Sleep deprivation device for rats/mice

Abstract

The invention relates to a sleep deprivation device for rats / mice, which comprises a working platform, wherein the working platform is provided with standard feeding cages supported by food and waterand a guide rail, the plurality of standard feeding cages are arranged at two sides of the guide rail, at least one sleep deprivation rod walks on the guide rail, one side of each standard feeding cage, close to the guide rail, is provided with an elongated groove, and the sleep deprivation rod is inserted into the elongated groove; the sleep deprivation rod is driven by a motor, and the control end of the motor is connected with an industrial control device capable of setting motion parameters of the sleep deprivation rod; the guide rail is provided with a travel switch of the sleep deprivation rod, and the travel switch is connected with the industrial control device. The device is suitable for molding a plurality of sleep deprivation types, a plurality of groups can be carried out at the same time, and the cost is low; the environment of the mouse feeding cage is simulated by the deprivation cages, the generated stress response is small, and the interference on experimental data issmall; the rod deprivation mode is milder, the mice do not need to be in an exercise state all the time, the sleep deprivation method is mild but the deprivation effect is good, and the sleep deprivation mode more accords with a human sleep deprivation mode.

Description

technical field [0001] The invention relates to a sleep deprivation device used in animal experiments. Background technique [0002] Sleep is one of the instinctive behaviors of the body and plays an important role in the development and development of brain functions. Sleep disorders can lead to disorders of brain function, resulting in decreased immunity, mental irritability, and in severe cases affecting people's work ability and work performance. Sleep disorders are also one of the common causes of many accidents and psychological problems. Sleep deprivation is one of the important models in the study of sleep disorders, and it has received more and more attention in the study of the effects of lack of sleep or insufficient sleep on the body. [0003] Sleep deprivation refers to the state in which the body loses part or all of its normal amount of sleep due to various reasons. According to the difference in the amount of missing sleep in sleep deprivation, it can be di...

AI Technical Summary

Problems solved by technology

[0004] In order to study sleep disorders and develop anti-fatigue drugs or health products, preliminary animal experiments are required. At present, the popular sleep deprivation equipment on the market is the cage method. In the experiment of this equipment, mice are prone to feel alienated and respond easily. Stress response, the angle of the food basket and the cage is defective, and sometimes the head of the mouse is stuck between the trough and the cage, resulting in death

The first is the horizontal platform method, which is not suitable for long-term sleep deprivation, and may easily cause infection and death of mice

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