346 results about "Methyl butyrate" patented technology

The invention relates generally to the field of industrial microbiology and butanol production. More specifically, the invention relates methods of reducing 2,3-dihydroxy-2-methyl butyrate (DHMB) in butanol production. DHMB can be reduced by inhibiting the reduction of acetolactate to DHMB, for example, by knocking out enzymes that catalyze the reduction or by removing DHMB during or after fermentation. Yeast strains, compositions, and methods for reducing DHMB and increasing butanol yield are provided.

Compositions and lures are described which provide vapor blends of acetic acid and one or more compounds selected from the group consisting of isobutanol, racemic 2-methyl-1-butanol, S-(-)-2-methyl-1-butanol, 2-methyl-2-propanol, heptyl butyrate, and butyl butyrate which function as highly effective attractants for yellowjacket wasps and paper wasps. By attracting wasps to traps or baits, the chemical attractants provide a means for detecting, surveying, monitoring, and controlling the wasps.

There is provided in one embodiment of the invention an electrolyte for use in a lithium ion electrochemical cell. The electrolyte comprises a mixture of an ethylene carbonate (EC), an ethyl methyl carbonate (EMC), an ester cosolvent, and a lithium salt. The ester cosolvent comprises methyl propionate (MP), ethyl propionate (EP), methyl butyrate (MB), ethyl butyrate (EB), propyl butyrate (PB), or butyl butyrate (BB). The electrochemical cell operates in a temperature range of from about −60 degrees Celsius to about 60 degrees Celsius. In another embodiment there is provided a lithium ion electrochemical cell using the electrolyte of the invention.

The invention provides polymer microspheres for high temperature hypersalinity reservoir deep profile control and a preparation method thereof. In the method, based on the method that photopolymerization is used to prepare the polymer microspheres, heat and salt resistance polymer materials such as sodium 3-acryloylamino-3-methyl butyrate, 2-acryloylamino-2-methylpropane sulfonic acid, acrylamide monomer and the like and water-soluble anionic monomer are adopted and dispersant and cross-linking agent are added as so to form oil-water mixed emulsion in the mixed medium of surfactant and solvent; then initiator is decomposed by ultraviolet through photopolymerization under controllable temperature so as to initiate emulsion polymerization and 50-500nm of microspheres are formed. The invention utilizes the ability of microspheres that microspheres can be dispersed in arbitrary concentration and injected in the water and can gradually swell after entering in depth of the formation to plug the pore throat so as to effectively plug the high permeable strip of the formation, expand the water swept volume, significantly increase crude oil recovery of water flooding reservoir and is applicable to high temperature hypersalinity reservoir deep profile control.

The invention discloses an aqueous electrolyte solution of a secondary lithium ion battery with ferric phosphate considering as the positive material and with both the high temperature performance and the low temperature performance. The aqueous electrolyte solution comprises LiPF6 lithium salt, an organic solvent and a film-forming additive, and is characterized in that the electrolyte solution further comprises high temperature additive; the organic solvent is composed of one or a plurality of carbonic esters and one or more carboxylic esters with low melting point and high boiling point. The carboxylic esters with low melting point and high boiling point are selected from one or a combination of methyl butyrate, ethyl butyrate, propyl butyrate and butyl acetate. The high temperature additive is 1, 3- propane sultone and 1, 4- butane sultone. The electrolyte solution is used for maintaining both the circulation performance in a high temperature state and the low temperature laying performance of the secondary lithium ion battery with the ferric phosphate lithium as the positive material.

Embodiments of the invention relate to a composition for controlling a target pest, wherein the composition includes at least two active ingredients selected from the group consisting of thymyl acetate, linalyl acetate, amyl butyrate, anise star oil, black seed oil, p-cymene, geraniol, isopropyl myristate, d-limonene, linalool, lilac flower oil, methyl salicylate, alpha-pinene, piperonal, piperonyl alcohol, tetrahydrolinalool, thyme oil white, thyme oil red, thymol, vanillin, and winter-green oil, wherein the composition causes synergistic control of the target pest.

The invention relates to a biological preparation method of 3-amino-4-(2,4,5-trifluorophenyl)methyl butyrate. According to the biological preparation method, 3-carbonyl-4-(2,4,5-trifluorophenyl)methyl butyrate is used as a substrate; under the condition that a biocatalyst, a cofactor, an amino donor and a cosolvent exist, the substrate performs the reaction to generate a target product 3-amino-4-(2,4,5-trifluorophenyl)methyl butyrate; the biocatalyst is recombination aminopherase; and the reaction is carried out in water-phase buffer solution with the pH of 6.0 to 9.0. The biological preparation method realizes that 3-carbonyl-4-(2,4,5-trifluorophenyl)methyl butyrate is converted into 3-amino-4-(2,4,5-trifluorophenyl)methyl butyrate by adopting the recombination aminopherase for the first time; compared with a conventional chemical method, the biological preparation method has low energy consumption, is simple and convenient to operate, generates a small number of by-products; and moreover, the product has high optical activity.

The invention relates to a lithium iron phosphate battery with lithium ion battery electrolyte suitable for ultralow-temperature charging and discharging. The lithium ion battery electrolyte comprises lithium salt, a multi-element organic solvent and additives, wherein the additives comprise a low-melting-point additive, a film forming additive and a high-temperature additive; the multi-element organic solvent contains at least three of ethylene carbonate, diethyl carbonate, dimethyl carbonate, methyl ethyl carbonate, propylene carbonate and butylene carbonate; the low-melting-point additive contains at least one of 4-methyl-1,3-dioxolane, methyl acetate, methyl propionate, methyl butyrate, ethyl butyrate, propyl butyrate and butyl acetate; the high-temperature additive is at least one of methyl ester, di-n-propyl carbonate and 1,3-propane sultone. The lithium iron phosphate battery with the electrolyte can charge and discharge at an ultralow temperature and in a high-temperature environment, and is stable in performance and long in recycling life.

The invention provides a sports beverage which contains 0.1-20% of beta-hydroxy-beta-methyl butyrate (HBM). The sports beverage of the invention can be prepared into a liquid beverage capable of being directly drunk, a thickening beverage capable of being drunk after being diluted and a solid beverage capable of being drunk after being made. The sports beverage containing the HMB has the function of accelerating human body muscle synthesis, effectively covers the undesirable flavour of the HMB and is convenient for people taking exercise.

The invention provides a special dietary food suitable for old people with sarcopenia to eat. The special dietary food is characterized by being prepared from the following components in parts by weight: 3-53.5 parts of proteins, 1-2 parts of calcium beta-hydroxy-beta-methyl butyrate, 2-5 parts of dietary fibers, 0.8-2 parts of fatty acid, 0.2-1.3 parts of compound vitamins and 1.5-2 parts of composite mineral substances. The food has the advantages of simple and convenient production process, safety in eating, good mouth feel and no side effect, can be used for delaying the sarcopenia of the old people, has prevention and improvement effects and is suitable for people to use for a long period.

The invention discloses a preparation method of sitagliptin, comprising the following steps: reacting 2, 4, 5-trifluoro-phenylacetic acid with malonic cyclo (sub) isopropyl ester; reacting 3-oxo-4-(2, 4, 5-trifluorophenyl) methyl butyrate with ammonium acetate; reacting 3-amino-4-(2, 4, 5-trifluorophenyl) methyl crotonate with hydrogen; performing hydrolysis reaction to (R)-3-amino-4-(2, 4, 5-trifluorophenyl) methyl butyrate; and reacting (R)-3-amino-4-(2, 4, 5-trifluorophenyl) butyric acid with 3-(trifluoromethyl)-5, 6, 7, 8-tetrahydro-[1, 2, 4] triazol [4, 3-a] pyrazine hydrochloride to obtain sitagliptin. According to the invention, EE value greater than 90% is obtained through high-efficiency catalytic hydrogenation; sitagliptin is prepared by only five steps; yield is higher; technical conditions are mild; operations are simple; cost is low; and yield and purity of products are high.

The invention relates to a quantum-dot light-emitting diode and a preparation method therefor. The structure of the light-emitting diode sequentially comprises an anode, a hole injection layer, a hole transmission layer, a quantum-dot light-emitting layer, an electron transmission layer, and a cathode. The electron transmission layer is a [6, 6]-phenyl-C61-methyl butyrate PCBM film. The preparation method is a spin coating method. According to the invention, the electron transmission layer can effectively improve the exciton recombination probability and the luminous efficiency of a device. Meanwhile, the quantum-dot light-emitting diode is a typical sandwich structure, and the spin coating method is employed for layer-by-layer assembly. The preparation method is simple and feasible, facilitates the preparation of a large-area light-emitting device, and is widely used in the field of quantum-dot light-emitting diodes.

A pouch-type lithium secondary battery includes an electrode assembly having an anode made of carbon material capable of occluding or emitting lithium ions, a cathode made of lithium-containing oxide, and a separator interposed between the cathode and the anode for electrical insulation therebetween; a pouch-type case made of sheet to provide a space receiving the electrode assembly; and a non-aqueous electrolyte injected into the electrode assembly. The non-aqueous electrolyte is a non-linear carbonate-based non-aqueous electrolyte including a lithium salt, (a) a cyclic carbonate compound, and (b) a linear ester compound selected from propionate-based compound, methyl butyrate, and propyl acetate, or their mixtures. During LiPF6 IM dissolution, the non-aqueous electrolyte has an ion conductivity of 9 mS / cm or above at about 23° C. This pouch-type lithium secondary battery ensures excellent high-rate discharging characteristics and solves swelling problems associated with a pouch-type lithium secondary battery.

The invention discloses a pre-separation method of C5 diene for distilling off methyl butane for two times; two rectifying towers are used for distilling off methyl butane in C5 for two times, whereinthe first distilling is carried out before thermal dimerisation reaction, and the second distilling is carried out after the thermal dimerisation reaction the method comprises four steps: (1) pre-dehydrogenation; (2) distilling off the methyl butane for the first time; (3) thermal dimerisation reaction; (4) distilling off the methyl butane for the second time. Compared with the prior art, the method has the advantages that: the methyl butane is respectively distilled off before and after the thermal dimerisation reaction, the disadvantages that the methyl butane has large loss in the pre thermal dimerisation reaction and the content of cyclopentadiene in methyl butane material flow is hard to control in the latter thermal dimerisation reaction are overcome, thereby better realizing to fully recovering the methyl butane and to effectively control the content of the cyclopentadiene in methyl butane material flow.

The invention discloses recombinant transaminase as well as a preparation method and application of the recombinant transaminase. An amino acid sequence of a high-activity recombinant transaminase mutant is as shown in SEQ ID NO.2 and a coding gene is as shown in SEQ ID NO.1. The method for preparing the recombinant transaminase compries the steps of fermenting and cultivating a gene engineering bacterium containing the coding gene, and collecting and preparing the recombinant transaminase. The recombinant transaminase is applied to asymmetric synthesis of a chiral amine compound, and particularly is applied to synthesis of a sitagliptin midbody (R)-3-amino-4-(2,4,5-trifluoromethyl phenyl)-methyl butyrate. The related transaminase has excellent stereoselectivity, regioselectivity and catalytic activity, the catalytic reaction is mild, the reaction conversion rate and the yield of a product are high, and the recombinant transaminase has relatively good application prospect.

The invention discloses pear essence. The pear essence mainly comprises the following components: 95-97.5% of ethyl alcohol, 0.5-1% of ethyl butyrate, 0.2-0.7% of ethyl acetate, 0.2-0.7% of ethyl propionate, 0.1-0.5% of ethyl-2-methyl butyrate, 0.1-0.5% of butyl acetate, 0.1-0.6% of isoamyl acetate, 0.1-0.5% of ethyl hexanoate, 0.1-0.5% of hexenyl acetate and 0.1-0.7% of methyl 3-methylthiopropionate. Accordingly, the invention also discloses a preparation method of the pear essence. The preparation method of the pear essence comprises the steps of sequentially adding main ingredients of the pear essence in proportion, uniformly mixing and ripening, thus the pear essence product is obtained. By adopting the preparation method of the pear essence, the pear essence has strong fruit juice taste and sufficient characteristic fragrance and can reserve natural flavour of natural pear juice; the pear essence belongs to a beverage product, and reality, smoothness and fragrance of beverage taste can be obviously enhanced.

The invention provides a preparation method of levetiracetam (I). The method comprises the steps that racemization 2-halogenated butyric acid methyl ester which is in low in cost and easy to obtained is used as a raw material, a biological enzyme method is adopted to synthesize key chiral intermediate (R)-2-halogenated butyric acid methyl ester, the intermediate is subjected to ammonolysis and cyclized with 4-chlorobutyryl chloride, and finally the levetiracetam is obtained. The chiral center is built by the adoption of the enzyme asymmetric catalytic technology, a reaction path is directly reduced to three steps, the comprehensive yield is high, and the cost is low. Compared with a chemical catalyst, a biological enzyme catalyst has the advantages of being high in enantioselectivity and regioselectivity and low in energy consumption, producing few by-products and the three wastes, and the like.

A bulk heterojunction-type organic photovoltaic cell, i.e., BHJ solar cell, has a photoelectric conversion layer containing a mixture of a donor domain and an acceptor domain. The donor domain contains a polymer as a donor (photoelectric conversion material), and the polymer is obtained by reaction of a polyphenylene having a structural unit selected from moieties represented by the following general formulae (1) to (3). For example, the acceptor domain contains phenyl-C61-butyric acid methyl ester (PCBM) as an acceptor. R1 to R8 in the general formulae (1) to (3) independently represent a hydrogen atom, an alkyl group, or an alkoxy group.

The invention provides a preparation method of a cathode and anode-modified perovskite solar cell. The method comprises the following preparation steps: dissolving methyl ammonium iodide and lead chloride into dimethyl formamide to prepare a perovskite precursor solution; dissolving metal nano-particles into ethanol, mutually dissolving with PEDOT:PSS, carrying out processing on a substrate and then carrying out annealing to obtain a cured anode modifying layer; processing the perovskite precursor solution on the anode modifying layer, and then carrying out annealing to obtain a curved photosensitive layer; processing [6,6]-phenyl-C61-methyl butyrate on the photosensitive layer to obtain an electron transport layer; processing an organic material on the electron transport layer to obtain a cathode modifying layer; and processing a cathode electrode on the cathode modifying layer to obtain the cathode and anode-modified perovskite solar cell. The prepared cathode and anode-modified perovskite solar cell is high in energy conversion efficiency and good in photovoltaic characteristics.

The invention belongs to the field of producing hydrogen by carrying out photocatalysis decomposition on water with visible light and particularly relates to an organic semiconductor visible light photocatalyst with a membrane structure and a preparation method and application thereof. The visible light photocatalyst consists of the following three layers of membranes: a perylene diimide derivative membrane layer serving as a first layer; a membrane layer of a mixture of a perylene diimide derivative and [6, 6]-phenyl-C61 methyl butyrate, which serves as a second layer; and a [6, 6]-phenyl-C61 methyl butyrate membrane layer serving as a third layer, wherein the thickness of the perylene diimide derivative membrane layer is in the range of 10 to 30 nanos; the thickness of the membrane layer of the mixture of the perylene diimide derivative and the [6, 6]-phenyl-C61 methyl butyrate is in the range of 25 to 45 nanos; the molar ratio of the perylene diimide derivative to the [6, 6]-phenyl-C61 methyl butyrate is in the range of 4:1 to 11.6:1; and the thickness of the [6, 6]-phenyl-C61 methyl butyrate membrane layer is in the range of 3 to 15 nanos. The photocatalyst can be excited in a visible light region to decompose water into hydrogen and oxygen with the assistance from an electric field. The organic semiconductor visible light photocatalyst with the membrane structure can be used for producing hydrogen which is clean energy.

The invention relates to a composition with a muscle gain function, which comprises the following active ingredients of creatine, taurine, beetroot extract and beta-hydroxyl-beta-methyl butyrate. The invention further provides a sports drink comprising the composition, and the sports drink comprises the composition and a food additive. The sports drink has the functions that the muscle blood stream can be increased, the oxygen utilization rate can be enhanced, the sports energy consumption can be reduced, so that the motion function can be improved.

The invention relates to a method for preparing a rosuvastatin intermediate which is (R)-3-hydroxy-monomethyl glutarate and hydroxyl-protected (R)-3-hydroxy- monomethyl glutarate. According to the method, (R)-4-cyano-3-hydroxy-methyl butyrate which servers as a substrate is subjected to reaction under the action of an enzyme to generate the (R)-3-hydroxy- monomethyl glutarate, and particularly the enzyme is the recombinant nitrilase, and the reaction is carried out in a aqueous-phase buffering solution with the pH value of 7.0-9.0 at the temperature of 25-35 DEG C. Because the specific recombinant nitrilase is adopted by the method, the problems of ultralow concentration of the substrate and low conversion rate in the existing method for preparing the rosuvastatin intermediate through biological catalysis are solved. The method has the characteristics of mild reaction conditions and high reaction efficiency, is easy and convenient to operate and has important industrial application value.

The invention discloses biodiesel fuel and a preparation method thereof. The biodiesel fuel is prepared by using biomass derivative furfural and acetylpropionic acid as raw materials and by the technology of condensation, oxidation, esterification and complex formulation. The biodiesel fuel contains components of 6-furfurylidene levulinate, methyl furoate and methyl levulinate or ethyl levulinate with carbon atom number between 11 and 18. The advantages comprise that: the biodiesel fuel has high cetane number and oxidation stability, and its thermal efficiency is raised 30-40% than that of tradition biodiesel fuel. The biodiesel fuel can 100% directly be used, and can also be mixed with petroleum diesel fuel for using.

The invention provides a preparation method of a cross-linked fullerene bulk heterojunction perovskite solar cell. The method comprises the following preparation steps: dissolving methyl ammonium iodide, lead chloride and [6,6]-phenyl-C61-butyric styryl dendron ester into dimethyl formamide to prepare 30wt% of perovskite dimethyl formamide solution; processing a PEDOT:PSS solution on a substrate to form cured anode modifying layer; processing the perovskite dimethyl formamide solution on the anode modifying layer to obtain a uniformly cured bulk heterojunction photosensitive layer; processing [6,6]-phenyl-C61-methyl butyrate on the bulk heterojunction photosensitive layer to obtain a uniform electron transport layer; and processing a cathode electrode on the electron transport layer, so as to obtain the cross-linked fullerene bulk heterojunction perovskite solar cell. The perovskite solar cell prepared by the method has the advantages of high energy conversion efficiency and good photovoltaic characteristic.

The invention provides nutritive formula powder suitable for increasing muscles of old people and a preparation method of the nutritive formula powder. The nutritive formula powder comprises the efficacy components of nonfat dry milk powder, protein powder, calcium beta-hydroxy-beta-methyl-butyrate, sunflower oil powder, glucose syrup powder, fine white granulated sugar / cane sugar, fructo-oligosaccharide, galactooligosaccharide, a grape seed extract, a cucumber seed extract, a vitamin premix, a trace element premix, and a mineral premix. The nutritive formula powder is obtained in a mixing manner, particularly the calcium beta-hydroxy-beta-methyl-butyrate is added, and the components are in synergism, so that nutrient requirements of the old people can be met, concentration of amino acidsnecessary for blood is increased, the synthesis of muscle protein is stimulated, the net synthesis level of the protein of the old people is increased, the nutrient requirements of crowds with sarcopenia are met, and the nutritive formula powder can treat or prevent sarcopenia.

The invention belongs to the technical field of solar cells. a methylamine lead iodine perovskite solar cell containing an organic light emitting small molecule interface modifying layer. The methylamine lead iodine perovskite solar cell comprises from bottom to top in order: an anode of a glass substrate deposited with a uniform indium tin oxide ITO layer, a poly(3,4-ethylenedioxythiophene)-polystyrene sulfonic acid PEDOT:PSS film taken as a hole transport layer and deposited on the indium tin oxide ITO layer, an active layer, an organic light-emitting small molecule material tetraphenyl benzene diindene perylene DBP layer taken as an active layer interface modification layer and spinned on the active layer, a [6, 6]-phenylC60-methyl butyrate PC61BM layer taken as an electron transfer layer and spinned on the DBP layer, a [4,7]-diphenyl-[1,10]-phenanthroline Bphen as a cathode modification layer and deposited on the electron transfer layer, and an aluminum film or a silver film as a cathode and performing vacuum heat evaporation on the electron transfer layer.

The invention discloses a novel method for preparing and purifying 4-[9-(6-amino purine group)]-2 (S)-hydroxyl methyl butyrate. The method comprises: based on cheap and easily obtained L-malic acid, through functional group protection of one carboxyl and two carboxyls at the same time, an intermediate compound I is obtained; the intermediate compound I is selectively reduced into an intermediate ethanol II; the hydroxyl in the intermediate ethanol II is converted into an easily removed group, so as to obtain an intermediate compound III; the intermediate compound III is subjected to nucleophilic substitution reaction to obtain an intermediate compound IV; and the intermediate compound IV is subjected to protective group removal and methyl esterification simultaneously under the action of acid or alkali in the methanol to obtain a crude product of the 4-[9-(6- amino purine group)]-2 (S)-hydroxyl methyl butyrate, and a pure product is obtained after the crude product is recrystallized and purified. Compared with the prior preparation method, the method has the characteristics of low cost, mild conditions, difficult racemization of a chiral center during reaction, high production efficiency and the like, improves the quality and yield of products greatly, lowers the cost greatly, and is suitable for large-scale preparation.

The invention discloses a preparation method of an intermediate of a rosuvastatin calcium side chain, which comprises the following steps: firstly allowing (R)-4-cyano-3- methyl hydroxybutyrate to react with tert-butyl-dimethylchlorosilane, performing nitrile group hydrolysis in water phase under the action of an enzyme with the obtained (R)-4-cyano-3-tert-butyl dimethylsiloxyl methyl butyrate (II) as a substrate to generate a target product with a structure (I). The invention has the characteristics of being mild in reaction, high in yield, environment friendly, low in cost, and high in chiral purity of the prepared product.

The invention discloses a production method of S-2-aminobutanamide, pertaining to the technical field of chemical synthesis. The production method comprises the steps of: adopting L-(+)-methionine as raw material, conducting demethylthiolation hydroxylation in the presence of alcoholic solvent or ether solvent through the action of organic carboxylate containing chlorine, forming S-2-amino-4-hydroxy butyrate hydrochloride, conducting hydroxy bromination to obtain S-2-amino-4-bromobutyric acid hydrobromide, conducting methyl esterification of carboxyl to obtain S-2-amino-4-bromo-methyl butyrate hydrochloride, conducting catalysis of nickel, hydrogenation and dehalogenation to convert the S-2-amino-4-bromo-methyl butyrate hydrochloride into S-2-amino methyl butyrate, and finally conducting ammonolysis to generate the S-2-aminobutanamide. The production method of S-2-aminobutanamide has the advantages of high yield and good safety.