189 results about "Anti-Adhesion Agent" patented technology

This invention relates to a method of inhibiting tumor cell adhesion, pain, and inflammation at a wound during a surgical procedure by delivering an irrigation solution containing a tumor cell anti-adhesion agent and a plurality of additional agents to an operative site during the surgical procedure. In addition, methods of inhibiting tumor cell attachment and implantation during a surgical procedure as well as inhibiting tumor metastasis during a surgical procedure are also provided.

Coated medical devices and methods for coating such devices are disclosed. The invention is directed to the use of an anti-adhesion agent in a coating for a medical device. More particularly, the invention is directed to a medical device comprising an anti-adhesion agent that prevents the self-adhesion of different portions of a coating disposed on the surface of the medical device. Additionally, this invention is directed to methods for coating such a medical device.

The invention relates to a paint mist coagulant. The paint mist coagulant has good anti-adhesion and coagulation effects on water-soluble and fat-soluble paints and is particularly applied to circulating water treatment of a wet paint mist removing system. The paint mist coagulant comprises an anti-adhesion agent A, a flotation agent B and a regulator C which are used simultaneously, wherein the anti-adhesion agent A is formed by combining water-soluble quaternary ammonium cationic polymer, amphoteric metal salt or polymer of the amphoteric metal salt, and a surfactant, has high electrical neutralization property, can quickly neutralize paint particle charges, and coats paint particles to make the viscosity of the paint particles lost; the flotation agent B is anionic polymer with the molecular weight of 8,000,000 to 25,000,000, has a strong coagulation effect, and can aggregate the paint particles of which the viscosity is lost; and the regulator C is used for regulating the pH of circulating water, controls the pH value of the circulating water to be between 7 and 10 commonly, and has small using amount. The paint mist coagulant is low in price, the process is stable, the total sewage discharge amount is small, and continuous production can be ensured.

The present invention discloses a drug sustained and controlled release microparticle preparation for treating intestinal diseases. The preparation comprises: a pill core containing the drug, wherein the pill core contains 5-aminosalicylic acid and an assistant material; an isolation layer for providing a smooth and flat surface for the microparticle and preventing the drug from penetrating into a sustained release coating layer, wherein the penetration of the drug into the sustained release coating layer can affect the release effect, the used material of the isolation layer comprises one or a plurality of materials selected from a water-soluble polymer and an anti-adhesion agent; the sustained release coating layer for slowly releasing the drug, wherein different drug release levels can be achieved through adjusting the thickness of the sustained release coating layer, the used material of the sustained release coating layer mainly adopts a sustained-release material; an enteric-coating layer, the enteric-coating layer is provided for avoiding the early release of the drug in gastric juice, reducing stimulation of the main drug to stomach, increasing the local concentration of the drug in the lesion location, the used material of the enteric-coating layer mainly adopts a polymer enteric material. The invention further discloses a preparation method for the microparticle preparation. According to the present invention, the drug and the sustained release coating material are uniformly dispersed on the surface of the pellet, such that the problem of mixing uniformity of the assistant material and the main drug can be effectively solved.

This invention relates to antistatic biaxially oriented polypropylene (BOPP) combination, using polypropylene as material and including opening agent, smoothness agent, antistatic agent, antioxidant, processing and heat stabilizer, wherein the antistatic agent is glycerin fatty acid ester or two ester, polyethylene glycol ester, amides and / or ethyl amines, the anti-adhesion agent is a series of silicon dioxide inorganic matters or crosslinked polysiloxane particles, the opening agent is the synthesized silicon dioxide or silicates, calcium stearate, the smoothness agent is oleic acid amide, erucic acid amide and / or silicone, and the primary and secondary antioxidants are phosphite stabilizing agent and hindered amine antioxidant. The preparation method includes adding antistatic agent, etc. additives in granulation part, and adding them into PP, mixing, and melting and granulating to obtain the BOPP antistatic resin, or pre-preparing antistatic anti-adhesion smoothness masterbatch by various components. This invention keeps the original performances of BOPP with a lower volume of auxiliaries, and obtain good performances of antistatic property, anti-adhesion, and smoothness.

The invention relates to a polypropylene composition for a transparent high temperature boiling film and a preparation method thereof. The polypropylene composition is prepared from following raw materials: impact resistant co-polypropylene resin, an antioxidant, an acid absorbent, an antistatic agent, a nucleating agent, an anti-adhesion agent, and a slipping agent. The obtained polypropylene composition has the advantages of low haze, excellent transparency, good impact resistant performance, high heatproof property, and high surface glossiness, and can be made into a highly transparent filmresistant to high temperature boiling. The haze of a cast film with a thickness of 36 [mu]m is only 0.52%. At the same time, compared with those of a film prepared from common random co-polypropylene, the tensile strength, fracture / tensile strain, and tear resistant performance of prepared film are better. The prepared transparent high temperature boiling film is mainly used in the food package field.

The present invention encompasses an oral composition containing an anti-adhesion agent, preferably a cysteine protease and most preferably ficin. In another aspect, the cysteine protease is in combination with one or more ingredients, such as antibacterial agent and surfactant. The anti-adhesion agent mitigates interaction between a subject oral cavity and plaque-forming materials.

The invention relates to a preparation method for raw material used for a bag film with two different water-soluble speeds on different parts. The bag film with two different water-soluble speeds on different parts is prepared from raw materials of two types of different water-soluble speeds. Material A and material B comprise polyving alcohol (PVA), compound plasticizer, starch or starch ether, water-soluble control regulator, smooth opening agent and anti-adhesion agent; the material A and the material B enter a twin screw to be subjected to extrusion granulation after being respectively stirred and mixed at high speed; the material A and the material B respectively pass through films obtained by extrusion and blow molding of two parallel extruders to form two films with water solubility of different types; the water-soluble disintegration time of a film area film formed by the material A is less than 30 seconds; and the water-soluble disintegration time of a film area film formed by the material B is more than 300 seconds. Meanwhile, the two film area films have similar heat-sealing temperature and performance.

The invention relates to a medical anti-adhesion agent which comprises carboxymethyl chitosan and equilibrium liquid. The solvent of the equilibrium liquid is water for injection, and the solute of the equilibrium liquid comprises sodium chloride and monopotassium phosphate. The anti-adhesion agent comprises, in weight percent, 0.1%-10% of carboxymethyl chitosan, preferably 0.2%-5% of carboxymethyl chitosan, more preferably 0.5%-4.0% of carboxymethyl chitosan, 0.5%-1% of sodium chloride and 0.1%-2% of monopotassium phosphate. The invention further relates to a method for preparing the anti-adhesion agent. The anti-adhesion agent can be in the form of gel or flushing fluid, is used for preventing postoperative adhesion in general surgery department and gynecology and obstetrics, and can also be used for surgical or trauma flushing. The anti-adhesion agent is non-toxic, non-irritant, biodegradable and free of sensitization, and has fine antibacterial activity and anti-adhesion effects.

The invention discloses a method for preparing high-rigidity chlorinated polyethylene by using a hydrochloric acid phase process, which comprises the following steps: adding high-density polyethylene, dispersing agent and anti-adhesion agent in hydrochloric acid solution in a stirring state to prepare suspension; feeding in chlorine into the suspension in two stages for implementing chlorination reaction, with the reaction temperature being from 30 to 140 DEG C, the reaction time being from 3-5 hours and the feed-in amount of the chlorine being 0.5-1.2 times as large as the weight of the high-density polyethylene; afterwards, separating, washing, dehydrating and drying the chlorinated products to result in the high-rigidity chlorinated polyethylene product with 20-35wt% of the chlorine content, DSC which is not more than 5J / g, 60-80 of Shore hardness and more than 2.0MPa of 100% modulus at definite elongation. The high-rigidity chlorinated polyethylene prepared according to the method can take the place of high-price MBS to serve as an anti-impact modifier of hard PVC articles and meet the demands of materials about rigidness and toughness.

The invention discloses an anti-adhesion and slipping agent master batch and a preparation method thereof. The formula of the anti-adhesion slipping agent master batch is prepared from 75 to 85 percent of carrier resin, 5 to 10 percent of an anti-adhesion agent, 5 to 10 percent of a slipping agent and 1 to 5 percent of a dispersing agent, wherein the anti-adhesion agent is spherical silicon aluminum oxide with the particle size of 5 to 10 [mu]m; the slipping agent is one or two of erucyl amide and oleamide; the dispersing agent is polyethylene wax with the number-average molecular weight of 3,000 to 5,000. The master batch is produced according to a conventional blending double-screw granulation process. The anti-adhesion and slipping agents in the anti-adhesion and slipping agent master batch are excellent in anti-adhesion performance, so that the friction coefficient of a thin film can be effectively reduced; the thin film is high in transparency and low in fuzzy degree; furthermore, the slipping agent is difficult to separate out.

The invention discloses a matte BOPP film and a preparation method thereof and belongs to the field of biaxially oriented polypropylene matte films. A semi-matting film is of a three-layer structure and consists of a core layer, an upper surface layer and a lower surface layer, wherein the core layer is an antistatic layer. The 1000 parts of matte BOPP film includes 659-984 parts of homo polypropylene, 36-165 parts of polyethylene-polypropylene blend, 0-165 parts of high-density polyethylene, 0-150 parts of ternary copolymerization polypropylene, 0-0.3 part of anti-adhesion agent, 2.1-8.4 parts of antistatic agent, 2.4-12 parts of modified nano-silica and 0.8-21 parts of modified nano titanium dioxide. The haze degree of the matte film is reduced, the matting effect of the matte film is softer, the matte BOPP film has stable and even matting effect, and the preparation method enables a production process to be easy to operate and control and convenient to popularize.

The invention discloses a low frog degree BOPP film and production process thereof, wherein the film is of three-layer construction formed by co-extrusion and bidirectional tension of bidirectional tension level poly-acryl resin. The top layer and the bottom layer of the film are anti-adhesion layer, comprising anti-adhesion agent 1.5-2.5% by weight percentage and acrylic resin; the middle layer is a general transparent layer comprising anti-static agent 0.5-1.5% by weight percentage and acrylic resin. The anti-adhesion agent with small grain size and ray radiation is used. The film crystallinity is controlled to reduce the frog degree of the film by regulating the formulation and the process temperature. The BOPP film has features of no addition of transparent nucleater, low production cost and high product stability.

The invention belongs to the technical field of drug preparations, and relates to a Metoprolol succinate sustained release tablet and a preparation method thereof. The sustained release tablet includes a tablet film coating material and a tablet core coated with the coating, the tablet core comprises a pellet and accessories, the pellet comprises, from the inside to the outside, a blank pill core,a drug-loading coating layer, a sustained release coating layer and a protective coating layer, the drug-loading coating layer comprises Metoprolol succinate and a drug-loading pellet coating adhesive, the sustained release coating layer comprises a sustained release pellet coating layer coating material, a pore forming agent, a plasticizer and an anti adhesion agent, the protective coating layerincludes a protection pellet coating adhesive, the accessories include a filler, a disintegrating agent and a lubricating agent. The sustained layer of the release tablet is externally wrapped with the protective layer, and the problems of slow release ability reduction and unqualified content uniformity caused by excess fluidity and the like due to the damage of the sustained release layer can be solved.

The invention discloses a BOPP matting transfer film for coating transfer. The BOPP matting transfer film for coating transfer sequentially comprises an upper surface layer, an upper core layer, a lower core layer and a lower surface layer, wherein the upper surface layer is an anti-adhesive layer; the upper core layer is a polypropylene layer; both the lower core layer and the lower surface layerare transfer layers; each transfer layer comprises the following components in percent by weight: 80-88% of matting transfer masterbatch, 4.0-8.0% of an antistatic agent, 4.0-6.0% of a slipping agentand 4.0-6.0% of an anti-adhesion agent. The BOPP matting transfer film is directly prepared by a four-layer coextrusion and biaxial stretching method. The BOPP matting film for coating transfer is uniform in matting layer surface roughness, stable in matting effect and good in transfer effect, and can be applied to transfer of leather textiles.

The invention discloses a normal temperature adhesive composition, which comprises emulsion one, emulsion two, an anti-adhesion agent, a wetting agent, an antioxidant, a defoaming agent, ammonia and water, wherein the emulsion one is one of acrylosilane emulsion, pure acrylic emulsion, styrene-acrylate emulsion, vinyl acetate / acrylic emulsion and vinyl acetate-acetate copolymer emulsion; the molecular weight of the emulsion one is smaller than 100,000 and the glass state temperature thereof is between -2 and +45DEG C; the emulsion two is one of polyacrylic emulsion, SIS latex and natural latex; and the molecular weight of the emulsion two is between 300,000 and 1,000,000, and the glass state temperature thereof is between -50 and -80DEG C; and the raw materials are added one by one, and the mixture is mixed, stirred, dispersed evenly to prepare the normal temperature adhesive composition. The sealing composition finally achieves effective sealing under the condition of different sealing pressures by properly adjusting a ratio of an adhesion system to a pressure-sensitive system according to different sealing conditions.

The invention discloses a BOPP extinction film without anti-adhesion agent, wherein the extinction film is of double-layer construction, namely a transparent layer and an extinction layer, formed by co-extrusion and bidirectional tension of bidirectional tension level acrylic resin and extinction agent; the extinction agent melt mass extruded from two auxiliary extruders is extruded into a same extinction layer by a die head adapter. The transparent layer comprises 1.5-2.5% of antistatic agent; the main component of the extinction layer is extinction agent. The dispersion of the extinction agent is uniform and the extinction effect is good. No addition of anti-adhesion agent reduces the production cost. The two auxiliary extruders extrude the extinction agent into one layer to increase the extinction agent extrusion amount, therefore the production line speed and the yield is increased.

The invention relates to a thermal transfer printing conductive film for a radio-frequency identification tag antenna. The conductive film comprises a base material, a release layer which is coated on the surface of the base material, a conductive metal layer which is evaporated on the surface of the release layer and a conductive adhesive layer which is coated on the surface of the conductive metal layer, wherein the release layer is formed by solidifying coating liquid consisting of the following components in parts by weight: 8 to 16 parts of ammonium-base modified acrylic ester, 10 to 15 percent of inorganic modified acrylic ester resin, 20 to 30 parts of dipentaerythritol hexaacrylate, 1 to 3 parts of photoinitiator, 3 to 7.5 parts of gas-phase silicon dioxide, 0.6 to 2 parts of dispersing agent, 0.4 to 1.5 parts of anti-adhesion agent and 30 to 57 parts of solvent. The radio-frequency identification tag antenna produced by adopting the thermal transfer printing conductive film has the advantages of high fineness and stability in conductivity.

The invention relates to the field of medicines, especially to a proton pump inhibitor enteric coated pellet and a preparation and a preparation method thereof. The proton pump inhibitor enteric coated pellet is composed of a blank pellet core, a drug loaded layer, a protective layer, a separating layer, a waterproof layer and an enteric coating, wherein the waterproof layer is made from zein, the drug loaded layer is composed of a proton pump inhibitor, a first binder, a first stabilizing agent, a first antiadherent and a solubilizer or of the proton pump inhibitor, the first binder, the first stabilizing agent, a filler, a disintegrating agent and a first opacifier, the protective layer is composed of a second binder, a second stabilizing agent, a plasticizer, a second opacifier and an antifoaming agent, the separating layer is made of a coating material, and the enteric coating is composed of an enteric material, a plasticiser and a second antiadherent. The proton pump inhibitor enteric coated pellet and the preparation thereof in the invention have stable properties, reliable quality and high bioavailability and can avoid burst effects and moisture absorption.

The invention relates to a holographic mold-pressing contraction substrate film and a manufacturing method thereof; the substrate film has a three-layer structure of an upper layer, a middle layer, and a lower layer, has a total thickness of 13-38 microns, and is characterized in that the upper layer has a thickness of 0.5-4 microns, and is prepared by the following raw materials by weight: 85-90% of propylene copolymer, 1-3% of anti-adhesion agents, and 6-12% of smoothing agents; the middle layer has a thickness of 12-30 microns, and is prepared by the following raw materials by weight: 76-86% of propylene homopolymer, 0.5-2% of antistatic agents, and 12-28% of petroleum resin; the lower layer has a thickness of 0.5-4 microns, and is prepared by the following raw materials by weight: 95-98% of ultralow-temperature ternary propylene copolymer, and 1-6% of anti-adhesion agents; when a holographic pattern is mold-pressed on the substrate film surface, a complete pattern (with a pattern molding rate of 100%) and the sharpness can be ensured during the mold-pressing process; no whitening occurs; the haze does not increase; and certain thermal contraction capability is maintained after mold pressing.

The invention relates to an anti-adhesion paint which comprises polyether sulfone (PES), polyphenylene sulfide (PPS), anti-adhesion agent, pigment, water and solvent. Compared with the traditional waterborne PES paint, the coating formed by adopting the anti-adhesion paint has better performances such as corrosion resistance, wear resistance, hardness, adhesive force and non-viscosity. The paint can not only be singly coated to form the finished product, but also be used as any layer of the multilayer nonstick paint.

The invention relates to a composition of azithromycin taste-masking fine pellets and a preparation method thereof. The composition is composed of drug-containing fine pellets and a coating layer, wherein the drug-containing fine pellets are composed of azithromycin, a blank pellet core, a binder, and an anti-sticking agent. The drug-containing fine pellets are coated with a coating material to obtain the taste-masking fine pellets. The particle diameter of the taste-masking fine pellets is 0.08-0.20mm. The weight percentage of each component of the taste-masking fine pellets composition is as follows:

The invention relates to a method for preparing tangerine peel oil capsule, wherein it comprises capsule material, strengthener, tangerine peel oil, emulsifier, and anti-adhesive agent at 0.5-1:0.05-0.1:0.2-1.2:0.025-0.05:0.01-0.05; atomizes and dries, to obtain the capsule at 7-30 mum. And the inventive capsule can reduce volatilization and improve stability. And it solidifies tangerine peel oil, to support storage and transmission.

The invention discloses high-shrinkage biaxially-oriented nylon 6 film with hot shrinkage reaching 8-10% and a manufacture method thereof, wherein the high-shrinkage biaxially-oriented nylon 6 film comprises 78-82 parts of nylon 6, 17-21 parts of special nylon which is one, or a combination of any, of MXD6, PA612 and PA610, 0.3-0.7 part of an anti-adhesion agent which is silicon dioxide or calcium carbonate or magnesium carbonate. The biaxially-oriented nylon 6 film manufactured according to the material ratio herein through the manufacture method reaches 8-10% in hot shrinkage, and has the advantages of high tensile strength, high puncture strength and good impact strength, and the production of high-shrinkage film with hot shrinkage reaching 8-10% from nylon is achieved.

The invention discloses a BOPP film for shallow reticulated printing, wherein the film of three-layer construction formed by co-extrusion and bidirectional tension of the bidirectional tension level acrylic resin. The shallow reticulated printing layer comprises anti-adhesion agent 2-4% wt; and the anti-adhesion layer comprises anti-adhesion agent 3-5% wt; the core layer comprises anti-static agent 0.8-1.0% wt. The anti-adhesion agent is synthetic silica and the grain size of the synthetic silica in the shallow reticulated printing has two kinds, respectively 1-2 Mum and 2-4Mum, and the ratio of 1-2 Mum to 2-4 Mum is 0.5-1.5:3.5-4.5; and the grain size of the synthetic silica in the anti-adhesion layer is 3-5 Mum. The BOPP film is used for shallow reticulated printing with good pattern hierarchicy sense, accurate overprint, no generation of lumen 'botting', strong ink adhesion force, good antistatic effect.

The invention provides an epoxy resin curing covering object, which is prepared from 100 mass parts of inorganic powder, 0 to 4 mass parts of coupling agents, 0.5 to 12 mass parts of epoxy resin, 0.5 to 7 mass parts of curing agents, 0 to 10 mass parts of diluents, 0 to 60 mass parts of dispersing anti-adhesion agents and 0 to 3 mass parts of emulsifiers through covering and curing. The invention also provides a preparation method of the epoxy resin curing covering object. The epoxy resin curing covering object can be well dispersed before the curing; after the curing, agglomeration cannot be formed; the problem that inorganic powder and polymer materials are not compatible is solved; the requirements of inorganic powder material differentiation, functionalization and high performance after the covering can be more easily realized.

The invention discloses a preparation method of a hot melt adhesive film for a vehicle flexible flat cable (FFC) wire and the hot melt adhesive film. The preparation method comprises the following steps: A, preparing a primer coating agent: step A1, adding 20-40 parts by mass of medium-molecular-weight saturated polyester and 60-80 parts by mass of a butanone-toluene solvent into a reaction kettle, and carrying out dissolving by stirring, wherein the stirring speed is 500-1000 r / min; and step A2, after the mixture in the reaction kettle in the step A1 is uniformly dissolved by stirring, carrying out cooling to the room temperature, then adding 0.1-5 parts by mass of an anti-adhesion agent and 0.5-20 part by mass of a low-temperature closed isocyanate curing agent, and uniformly carrying out dispersing by stirring. The low-temperature closed isocyanate curing agent is added into the primer coating agent, so that chemical cross-linking of the primer coating agent to a polyethylene terephthalate PET polyester film and a hot melt adhesive is increased, and the adhesive force of the primer coating agent to the PET polyester film and the hot melt adhesive under a high-temperature condition and a low-temperature condition is improved. A closed type latent curing agent is adopted in the hot melt adhesive, so that the cross-linking degree and cohesion of the hot melt adhesive are increased, heat resistance and hydrolysis resistance are improved, cracking of the hot melt adhesive is avoided, and blistering and layering between the PET polyester film and the hot melt adhesive are avoided.

The present invention provides new biopolymers which mimic the properties of natural polysaccharides found in vivo. The inventive polysaccharides can be used as viscosupplements, viscoelastics, tissue space fillers, and / or anti-adhesive agents. Also provided are pharmaceutical compositions comprising the inventive polymers and methods of using them including, for example, in the treatment of arthritic and sport-injured knee joints; in reconstruction or cosmetic procedures, intervertebral disc repair, treatment of vocal cord problems, treatment of urinary incontinence, and prevention of adhesion formation following abdominal or gynecological surgery.

The invention discloses a color biaxially-oriented polypropylene (BOPP) film which comprises a layer A, a layer B and a layer C. The layer A and the layer C are surface layers, the layer B is a core layer, and the layer A comprises 92-99.0% of homopolymerization propene polymer (PP) or random PP, 0.5-5% of color concentrate and 0.5-3% of anti-adhesion agent; the layer B comprises 92-100% of homopolymerization PP, 0-5% of color concentrate and 0-3% of antistatic agent and slipping agent; the layer C comprises 92-99.0% of homopolymerization PP or random PP, 0.5-5% of color concentrate and 0.5-3% of anti-adhesion agent. The color BOPP film is produced through the steps of material mixing, melt extrusion, casting, longitudinal stretching, transverse stretching, dragging and side cutting, rolling, slitting, finished product forming and the like. Through the production process of the color BOPP film, the solvent pollution caused by film printing and pre-coating is reduced, the processing expenses and the cost are reduced, and environment-friendly effect is achieved. Simultaneously, the color of the film does not fade and is firm and more beautiful than the color of a film produced in a printing manner.

The invention relates to an antistatic coating solution for a PET film bottom layer and a preparation method and application thereof. The antistatic coating solution for the PET film bottom layer is prepared from, by mass, 7-9% of film forming matter, 2.5-3.5% of conductive type polythiophene dispersion solution PT2, 2.0-3.0% of anti-adhesion agent, 10-20% of defoaming agent, 1.0-3.0% of surface active agent, 4-5% of sweller, 0.3-0.4% of adhesive, 60-63% of desalted water and the balance other additives. The coating solution prepared through the method needs no corona assistance, a chemical coating treatment method is adopted, the high polymer antistatic agent conductive type polythipphene PT2 is successfully introduced into the bottom layer formula, on-board coating molding is achieved at a time, the problem that the resistance of the surface of the bottom layer is high is solved, the PET bottom layer surface resistance is greatly lowered, meanwhile, the chemical adhesion performance and other properties of the coating solution are not affected, the coating solution is stable in system, and the industrial continuous production requirement can be met.