Method and device for measuring autonomic nerve heart regulation and control function

Abstract

The invention relates to a method and device for measuring the autonomic nerve heart regulation and control function. The wearable device, an autonomic nerve heart regulation and control function mathematical model and an autonomic nerve heart regulation and control system parameter calculation method are involved in the method. The wearable device is used for measuring motion data, continuous blood pressure and a heart rate value sequence in a human body standing-up or inclining test. The autonomic nerve heart regulation and control function mathematical model is used for quantitatively describing the blood pressure and heart rate regulation and control process in the standing-up process. According to the autonomic nerve heart regulation and control system parameter calculation method, a series of autonomic nerve heart regulation and control system parameters such as pressure sensor sensitivity and sympathetic nerve and parasympathetic nerve activity are solved based on the autonomic nerve heart regulation and control function mathematical model and the continuous blood pressure and the heart rate value sequence measured in the standing-up or inclining test through the wearable device. Autonomic nerve regulation and control disorders are represented by reduction of the pressure sensor sensitivity and reduction of the sympathetic nerve and parasympathetic nerve activity, which are the occurrence origins and independent indexes of many lethal cardiovascular diseases. Quantitative measurement of the pressure sensor sensitivity and the sympathetic nerve and parasympathetic nerve activity is of great significance on effective diagnosis and prevention of cardiovascular diseases, evaluation of treatment effects and recovery of patients.

Description

technical field [0001] The invention belongs to the technical field of medical detection, and in particular relates to a method and equipment for measuring autonomic nerve heart regulation function. Background technique [0002] According to the "China Cardiovascular Disease Report 2012", there are 290 million patients with cardiovascular disease nationwide, including 266 million with hypertension (24% prevalence), at least 7 million with stroke, 2.5 million with myocardial infarction, and 4.5 million with heart failure. Hypertension is the main risk factor for stroke and coronary heart disease. More than half of the cardiovascular diseases in my country are related to hypertension. [0003] Modern medicine can already detect heart defects, vascular stenosis, and blood components, but there is no cardiovascular system function measurement and evaluation technology. The symptoms of many cardiovascular diseases, such as coronary heart disease, will not appear until the late...

AI Technical Summary

Problems solved by technology

However, these methods cannot obtain stable results: the first reason is that during the breathing cycle, blood pressure and heart rate are affected by breathing, but the factors affecting blood pressure and heart rate are complex, and it is difficult to attribute it to the effect of baroreceptors; reason two, It is unscientific to define baroreceptor sensitivity as the change in heart rate caused by unit blood pressure changes, because baroreceptors sense pressure changes, output excitation impulses to sympathetic and parasympathetic nerves, and cannot produce heart rate changes by themselves

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