52 results about "Soluble extract" patented technology

The invention relates to a multilayer hollow body with high leaching resistance, comprising: I. an inner layer I consisting of a molding composition based on PA612, PA610, PA1010, PA1012 and / or PA1212; iI. Optionally a tackifier layer II consisting of a molding composition based on the following components: a) 0 to 80 parts by weight of a polyamide selected from the group consisting of PA6, PA66, PA6 / 66, b) 0 to 100 parts by weight of a polyamine-polyamide copolymer, c) 0 to 80 parts by weight of a polyamide selected from the group consisting of PA11, PA12, PA612, PA1010, PA1012, PA1212, III. A layer III consisting of an ethylene-vinyl alcohol copolymer molding composition, wherein no more than 0.2 g / m < 2 > of insoluble extract and no more than 7.0 g / m < 2 > of soluble extract are washed out of the multilayer hollow body as the entire system upon first exposure to fuel.

The invention discloses a method for integrally extracting active ingredients from seedless roxburgh rose (rosa sterilis) pomace and application. According to the method, the contents of multiple water-soluble and fat-soluble components of the seedless roxburgh rose fruit, juice and pomace are measured, the proportion of each component in the fruit is analyzed, and the availability of the seedless roxburgh rose pomace resource is discussed. Further experiments find that fat-soluble components in the seedless roxburgh rose residues can be extracted by a supercritical CO2 extraction technology, and water-soluble components in the seedless roxburgh rose residues can be extracted by a low-temperature high-pressure crushing extraction technology. The formed fat-soluble extract and water-soluble extract are proved to have a variety of biological activities and uses. The two extraction technologies are combined for extraction, and comprehensive utilization of the two components in the seedless roxburgh rose residues can be achieved. According to the method, processing and utilization of the seedless roxburgh rose can be achieved, and reference is provided for quality evaluation and comprehensive development and utilization of the seedless roxburgh rose.

The invention relates to the technical field of traditional Chinese medicines, in particular to a processing method and a quality control method for toxicity reduction and efficacy enhancement of radix cynanchi bungei. According to the method, the content of alangiine, the content of ellagic acid, the common peak area of characteristic peaks and the content of water-soluble extracts in the wine-roasted berberis scenting decoction pieces are measured by adopting a high performance liquid chromatography (HPLC) method, and subjective assignment is carried out on the characters of the wine-roasted berberis scenting decoction pieces by combining Delphi evaluation to serve as evaluation indexes; the method comprises the following steps: determining the weight coefficient of each index by adopting an analytic hierarchy process-index repeatability correlation mixed weighting method (AHP-CRITIC), and screening the optimal wine roasting process of the Zhuang medicine Tibetan scene by combining the three factors of the frying temperature, the frying time and the yellow wine amount with star point design (CCD)-effect surface (RSM) according to the coefficients. And finally determining the optimal process of stir-frying the radix berberidis with wine as follows: the stir-frying temperature is 150 DEG C, the stir-frying time is 16min, the amount of yellow rice wine is 10%, and moistening is performed for 24h.

The present invention relates to the technical field of skin care products, specifically disclosing an oil-soluble extract composition with anti-allergic and soothing effects and its use. The oil-soluble extract composition with anti-allergic and soothing effects comprises the following components: an extract of the flower, leaf, and vine of Cyperus rotundus, an extract of Dendrobium nobile, an extract of Sapindus mukorossi, an extract of Rosmarinus officinalis, an extract of Calendula officinalis, and a solvent. This composition has the advantage of accelerating skin repair.

The present invention relates to a method for optimizing the full utilization of cacao pod husks comprising the steps of debacterizing the pod surface and opening cacao the pods, separating the cacao pod husks from, cacao pulp, cacao placenta, cacao beans and cacao bean hulls, and drying separated cacao pod husks wherein separated and dried cacao pod husks are further processed by a method comprising the steps of a) grinding the cacao pod husks; b) optional acid extraction; c) a first enzymatic treatment; d) alkaline solubilization; e) a first decantation with centrifuge; f) ultrafiltration; g) acid extraction; h) a second decantation with centrifuge; i) a second enzymatic treatment; j) ultrafiltration and extract purification; k) concentration of the extract; l) drying of the concentrated extract. The invention also relates to extracts and compositions obtained thereof and their applications.

The application provides a HPLC-based method for constructing a fingerprint spectrum of Tianyang Qianggu Yin and application thereof, and belongs to the technical field of traditional Chinese medicine detection.The method provided by the application comprises the steps of preparing a test sample solution, preparing a mixed control sample solution, HPLC determination, fingerprint spectrum construction and content determination.The application first establishes a HPLC fingerprint spectrum suitable for water-soluble extracts of Tianyang Qianggu Yin compound, and simultaneously realizes accurate content determination of six components, i.e., neotamanoxin, naringin, alpinumisine A, alpinumisine B, alpinumisine C and icariin.The application has strong specificity, high precision, good repeatability and excellent accuracy.The application provides scientific and controllable technical support for the production quality consistency and efficacy stability of Tianyang Qianggu Yin, and can be used for quality control and batch consistency evaluation of the compound preparation.

WATER-SOLUBLE EXTRACT FROM A PLANT OF THE PRUNUS SPECIES TO PREVENT THE DELETE EFFECTS OF THE EXPOSOME. The present invention relates to the use of a flower extract from a plant of the Rosaceae family and the Prunus genus, or a composition thereof, to protect the skin from the deleterious effects of the exposome, including disruption of the barrier function, neurogenic inflammation, irritation, and oxidative stress. The invention is thus intended to prevent the clinical signs of premature aging, including the appearance of hyperpigmentation spots responsible for loss of skin tone uniformity and skin hyperreactivity.

The extraction method comprises the following steps: adding frozen black sea sheaths into an extraction solvent to form a low-temperature mixture, carrying out ultrasonic extraction, filtering, and collecting filtrate; adding an extraction solvent into filter residues, carrying out ultrasonic extraction, filtering, and collecting filtrate; the extraction step is repeated for multiple times, filtrate collected for multiple times is combined, the solvent is removed, and the black sea sphinga liposoluble extract is obtained. The extraction method has the advantages of low extraction temperature and short operation time, the oil phase and the water phase are directly separated, and the hectochilus formosanus fat-soluble extract provided by the invention has a good effect of preventing and treating the blood fat rise, has a good application prospect and can be used for preparing medicines or functional foods for preventing and treating the blood fat rise.

This invention discloses a method for extracting chlorogenic acids from stevia waste and its applications, including: extracting chlorogenic acids from stevia powder using an alkaline extraction method; and determining whether the chlorogenic acids contain chlorogenic acid, isochlorogenic acid A, and cryptochlorogenic acid. Using stevia waste as raw material, this invention involves solvent extraction, centrifugal filtration, reflux extraction, and chromatographic separation to obtain a fat-soluble extract. This extract is then dissolved and filtered with ethanol, evaporated and concentrated, and freeze-dried to obtain the chlorogenic acid product. This invention extracts and develops chlorogenic acids from stevia waste, solving the problems of environmental pollution and resource waste. The extracted chlorogenic acids contain chlorogenic acid, cryptochlorogenic acid, and isochlorogenic acid A, and have low sugar content. They possess antioxidant, anti-inflammatory, and blood pressure-lowering functions, and can be widely used in food, pharmaceuticals, and health products, demonstrating high application value and realizing the comprehensive utilization of stevia.

The invention discloses a phoebe zhennan water-soluble extract as well as an extraction method and application thereof, and belongs to the technical field of medicine extraction. The method comprises the following steps: S1, crushing a phoebe zhennan raw material, adding 6 times of water, extracting twice, 1 hour each time, and combining filtrates; s2, concentrating the filtrate obtained in the step S1 under reduced pressure until the volume is 1: 1, standing at low temperature, and taking supernate; and S3, centrifuging the supernate obtained in S2, discarding the precipitate, concentrating under reduced pressure, and drying at low temperature to obtain the phoebe zhennan water-soluble extract. The invention discloses a phoebe zhennan water-soluble extract and an extraction method and application thereof. The phoebe zhennan water-soluble extract has efficient broad-spectrum antiviral activity and can effectively inhibit respiratory virus activity.

The invention provides a method for ultrasonic-assisted extraction of a caulis spatholobi alcohol-soluble extract and total flavonoids, and belongs to the technical field of natural medicine extraction. Ultrasonic extraction is adopted, the mechanical effect and the thermal effect generated by ultrasonic waves can effectively destroy cell walls of caulis spatholobi, permeation of a solvent into cells is accelerated, dissolution of target components is promoted, and therefore the extraction efficiency is improved; according to the method, the yield of the target component can be improved by controlling the material-liquid ratio, the temperature and the time of extraction and the type of the extraction solvent; the method provided by the invention is short in extraction time, low in solvent consumption, low in extraction temperature and high in extraction efficiency.

The biologically active substance is obtained or capable of being obtained by alkaline extraction, using an aqueous solution of at least one base in the presence of at least one reducing agent, of at least one macroscopic edible mushroom reduced to powder, to obtain a mixture having a liquid portion containing the soluble extracted materials and a solid portion formed of insoluble solid particles; filtering the resulting mixture to remove the solid portion and optionally clarifying the liquid portion; neutralising the liquid portion using a cation exchange resin and optionally filtering / clarifying the liquid portion thus neutralised to obtain the biologically active substance in the aqueous phase; and treating the resulting aqueous phase, the treatment being selected from dilution in water, concentration, dehydration and lyophilisation to obtain a biologically active substance which is, respectively, more diluted in water, in an aqueous solution more concentrated, dehydrated in powder form or lyophilised.

The invention discloses a method for deeply processing corn, and belongs to the technical field of corn deep processing. According to the method, the corn soaking speed can be increased by adopting a pressurized soaking process, the production efficiency is improved, efficient separation of protein and starch is realized by replacing a traditional sulfurous acid method with a multi-time grinding-screening method, and meanwhile, water generated in the production process is completely recycled, so that the production cost is reduced. The purpose of producing corn deep-processing products without wastewater discharge and chemicals is achieved; the method for deeply processing corn has the characteristics of high product yield, environment-friendly production process, no chemical residue in the product, high production efficiency, low operation cost and good production environment, and in addition, the salt-free condensate water generated after the soluble extracting solution is evaporated and concentrated is reused in the step of washing starch, so that the production cost is greatly reduced. The corn starch with lower ash content can be obtained; therefore, the method for deeply processing the corn has a relatively good application prospect.

The invention discloses a preparation method and application of a dendrobe salt roasted product, and belongs to the technical field of traditional Chinese medicines. The preparation method comprises the following steps: drying fresh dendrobium huoshanense strips serving as a raw material, adding saline water for moistening until the core of the dendrobium huoshanense is completely penetrated, and frying to obtain the salt roasted dendrobium huoshanense product. According to the preparation method, a single factor is combined with a Box-Behnken response surface method, the contents of main medicinal components including total polysaccharides, total flavonoids, alcohol-soluble extracts and water-soluble extracts of dendrobium huoshanense are taken as evaluation indexes, comprehensive scoring is carried out by combining an entropy weight method, and the preparation method of the dendrobium huoshanense salt roasted product is obtained through optimization. The quality of the dendrobium huoshanense salt honey-fried product obtained by the method is obviously improved, the total polysaccharide content and the alcohol-soluble extract content of the dendrobium huoshanense salt honey-fried product exceed 12.82% and 51.25% in the specification of pharmacopeia respectively, and the effect of improving hyperthyroidism yin deficiency is also obviously improved.

The application discloses a tuberose extract and a preparation method and application thereof, and comprises pretreatment, extraction of oil-soluble extract, addition of the pretreated dry flower powder into a solvent, heating extraction, centrifugation, collection of supernatant, filtration, collection of liquid phase, and obtaining of the tuberose extract. The tuberose extract has the functions of antioxidation, inhibition of cortisol and lipid antioxidation, can efficiently remove free radicals at a lower concentration, significantly inhibit lipid peroxidation, help skin resist oxidative damage, effectively regulate cortisol level, and relieve endogenous and exogenous stress. The application has a mild process, extracts fat-soluble active ingredients of tuberose, avoids residue problems of volatile organic solvents, guarantees product safety, and provides a new multifunctional, high-activity and high-safety raw material for the cosmetic industry.

To provide a food / beverage preserving / quality-improving agent and food / beverage preserving / quality-improving method, containing, as active ingredients, a food material that does not affect flavor of food even at a concentration that exhibits a shelf life improving effect and that exhibits further stable antibacterial activity.SOLUTION: A food / beverage preserving / quality-improving agent contains, as active ingredients, one or more types selected from groups consisting of water-soluble extracts of: horseradish and brewed vinegar; acetic acid, lactic acid, citric acid, malic acid, fumaric acid, adipic acid, gluconic acid, succinic acid and salts thereof; glycine, alanine, milt protein, poly-lysine, nisin, degraded pectin, hop extract, capsaicin extract, licorice oil extract, egg-white lysozyme, calcined calcium, sucrose fatty acid ester, glycerin fatty acid ester, and thiamine dilaurylsulfate.SELECTED DRAWING: None

The present application belongs to the technical field of quality control of traditional Chinese medicine, and particularly relates to a quality control method of Ledum palustre L. The quality control method provided by the present application comprises the following processes: S1, identification: thin layer chromatography identification is respectively performed by taking ursolic acid, hyperoside, rutin, aesculetin and aesculin as the control; S2, inspection: the moisture content, total ash content, acid insoluble ash content and alcohol-soluble extract content of the medicinal material are determined; S3, content determination: the total content of volatile oil, three five-ring triterpenes (betulinic acid, oleanolic acid and ursolic acid) and two flavonoid glycosides (hyperoside and preussin) in the medicinal material is determined by using high performance liquid chromatography. The present application combines multi-index component analysis and thin layer chromatography identification, has strong specificity and good reproducibility, can comprehensively and effectively control the quality of Ledum palustre L., and ensures the medicinal effectiveness and safety of Ledum palustre L.

Disclosed is a method for producing biocrude and bioactive substances from microalgae biomass. The method has the steps of mixing and stirring dry microalgae biomass with water and an acid catalyst, heating the mixture at high pressure at a temperature and time based on each individual species or processing the biomass mixture in a colloidal mill with solvent, separating lysed algae cells into non-polar extracts from water-soluble extracts via vacuum filtration, washing the lysed algae cells and non-polar extracts with organic solvents, separating the organic solvent mixture, which has ethanol and long-chain fatty acids, from the remaining biochar via vacuum filtration, and separating the ethanol from the fatty acids via distillation or rotary evaporator to extract bio-oil.

The invention relates to the technical field of textiles, in particular to a composite textile fabric with antibacterial and deodorant functions and a preparation method of the composite textile fabric. The preparation method of the fabric comprises the following steps: uniformly mixing the cotton fibers, the lyocell fibers, the China hemp fibers and the bamboo fibers, and processing into blended yarns; weaving the blended yarns into gray cloth, and then sequentially performing cloth boiling, mercerizing, dyeing, sizing and preshrinking to obtain premixed cloth; adding the premixed cloth into the antibacterial solution, stirring, then drying, and finally singeing and corroding wool to obtain the composite textile fabric with the antibacterial and deodorant functions, the antibacterial solution is a mixed solution of a rosemary alcohol-soluble extract and chitosan. Through the synergistic effect of natural antibacterial components of the bamboo fibers and the rosemary alcohol-soluble extract-chitosan antibacterial solution, after the fabric is soaped for 50 times, the antibacterial rate of the fabric to escherichia coli, staphylococcus aureus and other bacteria is still kept at 95% or above, and the antibacterial performance of the fabric is remarkably improved compared with that of a traditional single-coating fabric.

Provided is a method for producing an oily composition having reduced odor and pigment. The method for producing an oily composition according to the present disclosure comprises: a contact step for inducing contact between a plant-derived oil-soluble extract and a porous body; and a solid-liquid separation step for recovering an oily composition by solid-liquid separation of the oil-soluble extract from the porous body.

The utility model discloses a system of making palatable tea beverage, include: extraction device, and it is in containing water and tea leaf, be used for to tea water mixture carries out heating and forms high concentration's tea liquid to extract the water-soluble extract in tea leaf, storage device is linked together with extraction device, is used for to the high concentration's tea liquid of coming from extraction device storage, mixing device, and it is linked together with storage device through pipeline, is used for the high concentration's tea liquid and water in storage device are mixed and get palatable tea beverage, the utility model discloses can prepare the tea drink of different concentration according to individual taste, and the concentration of the tea soup obtained can be stable and unchangeable, avoid the fluctuation of too thick and too light in the process of drinking tea.

This invention discloses a processing method for promoting the dissolution of effective substances in buffalo horn, belonging to the field of drug extraction technology, including the following steps: S1, crushing raw buffalo horn into particles of 3-5 mm to obtain buffalo horn granules; S2, adding the buffalo horn granules to distilled water for hydrolysis for 30-60 minutes to obtain buffalo horn hydrolysate; the hydrolysis temperature is 130-230℃ and the pressure is 2-20 MPa; S3, filtering the hydrolysate and directly collecting the filtrate, or evaporating the filtrate to dryness to obtain the processed buffalo horn product. This invention uses microwave hydrolysis, which can hydrolyze the insoluble substances in buffalo horn in a short time. The average buffalo horn extract content of the processed buffalo horn product reaches 18.57%, which is nearly six times higher than the extract content of long-term decoction, greatly increasing the extract content of buffalo horn. Therefore, microwave hydrolysis of buffalo horn dissolves the sample more completely than decoction, and can significantly increase the water-soluble extract content of buffalo horn.

This invention discloses a glycosylated polypeptide extract from Hericium erinaceus, its preparation method, and its applications, belonging to the technical field of Hericium erinaceus extracts. The technical solution includes: alkaline extraction, where Hericium erinaceus waste powder is subjected to alkaline extraction; the pH of the resulting extract is adjusted to the isoelectric point of Hericium erinaceus protein; the precipitate is repeatedly washed until neutral to obtain Hericium erinaceus protein and polysaccharide precipitates; enzymatic hydrolysis, where the Hericium erinaceus protein and polysaccharide precipitates are added to water, and an enzyme preparation is added for enzymatic hydrolysis to obtain an enzymatic hydrolysate of Hericium erinaceus polypeptides and polysaccharides; polypeptide glycosylation modification, where the enzymatic hydrolysate of Hericium erinaceus polypeptides and polysaccharides undergoes a gradient temperature-changing cyclic CO2-assisted catalytic glycosylation reaction; after the reaction, freeze-drying yields the Hericium erinaceus glycosylated polypeptide extract. This invention enables the resource utilization of Hericium erinaceus waste, while simultaneously preparing a highly active, highly stable glycosylated polypeptide extract that improves the water solubility of lipid-soluble extracts, reducing production costs and expanding its application range.

The invention relates to an optimization method for a pressing process of folium isatidis mouth decoction pieces, which can overcome the defects of leaf medicinal materials in production, transportation and application, and can be used for preparing the folium isatidis mouth decoction pieces by taking a single-factor test as a basis, combining a Box-Behnken design-response surface method and taking indirubin, tryptanthrin, isovitexin and water-soluble extracts as comprehensive evaluation indexes. Four factors including pressing time, pressure, baking temperature and baking time are investigated, an analytic hierarchy process and an entropy weight method are utilized to calculate weight coefficients and comprehensive scores of all indexes to determine the optimal pressing process of the folium isatidis mouth decoction pieces, and the optimal pressing process is close to a predicted value of a result obtained by actual operation, which shows that the process optimization method is good in predictability and high in practicability. The technology is stable and feasible, actual production can be directly guided, the problems of fuzzy technological parameters, large decoction piece quality fluctuation and the like in production are solved, key technical reference can be provided for standardized formulation of the folium isatidis mouth decoction piece pressing technology, and the practical application and popularization value is achieved.

The invention relates to swimming bladders, in particular to a processing method of red-mouth swimming bladders, which is realized according to the following steps: cutting dry red-mouth swimming bladders into small square blocks with the length of 1-2cm, and taking quantitative cut clean swimming bladder rubber blocks for later use; taking an auxiliary material talcum powder or clam powder, putting the auxiliary material talcum powder or clam powder into a stir-frying container, heating to a specified temperature, adding the clean swimming bladder blocks, uniformly stir-frying for a specified time, quickly taking out the swimming bladder blocks, screening out the auxiliary material, and cooling; the dosage of the auxiliary materials is appropriate when the swim bladder can be completely buried and the rest part is left during frying. Wherein the auxiliary materials are fried at the temperature of 160-170 DEG C for 1.5 minutes. After stir-frying with clam meal or talcum powder, the finished product has no significant difference in character, puffing degree and water-soluble extract, and the male swim bladder and the female swim bladder have significant difference due to the difference in meat thickness. The technological parameters are stable and feasible, repeatability is achieved, and the processing technology end point error caused by subjective judgment is avoided.

The present invention relates to a composition for use in the treatment of cancer, the composition comprising an aqueously-soluble extract of curcumin and an aqueously-soluble extract of Sutherlandia frutescens. The present invention further relates to the method and use of such a composition in the treatment of cancer.

The application discloses an oral care composition and a preparation method thereof, relates to the technical field of oral care compositions, and the oral care composition comprises medium-chain triglycerides, a herbal active compound and fat-soluble vitamins; the herbal active compound comprises frankincense oil extract, drynaria fat-soluble extract and magnolia bark extract. The pure oil phase oral care composition provided by the application can effectively inhibit the breeding of microorganisms, the use of medium-chain triglycerides instead of long-chain fatty acid coconut oil commonly used in traditional oil drawing can greatly reduce the overall viscosity of the oral care composition, and the problem of "greasy and difficult to swallow" of the pure oil phase product is solved, so that the sense of taste is improved. Further, by introducing the herbal active compound and the fat-soluble vitamins, the oral care composition is endowed with the functions of bacteriostasis, caries prevention, anti-allergy repair and mucosal healing, and the above components can be stably dissolved and dispersed in the whole oil system, which is beneficial to improving the product stability and ensuring the stable exertion of the functions.

The invention relates to a good-vision-brightening series traditional Chinese medicine composition for liver and kidney deficiency and fire excess from yin deficiency type cataract and a preparation method of the good-vision-brightening series traditional Chinese medicine composition. The traditional Chinese medicine composition comprises cornu bubali concentrated powder. The preparation method of the cornu bubali concentrated powder comprises the following steps: (1) treating cornu bubali tip parts; (2) treating a corner pile part; and (3) preparing the buffalo horn concentrated powder. According to the buffalo horn extraction method, an extraction mode of combining enzymolysis of two enzymes with ultrasound is adopted, and the enzymolysis time and the ultrasound time are controlled at the same time, so that the buffalo horn extraction effect is improved to the maximum extent, and the horn pile extraction rate, the total nitrogen content of concentrated powder, the tryptophan content of the concentrated powder and the water-soluble extract content of the concentrated powder in the buffalo horn are greatly improved.

The invention discloses a chicory fat-soluble extract as well as a preparation method and application thereof. The active monomer components of the extract comprise lactucin, lactucin, 8-deoxylactucin and esculetin, and the extract has the effect of inhibiting proliferation of tumor cells SH-SY5Y, KGN and pc3, also has certain effects of removing DPPH free radicals and inhibiting ABTS, has the effect of inhibiting macrophage RAW264.7 from releasing inflammatory factors NO and IL-6, has the effect of inhibiting tumor cell proliferation, has the effect of inhibiting tumor cell proliferation, has the effect of inhibiting tumor cell proliferation, has the effect of inhibiting tumor cell proliferation, has the effect of inhibiting tumor cell proliferation, has the effect of inhibiting tumor cell proliferation, has the effect of inhibiting tumor cell proliferation, and has the effect of inhibiting tumor cell proliferation. The invention provides the application of medicines or health-care products for resisting oxidation, delaying senescence, resisting inflammation, preventing and treating cancers and the like, and also can be applied to natural antioxidants. The invention also provides medicines for treating obesity and diseases caused by obesity, such as hyperlipidemia, hypertension, diabetes, fatty liver, coronary heart disease, sleep apnea syndrome and the like, and medicines and health care products related to the diseases.

The invention belongs to the technical field of biological medicines, and particularly relates to a composite medicinal preparation for treating diabetic retinopathy and a preparation method thereof. The traditional Chinese medicine composition comprises traditional Chinese medicine raw materials and auxiliary materials, the traditional Chinese medicine raw materials comprise the following components: an astragalus extract, a salvia miltiorrhiza water-soluble extract, a salvia miltiorrhiza fat-soluble extract, panax notoginseng saponins, a scutellaria baicalensis extract, a ginkgo leaf extract, a lycium barbarum polysaccharide extract and quercetin; the auxiliary materials comprise the following components: soybean lecithin, tween-80, PEG-40 hydrogenated castor oil, medium chain triglyceride oil, glycerol, vitamin E, Arabic gum, maltodextrin, microcrystalline cellulose, PVP K30, croscarmellose sodium and silicon dioxide. On the basis of conventional ophthalmic treatment, multiple components in the formula form a closed-loop cooperative multi-target intervention retina microenvironment, the problems of component dispersion and the like are solved through the combined process, and biocompatibility and compliance are both considered.