10 results about "N-Butyrate" patented technology

The present invention relates to the field of photocatalytic alcohol oxidation, and more particularly to a TiO2 / NaBr photocatalytic system for selectively oxidizing primary alcohols to produce acids under mild conditions. The present invention utilizes TiO2 as a primary catalyst and a halide salt as a co-catalyst. In an organic solvent, a primary alcohol raw material is added, and the system is developed in situ under oxygen and blue LED visible light. This photocatalytic system can efficiently complex with primary alcohol compounds. At room temperature, under the pressure of an oxygen balloon, and using ethyl acetate as the reaction solvent, it can oxidize the hydroxyl groups in aromatic and aliphatic primary alcohols to the corresponding acids. This method offers the advantages of good product selectivity, high conversion efficiency, and mild conditions. Furthermore, the catalyst is easily recyclable and the production cost is low. This method is a successful example of the photocatalytic oxidation of the biomass alcohol platform compound n-butanol to n-butyric acid.

The invention belongs to the technical field of chemical materials, and particularly relates to a preparation process of 2, 2, 4-trimethyl-1, 3-pentanediol di-n-butyrate, which comprises the following steps: by adopting a specific acid catalyst, controlling the molar ratio of 2, 2, 4-trimethyl-1, 3-pentanediol to n-butyric acid to be (1: 2)-(1: 2.5), reacting at 120-170 DEG C for 5-10 hours, filtering, washing and drying to obtain 2, 2, 4-trimethyl-1, 3-pentanediol di-n-butyrate. The method comprises the steps of reaction in a reaction kettle, separation in a first rectifying tower, neutralization and extraction in an alkaline tower, refining in a second rectifying tower and the like. The process has the advantages of small catalyst dosage, strong selectivity, reusability, unique rectification and neutralization flow combination, reaction condition optimization, mild alkali liquor neutralization and effective waste treatment. According to the technology, the product purity reaches 98-99.5%, the conversion rate is 90-95%, and the technology has the advantages of being low in cost, environmentally friendly, efficient and the like and is suitable for large-scale production.

The utility model discloses a novel catalyst reaction system for di-n-butyrate, which comprises a reaction kettle, the top of the reaction kettle is communicated with a feed pipe, the top end of the feed pipe is communicated with a barrel, the top of the barrel is communicated with a discharge pipe, a rotating rod rotationally connected with the barrel is inserted into the barrel in a penetrating manner, and the discharge pipe is communicated with the discharge pipe. A motor is fixedly connected to the bottom of the barrel, an output shaft of the motor is fixedly connected with a rotating rod, the upper half portion of the rotating rod is arranged in the air, and a baffle is arranged on the inner wall of the barrel. The device for pretreating the reactants is directly arranged at the top of the reaction kettle, the reactants can directly enter the reaction kettle after being treated, the time and the cost for transporting the pretreated reactants are effectively reduced, the practicability of the device is improved, the pretreatment effect is good, the efficiency is high, and the practicability is high. The processing efficiency of the di-n-butyrate is effectively improved.

The invention relates to a novel lithium butyrate proline eutectic salt and a preparation method and application thereof, and belongs to the technical field of medicines. According to the invention, the lithium salt of n-butyric acid and L-proline are co-crystallized for the first time, and a new molecular structure with better stability and stronger drug effect is provided. The novel lithium butyrate proline eutectic salt disclosed by the invention can be used for remarkably inhibiting the activity of GSK3beta in cell and animal models and effectively reducing the total tau protein and the phosphorylation level of the total tau protein, so that the potential value for treating neurodegenerative diseases such as Alzheimer's disease is shown; particularly, the compound has a wide application prospect in the aspects of reducing neuroinflammation and improving the neuroprotection effect. Meanwhile, the compound also has prevention and treatment values in GSK3beta-related diseases such as cancers, mental diseases and diabetes mellitus.

The application discloses a polyfructose butyrate as well as preparation and application thereof, and is prepared by combining n-butyric acid or vinyl butyrate with polyfructose to form an ester bond by using an enzymatic synthesis method. The polyfructose butyrate can be well degraded and utilized by intestinal flora, and butyric acid is simultaneously generated, so that the polyfructose butyrate not only can promote richness and diversity of intestinal flora, improve intestinal flora, but also can promote growth of probiotics and inhibit growth of harmful bacteria. The polyfructose butyrate can significantly improve intestinal inflammation of mice and relieve symptoms of intestinal inflammation. The polyfructose butyrate can make polyfructose and butyric acid exert bioactivity at specific positions in the intestinal tract, and does not cause other burdens on the body.

The application discloses a method for separating n-butyric acid in an aqueous solution by using eucalyptol and application thereof. According to the technical scheme, the eucalyptol is used as an extractant to extract the n-butyric acid in the aqueous solution, the n-butyric acid can be separated and extracted under relatively mild conditions, the separation efficiency is improved while the purity of the n-butyric acid is maintained, and the energy loss of the separation operation is reduced. The treated water body is high in safety, the residual amount of the eucalyptol and the n-butyric acid in the water is extremely low, and the wastewater can be discharged and recycled in a standard way.

Provided is a beer-taste beverage comprising 1000 ppb by mass or less of 4-vinylguaiacol, having an ethyl n-butyrate content of 140 ppb by mass or more, and comprising at least one lactone selected from γ-decanolactone and γ-undecalactone, wherein a ratio of the content (unit: ppb by mass) of ethyl n-butyrate to the total content (unit: ppb by mass) of the lactone [ethyl n-butyrate / lactone] is 1100 or less.

The present application relates to the technical fields of serum creatinine detection and nanozyme preparation, and particularly relates to a double-ligand regulated Fe-MOF nanozyme and a preparation method and application thereof. The method comprises the following steps: FeCl3.6H2O, 1,10-phenanthroline and monocarboxylic acid ligand are dissolved in DMF to form solution A by stirring; terephthalic acid is dissolved in DMF to form solution B; solution B is added to solution A, ultrasonic dispersion is performed, and then the solution is transferred to a stainless steel high-pressure reaction kettle for high-temperature reaction; after the reaction is completed and cooled to room temperature, centrifugal washing and vacuum drying are performed to obtain a double-ligand regulated Fe-MOF nanozyme sample. As a ligand, n-butyric acid enhances the affinity to the substrate molecule; as a ligand, 1,10-phenanthroline increases the enzyme activity; the synergy of 1,10-phenanthroline and n-butyric acid achieves high sensitivity and specificity.

The present invention aims to provide a butyric acid bacterium that can be safely used as an active ingredient in intestinal regulators, etc. The present invention relates to Clostridium butyricum that produces n-butyric acid and has all of the following characteristics (1) to (3): (1) Inability to utilize D-xylose (2) Inability to utilize D-trehalose (3) Compared to the Clostridium butyricum type strain NBRC13949T, the amount of formic acid produced in the culture medium after anaerobic incubation at 37°C for 72 hours was lower.

The application discloses a refrigeration oil composition and a preparation method and application thereof. The refrigeration oil composition of the application adopts a polyol ester base oil of pentaerythritol and di-pentaerythritol and short-chain acid structures of normal butyric acid, 2-ethylhexanoic acid and aliphatic carboxylic acid with a carbon atom number of 5-7, and a base oil of two components of a polyalkoxy ether base oil. By changing the proportion (or polymerization degree) and ratio of the two components, the two-phase separation temperature of the refrigeration oil composition and R290 refrigerant can be controlled, so that the application requirement of significantly improving the compatibility with R290 refrigerant is achieved. Meanwhile, the composition has good hydrolysis stability.