96results about How to "Improve the purification effect" patented technology

The invention discloses a purification method of a GLP-1 analogue crude peptide. The purification method comprises the following steps: treating a sample, preparing a mobile phase, carrying out purification balance, loading the sample, carrying out post-balance and eluting. The purification method aims at single impurities which are difficult to remove near a main peak, solves the problems of high purification difficulty, low recovery rate and high cost in the prior art, also has an obvious removal effect on front and rear impurities which are difficult to remove in crude stemeglutide or crude tilpoitide, reduces the purification difficulty, and has a great application prospect.

The invention discloses a high-activity TET dioxygenase mutant as well as a construction method and application thereof. The TET dioxygenase mutant is obtained from an amino acid sequence of wild type TET dioxygenase as shown in SEQ ID NO.1 according to any one of the following mutation modes: a, the 150th proline is mutated into alanine; and b, proline at the 150th site is mutated into alanine, and isoleucine at the 235th site is mutated into methionine. The TET dioxygenase mutant provided by the invention can be stabilized in an escherichia coli system, the purification effect is good, the preparation difficulty is reduced, and the activity is remarkably improved compared with that of a wild type. The methylation gene transformation effect is far better than that of a traditional bisulfite transformation method, and the method has a good application prospect.

The invention discloses a pressure swing adsorption device of a hydrogen production system. The pressure swing adsorption device comprises a first adsorption tower, a second adsorption tower, a waste gas emission unit, a hydrogen input pipe, a hydrogen output pipe, a program control valve group and a PLC (Programmable Logic Controller) control system, according to the device, a plurality of adsorption layers are respectively arranged in the first adsorption tower and the second adsorption tower, and the pressure change of each adsorption tower in different adsorption and regeneration stages is controlled, so that the intelligent control of the pressure swing adsorption hydrogen production process is realized, and the first adsorption tower and the second adsorption tower alternately perform adsorption and regeneration; compared with the traditional two independent steps of deoxidation and drying, the method has the advantages that the influence on the purification effect of hydrogen due to flow connection is avoided, the hydrogen purification flow is efficiently integrated, and the purification effect and efficiency of hydrogen are improved; by controlling the opening and closing time and sequence of the program control valve group, when one adsorption tower performs adsorption operation, the other adsorption tower performs regeneration operation, so that the overall efficiency and yield of the system are improved.

The food safety detection equipment disclosed by the invention comprises a sampling mechanism, a multi-station turntable device, a centrifugal device, a conveying mechanism, a detection device, a reagent adding device and an extraction mechanism. The sampling mechanism is provided with a sampling table; the multi-station turntable device is provided with a first containing part; the centrifugal device comprises a rotating frame and a first driving mechanism, and the rotating frame is provided with a second containing part; the first conveying mechanism is used for transferring the sample containers among the sampling mechanism, the multi-station turntable device and the centrifugal device; the detection device is provided with a third containing part, a fourth containing part, a first image acquisition device and a second image acquisition device; the reagent adding device is used for adding reagents to form a first sample and a second sample; the extraction mechanism comprises a manipulator and a pipette and is used for extracting the first sample and the second sample. The device has the advantages of high automation degree, good soaking and purifying effects, high detection precision and integration of multiple detection means.

The invention belongs to the field of composite materials, and particularly relates to super-hydrophobic MOF-based polyurethane sponge added with a green inorganic flame retardant and used for oil-water separation and a preparation method of the super-hydrophobic MOF-based polyurethane sponge. The preparation method comprises the following steps: firstly, preparing Ni-MOF by adopting a solvothermal method, then respectively grafting the Ni-MOF and Mg (OH) 2 / Al (OH) 3 to octadecyltrimethoxysilane / dodecyltrimethoxysilane, and then loading Ni-MOF-ODTMS / DTMS and Mg (OH) 2 / Al (OH) 3-ODTMS / DTMS onto a polyurethane sponge by using polydimethylsiloxane as an adhesive, so as to obtain the MOF-based polyurethane sponge. The polyurethane sponge shows excellent super-hydrophobicity / super-lipophilicity and oil-water separation capacity, and the oil-water separation efficiency still reaches 99.2% after 10 times of circulation oil absorption. Meanwhile, the MOF-based polyurethane sponge shows excellent flame retardant property, so that the possibility of secondary fire caused by petroleum leakage accidents is avoided.

The invention provides a high-purity quartz preparation method and product through complexing impurity removal and preferential corrosion co-processing, and the method comprises the following steps: carrying out sand making on quartz raw ore to obtain first quartz particles; performing pre-purification treatment on the first quartz particles to obtain second quartz particles; performing complexing impurity removal on the second quartz particles to obtain third quartz particles; carrying out flotation on the third quartz particles, and cleaning to obtain fourth quartz particles; and carrying out selective corrosion and tailing discarding on the fourth quartz particles, and filtering, washing and drying to obtain the high-purity quartz. According to the preparation method of the high-purity quartz, the requirement on the high-purity quartz raw material is relatively low, and the preparation of a product with higher purity under the same-quality raw material can be realized.

The invention discloses a preparation method of high-purity fused quartz powder, and the preparation method specifically comprises the following steps: S1, crushing; s2, fully washing the quartz powder with water, and then removing impurities; s3, feeding the crushed particles subjected to impurity removal into a pickling tank for pickling; s4, dissolving the crude product in two times of alkaline solution, carrying out alkali washing treatment, and carrying out ultrasonic cleaning after the treatment is completed; s5, the cleaned raw materials are fed into a heating furnace to be subjected to high-temperature heat treatment; s6, magnetic separation is repeated; and S7, further crushing into fused quartz sand of which the particle size is less than 2mm by adopting an impact crusher. According to the preparation method of the high-purity fused quartz powder, circulating pickling is adopted, the optimal pickling condition acid concentration, acid dosage, pickling time, pickling temperature and the like are selected, metal impurities are effectively removed, and the purification effect is good; repeated magnetic separation is carried out under high and low field intensities, the magnetic separation effect is good, magnetic impurities are preliminarily and efficiently removed, and the purity of the whole manufactured product is high.

The invention belongs to the field of preparation of high-purity quartz, and relates to a method for directionally removing impurity elements of pegmatite type high-purity quartz, which comprises the following steps: (1) crushing raw materials by a crusher, washing ore, grinding and grading, reselecting and floating to obtain quartz concentrate; (2) adding the quartz sand into the leachate A for constant-temperature micro-pressure leaching, and washing to obtain primary quartz sand; the leachate A is mixed acid of HF, HCl and HNO3, the concentration ratio of the HCl to the HNO3 is (3-12): 1, the concentration ratio of the HCl + HNO3 to the HF is smaller than or equal to 3, and the sum of the concentrations of the HCl, the HCl and the HNO3 is larger than or equal to 3 mol / L; (3) roasting and water quenching to obtain intermediate quartz sand; (4) adding the quartz sand into the leachate B for ultrasonic leaching, washing, and carrying out high-temperature heat treatment to obtain high-purity quartz sand; the leachate B is a mixed acid of HF and HCl, HF is 0.5-2 mol / L, and the concentration ratio of HCl to HF is less than or equal to 3. According to the method, the 4N8-grade high-purity quartz sand can be obtained, the yield is high, the process is simple, and operation is easy.

The invention discloses a wet electronic chemical separation and purification device, and particularly relates to the technical field of wet electronic chemicals, the wet electronic chemical separation and purification device comprises a transmission base, the top of the transmission base is fixedly connected with a storage bin, and the front and rear sides of the right side of the transmission base are fixedly connected with separation and purification seats respectively; by arranging the separation and purification base, the vertical plate, the push-pull plate, the filtering bin, the storage bin and the test tube rotary table, automatic and continuous treatment of raw materials is achieved, the raw materials can fully react in the purification treatment process through the design of the separation and purification base, the raw materials can be fully separated, and the raw materials can be fully purified. The purification efficiency and effect are improved, due to the structural design of a vertical plate and a push-pull plate, operation is more convenient, meanwhile, the safety of the equipment is guaranteed, and the problem that due to the fact that sodium sulfate and wet electronic chemicals cannot be well fused, the sodium sulfate and the wet electronic chemicals can be fused insufficiently, and the preliminary passivation effect is affected is solved.

The utility model discloses a device capable of improving the high purity of quartz sand. The device comprises a screening box, a feeding port is formed in the top of the screening box, a plurality of supporting legs are fixedly connected to the bottom of the side wall of the screening box, an impurity removal cavity and an adsorption cavity are formed in the screening box, and the device further comprises a separation screening assembly located in the middle of the screening box; the material beating mechanism is located at the top of the separating and screening assembly; the magnetic suction impurity removal mechanism is located in the middle of the separating and screening assembly and used for adsorbing magnetic minerals in the filtered quartz sand; according to the scheme, by arranging the magnetic suction impurity removal mechanism, tiny magnetic minerals in quartz sand can be circularly adsorbed and removed, so that the situation that the purity of the quartz sand is affected due to the fact that the tiny magnetic minerals are difficult to filter and remove is avoided, and the purpose of effectively improving the purification effect on the quartz sand is achieved; impurities adhered to the quartz sand can be slapped and dispersed, so that the purification of the quartz sand is facilitated.

The application discloses a micro-fluidic chip and a method for recovering nucleic acids with different fragment sizes. The method can realize recovery of nucleic acids with different fragment sizes by repeatedly washing and recovering magnetic beads through the micro-fluidic chip. The method can improve the overall nucleic acid recovery effect by adjusting the adding concentration of the magnetic beads and PEG salt and the washing times, and can distinguish and control the nucleic acid length, and all the nucleic acids with different fragment lengths can be obtained by continuously adjusting the concentration. Moreover, the method can realize small volume, high throughput and automation.

The invention relates to a separation and purification method in chemical production, and provides an energy-saving and efficient nitro-aromatic hydrocarbon separation and purification method. Gravity settling, alkali washing, cooling and filtering are combined, a liquid-liquid micro-mixer and cooling and filtering are used for replacing traditional tedious multi-stage neutralizing and water washing operation of a multi-kettle series connection or static mixer, impurities such as residual acid, phenols, sodium salt and water in the acidic nitro-aromatic hydrocarbon are efficiently removed, the emulsification phenomenon is avoided, and the quality of the acidic nitro-aromatic hydrocarbon is improved. And the treated material can ensure long-term stable operation of a subsequent rectification system. The method does not need a two-stage washing process in the prior art, and is low in material consumption, energy consumption and wastewater amount; the liquid-liquid mixer is used for the alkali washing process, and the alkali washing effect is remarkably improved; water and salts in the crude nitro-aromatic hydrocarbon are removed in one step in a fiber filter element cooling and filtering mode, and the separation efficiency is high; the whole set of separation and purification device is a totally-closed system device, is small in occupied area and simple to operate, and the purification effect is remarkably improved compared with a conventional process.

The invention discloses a method for purifying an adrenocorticotropin analogue, which comprises the following steps of: removing impurities which have charge difference and polarity difference with the adrenocorticotropin analogue by using a specific chromatographic filler through one-step ion exchange chromatography and one-step reversed-phase chromatography, and purifying the adrenocorticotropin analogue to obtain the purified adrenocorticotropin analogue. The technical effect of efficiently purifying the corticotropin analogue is realized. The purity of the purified adrenocorticotropin analogue can reach 99.73%, the proportion of a single impurity is only 0.15%, and the recovery rate is increased by about 33% compared with the prior art. The method has the advantages of good purification effect, low production cost, environmental friendliness, simplicity and convenience in operation and the like.

The application discloses a method for preparing high-purity tellurium dioxide powder from waste tellurium dioxide target material, comprising the following steps: step one, crushing the waste tellurium dioxide target material to obtain tellurium dioxide pre-crushed material; step two, ball-milling the tellurium dioxide pre-crushed material and drying to obtain tellurium dioxide powder; and step three, purifying the tellurium dioxide powder to obtain high-purity tellurium dioxide powder. 131 The application solves the problems of traditional powderization process, such as serious powder agglomeration, wide particle size distribution, easy introduction of impurities and poor industrial applicability, and the prepared powder can be directly applied to the production of tellurium dioxide target material, and the method can also be applied to the preparation of tellurium dioxide single crystal, infrared acousto-optic devices and electronic component materials, and has excellent industrial application prospect.

The utility model discloses a hydrogen purification device, which relates to the technical field of hydrogen purification and comprises a purification cylinder for gas circulation, a gas inlet is arranged at the top of the purification cylinder, and a gas outlet is arranged at the bottom of the purification cylinder. A hydrogen separation membrane used for purifying hydrogen in gas in the gas circulation process is arranged on the purification barrel, a partition plate is fixedly installed in the purification barrel, a gas passing opening is formed in the side wall of the purification barrel in a penetrating mode, and an exhaust pipe communicated with the interior of the purification barrel is fixedly installed on the top wall of the purification barrel; an upper baffle is fixedly installed on the upper portion of the outer wall of the purification cylinder, a lower baffle is slidably connected to the lower portion of the outer wall of the purification cylinder, a sleeve is arranged between the upper baffle and the lower baffle, and the hydrogen separation membrane is installed between the inner wall of the sleeve and the outer wall of the purification cylinder; and the interior of the purification barrel is divided into an upper chamber and a lower chamber which are independent from each other through a partition plate. The hydrogen separation membrane solves the problem that the utilization efficiency of the hydrogen separation membrane is low.

The utility model discloses an adsorption tower, adsorption system and hydrogen production machine, wherein the adsorption tower comprises: a tower body having an adsorption chamber for filling adsorbent, the bottom of the tower body being provided with a first vent hole, the top of the tower body being provided with a second vent hole, the first vent hole, the adsorption chamber and the second vent hole being communicated in sequence; the distributor comprises a sieve plate and a splitter plate, the sieve plate is provided with a plurality of sieve holes and arranged at the bottom of the adsorption cavity, and the splitter plate is arranged on the side, facing the first vent holes, of the sieve plate, so that gas entering from the first vent holes is dispersed by the splitter plate and then enters the adsorption cavity from the sieve holes of the sieve plate. According to the utility model, the distributor is arranged to disperse gas, so that the gas can be prevented from directly impacting on the adsorbent to damage the adsorbent; meanwhile, the gas is dispersed and then is in contact with the adsorbent after being shunted by the sieve pores, so that the gas can be in full contact with the adsorbent, the gas is prevented from passing through the adsorbent without being fully purified, and the purification effect of hydrogen is improved.

The invention discloses a method for purifying XVII type collagen. The method comprises the following steps: firstly, balancing a boric acid affinity chromatography column by using an alkaline solution; secondly, balancing again after loading the sample; thirdly, washing impurities with alkaline leacheate; and finally, eluting the XVII type collagen from the boric acid affinity filler by using a slightly acidic eluent. The purification effect on the XVII type collagen is good, and the purity is higher than 95%; moreover, the purification method provided by the invention is simple to operate and relatively low in cost, and has a good application prospect.

The invention relates to the technical field of quartz sand cleaning, in particular to a cleaning agent for cleaning quartz sand and a production process of the cleaning agent. The cleaning agent is prepared from the following raw materials in parts by weight: 3 to 20 parts of sodium dodecyl sulfate, 2 to 7 parts of sodium aliphatate, 8 to 18 parts of sodium carbonate, 1 to 7 parts of anionic cellulose ether, 3 to 15 parts of methylene bis-naphthalene sulfonate, 15 to 30 parts of soap powder, 15 to 35 parts of sodium silicate and 15 to 25 parts of polyphosphate. The cleaning agent has the beneficial effects that the purification effect is remarkable, the cleaning agent can effectively remove impurities such as iron and oxides on the surface of quartz sand, and the purity of the quartz sand is improved; the cleaning agent is environment-friendly in component, free of pungent smell and low in waste liquid treatment difficulty; meanwhile, the cleaning agent dosage is small, and the production cost is low; the production process is simple, automatic control is easy to realize, and the production efficiency is improved; the quartz sand cleaning agent is suitable for cleaning various types of quartz sand and has a wide application prospect.

The application belongs to the technical field of biological medicine, and particularly relates to a polypeptide degradation agent for targeted degradation of CD26 and a preparation method and application thereof. The polypeptide degradation agent is obtained after coupling of a tetrapeptide and lenalidomide. The amino acid sequence of the tetrapeptide is any one of SEQ ID NO. 1 and SEQ ID NO. 2. The polypeptide degradation agent can specifically target and degrade DPP4, i.e. CD26, but cannot degrade DPP4 isozymes such as DPP7, DPP8 and DPP9, and thus has high selectivity. In addition, the polypeptide degradation agent has small molecular weight, one end is a natural short peptide, has good tissue compatibility, can quickly degrade target proteins in 6 hours, and thus has good tissue permeability.

The utility model discloses a methanol production purification device which comprises a shell, a driving purification mechanism and a filtering disassembly and assembly mechanism, the driving purification mechanism is arranged in the shell and comprises a partition plate, the partition plate is installed on the inner wall of the shell, the left side of the partition plate is fixedly connected with the inner wall of the shell through a partition block, and the filtering disassembly and assembly mechanism is arranged on the inner wall of the shell. And the filtering disassembly and assembly mechanism is arranged in the shell. According to the methanol purification device disclosed by the utility model, through mutual cooperation of the partition plate, the partition block, the servo motor, the fixed shaft, the partition block, a through hole, a heating plate, a guide pipe, a heat conduction pipe, a fixed plate, a refrigeration sheet, a water temperature sensor, an alarm, a filter screen, a top block, a connecting block, a pull plate, a fixed groove, a fixed rod, a sliding block, a limiting plate and a buffer spring, the purification effect is improved, so that methanol can be uniformly heated; in addition, the filter screen can be regularly detached to be cleaned and maintained according to requirements, so that the practicability is improved.

The application provides a pickling purification method of porous carbon for silicon-carbon negative electrode materials and a product thereof, and belongs to the technical field of battery material preparation. The method overcomes the defects of poor purity and long process flow of the existing pickling method. The production method comprises the following steps: crushing carbonization raw materials to 20-50 meshes, and then performing physical activation. The method further comprises the steps of "blowing and stirring cleaning" and "belt rinsing while simultaneously performing vacuum exhaust and controlling the water content to be 60%". The porous carbon is deeply and efficiently purified, so that the iron content and ash content of the porous carbon are reduced to a very low level (Fe<30ppm, ash content<0.2%), and the high-pore structure (iodine value≥1600mg / g) of the porous carbon is maintained. The unique blowing and stirring method has smaller shearing force on the carbon skeleton, and better protects the microstructure of the porous carbon. The belt rinsing is continuously operated, and has high automation degree, and is suitable for large-scale industrial production. The porous carbon product prepared by the method has very high purity and high specific surface area, and meets the needs of high-end lithium ion batteries.

The utility model relates to the field of raw material pretreatment devices, and discloses a C4 raw material pretreatment device which comprises a base, the upper portion of the base is fixedly connected with a material storage box, the right side of the upper portion of the material storage box is provided with a backflow assembly, the left side of the upper portion of the base is fixedly connected with an installation frame, and the upper portion of the front side of the installation frame is fixedly connected with a control panel. A distillation box is fixedly connected to the upper part of the mounting frame, a feeding pipe is fixedly connected to the upper part of the left side of the distillation box, a first control valve is fixedly connected to the outer side of the feeding pipe, a distillation assembly is arranged in the distillation box, a backflow assembly comprises a water pump, a water pumping pipe and a water conveying pipe, and the water pump is fixedly connected to the right side of the upper part of the storage box. According to the C4 raw material pretreatment device disclosed by the utility model, through the matching of the water pump, the water pumping pipe, the water conveying pipe, the cone, the U-shaped heating rod, the material guide pipe and the like, the C4 raw material can be repeatedly distilled by the C4 raw material pretreatment device, so that the purification effect of the C4 raw material is improved.

The invention relates to a sealing oil purification system which comprises an oil conveying pipeline, an oil inlet of the oil conveying pipeline is communicated with an oil source, and an oil outlet of the oil conveying pipeline is communicated with a generator system; the vacuum oil tank is communicated with the oil conveying pipeline, negative pressure is formed in the vacuum oil tank, and the vacuum oil tank is used for separating gas in the sealing oil; the separation device is communicated with the oil conveying pipeline, is arranged at the upstream of the vacuum oil tank, and is connected with a first vacuum pump; and the communicating pipeline is used for allowing gas to flow and is communicated with the top of the separating device and the top of the vacuum oil tank. The sealing oil purification system can convey high-purity sealing oil to the generator system, so that the purity of hydrogen in the generator system is guaranteed, and the sealing oil purification system is good in economical efficiency and high in safety.

The utility model discloses glacial acetic acid purification equipment and relates to the technical field of glacial acetic acid purification. According to the glacial acetic acid purification equipment base, four supporting legs are fixedly connected to the upper surface of the base, a distillation flask is fixedly connected to the upper ends of the four supporting legs, and an accelerated purification mechanism is arranged on the distillation flask; the accelerated purification mechanism comprises a liquid inlet pipe, a steam pipe, a motor, a vertical shaft, a heating seat, a mixing rod, a first rotating hole, a second rotating hole, a connecting pipe, a heating rod, a reset spring, a mounting block, a pushing plate and a rotating sliding plate, and the steam pipe is fixedly connected to the upper surface of the distillation flask. And the mixing rod rotates to stir a mixture in the distillation flask, so that the mixture is mixed more uniformly, and the mixture in the distillation flask is heated more uniformly and efficiently, thereby ensuring the purification efficiency and quality of glacial acetic acid.

The invention relates to the technical field of chemical manufacturing, in particular to a phenylenediamine rectification purification tower. According to the technical scheme, the device comprises a rectifying section and a stripping section fixed to the lower portion of the rectifying section, a rectifying plate structure is arranged on the inner wall of the rectifying section, and a filter opening mechanism is arranged at the top end of the rectifying plate structure and comprises a plurality of fixed bases fixed to the top end of the rectifying plate structure; the top ends of the multiple fixed bases are fixedly connected with steam guide blocks, the outer walls of the multiple steam guide blocks are slidably connected with airflow guide structures, the top ends of the multiple steam guide blocks are provided with air guide ports in a penetrating manner, the stripping section comprises a stripping tank, and the inner wall of the stripping tank is provided with a filtrate mechanism and a filter guide mechanism. According to the phenylenediamine rectification purification tower, the purification rate of phenylenediamine is increased, repeated purification and rectification are not needed any more, time is saved, and the phenylenediamine rectification purification tower has the functions of being better in phenylenediamine purification effect and higher in efficiency.

The invention belongs to the technical field of rice bran wax purification, and particularly relates to rice bran wax purification equipment which comprises a centrifugal separation box, the upper end of the centrifugal separation box is hermetically covered with a box cover, and a first motor is fixedly mounted in the center of the lower end of the centrifugal separation box; the output end of the first motor penetrates through the bottom of the centrifugal separation box and is coaxially and fixedly connected with a centrifugal disc in the centrifugal separation box. The rice bran wax purification process adopts the rice bran wax purification equipment for purification, and comprises the following steps: S1, putting the wax paste to be purified and the ternary azeotrope into the stirring tank according to a certain proportion, and uniformly stirring and mixing at a certain temperature through the second motor and the stirring rod. The device has the advantages that the centrifugal layering work can be quickly and effectively completed, the centrifugal efficiency is improved, the subsequent treatment and procedure continuity are ensured, and the purification effect and efficiency are greatly improved.

The invention discloses a method for separating and purifying gastrodin in fermentation liquor, which comprises the following steps: (1) adding low-carbon alcohol into the fermentation liquor, standing and precipitating to obtain alcohol precipitation liquid; (2) filtering the alcohol precipitation liquid in the step (1) by using a filter membrane, collecting permeate liquid, and evaporating to obtain gastrodin clear liquid; (3) loading the gastrodin clear liquid obtained in the step (2) to a macroporous adsorption resin chromatographic column, eluting with pure water and an ethanol water solution in sequence, and collecting an ethanol water solution section eluent; and (4) evaporating, concentrating and drying the ethanol aqueous solution section eluent in the step (3) to obtain gastrodin. According to the method, extraction and repeated crystallization are not needed, the operation steps are simple, the gastrodin can be separated and purified only through one-time column chromatography, the purity of the finally obtained gastrodin is 95% or above, and the yield is 98% or above.

The application relates to a cooling system for NMP rectification, which comprises a condenser, a cooling tower, a lithium bromide cooling unit and a cooling water storage tank, the lithium bromide cooling unit is internally provided with an evaporation area, a liquefaction area and a throttle valve, rectification tower steam condensate outside the lithium bromide cooling unit passes through the evaporation area and is connected with the cooling tower, a circulating water pool is arranged at the bottom of the cooling tower, the cooling tower and the circulating water pool are both connected with the liquefaction area, a feeding port and a discharging port are arranged on the condenser and used for conveying NMP materials, a liquid inlet and a liquid outlet are arranged on the condenser, the liquid outlet is connected with the throttle valve inside the lithium bromide cooling unit, a liquid inlet pipe is arranged between the liquid inlet and the throttle valve, and the cooling water storage tank is arranged on the liquid inlet pipe. The application can improve the purification effect of NMP recovery.

The invention discloses extraction and purification equipment and method for liver-protecting lonicera caerulea polysaccharide, and relates to the technical field of extraction technology.A crushing and cleaning mechanism is sequentially arranged in a box from top to bottom and comprises an extrusion filter plate, a rotary extrusion cleaning arm and a turnover plugging assembly, and a through groove is formed in the extrusion filter plate in the radial direction; the overturning and blocking assembly is located at the bottom of the extrusion filter plate and blocks the through groove through overturning; the connecting assemblies are located on the two sides of the reversing plate; the upper ends of the connecting rods are fixedly connected with the extrusion filtering plate; one end of the rotating shaft is rotationally connected to the middle of the two sides of the reversing plate, and the other end of the rotating shaft is rotationally connected with the connecting rod on the same side; the upper ends of the supporting rods are hinged to the ends of the overturning plugging assemblies on the same side. One end of each short rod is hinged to the lower end of the corresponding supporting rod on the same side, and the other end is fixedly connected with the rotating shaft on the same side; wherein the turnover plugging assembly rotates to change directions, drives a reversing plate to change directions and incline through a supporting rod and a short rod, and is communicated with juice and pomace extraction mechanisms in the extraction mechanism in sequence.

The invention discloses a preparation and purification method of carboxymethyl chitin, which comprises the following steps: crushing a proper amount of blocky chitin raw material, adding the crushed blocky chitin raw material into an alcohol solution, fully stirring to fully swell the chitin, adding a pre-prepared alkali solution into the solution, carrying out alkalization reaction, adding pre-prepared carboxylation reaction liquid in batches, and carrying out solid-liquid separation to obtain the carboxymethyl chitin. The preparation method comprises the following steps: fully carrying out carboxymethylation reaction, standing, removing supernate, filtering to obtain a crude carboxymethyl chitin product, carrying out alkali-assisted alcohol precipitation, adding the precipitate into a low-concentration alcohol solution, adjusting the pH value to be neutral by using acid in a stirring state, adding a high-concentration alcohol solution, uniformly stirring, filtering, removing supernate and the like. According to the method, a traditional heterogeneous reaction system preparation process is optimized, the alkali-assisted alcohol precipitation and step-by-step elution technology is utilized for purification treatment, the dosage of ethanol is saved, the problems that in the prior art, carboxymethyl chitin is high in purification cost, high in salt content and the like are solved, and the process is simple, efficient, low in cost, good in purification effect and suitable for industrial production.