The invention discloses an electric heating liquid mosquito-repellent incense with sweet marjoram fragrance and a preparation method thereof. The preparation method comprises the following steps: stirring, dispersing and uniformly mixing the following materials in parts by weight: 40-60 parts of ethanol, 10-30 parts of butyl butyrate, 10-15 parts of traditional Chinese medicine mosquito-repellent purified solutions, 18-19 parts of eucalyptus oil, 1-2 parts of isopropyl myristate, 10-15 parts of fatty alcohol-polyoxyethylene ether sodium sulfate and 0.1-0.3 part of sodium benzoate, and then filling into a bottle; inserting a volatilizing rod made from fibers into the bottle, and heating so as to volatilize to repellent mosquitos. The electric heating liquid mosquito-repellent incense disclosed by the invention is high in safety, not only is capable of effectively repelling the mosquitoes, but also achieves certain inhibition and killing effects on multiple pathogens and fungi, such as staphylococci, mycobacterium tuberculosis, pseudomonas aeruginosa, gram-negative bacteria and gram-positive bacteria, is fragrant in smell, moderate in property, fresh and capable of tranquilizing mind and relieving pressure, can effectively improve the sleep and enhance the sleep quality and is suitable for people of all ages.