analysis

[0109] Skin reaction scoring: Based on the observed skin reactions, appropriate scoring criteria (such as skin irritation scoring criteria) are used for scoring;

[0110] Statistical significance: Appropriate statistical methods were also used to analyze whether the differences in skin reaction scores in different time periods were statistically significant;

[0111] Step S623: Conclusion

[0112] Based on the data analysis results, it is determined whether the mosquito repellent wipes are irritating to the skin, as well as the degree and duration of the irritation.

[0113] Skin irritation test data

[0114] Experimental conditions: Number of mice: 20; Application time: 24 hours; Observation time: 72 hours after application; Number of repetitions: 2 times.

[0115] Experimental data:

[0116] Number of experiments Skin reaction score (average per mouse) Irritation determination 1 0.5 Non-irritating 2 0.3 Non-irritating

[0117] Skin irritation rating criteria:

[0118] 0: no reaction; 1: mild erythema; 2: obvious erythema, possibly accompanied by mild edema; 3: severe erythema, accompanied by obvious edema; 4: severe erythema, accompanied by blisters or ulcers.

[0119] Data Analysis:

[0120] In the two experiments, the average skin reaction scores of mice were 0.5 and 0.3 respectively, both below 1 point. According to the skin irritation scoring standard, both experiments were judged to be non-irritating. The results of the two experiments were consistent, indicating that the mosquito repellent wipes are non-irritating to the skin.

[0121] It is worth noting that when conducting mosquito repellent effect and skin irritation tests, the ethics and safety of the tests should be ensured, and relevant test specifications and guidelines should be followed.

[0122] During the test, the test conditions, such as temperature, humidity, light, etc., should be strictly controlled to reduce the impact of external factors on the test results.

[0123] The test results should be verified repeatedly to ensure their reliability and accuracy.

[0124] Through the above-mentioned testing scheme, the mosquito repellent effect and skin irritation of mosquito repellent wipes can be comprehensively evaluated, providing a scientific basis for the safety and effectiveness of the product.

[0125] The specific preparation method of the mosquito repellent liquid comprises the following steps:

[0126] S21. Material preparation:

[0127] Peppermint Extract: Choose a peppermint extract with high purity to ensure its cooling effect and aroma.

[0128] Clove Extract: Clove has a unique aroma and mosquito repellent effect, choose the appropriate extract concentration.

[0129] Bee stinging grass extract: Bee stinging grass is also an effective mosquito repellent plant, and its extract also has a mosquito repellent effect.

[0130] Narcissus extract: The aromatic ingredients of narcissus can also help repel mosquitoes. Choose the appropriate extract for use.

[0131] Water: As a solvent, used to dissolve and mix the above extracts.

[0132] S22, proportion determination:

[0133] The specific amount of each extract is determined according to the weight percentage of each component. For example, peppermint extract accounts for 1%-5% of the total weight of the mosquito repellent liquid, clove extract, bee stinging grass extract and narcissus extract also account for 1%-5% each, and the rest is water.

[0134] S23, mixing and heating:

[0135] Pour the prepared extracts and water into a suitable container according to the proportions.

[0136] Use a whisk or hand blender to stir the mixture well to ensure that all ingredients are thoroughly combined.

[0137] The mixture is heated to an appropriate temperature (eg, 50-60°C) to facilitate dissolution and mixing of the extract.

[0138] S24, stirring and filtering:

[0139] The mixture was stirred continuously during heating to ensure even distribution of the components.

[0140] After heating was complete, the mixture was cooled to room temperature.

[0141] Strain the mixture through a strainer or mesh to remove any impurities and particles that may be present.

[0142] S25, Quality Inspection:

[0143] Conduct quality inspection on the prepared mosquito repellent liquid to ensure that it meets the expected mosquito repellent effect and safety standards.

[0144] Laboratory tests can be used to evaluate the performance of the liquid in terms of mosquito repellency, skin irritation, etc.

[0145] S26. Storage and backup:

[0146] Store mosquito repellent liquid that has passed quality inspection in appropriate containers, seal them and place them in a cool and dry place.

[0147] The prepared mosquito repellent liquid can be used in the subsequent wet wipes impregnation step.

[0148] Through the above steps, a mosquito repellent liquid with cooling, antipruritic, mosquito repellent and insect repellent effects can be prepared. The liquid is combined with a soft, breathable and well-absorbent spunlace non-woven fabric to make a non-irritating, cooling mosquito repellent wet wipe.

[0149] In summary, the preparation method of the non-irritating, cooling and mosquito-repellent wet wipes provided in this embodiment has the following advantages:

[0150] 1. Non-irritating: The mosquito repellent liquid is prepared with natural Chinese herbal extracts, which is non-irritating to the skin and suitable for long-term use.

[0151] 2. Cooling and relieving itching: Peppermint extract has a cool aroma and the effect of clearing heat and relieving fire, which can effectively relieve skin itching.

[0152] 3. Repel mosquitoes and avoid insects: Clove, bee stinging grass and narcissus extracts have unique aroma and mosquito repellent effects, which can effectively prevent mosquito bites.

[0153] 4. Soft texture: Spunlace non-woven fabric is used as the base material, which is soft, breathable and has good water absorption. It is comfortable to use. The non-irritating, cool and mosquito repellent wipes prepared are especially suitable for outdoor activities and daily use in summer.

[0154] The above are only preferred embodiments of the present invention, and are not intended to limit the implementation methods and protection scope of the present invention. Those skilled in the art should be aware that all solutions obtained by equivalent substitutions and obvious changes made using the description and illustrations of the present invention should be included in the protection scope of the present invention.

Claims

1. A method for preparing a non-irritating, cooling and mosquito-repellent wet wipe, characterized in that: The following steps are involved: S1. Select spunlace nonwoven fabric as the base material of wet wipes; S2, preparing a mosquito repellent liquid, which is mixed with peppermint extract, clove extract, bee stinging grass extract, narcissus extract and water, and the weight percentage of each component is: peppermint extract 1%-5%, clove extract 1%-5%, bee stinging grass extract 1%-5%, narcissus extract 1%-5%, and water is the balance; S3, dipping the base material into the mosquito repellent liquid for 10-30 minutes; S4, drying the impregnated base material, and the humidity of the wet wipes after drying is the humidity required for use; S5. Cut the dried base material into wet wipes of required size.

2. The method for preparing the non-irritating, cooling and mosquito-repellent wet wipes according to claim 1, characterized in that: The method also includes step S6 of performing quality inspection on the prepared wet wipes.

3. The method for preparing the non-irritating, cooling and mosquito-repellent wet wipes according to claim 2, characterized in that: The quality inspection in step S6 includes inspection of the mosquito repellent effect and skin irritation of the wet wipes.

4. The method for preparing the non-irritating, cooling and mosquito-repellent wet wipes according to claim 3, characterized in that: The specific steps of the mosquito repellent effect detection are as follows: Step S610: Test preparation Sample selection: Select a certain number of experimental animals to ensure that the sample is representative; Mosquito repellent products: Prepare the mosquito repellent wipes to be tested, and ensure that the quantity of the product is sufficient for multiple repeated tests; Source of mosquitoes: obtain a sufficient number of mosquitoes and select mosquitoes cultured in the laboratory to ensure that the activity and number of mosquitoes meet the test requirements; Step S611: Test method Step S6111, exposure treatment: applying mosquito repellent wipes to the exposed parts of the test animals, ensuring that the wipes are in close contact with the skin; Step S6112, mosquito contact: within a set time period, release mosquitoes near the exposed part, and observe and record the mosquito bites; Step S6113, data recording: recording the number of mosquito bites in different time periods, and the reactions after the bites; Step S612: Data analysis Calculate the mosquito repellent rate: Calculate the mosquito repellent rate of the mosquito repellent wipes according to the number of mosquito bites recorded, mosquito repellent rate = (number of bites in the control group - number of bites in the test group) / number of bites in the control group × 100%; Statistical significance: Statistical methods were used to analyze whether the differences in mosquito repellent rates in different time periods were statistically significant; Step S613: Conclusion Based on the data analysis results, it can be determined whether the mosquito repellent wipes have a significant mosquito repellent effect and their stability in different time periods.

5. The method for preparing the non-irritating, cooling and mosquito-repellent wet wipes according to claim 3, characterized in that: The specific steps of the skin irritation test are as follows: Step S620: Test preparation Sample selection: Select a certain number of experimental animals to ensure that the sample is representative; Test materials: Prepare the mosquito repellent wipes to be tested, and saline solution for skin cleaning; Step S621: Test method Step S6211, skin cleaning: before the test, the exposed parts of the test animals are thoroughly cleaned to remove factors such as grease and dirt that may affect the test results; Step S6212, wet wipes application: apply mosquito repellent wet wipes to the exposed parts, ensure that the wet wipes are in close contact with the skin, and set the application time according to the test requirements; Step S6213, observation and recording: during the application period and for a period of time after the application, regularly observe and record the skin reaction of the exposed part; Step S622: Data analysis Skin reaction scoring: Scoring was performed using a scoring criteria based on the observed skin reactions; Statistical significance: Statistical methods were used to analyze whether the differences in skin reaction scores in different time periods were statistically significant; Step S623: Conclusion Based on the data analysis results, it is determined whether the mosquito repellent wipes are irritating to the skin, as well as the degree and duration of the irritation.

6. The method for preparing the non-irritating, cooling and mosquito-repellent wet wipes according to claim 2, characterized in that: The method further includes step S7 of packaging the cut wet wipes.

7. The method for preparing the non-irritating, cooling and mosquito-repellent wet wipes according to claim 4, characterized in that: The packaging material in the packaging process in step S7 is a waterproof material.

8. The method for preparing the non-irritating, cooling and mosquito-repellent wet wipes according to claim 1, characterized in that: The specific preparation method of the mosquito repellent liquid comprises the following steps: S21. Material preparation: Peppermint extract, clove extract, bee sting extract, narcissus extract, water; S22, proportion determination: According to the weight percentage of each component, the mint extract accounts for 1%-5% of the total weight of the mosquito repellent liquid, the clove extract, the bee stinging grass extract and the narcissus extract also account for 1%-5% each, and the rest is water; S23, Mixing and Heating: Pour the prepared various extracts and water into a container according to the proportions; Use a whisk or hand blender to mix the mixture well to ensure that all components are thoroughly mixed; The mixture is heated to 50-60°C to facilitate dissolution and mixing of the extract; S24, stirring and filtering: Continue stirring the mixture during heating to ensure even distribution of the components; After heating was complete, the mixture was cooled to room temperature; Strain the mixture through a filter or strainer to remove any impurities and particles present; S25, Quality Inspection: Conduct quality inspection on the prepared mosquito repellent liquid to ensure that it meets the expected mosquito repellent effect and safety standards; S26. Storage and backup: The mosquito repellent liquid that has passed the quality inspection is stored in a container, which is sealed and placed in a cool and dry place. The prepared mosquito repellent liquid is used for the subsequent wet wipes impregnation step.

9. The method for preparing the non-irritating, cooling and mosquito-repellent wet wipes according to claim 1, characterized in that: The humidity of the wet wipes after the drying process in step S4 is between 50% and 60%.

10. The method for preparing the non-irritating, cooling and mosquito-repellent wet wipes according to any one of claims 1 to 9, characterized in that: The prepared non-irritating, refreshing and mosquito-repellent wet wipes are used for outdoor activities and daily use in summer.

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