3 results about "N-Butyrate" patented technology

The invention relates to a novel lithium butyrate proline eutectic salt and a preparation method and application thereof, and belongs to the technical field of medicines. According to the invention, the lithium salt of n-butyric acid and L-proline are co-crystallized for the first time, and a new molecular structure with better stability and stronger drug effect is provided. The novel lithium butyrate proline eutectic salt disclosed by the invention can be used for remarkably inhibiting the activity of GSK3beta in cell and animal models and effectively reducing the total tau protein and the phosphorylation level of the total tau protein, so that the potential value for treating neurodegenerative diseases such as Alzheimer's disease is shown; particularly, the compound has a wide application prospect in the aspects of reducing neuroinflammation and improving the neuroprotection effect. Meanwhile, the compound also has prevention and treatment values in GSK3beta-related diseases such as cancers, mental diseases and diabetes mellitus.

Provided is a beer-taste beverage comprising 1000 ppb by mass or less of 4-vinylguaiacol, having an ethyl n-butyrate content of 140 ppb by mass or more, and comprising at least one lactone selected from γ-decanolactone and γ-undecalactone, wherein a ratio of the content (unit: ppb by mass) of ethyl n-butyrate to the total content (unit: ppb by mass) of the lactone [ethyl n-butyrate / lactone] is 1100 or less.

The present application relates to the technical fields of serum creatinine detection and nanozyme preparation, and particularly relates to a double-ligand regulated Fe-MOF nanozyme and a preparation method and application thereof. The method comprises the following steps: FeCl3.6H2O, 1,10-phenanthroline and monocarboxylic acid ligand are dissolved in DMF to form solution A by stirring; terephthalic acid is dissolved in DMF to form solution B; solution B is added to solution A, ultrasonic dispersion is performed, and then the solution is transferred to a stainless steel high-pressure reaction kettle for high-temperature reaction; after the reaction is completed and cooled to room temperature, centrifugal washing and vacuum drying are performed to obtain a double-ligand regulated Fe-MOF nanozyme sample. As a ligand, n-butyric acid enhances the affinity to the substrate molecule; as a ligand, 1,10-phenanthroline increases the enzyme activity; the synergy of 1,10-phenanthroline and n-butyric acid achieves high sensitivity and specificity.