The invention relates to a selenium-enriched earthworm breeding method. The method comprises the following steps of 1, straw treatment, wherein straw is smashed, and is placed into a sealing device together with ammonium hydroxide, microwave softening is conducted, and softening is finished to obtain softened straw; 2, preparation of a breeding medium, wherein animal dung, the softened straw, a bacteria agent and sodium selenite are mixed proportionally, fermentation and decomposition are conducted, after decomposition is finished, earthworm phagostimulant is added, and even mixing is conducted to obtain the earthworm breeding meidum; 3, breeding management, wherein the earthworm breeding medium is flatly laid on a breeding bed, the phagostimulant is sprayed on the surface of the breeding bed, earthworm larvae are added, breeding is conducted, the moisture content of the earthworm breeding medium is maintained, the same earthworm breeding medium is added every 5-10 days, the phagostimulant is sprayed on the surface of the earthworm breeding medium, and breeding is conducted for 45-50 days; 4, earthworm harvesting. The selenium-enriched earthworm breeding method has the advantages of being high in growing speed, high in yield and good in selenium-enriched effect.