1 results about "N-Butyrate" patented technology

The present application relates to the technical fields of serum creatinine detection and nanozyme preparation, and particularly relates to a double-ligand regulated Fe-MOF nanozyme and a preparation method and application thereof. The method comprises the following steps: FeCl3.6H2O, 1,10-phenanthroline and monocarboxylic acid ligand are dissolved in DMF to form solution A by stirring; terephthalic acid is dissolved in DMF to form solution B; solution B is added to solution A, ultrasonic dispersion is performed, and then the solution is transferred to a stainless steel high-pressure reaction kettle for high-temperature reaction; after the reaction is completed and cooled to room temperature, centrifugal washing and vacuum drying are performed to obtain a double-ligand regulated Fe-MOF nanozyme sample. As a ligand, n-butyric acid enhances the affinity to the substrate molecule; as a ligand, 1,10-phenanthroline increases the enzyme activity; the synergy of 1,10-phenanthroline and n-butyric acid achieves high sensitivity and specificity.