The invention belongs to the technical field of medicines, and particularly relates to a
uremia clearing
capsule and a preparation method thereof. The
uremia clearing dry paste
powder comprises the following raw materials in parts by weight: 60-80 parts of
uremia clearing dry paste
powder, 20-40 parts of a filling agent and 0.005-0.02 part of a lubricating agent, the filling agent comprises
corn starch,
pregelatinized starch and
mannitol. The preparation method of the
capsule comprises the following steps: mixing the uremia clearing dry paste
powder, the filling agent and part of the lubricating agent, performing dry
granulation, mixing granules and the remaining lubricating agent, and filling to prepare the
capsule. By selecting the filling agent, the hygroscopicity of the content can be effectively reduced, and the stability of the capsule is improved; moreover, the dry paste powder can be successfully tableted and granulated by adopting a dry
granulation process, a roller is not adhered, the granule forming rate is high, and a complex wet
granulation process is avoided. And the
process conditions of the dry paste powder are optimized, and the dry paste powder is prepared into capsules, so that the compliance of patients is improved.