27 results about "Soluble extract" patented technology

The invention relates to the technical field of traditional Chinese medicines, in particular to a processing method and a quality control method for toxicity reduction and efficacy enhancement of radix cynanchi bungei. According to the method, the content of alangiine, the content of ellagic acid, the common peak area of characteristic peaks and the content of water-soluble extracts in the wine-roasted berberis scenting decoction pieces are measured by adopting a high performance liquid chromatography (HPLC) method, and subjective assignment is carried out on the characters of the wine-roasted berberis scenting decoction pieces by combining Delphi evaluation to serve as evaluation indexes; the method comprises the following steps: determining the weight coefficient of each index by adopting an analytic hierarchy process-index repeatability correlation mixed weighting method (AHP-CRITIC), and screening the optimal wine roasting process of the Zhuang medicine Tibetan scene by combining the three factors of the frying temperature, the frying time and the yellow wine amount with star point design (CCD)-effect surface (RSM) according to the coefficients. And finally determining the optimal process of stir-frying the radix berberidis with wine as follows: the stir-frying temperature is 150 DEG C, the stir-frying time is 16min, the amount of yellow rice wine is 10%, and moistening is performed for 24h.

The application provides a HPLC-based method for constructing a fingerprint spectrum of Tianyang Qianggu Yin and application thereof, and belongs to the technical field of traditional Chinese medicine detection.The method provided by the application comprises the steps of preparing a test sample solution, preparing a mixed control sample solution, HPLC determination, fingerprint spectrum construction and content determination.The application first establishes a HPLC fingerprint spectrum suitable for water-soluble extracts of Tianyang Qianggu Yin compound, and simultaneously realizes accurate content determination of six components, i.e., neotamanoxin, naringin, alpinumisine A, alpinumisine B, alpinumisine C and icariin.The application has strong specificity, high precision, good repeatability and excellent accuracy.The application provides scientific and controllable technical support for the production quality consistency and efficacy stability of Tianyang Qianggu Yin, and can be used for quality control and batch consistency evaluation of the compound preparation.

WATER-SOLUBLE EXTRACT FROM A PLANT OF THE PRUNUS SPECIES TO PREVENT THE DELETE EFFECTS OF THE EXPOSOME. The present invention relates to the use of a flower extract from a plant of the Rosaceae family and the Prunus genus, or a composition thereof, to protect the skin from the deleterious effects of the exposome, including disruption of the barrier function, neurogenic inflammation, irritation, and oxidative stress. The invention is thus intended to prevent the clinical signs of premature aging, including the appearance of hyperpigmentation spots responsible for loss of skin tone uniformity and skin hyperreactivity.

The extraction method comprises the following steps: adding frozen black sea sheaths into an extraction solvent to form a low-temperature mixture, carrying out ultrasonic extraction, filtering, and collecting filtrate; adding an extraction solvent into filter residues, carrying out ultrasonic extraction, filtering, and collecting filtrate; the extraction step is repeated for multiple times, filtrate collected for multiple times is combined, the solvent is removed, and the black sea sphinga liposoluble extract is obtained. The extraction method has the advantages of low extraction temperature and short operation time, the oil phase and the water phase are directly separated, and the hectochilus formosanus fat-soluble extract provided by the invention has a good effect of preventing and treating the blood fat rise, has a good application prospect and can be used for preparing medicines or functional foods for preventing and treating the blood fat rise.

This invention discloses a method for extracting chlorogenic acids from stevia waste and its applications, including: extracting chlorogenic acids from stevia powder using an alkaline extraction method; and determining whether the chlorogenic acids contain chlorogenic acid, isochlorogenic acid A, and cryptochlorogenic acid. Using stevia waste as raw material, this invention involves solvent extraction, centrifugal filtration, reflux extraction, and chromatographic separation to obtain a fat-soluble extract. This extract is then dissolved and filtered with ethanol, evaporated and concentrated, and freeze-dried to obtain the chlorogenic acid product. This invention extracts and develops chlorogenic acids from stevia waste, solving the problems of environmental pollution and resource waste. The extracted chlorogenic acids contain chlorogenic acid, cryptochlorogenic acid, and isochlorogenic acid A, and have low sugar content. They possess antioxidant, anti-inflammatory, and blood pressure-lowering functions, and can be widely used in food, pharmaceuticals, and health products, demonstrating high application value and realizing the comprehensive utilization of stevia.

The invention provides a method for ultrasonic-assisted extraction of a caulis spatholobi alcohol-soluble extract and total flavonoids, and belongs to the technical field of natural medicine extraction. Ultrasonic extraction is adopted, the mechanical effect and the thermal effect generated by ultrasonic waves can effectively destroy cell walls of caulis spatholobi, permeation of a solvent into cells is accelerated, dissolution of target components is promoted, and therefore the extraction efficiency is improved; according to the method, the yield of the target component can be improved by controlling the material-liquid ratio, the temperature and the time of extraction and the type of the extraction solvent; the method provided by the invention is short in extraction time, low in solvent consumption, low in extraction temperature and high in extraction efficiency.

The invention discloses a method for deeply processing corn, and belongs to the technical field of corn deep processing. According to the method, the corn soaking speed can be increased by adopting a pressurized soaking process, the production efficiency is improved, efficient separation of protein and starch is realized by replacing a traditional sulfurous acid method with a multi-time grinding-screening method, and meanwhile, water generated in the production process is completely recycled, so that the production cost is reduced. The purpose of producing corn deep-processing products without wastewater discharge and chemicals is achieved; the method for deeply processing corn has the characteristics of high product yield, environment-friendly production process, no chemical residue in the product, high production efficiency, low operation cost and good production environment, and in addition, the salt-free condensate water generated after the soluble extracting solution is evaporated and concentrated is reused in the step of washing starch, so that the production cost is greatly reduced. The corn starch with lower ash content can be obtained; therefore, the method for deeply processing the corn has a relatively good application prospect.

The application discloses a tuberose extract and a preparation method and application thereof, and comprises pretreatment, extraction of oil-soluble extract, addition of the pretreated dry flower powder into a solvent, heating extraction, centrifugation, collection of supernatant, filtration, collection of liquid phase, and obtaining of the tuberose extract. The tuberose extract has the functions of antioxidation, inhibition of cortisol and lipid antioxidation, can efficiently remove free radicals at a lower concentration, significantly inhibit lipid peroxidation, help skin resist oxidative damage, effectively regulate cortisol level, and relieve endogenous and exogenous stress. The application has a mild process, extracts fat-soluble active ingredients of tuberose, avoids residue problems of volatile organic solvents, guarantees product safety, and provides a new multifunctional, high-activity and high-safety raw material for the cosmetic industry.

The present application belongs to the technical field of quality control of traditional Chinese medicine, and particularly relates to a quality control method of Ledum palustre L. The quality control method provided by the present application comprises the following processes: S1, identification: thin layer chromatography identification is respectively performed by taking ursolic acid, hyperoside, rutin, aesculetin and aesculin as the control; S2, inspection: the moisture content, total ash content, acid insoluble ash content and alcohol-soluble extract content of the medicinal material are determined; S3, content determination: the total content of volatile oil, three five-ring triterpenes (betulinic acid, oleanolic acid and ursolic acid) and two flavonoid glycosides (hyperoside and preussin) in the medicinal material is determined by using high performance liquid chromatography. The present application combines multi-index component analysis and thin layer chromatography identification, has strong specificity and good reproducibility, can comprehensively and effectively control the quality of Ledum palustre L., and ensures the medicinal effectiveness and safety of Ledum palustre L.

Disclosed is a method for producing biocrude and bioactive substances from microalgae biomass. The method has the steps of mixing and stirring dry microalgae biomass with water and an acid catalyst, heating the mixture at high pressure at a temperature and time based on each individual species or processing the biomass mixture in a colloidal mill with solvent, separating lysed algae cells into non-polar extracts from water-soluble extracts via vacuum filtration, washing the lysed algae cells and non-polar extracts with organic solvents, separating the organic solvent mixture, which has ethanol and long-chain fatty acids, from the remaining biochar via vacuum filtration, and separating the ethanol from the fatty acids via distillation or rotary evaporator to extract bio-oil.

Provided is a method for producing an oily composition having reduced odor and pigment. The method for producing an oily composition according to the present disclosure comprises: a contact step for inducing contact between a plant-derived oil-soluble extract and a porous body; and a solid-liquid separation step for recovering an oily composition by solid-liquid separation of the oil-soluble extract from the porous body.

This invention discloses a glycosylated polypeptide extract from Hericium erinaceus, its preparation method, and its applications, belonging to the technical field of Hericium erinaceus extracts. The technical solution includes: alkaline extraction, where Hericium erinaceus waste powder is subjected to alkaline extraction; the pH of the resulting extract is adjusted to the isoelectric point of Hericium erinaceus protein; the precipitate is repeatedly washed until neutral to obtain Hericium erinaceus protein and polysaccharide precipitates; enzymatic hydrolysis, where the Hericium erinaceus protein and polysaccharide precipitates are added to water, and an enzyme preparation is added for enzymatic hydrolysis to obtain an enzymatic hydrolysate of Hericium erinaceus polypeptides and polysaccharides; polypeptide glycosylation modification, where the enzymatic hydrolysate of Hericium erinaceus polypeptides and polysaccharides undergoes a gradient temperature-changing cyclic CO2-assisted catalytic glycosylation reaction; after the reaction, freeze-drying yields the Hericium erinaceus glycosylated polypeptide extract. This invention enables the resource utilization of Hericium erinaceus waste, while simultaneously preparing a highly active, highly stable glycosylated polypeptide extract that improves the water solubility of lipid-soluble extracts, reducing production costs and expanding its application range.

The invention relates to an optimization method for a pressing process of folium isatidis mouth decoction pieces, which can overcome the defects of leaf medicinal materials in production, transportation and application, and can be used for preparing the folium isatidis mouth decoction pieces by taking a single-factor test as a basis, combining a Box-Behnken design-response surface method and taking indirubin, tryptanthrin, isovitexin and water-soluble extracts as comprehensive evaluation indexes. Four factors including pressing time, pressure, baking temperature and baking time are investigated, an analytic hierarchy process and an entropy weight method are utilized to calculate weight coefficients and comprehensive scores of all indexes to determine the optimal pressing process of the folium isatidis mouth decoction pieces, and the optimal pressing process is close to a predicted value of a result obtained by actual operation, which shows that the process optimization method is good in predictability and high in practicability. The technology is stable and feasible, actual production can be directly guided, the problems of fuzzy technological parameters, large decoction piece quality fluctuation and the like in production are solved, key technical reference can be provided for standardized formulation of the folium isatidis mouth decoction piece pressing technology, and the practical application and popularization value is achieved.

The application discloses an oral care composition and a preparation method thereof, relates to the technical field of oral care compositions, and the oral care composition comprises medium-chain triglycerides, a herbal active compound and fat-soluble vitamins; the herbal active compound comprises frankincense oil extract, drynaria fat-soluble extract and magnolia bark extract. The pure oil phase oral care composition provided by the application can effectively inhibit the breeding of microorganisms, the use of medium-chain triglycerides instead of long-chain fatty acid coconut oil commonly used in traditional oil drawing can greatly reduce the overall viscosity of the oral care composition, and the problem of "greasy and difficult to swallow" of the pure oil phase product is solved, so that the sense of taste is improved. Further, by introducing the herbal active compound and the fat-soluble vitamins, the oral care composition is endowed with the functions of bacteriostasis, caries prevention, anti-allergy repair and mucosal healing, and the above components can be stably dissolved and dispersed in the whole oil system, which is beneficial to improving the product stability and ensuring the stable exertion of the functions.

The invention belongs to the technical field of biological medicines, and particularly relates to a composite medicinal preparation for treating diabetic retinopathy and a preparation method thereof. The traditional Chinese medicine composition comprises traditional Chinese medicine raw materials and auxiliary materials, the traditional Chinese medicine raw materials comprise the following components: an astragalus extract, a salvia miltiorrhiza water-soluble extract, a salvia miltiorrhiza fat-soluble extract, panax notoginseng saponins, a scutellaria baicalensis extract, a ginkgo leaf extract, a lycium barbarum polysaccharide extract and quercetin; the auxiliary materials comprise the following components: soybean lecithin, tween-80, PEG-40 hydrogenated castor oil, medium chain triglyceride oil, glycerol, vitamin E, Arabic gum, maltodextrin, microcrystalline cellulose, PVP K30, croscarmellose sodium and silicon dioxide. On the basis of conventional ophthalmic treatment, multiple components in the formula form a closed-loop cooperative multi-target intervention retina microenvironment, the problems of component dispersion and the like are solved through the combined process, and biocompatibility and compliance are both considered.

The process for the preparation of concentrated water-soluble extracts, comprises the following phases of: e) provision of at least one plant substrate; f) extraction of at least one extract from the plant substrate; c) concentration of the at least one extract comprising the steps of: c1) subjecting the extract to controlled vacuum conditions; c2) applying a temperature below 65 °C to the extract to obtain a concentrated extract; the phase of concentration being earned out until a residual water activity value of the concentrated extract comprised between 0.500 aW and 0.100 aW is achieved.

COSMETIC USE OF AN EXTRACT FROM A PLANT OF THE GENUS ULEX FOR PROTECTING HAIR AGAINST OXIDATIVE DAMAGE INDUCED BY VARIOUS STRESS. The present invention relates to the cosmetic use of a fat-soluble extract from a plant of the genus Ulex for protecting hair against damage induced by exposure to oxidative stress, or for repairing it after such exposure. In particular, the invention relates to the use of such an extract for protecting hair during heat treatment, chemical coloring, perming, exposure to UV radiation, air pollutants, salt, or chlorine.

The application provides a processing optimization method of wet paper wrapped Gastrodia elata, and belongs to the technical field of traditional Chinese medicines.The processing optimization method is as follows: Gastrodia elata is laid on paper wetted by water, and then paper wetted by water is used to cover the Gastrodia elata for baking; single factor experiments are carried out by taking baking time, baking temperature, paper amount and water amount as influence factors, and the content of alcohol-soluble extract, Gastrodia elata element, p-hydroxybenzyl alcohol and barbatusoside components is taken as an evaluation index; baking time, baking temperature and water amount are selected as observation factors, a comprehensive score of the quality of the processed product is taken as a response value, response surface experiments are designed, a quadratic multivariate regression model is established, the parameter value making the comprehensive score reach the best is determined, and the best processing method is obtained: the paper amount is 12 g, the water amount is 30 mL, the baking temperature is 110 DEG C, and the baking time is 200 min.After the Gastrodia elata is baked by the processing optimization method, the obtained product has the properties of mild medicine nature, yin-nourishing and wind-relieving, neutral and slightly warm, and strong spasm-relieving.

The invention discloses a method for producing biological crude oil and bioactive substances from microalgae biomass. The method comprises the following steps: mixing and stirring the dried microalgae biomass with water and an acid catalyst; heating the mixture at high pressure according to the set temperature and time of different species characteristics or treating the biomass mixture in a colloid mill by using a solvent; separating a non-polar extract from a water-soluble extract in the lysed algae cells through vacuum filtration; washing the lysed algae cells and the non-polar extract by using an organic solvent; separating an organic solvent mixture containing ethanol and long-chain fatty acid from the residual biochar through vacuum filtration; ethanol is separated from fatty acids by distillation or rotary evaporation to extract bio-oil.

The invention relates to the technical field of polygonum capitatum processing, in particular to a polygonum capitatum vacuum freeze drying process which comprises the steps of pretreatment, pre-freezing and vacuum drying. According to the method, a pre-freezing method is utilized, the vacuum freeze-drying time is shortened, the process for processing the polygonum capitatum through the vacuum freeze-drying method is researched for the first time, the process parameters are optimized, the content of water-soluble extract and quercetin in the obtained product is obviously higher than that of water-soluble extract and quercetin in a traditional drying process, and pharmacodynamic active ingredients are reserved to the maximum extent.

The invention discloses a Huoxiang Zhengqi multilayer sustained-release dropping pill and a preparation method thereof, and belongs to the field of traditional Chinese medicine preparations, the dropping pill comprises a three-layer structure including an inner core dropping pill, a middle sustained-release layer and an outer quick-release layer, the inner core dropping pill is composed of fat-soluble extract, volatile oil microcapsules and polyethylene glycol 4000, the middle sustained-release layer is composed of hydroxypropyl methylcellulose, sodium alginate and starch, and the outer quick-release layer is composed of hydroxypropyl methylcellulose, sodium alginate and starch. The outer quick-release layer is composed of a water-soluble extract, poloxamer 188 and microcrystalline cellulose, fat-soluble components are extracted through an ultrasonic-assisted enzyme method, volatile oil is separated and purified through a nanofiltration membrane, and the volatile oil micro-capsule is prepared through beta-cyclodextrin clathration, the sequential release of quick release, slow release and controlled release is achieved, the bioavailability is improved by 30-50%, the drug effect lasting time is prolonged by 1.5-2 times, and the preparation method is simple and easy to operate. The stability of the preparation is obviously enhanced, and the production cost is reduced by 40-60%.

This invention provides a method for enhancing the immune response to an antigen in non-human animals. [Solution] A water-soluble extract from a non-woody plant of the genus Hesperaloe contains at least one saponin. Saponins extracted from Hesperaloe biomass may include 25(27)-dehydrofucleastatin, 5(6),25(27)-disdehydroyuccaloyside C, 5(6)-disdehydroyuccaloyside C, flucleastatin, and yuccaloyside. One embodiment of this application involves the administration of saponins containing a Hesperaloe extract. Another embodiment provides the administration of a Hesperaloe-derived immunomodulator containing one or more saponins for the prevention, treatment, and control of one or more conditions in non-human animals. Preferably, a Hesperaloe extract containing one or more saponins may be orally administered to poultry for the prevention and treatment of coccidiosis.

The invention relates to the technical field of traditional Chinese medicine formula granules, in particular to exocarpium benincasae formula granules, a preparation method and an optimization method. The preparation method of the exocarpium benincasae formula granules comprises the steps of decoction and extraction. The decocting and extracting step comprises the following steps: putting the Chinese waxgourd peel decoction pieces into an extracting tank, and soaking the Chinese waxgourd peel decoction pieces in water for 1-2 hours at the feeding temperature and the soaking temperature of 50-65 DEG C; sequentially carrying out three times of extraction, combining the extracting solutions obtained by each time of extraction, and filtering to obtain a Chinese waxgourd peel filtrate; wherein during each extraction, the amount of water added into the extraction tank is 8-12 times of the weight of the Chinese waxgourd peel decoction pieces, and the time of each extraction is 0.5-1 h. According to the preparation method, the paste yield, the alcohol-soluble extract content and the guanosine content of the Chinese waxgourd peel formula granules are improved.

The invention discloses a suberect spatholobus stem decoction piece quality evaluation method based on a'excellent shape and high quality 'theory, and belongs to the technical field of traditional Chinese medicine quality evaluation. According to the method, key character indexes (the number of turns, the diameter and the delta E) are screened out by utilizing principal component analysis, correlation analysis and partial least squares discriminant analysis (OPLS-DA) by measuring the external character indexes (powder color delta E * > = 35, the diameter and the maximum number of turns of a tangent plane) and the internal quality indexes (catechin, epicatechin and the content of alcohol-soluble extracts) of the caulis spatholobi decoction pieces; and a quantitative correlation and prediction model of the content of the components and the content of the internal components is established. By setting a key character threshold (delta E * > = 35, the number of turns > = 5, and the diameter > = 5.0 cm) or using a prediction model, rapid and objective evaluation of the quality of the caulis spatholobi decoction pieces can be realized, traditional subjective identification and complex instrument detection are effectively replaced, and a reliable standard is provided for quality control and market circulation of medicinal materials.

The application belongs to the technical field of biological medicine, and particularly relates to a compound drug preparation for treating diabetic retinopathy and a preparation method thereof. The compound drug preparation is composed of traditional Chinese medicine raw materials and auxiliary materials. The traditional Chinese medicine raw materials comprise the following components: Astragalus extract, Danshen water-soluble extract, Danshen fat-soluble extract, Panax notoginseng total saponins, Huangqi extract, Ginkgo biloba leaf extract, Medlar polysaccharide extract and quercetin. The auxiliary materials comprise the following components: Soybean lecithin, Tween-80, PEG-40 hydrogenated castor oil, medium-chain triglyceride oil, glycerol, vitamin E, acacia gum, malt dextrin, microcrystalline cellulose, PVP K30, cross-linked sodium carboxymethyl cellulose and silicon dioxide. On the basis of conventional ophthalmic treatment, the application forms a closed-loop synergistic multi-target intervention retinal microenvironment through multiple components, solves the problems of component dispersion through a combination process, and takes into account biocompatibility and compliance.

This invention discloses a Lushan white velvet tea product, its preparation method, and its application. The invention uses the leaves of Lushan white velvet tea (Litsea coreana var. bairongcha) as raw material, processing them through withering, fixation, fermentation, and drying to produce a Lushan white velvet tea product. This tea product has high levels of water-soluble extracts, tea polyphenols, and soluble sugars, and is caffeine-free. Regarding volatile components, it is rich in terpenes, aldehydes, hydrocarbons, and alcohols, which interact to create the unique flavor properties of Lushan white velvet tea. Therefore, the Lushan white velvet tea of ​​this invention can be applied to the preparation of caffeine-free natural tea beverages, laying a solid foundation for the development and utilization of traditional caffeine-free beverage plant resources.

The invention discloses a processing method based on codonopsis pilosula pharmacodynamic substances and activity thereof, and relates to the field of traditional Chinese medicine processing, and the processing method comprises the following steps: S1, taking a codonopsis pilosula medicinal material, and pretreating to obtain codonopsis pilosula decoction pieces; s2, the codonopsis pilosula decoction pieces are processed, the processing is rice frying, and the processing parameters are as follows: rice is selected as an auxiliary material according to the mass ratio of codonopsis pilosula to the auxiliary material being 100: 20, the rice is put into a frying pan, the rice is heated to smoke with medium fire, the codonopsis pilosula decoction pieces are put into the frying pan, and stir-frying is performed for 8-12 min under the conditions of 150-170 DEG C and 2.2-2.6 kW; according to the processing method, the content of lobetyolin, the alcohol-soluble extract, the appearance property and the moisture in the codonopsis pilosula are used as detection indexes, key parameters of the codonopsis pilosula processing technology are accurately quantified and optimized, quality fluctuation caused by manual operation differences is effectively eliminated, and the quality of the codonopsis pilosula is improved. And the advantages in the aspects of pharmacodynamic substances and biological activity of the codonopsis pilosula are reserved and stimulated to the maximum extent.