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Sleep aid

A technology for sleep improvers and aroma components, applied in the formulation of perfume preparations, drug combinations, plant/algae/fungus/moss components, etc. Wake-up time, sleep quality improvement, effect of improving sleep quality

Pending Publication Date: 2021-04-30
MITSUI NORIN
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, aroma components extracted from natural substances have the following problems: the composition of aroma components tends to change depending on the origin of raw materials, manufacturing methods, etc., and stable sleep effects cannot be obtained

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0133] Regarding the aroma component 3, the sleep improvement effect was investigated in detail.

[0134]

[0135] 20 women aged 30 to 45 who were dissatisfied with sleep were used as test subjects. In the test product A, ion-exchanged water was used as a placebo. The Darjeeling tea fragrance of the fragrance component 3 was used for the test product B. The test was performed by a method of diffusing and sucking each test product with an ultrasonic diffuser (manufactured by Ryopin Plan Co., Ltd., ultrasonic diffuser 11SS). Each test product was diffused and inhaled for a total of 3 hours from 1 hour before going to bed to 2 hours after going to bed. Conduct the test according to the following schedule and analyze the test results.

[0136] The test design was set as a cross-test between 1 and 2 groups using two phases of 2 test articles (A and B).

[0137] In phase 1 (time period I) (days 1 to 7), group 1 used test article A and group 2 used test article B; in phase 2 (t...

Embodiment 2

[0167] The sleep effect of a sleep-improving agent containing dehydrolinalool as an aroma component was investigated in detail.

[0168]

[0169] 16 women aged 30 to 45 who were dissatisfied with sleep were used as subjects. In the test product A, ion-exchanged water was used as a placebo. As the test product B, a sample (100 ppm of dehydrolinalool) obtained by dissolving dehydrolinalool (manufactured by Soda Fragrance Co., Ltd.) in ion-exchanged water was used. The test method and analysis method were carried out in the same manner as in Example 1.

[0170] In addition, in , in Example 1, it was divided into a high group with a high stress score before the test and a low group with a low stress score However, in Example 2, the evaluation was performed without dividing into such groups.

[0171]

[0172] exist Figure 11 The composite PSQI scores (average of 16 subjects) of all subjects before the test, after the placebo-provided period and after the test article B-pr...

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PUM

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Abstract

The problem to be solved by the present invention is to provide a sleep aid that contains aroma components extracted from natural sources and that yields a stable soporific effect. Provided is the sleep aid containing hotrienol as an active ingredient, or containing one or more types of tea-derived aroma components. In particular, the aroma component is constituted by (A) a citrusy floral aroma component, (B) a sweet floral aroma component, (C) a rich floral aroma component, (D) a woody aroma component, (E) a green aroma component, and (F) a cool aroma component. When absorbed transdermally, intranasally, or orally, the sleep aid is capable of increasing sleep quality and ameliorating insomnia symptoms.

Description

technical field [0001] The present invention relates to a sleep improving agent, which contains dehydrolinalool as an active ingredient, or contains one or more aroma components derived from black tea, and more specifically, relates to a sleep improving agent, which has A combination of a specific ratio of a specific citrus floral aroma component and a specific cooling aroma component among aroma components derived from black teas. Background technique [0002] In recent years, the number of people with sleep disorders has been increasing, and among them, it is reported that 1 in every 5 Japanese suffers from insomnia symptoms. Various treatments have been carried out to ensure sufficient quality and quantity of sleep, but there are cases where natural sleep cannot be obtained through drug therapy, and long-term use tends to be avoided due to concerns about side effects. Therefore, studies have been conducted on the improvement of sleep quality using ingredients derived fro...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/82A23L2/00A23L2/52A23L33/105A61K8/31A61K8/34A61K8/35A61K8/36A61K8/37A61K8/49A61K8/9789A61K31/01A61K31/015A61K31/045A61K31/11A61K31/12A61K31/121A61K31/122A61K31/19A61K31/22A61K31/341A61K31/618A61P25/20A61P43/00A61Q13/00
CPCA23L33/105A61K31/015A61K8/9789A61K31/22A61K31/618A61K31/01A61Q13/00A61K8/49A23L2/52A61K36/82A61P43/00A61K31/19A61K8/31A61K8/34A61K31/11A61K8/35A61K31/12A61K8/36A61K8/37A23L2/00A61P25/20A61K31/121A61K31/341A61K31/045A61K31/122
Inventor 大野敦子
Owner MITSUI NORIN
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