The invention relates to the technical field of traditional Chinese medicinal material
processing, and discloses a preparation method of radix astragali nanoemulsion, which comprises the following steps: step 1, extracting radix astragali fat-
soluble extract by supercritical extraction; 2, extracting the
astragalus membranaceus subjected to supercritical extraction with water to obtain a water-soluble
astragalus membranaceus extract; step 3, adding
lecithin into the
astragalus membranaceus fat-
soluble extract, and heating to obtain a
system I; 4, diluting the astragalus membranaceus water-
soluble extract, heating, shearing by using a microtube jet high-shear mixer, and homogenizing by using a high-pressure microjet
homogenizer to obtain a
system II; and step 5, centrifuging the
system II, taking supernate, adding water, shearing by using a micro-tube jet high-shear mixer, adding Tween 80, adding the system I while shearing, continuously shearing and uniformly mixing, and performing micro-emulsification by using a high-pressure micro-jet
homogenizer to obtain the
astragalus mongholicus nano-
emulsion. According to the method, the extraction of full-functional components of the astragalus membranaceus can be realized, and the effective components of the astragalus membranaceus are fully utilized in a form of preparing the nano-
emulsion.