13 results about "Cervical tissue" patented technology

The present invention proposes a device (100) for collecting cervical tissue samples, comprising: a sample collecting bud (10) connecting to one end of an elongated shaft (21); a holder (20) provided at the other end of the elongated shaft (21); a handle (30) enclosing the elongated shaft (21), wherein the elongated shaft (21) is slidable and rotatable within the handle (30); characterized in that: the sample collecting bud (10) is retractable into the handle (30) and extendable from the handle (30) by moving the holder (20) connected to the sample collecting bud (10) via the elongated shaft (21); wherein the sample collecting bud (10) comprises a star-shaped center cone (11) having a flat tip end, and a plurality of petal-like structures (12) surrounding the center cone (11), each of the petal-like structure (12) having an inner scraping ridge (13) and an outer scraping ridge (14).

The utility model relates to medical instrument technical field discloses a kind of noninvasive cervical cerclage buckles, including flexible kit, one end of flexible kit is provided with upper connecting ring, the other end is provided with lower connecting ring, upper connecting ring inside is provided with the upper annular passage for accommodating first connecting buckle, one end of first connecting buckle enters from the side import of upper annular passage, and it is passed out from the other side export of upper annular passage by the inside of upper annular passage.The utility model is fixed on cervix by setting upper connecting ring and lower connecting ring on the upper and lower ends of flexible kit, and setting the first, second connecting buckle that can be tightened on upper and lower connecting ring, reach the purpose of bundling.Compared with cervical cerclage, it has the superiority of noninvasive, fast, without anesthesia, compared with the cervical support product on market, can provide high-quality individualized product for patient, release the compression to vaginal wall and pelvic tissue, effectively avoid the irritation and harm of operation to cervical tissue.

Aspects described herein may include a method of diagnosing cervical cancer and pre-cancer conditions, including: utilizing a computer to extract a numerical value corresponding to an order parameter squared (S2) from image data from at least one image of cervical tissue / cells from a patient, wherein the image data includes at least one region having light regions and dark regions, and wherein S2 includes a numerical value quantifying a degree of order present in the image data, and wherein the extracted numerical value comprises a ratio of an area of the light regions to a total area; comparing the extracted numerical value to one or more predefined diagnosis ranges corresponding to stages of cervical cancer and pre-cancer conditions; and diagnosing the stage of the cervical cancer and pre-cancer conditions if the numerical value of the S2 falls within one of the predefined diagnosis ranges.

The invention relates to the technical field of hysteroscopes, and discloses a disposable hysteroscope which comprises a grab handle, a mirror rod is arranged on the grab handle, and a guide head is arranged at the end of the mirror rod; the guide head comprises an abduction lip part and a convergent neck part, a guide hole is formed in the center of the abduction lip part, the mirror rod penetrates through the guide hole, the convergent neck part is arranged on the mirror rod in a sleeving mode, the abduction lip part is in a horn shape, the narrow end of the abduction lip part is connected with the convergent neck part, and the convergent neck part makes friction contact with the mirror rod; the mirror rod is close to the guide hole, so that the open end of the abduction lip part is enlarged. According to the disposable hysteroscope, accurate centering of the disposable hysteroscope and a cervical opening can be automatically completed. When the abduction lip is in contact with the cervix uteri, the elastic petal structure can automatically adjust the angle under the interaction of the propulsive force of the mirror rod and the counter-acting force of the cervix uteri tissue until the center of the guide hole coincides with the center of the cervix uteri opening.

The invention relates to an early diagnosis reagent for cervical and gastric adenocarcinoma based on multi-marker combination and application thereof, PGC can be used as a new marker for detecting cervical and gastric adenocarcinoma, and PGC is not expressed in other cervical adenocarcinoma and tumors except cervical and gastric adenocarcinoma and normal cervical tissues, and has extremely high specificity; furthermore, the PGC can be combined with the CLDN18.2 and the HIK1083, so that the positive predicted value can be obviously improved.

The invention provides a cervical cancer prognosis evaluation kit based on ITM2A mRNA expression level and application of the cervical cancer prognosis evaluation kit, and belongs to the technical field of molecular detection. The kit disclosed by the invention comprises a primer pair capable of specifically amplifying a human ITM2A gene sequence; through detection of expression levels of ITM2A genes and encoded proteins in normal cervical tissues and tumor tissues, it is found that expression of ITM2A in the tumor tissues of cervical cancer patients is remarkably reduced, and a kit for prognosis judgment of cervical cancer is developed based on the discovery. The method has extremely important significance on risk assessment and prognosis prediction of cervical cancer patients.

This invention belongs to the field of biomedical technology, specifically relating to a tumor-suppressive *Escherichia coli* 18 and its uses, and more specifically to *Escherichia coli* HZ_Ec_18 and its applications. This invention obtains multiple strains with potential to influence the tumor microenvironment through in vitro culture and purification of bacteria from cervical tissue and vaginal swabs of cervical cancer patients. Among them, *Escherichia coli* HZ_Ec_18 exhibits stronger tumor cell inhibitory activity and interaction with host cells, and can be used for the development of anti-tumor drugs.

This invention relates to the field of photoelectric probes, specifically a multi-point photoelectric probe for cervical cancer screening instruments. It includes a probe body and a detector handle. The probe body adopts a slender, hollow tubular structure, serving as the support and wiring main body for the probe, and internally housing multiple independent optical fibers. An end-face detection section, located at the very front of the probe, is elliptical in shape and is a dedicated cervical tissue detection component. A ring-shaped detection section, fitted onto the ring-shaped side of the probe body behind the end-face detection section, is a dedicated vaginal wall tissue detection component. An adjustment section is used to adjust the orientation of the end-face detection section, expanding the detection range and ensuring that all areas of the cervix can be effectively detected. The front end of the probe body is fixedly connected to the end-face detection head, and the rear end is detachably connected to the detector handle. This multi-point photoelectric probe for cervical cancer screening instruments, through its separate dedicated design of the end-face and ring-shaped detection heads, achieves for the first time simultaneous screening of both the cervix and vaginal wall areas with a single probe insertion.

The utility model discloses a kind of for cervical conization specimen's split piece device, it is related to pathological analysis technical field, including base, the position of the outside of base near upper side is threadedly connected with threaded sleeve, the upper side of threaded sleeve is rotatably connected with cutting mechanism, the outside of cutting mechanism is movably sleeved with fixed mechanism, the upper side middle part of base is movably installed with electric push rod, the cutting mechanism includes mechanism pipe, the upper side of mechanism pipe is fixedly connected with conical seat, the lower side of mechanism pipe is rotatably connected in the upper side of threaded sleeve, the upper side of electric push rod is fixedly connected with fixed rod.The utility model said a kind of for cervical conization specimen's split piece device, directly drive blade to go up by electric push rod, so that blade carries out cutting to cervical tissue, electric push makes it unnecessary to manually provide greater pressure to push blade, while electric push rod can hide blade in mechanism pipe, more safe.

The utility model relates to the field of surgical suture needles and threads, and discloses a needle and thread assembly based on cervical cerclage surgical suture, which comprises a suture line and a suture needle, the cross section of the suture line is circular, the suture line comprises a main line section, and two ends of the main line section are respectively connected with a transition section. The diameter of the transition section is gradually reduced along the extension direction; the large-diameter end of the transition section is connected with the main line section; the small-diameter end of the transition section is connected with the needle threading section; according to the scheme, the main line section serves as a main body of the suture line, the diameter of the main line section is relatively large, the section of the main line section is round, and the problem that due to the fact that the suture line is thin, tension is large, and cutting wounds of the thin line to cervical tissue are likely to happen can be solved, and particularly under the condition that suture and binding retention time is long, the thin line is likely to damage the tissue and cause infection; the needle threading section is used for being connected with a suture needle, the diameter of the needle threading section is relatively small, the needle threading section can more conveniently penetrate into a needle eye of the suture needle, and compared with a thick thread, the thin thread is easier to knot.

The application discloses a kind of long-term treatment strategy making methods for cervical cancer prevention and treatment of HPV, belong to medical information processing technical field.The method includes: obtaining the digital HPV health record containing multiple HPV typing detection results, cervical cytology history record and individual physiological characteristic parameters;Three-dimensional treatment situation cube is constructed by virus infection state subspace, cervical tissue state subspace and treatment intervention state subspace;In the cube, state backtracking and forward-looking deduction algorithm based on time axis are used, virus clearance probability field and lesion outcome probability field are calculated;High-risk persistent infection space-time region and low-risk self-healing tendency space-time region are demarcated;Current patient state is projected to the cube, if fall into high-risk region, then trigger long-term treatment strategy generation process including multiple treatment stages, output intervention opportunity, intensity and state transition condition of each stage.

The invention relates to the technical field of image processing, in particular to a cervical pathology multi-mode slice image recognition method and system. Comprising the following steps: acquiring two different staining section images of the same cervical tissue sample, respectively performing semantic structure recognition to extract biological structure types and geometric positions thereof, and generating two groups of feature point sets with structure type labels according to the biological structure types and the geometric positions thereof; respectively analyzing the spatial relationship between the feature points to construct topological descriptions, and determining the corresponding matching of the cross-modal feature points by combining the two groups of topological descriptions under the constraint of the consistency of the structure types; sparse deformation information is calculated through the matching point pairs, a dense deformation field representing mapping from the second image to the first image is generated through interpolation, a fine deformation field is obtained through further iterative optimization, and geometric transformation is conducted on the second slice image to achieve alignment with the first slice image. The technical problem of fusion analysis errors caused by difficulty in accurate alignment of multi-modal slice images due to tissue deformation in a pathological slice preparation process is solved.

A system for providing information for diagnosing preterm birth risk includes: two or more transmit electrodes, contacting cervical tissues, for applying a plurality of first signals at different frequencies to the cervical tissues, two or more detect electrodes, contacting the cervical tissues, for detecting a plurality of second signals generated in response to the first signals, the second signals corresponding to the first signals, and a source configured to generate a plurality of signals. The system obtains a plurality of impedances of the cervical tissues based on the first and the second signals and applies data quality requirements for diagnosing the preterm birth risk. The data quality requirements include checking at least one of signal generation, signal reception, impedance calculation, quality of the first signals, quality of the second signals, and the impedances. The system includes a diagnosis engine configured to receive data including impedances that satisfy the data quality requirements, classify the data into different groups, each representing different status, based on correlation between the data, patient's information and the preterm birth risk, and output information for diagnosing the preterm birth risk.