26 results about "Methyl butyrate" patented technology

The application relates to a method for continuously preparing imidacloprid intermediate 3-methyl-2-(4-morpholinyl)cyclobutyl acid methyl ester, and the specific steps are as follows: raw material morpholinyl propylene and methyl acrylate are respectively introduced into a preheater, then the preheated raw materials are pumped into a micro-channel reactor for reaction, after the reaction is completed, the materials are discharged from the micro-channel reactor outlet into a reaction kettle, reaction is carried out, then the cyclization liquid obtained in the reaction kettle is subjected to light removal in a light removal tower, 3-methyl-2-(4-morpholinyl)cyclobutyl acid methyl ester after light removal is collected from the tower kettle of the light removal tower, the 3-methyl-2-(4-morpholinyl)cyclobutyl acid methyl ester is introduced into a pentyl ester synthesis process, and the recovered methyl acrylate collected from the top of the light removal tower is reused in the reaction kettle to participate in the ripening reaction. The application has the advantages of high product purity, low raw material unit consumption, good safety, low labor cost and the like.

The invention relates to the technical field of flavors and fragrances, in particular to an ester compound with grass sweet fragrance, a preparation method of the ester compound and a grass sweet fragrance base. The ester compound with the grass sweet fragrance has the following structural formula: the ester compound with the grass sweet fragrance prepared by the invention is 4-(5-bromo-1H-indene-3-yl) methyl butyrate, and the compound has special aromatic fragrance and violet fragrance, and is elegant in fragrance and long in fragrance retention time. The preparation method of the compound is simple in process, convenient to operate and control, high in production efficiency and suitable for industrial production. Compared with the flower and plant sweet fragrance base without the compound, the flower and plant sweet fragrance base prepared by the invention is added with the ester compound with the grass sweet fragrance, so that the flower and plant sweet fragrance base has more prominent grass sweet fragrance, special grass fragrance accompanied by fresh and sweet fragrance and stronger violet flower fragrance note, and the fragrance quality of the base is obviously improved.

The invention relates to a mycobacterium hydrolase and application thereof in preparation of flavors and fragrances, and belongs to the fields of enzyme engineering and mining and application of new enzyme resources. The hydrolase comes from mycobacteria, and the amino acid sequence of the hydrolase is shown as SEQ ID No: 2; the hydrolase MdHDL disclosed by the invention has relatively high catalytic activity and substrate concentration tolerance, and can efficiently utilize benzyl alcohol or phenethyl alcohol to react with p-nitrophenyl methyl acetate pNPA, p-nitrophenyl methyl butyrate pNPB or p-nitrophenyl methyl caprylate pNPO to synthesize essence and perfume substances with different flavors; the method is suitable for preparing flower fragrance and fruit fragrance type flavors and fragrances such as jasmine flower fragrance, rose fragrance, pineapple fragrance, banana fragrance and apricot fragrance by an enzyme method, has obvious industrial production potential, and provides technical basis and method guidance for preparing the flower fragrance and fruit fragrance type flavors and fragrances by the enzyme method.

The invention discloses a fluorescent probe for recognizing lithium ions and a preparation method and application thereof.The method comprises the steps that rhodamine B, HATU and methyl 3-amino-3-methyl-1-butyrate are mixed and subjected to a first-step reaction, a first reactant is obtained, the first reactant, ethyl alcohol and sodium hydroxide are mixed and subjected to a second-step reaction, a second reactant is obtained and subjected to a third-step reaction, and the fluorescent probe for recognizing the lithium ions is obtained. And mixing the second reactant, crown ether, EDCI and HOBT, and carrying out a third-step reaction to obtain the fluorescent probe. According to the method, lithium ions in a complex environment can be efficiently recognized, and raw material waste and resource loss in the production process are avoided.

The invention belongs to the technical field of lubricating oil, and particularly relates to a reinforcing agent composition for improving the friction performance of No.8 hydraulic transmission oil and application. The reinforcing agent composition is prepared from the following raw materials: ethyl pyrimiphos, 2-amino-2-oxy-1-(3-phenoxy phenyl) ethyl] 2-(4-dodecylbenzene)-3-methyl butyrate, a dispersing agent and base oil A. The invention further discloses a preparation method of the reinforcing agent composition. According to the invention, a compound system of ethylpyrimidinphosphorus and 2-amino-2-oxy-1-(3-phenoxy phenyl) ethyl] 2-(4-dodecyl-phenyl)-3-methylbutyrate is adopted, so that the friction performance is excellent, the friction performance of the hydraulic transmission oil 8 # can be improved, the test requirements of an Allison C-4 paper-based friction bench are met, and the friction performance of the hydraulic transmission oil 8 # is improved. And the device can adapt to different hydraulic transmission oil formula systems.

The invention discloses a preparation method of 4-amino-6-tert-butyl-3-sulfydryl-1, 2, 4-triazine-5 (4H)-ketone and a preparation method of the 4-amino-6-tert-butyl-3-sulfydryl-1, 2, 4-triazine-5 (4H) The preparation method comprises the following steps: dissolving 3, 3-dimethyl-2-oxobutyric acid methyl ester in a solvent, adjusting the pH value to be acidic, then adding thiocarbazide and DMAP (Dimethylamino Phosphate), carrying out a heating reaction, and after the reaction is finished, carrying out filtering, solid separation, washing and vacuum drying in sequence to prepare 4-amino-6-tert-butyl-3-sulfydryl-1, 2, 4-triazine-5 (4H)-ketone. The extraction solvents used in all the steps are the same, the reaction solvent is mainly water and can be removed through anhydrous sodium sulfate, and when the reaction solvent is alcohol, the alcohol can be removed through rotary evaporation. Therefore, the discharge amount of three wastes in the reaction is small, the potential safety hazard is small, and the product yield and purity are high; raw material cost is low, and industrial production is facilitated.

The present invention relates to a synergistic composition comprising Astaxanthin, Calcium Hydroxy Methyl Butyrate (CaHMB) and Leucine with pharmaceutically acceptable additives and excipients for the promotion of muscle health. The present invention also provides a process for the preparation of the said synergistic composition. The invention provides an effective and synergistic composition to counteract sarcopenia, enhancing muscle strength, mobility, and quality of life in affected individuals.

The invention discloses a drinkable composite composition for deeply nourishing facial tissues and a preparation method of the drinkable composite composition, and relates to the field of drinks, in particular to a collagen peptide drink. 30 mL of the beverage contains the following components in parts by mass: 2.5 to 6 g of collagen peptide, 6.9 to 10.4 g of collagen tripeptide liquid, 0.001 to 0.5 g of glycosaminoglycan, 3 to 5 g of composite concentrated fruit juice, 0.1 to 1 g of calcium beta-hydroxy-beta-methyl butyrate (CaHMB), 0.003 to 0.03 g of an antioxidant and 0.01 to 0.05 g of an acidity regulator. According to the collagen peptide composite beverage provided by the invention, the functional collagen peptide and the collagen tripeptide are added, and the functional peptide has a relatively good supplement effect on corium layer collagen, so that the collagen peptide composite beverage has a good improvement effect on skin elasticity; glycosaminoglycan has a good effect on moisture absorption of a corium layer, so that the moisture content of skin is increased, and by adding calcium beta-hydroxy-beta-methylbutyrate (CaHMB), the effect of promoting synthesis of muscles is achieved, so that the muscle mass of the face is increased, and the compactness of the face is maintained.

The application discloses a local high-concentration lithium metal battery electrolyte and a preparation method and application thereof. The electrolyte comprises a lithium salt, an organic solvent, an additive and a diluent; the organic solvent comprises at least one of methyl formate, methyl acetate, methyl propionate, methyl butyrate, ethyl propionate, ethyl acetate, ethyl butyrate, methyl trifluoroacetate and ethyl trifluoroacetate; the additive comprises at least one of fluoroethylene carbonate, lithium difluorobisoxalate phosphate and lithium difluorophosphate; and the diluent is a fluorine-containing ether compound. The local high-concentration electrolyte has the advantages of high-voltage resistance of high-concentration electrolyte and inhibition of corrosion of sulfonimide-based electrolyte on aluminum foil, meanwhile, the problems of high viscosity, low conductivity and poor impregnation with a separator of high-concentration electrolyte are overcome, the cycle performance and low-temperature performance of the lithium metal battery are significantly improved, and the local high-concentration electrolyte is particularly suitable for application in a low-temperature high-voltage lithium battery. The preparation method is simple, the cost is low, and the method is suitable for industrial production.

The invention relates to cigarette flavor with passion fruit flavor, adsorption particles and application of the cigarette flavor and the adsorption particles in cigarettes. The cigarette flavor is prepared from passion fruit peel essential oil, hexyl hexanoate, benzaldehyde, methyl farnesyl butyrate, geranyl acetone, nerolidol and beta-sweet bisabolol. Six specific spice components are combined to form a mixed spice, compared with single passion fruit peel essential oil serving as a spice, the components in the spice are matched with one another and have a synergistic effect, the passion fruit flavor can be provided during cigarette smoking, the fruit aroma characteristic of cigarettes is obviously improved, the aroma coordination is good, and the flavor of the cigarettes is greatly improved. The smoke characteristic of the cigarette can be improved; and after the spice is used for slow release treatment, the stability of the flavor of the passion fruit can be maintained, and the flavor of the spice cannot be changed due to the change of the original proportion of the components in the slow release process, so that the stability of sensory expression is realized, and the sensory quality of the tobacco product is comprehensively improved.

The invention discloses a method and a process device for preparing acetic acid through catalysis of methyl acetate, and in a reaction system containing a catalyst, the methyl acetate is contacted and reacted with carbon monoxide and water to prepare the acetic acid; the catalyst contains an active element M, and M is Rh and / or Ir. According to the method, methyl acetate reacts with carbon monoxide and water under metal catalysis under the action of an Rh or Ir catalyst to be converted into acetic acid and corresponding acid. Different from a traditional concentrated sulfuric acid or benzenesulfonic acid resin catalyzed methyl acetate hydrolysis catalytic reaction process, the invention creatively provides a method for converting methyl acetate into acetic acid in a high-activity and high-selectivity manner through reaction of metal catalyzed methyl acetate with carbon monoxide and water under the action of an Rh or Ir catalyst; the catalytic activity is more than 10 times that of concentrated sulfuric acid or benzenesulfonic acid resin for catalyzing the hydrolysis reaction of methyl acetate to prepare acetic acid, and the method can also be applied to other methyl ester compounds, such as methyl formate, methyl propionate, methyl butyrate and methyl benzoate.

The invention discloses durian essence and a preparation method thereof, and the durian essence is prepared from the following raw materials: 2.0 to 3.8 percent of methyl 2-methylbutyrate, 1.6 to 3.4 percent of ethyl 2-methylbutyrate, 0.8 to 1.6 percent of 3-mercaptohexyl acetate, 0.4 to 1.2 percent of dipropyl disulfide, 0.01 to 0.1 percent of 4-mercapto-4-methyl-2-pentanone, 0.8 to 2.0 percent of citral, 1.5 to 3.0 percent of hops tincture, 1.0 to 2.2 percent of 2, 6-dimethyl-5-heptenal and 80.0 to 88.0 percent of solvent. According to the durian essence, a certain amount of acetic acid 3-mercaptohexyl ester and citral are added into common durian essence components such as methyl 2-methylbutyrate and dipropyl disulfide, and on the basis that the storage stability of the durian essence is guaranteed, the pure and full aroma profile of durian can be highly restored.

The invention relates to the field of food, in particular to calcium beta-hydroxy-beta-methyl butyrate nutrition protein powder and a preparation method thereof, and the calcium beta-hydroxy-beta-methyl butyrate nutrition protein powder is prepared from the following components in parts by mass: 6-7 parts of microcapsules, 10-12 parts of flavor protein particles, 0.5-0.7 part of a composite anti-caking flavor agent, 65-75 parts of whey protein isolate, 10-12 parts of resistant dextrin and 0.6-0.7 part of food-grade zeolite. According to the invention, through multi-structure design and process innovation, core functional components are processed by adopting a composite embedding technology, taste experience is optimized by applying a flavor anchoring technology, and uniformity and stability of the product are ensured by utilizing a stepped mixing technology. The method effectively solves the industrial common problems that functional components are poor in taste, prone to caking, uneven in mixing and the like, efficient utilization of nutritional components is achieved, the taste is remarkably improved, the product stability is comprehensively optimized, and the good market popularization value and application prospects are achieved.

The present invention relates to compounds of Formula (I) or an agronomically acceptable stereoisomers and / or salt of said compounds wherein Q, X, Y, Z, R1, R5, R6 and n are as defined herein. The invention further relates to herbicidal compositions which comprise a compound of Formula (I) and to the use of compounds of Formula (I) for controlling weeds, in particular in crops of useful plants.

The invention provides a high-transparency sulfone polymer as well as a preparation method and application thereof, the sulfone polymer comprises ester impurities with the mass percent of m, m is more than 0 and less than 0.05%, and m is more than 0 and less than 0.05%. The ester impurities are selected from one or more of methyl acetate, methyl formate, methyl N-methylbutyrate, methyl N-ethylbutyrate, ethyl acetate, ethyl formate, ethyl N-methylbutyrate and ethyl N-ethylbutyrate. The sulfone polymer provided by the invention has higher transparency.

The application relates to the technical field of edible essence. The application discloses a yogurt essence and a preparation method thereof. The raw material composition of the yogurt essence comprises ethyl maltol, vanillin, butanedione, acetic acid, ethyl acetate, propionic acid, 2,3-pentanedione, 3-hydroxy-2-butanone, butyric acid, ethyl butyrate, isoamyl acetate, methyl thio butyrate, hexanoic acid, ethyl hexanoate, 10% furanone, isoamyl butyrate, ethyl levulinate, linalool, p-cymene, 4-terpinenol, nerol, citral, geraniol, neryl acetate, geranyl acetate, D-limonene, lemon oil, distilled white lemon oil, sweet orange oil, glycerol triacetate, rosemary extract and bitter gourd extract. The yogurt essence prepared by the application has a flavor closer to real yogurt, good thermal stability and good flavor persistence.

The application discloses a preparation method of indobufen, and belongs to the technical field of drug synthesis process, wherein the preparation method is as follows: dissolving ortho-carboxyl benzamide in an organic solvent, cooling to 2-8 DEG C, adding a reducing agent, and carrying out incubation reaction, post-treatment, and obtaining compound I; mixing the organic solvent, a catalyst and the compound I, carrying out reflux water separation reaction, post-treatment, and obtaining compound II; dissolving the compound II in an organic solvent, adding an alkaline reagent, heating to 40-50 DEG C, dropwise adding 2-(4-bromophenyl) butyric acid methyl ester, then carrying out reflux reaction, post-treatment, and obtaining compound III; dissolving the compound III in an organic solvent, adjusting the pH to 10.5-11.5, stirring and reacting at 40-50 DEG C, post-treatment, and obtaining indobufen. The preparation method improves the safety of preparation, and also improves the quality and yield of the product indobufen.

The invention relates to the technical field of hydraulic transmission oil, in particular to a lubricant, a preparation method of the lubricant and application of the lubricant in hydraulic transmission oil. The lubricant comprises the following components: 6-fluoro-7-piperazine-1-methyl-4-oxo-[1, 3] thiazacyclo [3, 2-a] quinoline-3-carboxylic acid ethyl ester, alpha-cyano-3-phenoxybenzyl (R, S)-2-(4-chlorphenyl)-3-methyl butyrate, N, N-dimethylformamide, mono-succinimide and class I base oil, and is characterized in that the lubricant is prepared from the following components: 1-methyl-4-oxo-[1, 3] thiazacyclo [3, 2-a] quinoline-3-carboxylic acid ethyl ester, alpha-cyano-3-phenoxybenzyl (R, S)-2-(4-chlorphenyl)-3-methyl butyrate, 2- The liquid mixture can be stably dissolved in hydrodynamic transmission oil, the problem of compatibility between 6-fluoro-7-piperazine-1-methyl-4-oxo-[1, 3] sulfur nitrogen heterocyclic [3, 2-a] quinoline-3-carboxylic acid ethyl ester and 8 # hydrodynamic transmission oil is effectively solved, the liquid mixture accounting for 1-2% of the total weight is added into the 8 # hydrodynamic transmission oil, and the compatibility between 6-fluoro-7-piperazine-1-methyl-4-oxo-[1, 3] sulfur nitrogen heterocyclic [3, 2-a] quinoline-3-carboxylic acid ethyl ester and 8 # hydrodynamic transmission oil is improved. The friction performance of the 8 # hydraulic transmission oil can be improved, ingredients are saved, and the process method is simple.

The invention relates to pyrazolopyrimidine-5-amine compounds as well as a preparation method and application thereof, and belongs to the technical field of compounds and medicines. The preparation method comprises the following steps: protecting 5 # amino of pyrazolo [1, 5-a] pyrimidine-5-amine by adopting butyric acid methyl ester amide with large steric hindrance, enabling an electrophilic reagent (such as a halogenating agent) to highly selectively attack a 7 # site with small steric hindrance by utilizing a space shielding effect so as to obtain a key 7 # halogenated intermediate, and modifying the 5 # amino by virtue of a hydrolysis reaction, so that the pyrazolo [1, 5-a] pyrimidine-5-amine is obtained. According to the pyrazolo [1, 5-a] pyrimidine compound, the 5 # site and the 7 # site of the pyrazolo [1, 5-a] pyrimidine are accurately substituted, the 5 # site amino substituted pyrazolo [1, 5-a] pyrimidine compound is obtained, and the compound has better anti-tumor activity, provides a new drug choice for tumor treatment and enriches an anti-tumor drug library.

The application discloses a high-voltage wide-temperature electrolyte suitable for ternary lithium metal batteries, and particularly relates to the technical field of lithium metal battery electrolytes. The technical problems of the traditional electrolyte, such as easy solidification at low temperature, ion transmission obstruction, severe side reaction at high temperature and high voltage, short cycle life and insufficient wide-temperature compatibility, are solved. The electrolyte is constructed by a composite solvent system of methyl butyrate, methyl heptafluorobutyrate and fluorinated ethylene carbonate, and a composite lithium salt composed of LiBF4, LiDFOB, LiPF6 and LiFSI, and a film-forming additive of 1,3,6-hexanetricarbonitrile and vinyl sulfite, so as to form a local high-concentration electrolyte system and a positive and negative electrode double-interface stabilization protection mechanism. The electrolyte is suitable for 4.7V high-voltage ternary cathodes, has excellent rate performance and cycle stability in a wide temperature range of-40 DEG C to 45 DEG C, has good flame-retardant safety, is compatible with the existing industrial production line in the preparation process, and has outstanding industrialization landing value.

The invention belongs to the technical field of sweet potato processing, and particularly relates to a method for preventing roast sweet potatoes from spoilage, which comprises the following steps: cleaning harvested sweet potatoes, and soaking the cleaned sweet potatoes in a preservative solution for 30-60 minutes; the formula of each liter of the preservative solution is as follows: 2 g to 5 g of calcium beta-hydroxy-beta-methyl butyrate, 0.01 g to 0.03 g of potassium sorbate, 1 g to 2 g of L-methionine and water as a solvent; draining water after soaking, baking until the sweet potatoes are cooked, cooling to room temperature, spraying preservative liquid on the surfaces of the baked sweet potatoes, and drying to obtain the baked sweet potatoes; the spoilage is caused by reproduction of microorganisms, and the microorganisms comprise bacteria and / or fungi; the bacteria are at least one of staphylococcus aureus, bacillus subtilis, pseudomonas, Erwinia and lactic acid bacteria; the fungi are at least one of penicillium, aspergillus and mucor. The method provided by the invention can avoid the generation of microbial drug resistance, and can prevent the roast sweet potatoes from spoilage for a long time.

This invention belongs to the field of chemical intermediate preparation technology, and particularly relates to a method for recovering N-hydroxymethyl phthalimide from the residue of a key intermediate of 4-AA. The method includes the following steps: (1) Distillation: The toluene mother liquor produced from the preparation of methyl 2-(N-phthaliminomethyl)-3-oxobutyrate, a key intermediate of 4-AA, is filtered and distilled to obtain toluene solvent and concentrated residue. The toluene solvent is recovered and reused. (2) Hydrolysis: A hydrolysis reagent is added to the concentrated residue, with a weight ratio of concentrated residue to hydrolysis reagent of 1:(1.1-4). The mixture is heated to 30-100℃ and kept at this temperature for 1-10 hours with stirring to obtain a hydrolysis product. (3) Recovery: The hydrolysis product is cooled, crystallized, filtered, and washed with water to obtain N-hydroxymethyl phthalimide. This invention can recover effective components from hazardous waste, thereby reducing the discharge of hazardous waste and lowering the cost of hazardous waste treatment.

The present invention relates to a composition containing methyl methacrylate. The present invention provides a molded body having excellent heat resistance. A composition containing methyl methacrylate, methyl isobutyrate, and methyl acrylate, wherein the content of methyl methacrylate is 99.5 mass% or more, the concentration of methyl isobutyrate is 20 mass ppm to 300 mass ppm, and the concentration of methyl acrylate is 5 mass ppm to 200 mass ppm.

The utility model relates to the technical field of experimental apparatus, in particular to a kind of 2-bromoisobutyric acid methyl ester preparation condensation reflux device, and it is completed to the condensation reflux processing of 2-bromoisobutyric acid methyl ester by condensing device, detachable support is provided to condensing device by supporting device, support and condensing device fixed connection, reduce the situation that condensing device itself appears during operation Process shaking, through sealing device, the cleaning of equipment is facilitated, the practicability of device is improved;Including condensing device, supporting device and sealing device, supporting device is installed on condensing device, sealing device is installed on condensing device.

The application belongs to the technical field of medicine synthesis, and particularly relates to a preparation method of Mupiravir. The method adopts a one-pot method to prepare an intermediate of Mupiravir ((3AR, 4R, 6R, 6AR)-6-(4-(hydroxyamino)-2-oxymethyl)-2,2-dimethyltetrahydrofuran[3,4-D][1,3]dioxol-4-yl) isobutyric acid methyl ester (compound 1), and then Mupiravir is obtained. The method has the advantages of simple operation, simplified reaction post-processing steps, reduced use of solvent types, low raw material cost and production cost, small amount of mother liquor, green and environment-friendly production, and is more suitable for industrial large-scale production. The liquid phase purity of the obtained Mupiravir reaches more than 99.9%, and the yield reaches 78.9%.

The application discloses a lemon essence, a preparation method and application thereof, and belongs to the field of essence preparation. The lemon essence comprises the following raw materials: lemon fruit fragrance 10-15%, green fragrance 1-2%, sweet agent 1-3%, enhancer 5-10%, stabilizer 1-3%, and the rest is an alcohol solvent. The lemon fruit fragrance comprises lemon oil, sweet orange oil and D-limonene; the green fragrance comprises orange flower alcohol, leaf alcohol, linalool, oxidized linalool, alpha-terpineol, beta-terpinene, isopinocamphone and lemon aldehyde; the sweet agent comprises ethyl maltol and vanillin propylene glycol acetal; the enhancer comprises ethyl butyrate, ethyl 2-methyl butyrate, ethyl acetoacetate, leaf alcohol acetate, linalyl acetate and geranyl acetate; and the stabilizer comprises a low-carboxylic acid, a heat-resistant agent and an antioxidant. The application can inhibit the oxidation and thermal decomposition of the easily-oxidized components from the molecular level by synergistically compounding the components, significantly improves the aroma stability of the essence under long-term storage and high-temperature processing conditions, and can be widely applied in the fields of beverages, foods and the like.