155 results about "TURMERIC OIL" patented technology

The invention provides traditional Chinese medicine for treating breast diseases, which is formed by mixing Chinese angelica, red paeony root, peach kernels, red flower, salvia miltiorrhiza, zedoary turmeric oil, rhizoma corydalis, szechuan lovage rhizome, lumbricus, pangolin scales, uniflower swisscentaury root, fritillaria thunbergii, spina gleditsiae, cowherb seeds, angelica root, mongolian snakegourd root, concha ostreae, pericarpium citri reticulatae viride, nutgrass galingale rhizome, tangerine seeds, radix bupleuri, dandelion, rhizoma pleionis, fructus forsythiae, astragalus root, codonopsis pilosula, liquorice, frankincense, myrrh, poria cocos and oldenlandia diffusa. The traditional Chinese medicine has the effects of invigorating Qi and enriching the blood, invigorating the blood circulation and softening the hard lumps, activating the meridians and detoxicating, soothing the depressed livers and regulating the flow of Qi, softening and resolving the hard lumps, invigorating the spleens and reducing the phlegm, strengthening the healthy energy and eliminating the pathogenic factors and can be used for treating hyperplasia of mammary gland, acute or chronic mastitis, breast fibroadenoma, intraductal papilloma, breast lump, breast scrofula, breast carbuncle and breast cancer.

Disclosed herein are mixtures of turmeric extract oils. One mixture of turmeric oils is the hexane soluble fraction obtained by dissolving turmeric powder in hexane to form a hexane mixture, filtering the hexane mixture and evaporating the hexane from the turmeric oil mixture. A more refined turmeric oil combination is the oil left after the turmeric oil mixture is dissolved in hexane, placed on a silica gel / hexane chromatography column, and eluted with hexane into fractions that were then evaporated, thereby leaving the refined turmeric oil combination. Also disclosed are methods for treating inflammation, arthritis and rheumatoid arthritis and a pharmaceutical dosage form of the refined turmeric oil combination.

The invention relates to a method for extracting refined curcumin and curcuma oil from curcuma. The method comprises the following steps: the curcuma is cleaned, dried in the shade, crushed into 30-40 mesh curcuma powder, low-carbon alcohol and alkyl hydrocarbon are made into a mixed solvent at the volume ratio of 1:1-3, the curcuma powder and the mixed solvent are mixed at a weight ratio of 1:3-5 for extraction twice; the extracts are merged, filtered, separated and removed from dregs, the obtained filtrate is condensed, the concentration level is controlled at 60-90%, and the solvent is recovered; a separating agent containing 0-3% salt is added to the residual concentrated solution, the addition amount of the separating agent is 0.5-2 times of the volume of the concentrated solution, the obtained mixture is kept standing for demixing after evenly stirred; a supernatant is separated and condensed, and the alkyl hydrocarbon is recovered to obtain the curcuma oil; a subnatant is adsorbed by a macroporous absorbent resin, flushed to remove water soluble impurities, and eluted with a desorbent, the solvent is condensed and recovered to crystallize the curcumin, thus obtaining the curcumin with the content more than 95%.

The invention relates to the pharmaceutical application of a medicament combination containing oil of zedoary turmeric. The medicament combination has new pharmaceutical application for preventing and treating various diseases, such as various HPV virus subtype infections, intraepithelial lesion(isl), papilloma and cervical carcinoma, and the like, in particular to high-risk HPV subtype infections. The medicament is prepared into various conventional formulations in the category of pharmaceutics, and the medicament combination can significantly prevent and treat multiple related diseases of HPV infection by clinical verification.

The invention discloses a hydroxypropyl-beta-cyclodextrin inclusion liposome of zedoary turmeric oil and a preparation method thereof. The liposome is prepared by the following steps of: preparing a hydroxypropyl-beta-cyclodextrin inclusion of the zedoary turmeric oil from the zedoary turmeric oil and hydroxypropyl-beta-cyclodextrin through an inclusion process; and preparing the hydroxypropyl-beta-cyclodextrin inclusion liposome of the zedoary turmeric oil from the hydroxypropyl-beta-cyclodextrin inclusion, phospholipid and cholesterol through an ethanol injection method. Experimental results show that: the hydroxypropyl-beta-cyclodextrin inclusion liposome of the zedoary turmeric oil has the advantages of good sustained release and long action, high loading rate, particularly no untoward effect such as hemolysis, and higher safety.

The present invention discloses a HPLC analysis method of zedoary turmeric oil and the preparation thereof. The HPLC analysis method of the present invention can be used in the assay determination on separating the compositions of the zedoary turmeric oil extracted with various preparation techniques (supercritical CO2 liquid extraction, vapor distillation, organic solvent extraction, and so on); can be used in the assay determination on separating the compositions of the zedoary turmeric oil in various preparations made of the zedoary turmeric oil; can be used in the monitoring during the zedoary turmeric oil preparing process and the monitoring of the middle sample of the zedoary turmeric oil preparation; and can be used in the examination of the matters concerned in the zedoary turmeric oil and the study of the preparation fingerprint spectrum. The HPLC analysis method of the present invention is simple and quick, has high sensitivity and excellent repeatability, and can reflect the main compositions of the zedoary turmeric oil exactly and really.

Disclosed herein are mixtures of turmeric extract oils. One mixture of turmeric oils is the hexane soluble fraction obtained by dissolving turmeric powder in hexane to form a hexane mixture, filtering the hexane mixture and evaporating the hexane from the turmeric oil mixture. A more refined turmeric oil combination is the oil left after the turmeric oil mixture is dissolved in hexane, placed on a silica gel / hexane chromatography column, and eluted with hexane into fractions that were then evaporated, thereby leaving the refined turmeric oil combination. Also disclosed are methods for treating inflammation, arthritis and rheumatoid arthritis and a pharmaceutical dosage form of the refined turmeric oil combination.

The invention discloses a method for extracting and separating curcumin and curcuma oil from carcuma longa, which comprises the following steps of: grinding the carcuma longa into carcuma longa powder with particle size of 80-100 meshes; taking ethanol water solution as extractant for dynamic countercurrent extraction of the carcuma longa powder to obtain extraction solution, and concentrating to obtain concentrated solution; and adding the concentrated solution with plant oil extraction solvent for liquid-liquid extraction to obtain light phase containing curcuma oil and heavy phase containing curcumin. Compared with the prior art, the invention takes the ethanol water solution as the extractant and extracts the curcumin and the curcuma oil from the carcuma longa by employing the dynamic countercurrent extraction method, and the method has the advantages of simple operation, moderate extraction condition, low usage amount of solvent, short extraction time, few impurities in extraction solution and high extraction efficiency.

The invention relates to a zedoary turmeric oil adhesive membrane for external application, which comprises a backing layer and a drug membrane adhered to the backing layer. The drug membrane is prepared by the following steps that: chitosan and an acetic acid solution with the mass fraction of between 0.5 and 5 percent are mixed to prepare a 15 to 25 mg / ml chitosan solution, then the chitosan solution is mixed evenly with a 30 and 40 mg / ml polyvinyl alcohol water solution to obtain a mixed solution, the mass ratio of the chitosan and polyvinyl alcohol is 1: 0.2-1: 5, then glycerol and zedoary turmeric oil are added into the mixed solution, a surfactant is added into the mixed solution, the mixed solution is stirred for 5 to 35 min and is kept stand for defoaming, the membrane spreading is performed, and the drug membrane can be obtained by drying in a baking oven with a temperature of between 20 and 45 DEG C. The adhesive membrane has good sustained control function; the adhesive membrane can be directly pasted on afflicted parts and play a role in positioning; and the adhesive membrane improves the effective concentration of medicaments and prolongs the acting time of the medicaments, improves the bioavailability, furthest reduces the toxic side effect at the same time, and can well play clinical roles of the zedoary turmeric oil in antitumor, skin disease treatment and the like.

The present invention is medicine with antiphlogistic, analgetic, microbiostatic and diuretic effects. The present invention is prepared with turmeric, phellodendron bark, cape jasmine and puncture vine. The preparation process includes crushing turmeric and distillation to obtain volatile turmeric oil; filtering the residual liquid to obtain extract liquid; reflux extracting phellodendron bark with water or alcohol to obtain filtrate; crushing cape jasmine and puncture vine, adding turmeric slag, decocting, merging filtrate, adding extracted turmeric liquid, concentration, filtering, vacuum drying to obtain dry extractum; adding volatile turmeric oil and supplementary material to obtain oral liquid. The present invention provides the patient with more medicine selection.

The invention relates to a curcuma zedoary oil extract, as well as a preparation method, a detection method and application thereof, in particular to a method for preparing the curcuma zedoary oil extract by use of CO2 supercritical extraction. Curcuma zedoary oil provided by the invention is stable and controllable in quality, free from irritation, basically contains no curzerene, complete in effective component extraction and simple to prepare. The invention provides the application of the curcuma zedoary oil in anticarcinogen preparation.

The invention discloses an external spraying agent and / or eye drop of compound oil nano-emulsion as well as preparation method thereof. The pH value of the spraying agent and / or eye drop is 3-9. The spraying agent and / or eye drop comprise the following components according to the weight portion: 5-15 of compound oil, 0.5-2.0 of phospholipid, 0.5-3.0 of propanetriol, sodium hydroxide and medicinal water, wherein the compound oil comprises the following components: (1) zedoary turmeric oil and / or peppermint oil, and (2) soybean oil and / or castor oil. The mass ratio of the (1) and the (2) in the compound oil is 1:99-30:70. The spraying agent of the compound oil nano-emulsion, which is prepared by the invention, is used for antibiosis, inflammation diminishing and wound healing in the process of curing burn and scald. The eye drop of the compound oil nano-emulsion is used for curing eye strain, xerophthalmia and eye inflammation.

The invention relates to a method for extracting and separating turmeric oil, which comprises the step of extracting the turmeric oil from curcumas by using supercritical CO2, and is characterized in that the method also comprises the following steps: adopting first-step molecular distillation to separate curcumin and grease in the turmeric oil obtained by using the supercritical CO2 method; obtaining almost colorless turmeric essential oil under the conditions of operating pressure of 10 to 20Pa, distillation temperature of 70 to 90 DEG C, the rotation speed of a blade applicator of 200 to 300r / min and distillates of more than 75.0 percent. Adopting supercritical CO2 extraction and two-level molecular distillation, the method can effectively keep the natural ingredients of the turmeric oil, without bringing any pollution to the environment. In addition, the method also realizes the separation of oxygenous sesquiterpene from sesquiterpene in the turmeric oil, which can be used directly as raw materials in the fields such as the cosmetics, food and pharmacy where different amounts of the oxygenous sesquiterpene and the sesquiterpene are needed.

The invention discloses compound creat injection used for treating hyperpyrexia of a pig and a preparation method thereof, aiming to provide the compound creat injection for treating the hyperpyrexia of the pig with small side effect and the preparation method thereof with the advantages of simple technique and easy realization. Each 100 liters of the injection is prepared by the following raw materials: 50 to 150 kilograms of creat, 0.5 to 5 kilograms of zedoary turmeric oil, 50 to 150 kilograms of Chinese thorowax, 30 to 80 kilograms of garlic, 0.5 kilograms of tween-80, 0.9 kilograms of sodium chloride, 100 kilograms of 95 percent ethanol, the balance being injection water. The compound creat injection is formed by the creat and three traditional Chinese medicines including the Chinese thorowax , the zedoary turmeric oil and the garlic, has the efficacies of antivirus, antibacteria, fever reduction and improvement of the immunity of an organism through reasonable determination of the content of various compositions, strengthens intrinsic phagocytic function, is effective to drug-resistant pathogen of western medicines and the hyperpyrexia of the pig, and relieves the stress reaction of the pig. Simultaneously, the product is traditional Chinese medicine preparation, has small side effect, does not aggravate the burden of the liver and the kidney, and can effectively treat an illness.

The invention discloses a micro emulsion drinking water matrix for livestock, which consists the following constituents in percentage weight: 1.5-11% of oil phase, 4-30% of surfactant, 0-10% of cosurfactant and 50-90% of aqueous phase; the oil phase is the mixture of one or a plurality of tangerine peel oil, blumea oil, rhizoma atractylodis macrocephalae oil, zedoary turmeric oil, peppermint oil, forsythia oil, sweet wormwood oil, clove oil, camphor oil, chili oil, nepeta oil, brucea javanica emulsion, patchouli oil, grape seed oil, evening primrose oil and eucalyptus oil; the surfactant is the mixture of one or a plurality of tween-80, tween-85, polyethyleneglycol hydrogenated castor oil and arlacel-80; the cosurfactant is the mixture of one or a plurality of propylene glycol, glycerol, alcohol, normal butanol and 1,3 butanediol; and the water phase is the distilled water. The invention has the advantages of simple technology, safety and good stability, is widely applied, and has wide prospect.

The invention relates to a turmeric oil and glucose injection which is prepared by the following method: proper injection water is taken and glucose is added to prepare a liquid with certain concentration; then mosatil is added and stirred for dissolving; proper active carbon is added and boiled for a certain time and then filtered; then turmeric oil is additionally taken and proper vitamin E is added, fully stirred and added into Tween-80; proper injection water is taken; the mixed liquor of the turmeric oil and the Tween-80 is slowly added and continuously heated to a certain temperature and stirred until the mixed liquor is milky white. The turmeric oil liquor is mixed with the glucose liquor; the injection water is added until the full dose; the pH is regulated by citric acid liquor and the mixed liquor is stirred for a certain time, filtered, filled and sterilized by a terminal. The medicine composition and the preparation method thereof can obtain the stable turmeric oil and glucose injection, are better than the prior art, ensure the safety of clinical application and can reduce the safety risk.

The invention relates to a compound aromatic turmeric oil gelling agent and its preparing process, wherein each 1000g of the preparation comprises econazole nitrate 12.5g, oil of aromatic turmeric 52.5ml, gel base material 1-30g. The constituents also include sodium hydroxide, propylene glycol, ethanol, polysorbate -80, sorbic acid, sodium metabisulfite, vitamin E and deionized water. The gel base material is the mixture of carbome, sodium carboxymethylcellulose and sodium alginate.

The invention relates to an improved process for preparing aromatic turmeric oil glucose injection which comprises, charging right amount of tween into aromatic turmeric oil, emulsifying sufficiently, preparing glucose solution, charging in right amount of activated charcoal, agitating, boiling a finite period of time, filtering, combining the two liquids, charing water for injection and sodium citrate or citric acid, dissolving with EDTA-2Na, adjusting pH to 3.5-5.0, and producing high capacity injection.

The invention relates to a compound aromatic turmeric oil emulsion type foam aerosol of Econazole nitrate and its preparing process, wherein each 1000mL of the aerosol contains the following constituents (by mass ratio): Econazole nitrate 1-100g, aromatic turmeric oil 1-200g, emulsifying agent 5-250g, preservative agent 0.1-20g, projection agent 50-500g, and balancing dissolvent. The aerosol can be used for treating vaginitis, cervical erosion and uterine neck disease.

The invention discloses traumatic injury ointment containing natural component extract and a preparation method thereof. The traumatic injury ointment is prepared from emu oil, turpentine oil, zedoary turmeric oil, badger oil, aloe oil, borage oil, rose hip oil, wheat source emulsifying agents MONTANOV 82, myrrh extracting solutions, serrate chloranthus root extracting solutions, dipsacus root extracting solutions, notopterygium root extracting solutions, cortex acanthopanacis extracting solutions, carbopol 941, ice crystal forming agents, glycerin and 0.2% ethylparaben alcoholic solutions. Compared with an existing product, the traumatic injury ointment has the advantages of being mild in medicinal property, high in safety, small in side effect and the like, the active substances in natural herbs are adopted for promoting healthy growth of the skin, the normal barrier function of the skin is restored, and most effective components are natural medicinal components, have the remarkable treatment effect on traumatic injury and activate blood to remove blood stasis. In addition, the traumatic injury ointment has the functions of calming, relieving itching, eliminating inflammation, easing the surface layer of the skin and relieving skin scabbing, and has a remarkable treatment effect of relieving traumatic injury conditions.

The invention discloses an application of zedoary turmeric oil in the preparation of psoriasis treatment medicines. Animal tests prove that the zedoary turmeric oil has a substantial curative effect on psoriasis, and can be used for preparing the psoriasis treatment medicines. The zedoary turmeric oil has no toxic side effects, has no obvious untoward effects even after long term administration, and has great clinic application values.

The invention discloses an aromatherapy mosquito-repellent liquid, which is prepared by compounding eucalyptus oil, patchouli oil, zedoary turmeric oil, dementholized peppermint oil, rose oil, star anise oil and isopropanol. The aromatherapy mosquito-repellent liquid has a remarkable mosquito-repellent effect. The mosquito-repellent rate reaches up to 94.2%. Ratio of the components is reasonable. As scent is simple and elegant, the product is easy to accept for people.

The present invention relates to an injection of curcuma oil extract containing aromatic curcumone, curcumone and / or aromatic curcumone derivative. It is made of curcuma oil extract containing active component, surfactant and medium containing water as raw material.

The jelly contains zedoary oil and borneol in the ratio of 1.0933, has pH value of 3-7, and features the functions of treating mycotic vaginitis, senile vaginitis, cervical erosion and other women's diseases.

The invention provides a traditional Chinese medicine pro-liposome injection for treating liver cancer and a preparation process thereof, belonging to the technical field of traditional Chinese medicine preparation. A prescription of the injection comprises 16 to 25 portions of the bunge pricklyash seed olein and 4 to 6 portions of the zedoary turmeric oil by weight. The preparation method comprises the following steps: the bunge pricklyash seed olein medicine materials and the zedoary turmeric oil are prepared to a pro-liposome taking sorbitol as a carrier after being mixed according to a certain ratio and a pro-liposome method. The pro-liposome is shaken by adding water used for injection before being used, and a liposome suspension is formed by hydration to be fed through intravenus drip. A product is a novel pure Chinese drug compound preparation, strengthens the targeting of the drug, enhances the bioavailability, increases the stability of the drug, conceals unpleasant odors, is beneficial to preservation and transportation, has rich raw material sources, low cost and simple preparation technology, and is easy to expand production.

The invention belongs to the technical field of medicines. The invention discloses an application of a pharmaceutical composition using zedoary turmeric oil and borneol as raw materials in preparation of a medicament for treating infertility. Through the pharmaceutical experimental research carried out by scientific researchers, the medicament prepared by using zedoary turmeric oil and borneol as raw materials has a good effect on treating pathological infertility.

The zedoary extractive is prepared with zedoary oil as material and through chromatography with silica gel column, and contains curdione 30-60 wt%, elemenone 15-40 wt%, neo-curdione 1-15 wt%, curcumenol1-20 wt% and no instable benzofuran derivative. The zedoary extractive has high effect, less side effect and high stability, and may be mixed with different medicine carrier to prepare various medicine preparations, such as capsule and injection, for treating viral diseases, cardiac and cerebral vascular diseases and tumor.

The invention discloses a method for extracting turmeric oil. The problems in the prior art that the extraction rate is low, the refined oil quality is low, the production is complicated and production cost is high are solved. The method for extracting turmeric oil disclosed by the invention comprises the following steps: grinding medicinal turmeric, performing enzymolysis, adding water for performing ultrasonic extraction, filtering, standing, performing oil-water layering, and taking the oil phase, so as to obtain the product. According to the method disclosed by the invention, the extraction rate of the oil is high, the obtained oil has excellent quality, the process is simple, and the production cost is low.

The invention provides novel compounds and formulations of turmeric oil, fish oil, aspirin and anti-cancer drugs (paclitaxel) having anti-inflammatory, analgesic and / or anti-cancer activity.

The invention relates to a production method of a zedoary turmeric oil microcapsule. The produced zedoary turmeric oil microcapsule comprises the following main components: 35% to 40% of starch sodium octenylsuccinate, 5% to 30% of zedoary turmeric oil, 10% to 20% of mannitol, 5% to 15% of glucose, 15% to 35% of maltodextrin, 0.5% to 1.5% of sodium tripolyphosphate, 1% to 2% of sodium ascorbate, 0.04% to 0.08% of vitamin E, 0.1% to 0.15% of magnesium ascorbyl palmitate and 0.4% to 0.8% of tricalcium phosphate. The production method has the advantages that all raw materials for preparing the zedoary turmeric oil microcapsule conform to the application range of GB2760, i.e., the raw materials are safe and reliable and can be obtained widely; the microcapsule embedding rate reaches more than 99.5%, so that the microcapsule can be directly taken orally and can also be served as the raw material for preparing capsules, suppositories and gels; and the oxidation stability of the microcapsule product is superior to that of the same-type product in the market, i.e., the microcapsule product can be stored for two years at the temperature of 37+ / -2 DEG C. Therefore, the production technology can be used for producing the microcapsule which is high in medicinal value, simple to store, convenient and safe to use and low in cost.