31results about How to "Crystal stable" patented technology

The invention discloses a purification method and a purification device for crystallized magnesium, and relates to the field of magnesium metal smelting. The method comprises the following steps: under the protection of an inert atmosphere, firstly carrying out pressure-applying melting treatment on a magnesium material to be smelted, and then carrying out pressure-applying filtering treatment on a product obtained after the melting treatment, so as to complete the flux-free smelting process of the magnesium material. And meanwhile, the metal magnesium liquid and most of the oxide shells are separated by utilizing the liquidity difference between the liquid metal magnesium and the solid oxide shells. Compared with a conventional smelting process without pressure application, the method has the advantages that the melting rate of the crystallized magnesium can be remarkably increased, most of oxide impurities are removed, a series of pollution problems caused by flux use are solved from the source, and low-cost, high-efficiency and high-quality smelting of the crystallized magnesium is realized.

The invention relates to the technical field of saccharide purification, in particular to a high-yield and low-color-value anhydrous beta-lactose preparation method which comprises the following steps: preparing a lactose solution by taking food-grade lactose as a raw material, adding activated carbon for adsorption, then carrying out column treatment to remove nitrogen-containing inorganic salt and organic acid, and finally carrying out film evaporation concentration to separate out beta-lactose crystals. The method comprises the following steps of: adding anhydrous beta-lactose into a reaction kettle, automatically scraping off crystals, and collecting to obtain anhydrous beta-lactose, the yield of the anhydrous beta-lactose is at least 90wt%, and the color value is lower than 25. According to the method, the yield of the beta-lactose can be improved, and the produced beta-lactose is uniform in particle size, normal in color and few in impurities.

A eutectic comprising a compound of formula 1 and oxalic acid,

The present invention provides a MOR molecular sieve membrane and a preparation method thereof, wherein the preparation method of the MOR molecular sieve membrane comprises the following steps: S1, mixing an aluminum source, an alkali solution, a silicon source, a fluoride salt, an organic alcohol and water to obtain a synthetic sol; S2, coating a seed solution on the surface of a porous carrier to obtain a seed layer; S3, coating the synthetic sol on the surface of the seed layer, and performing three temperature-variable crystallizations to obtain a MOR molecular sieve membrane; in step S1, the molar ratio of SiO2, Na2O, Al2O3, ROH, NaF and H2O is 1: (0.1-0.35): (0.03-0.15): (0.2-2): (0.1-0.5): (10-100). The present invention adds an organic alcohol to improve the crystallinity and overall structural integrity of the MOR molecular sieve membrane structure.

The invention belongs to the technical field of separation and purification, and particularly relates to a separation and purification method of 3-fucosyllactose. According to the method disclosed by the invention, the 3-FL can be efficiently separated and purified through two crystallization processes by controlling the proper graining temperature, associating the graining sugar degree with the two times of seed crystal adding time and controlling the cooling crystallization rate, so that a high-quality 3-FL crystallization product is obtained. The method is simple and convenient, is more suitable for industrial production, and can be used for extracting and purifying high-quality 3-FL only through simple and conventional pretreatment steps; more widely, the method can be used for extracting high-quality 3-FL from a crude 3-fucosyllactose solution prepared by an enzyme method and a chemical synthesis method.

Provided are a crystal of a compound of formula (I), a salt thereof, a crystal of the salt thereof, and a method for preparing the crystal, and also include use of the compound and the crystal in preparing a drug for treating IRAK4-related diseases.

The invention provides a pharmaceutical preparation of a cefotaxime sodium compound and a preparation method thereof. The preparation method comprises the following steps: S1, weighing 20.0 g of sodium acetate trihydrate, putting the mixture into a reactor, adding 40.0 mL of a crystallization solvent, stirring and dissolving the mixture for 10 minutes, and obtaining a sodium acetate trihydrate solution; S2, adding cefotaxime acid to the sodium acetate trihydrate solution, and obtaining a clear and transparent reaction solution after the salt-forming reaction is complete; S3, moving the reaction solution into a crystallizer, dripping 0.5-2 mL of a 40% alkyl glycoside aqueous solution into the crystallizer, and starting stirring; S4, starting a constant temperature ice machine, and starting to drip a dissolving agent when the solution temperature in the crystallizer reaches 20-24° C., adding a seed crystal when the solution is slightly turbid, growing the crystal for 30 minutes, and continuing to drip a dissolving agent, and adding a total of 265 mL of a dissolving agent; S5, after the dissolving and crystallization is completed, vacuum filtration is performed, and drying is performed to obtain the cefotaxime sodium compound. The present invention reduces supersaturation, reduces nucleation barriers, and weakens spontaneous nucleation through the participation of 40% alkyl glycoside aqueous solution, so as to obtain a product with a large average particle size and concentrated particle size distribution.

This invention relates to the field of water pollution purification, specifically to a process for purifying and recycling industrial wastewater. The process provided by this invention induces the in-situ crystallization and precipitation of calcium and magnesium ions, primarily in the form of aragonite-type calcium carbonate, by adding a crystal form regulator to the wastewater. This replaces the traditional precipitation method using precipitants, fundamentally preventing the generation of secondary sludge. Simultaneously, a quencher regulates the type and concentration of active free radicals within the system, achieving targeted degradation of organic matter while maximizing the retention of beneficial ions in the water, ensuring the corrosion inhibition performance of the recycled water. This invention features a simple operation, requires no mechanical structural modifications, and can be directly adapted to existing industrial water treatment systems. It effectively solves the problem of simultaneously addressing hardness removal and organic matter degradation in circulating water wastewater treatment, significantly improving the purification and recycling efficiency of wastewater. The treated effluent can be directly reused in industrial circulating water systems.

The invention provides an MOR molecular sieve membrane and a preparation method thereof.The preparation method of the MOR molecular sieve membrane comprises the following steps that S1, an aluminum source, alkali liquor, a silicon source, villiaumite, organic alcohol and water are mixed, and synthetic sol is obtained; s2, coating the surface of the porous carrier with a seed crystal liquid to obtain a seed crystal layer; s3, coating the synthetic sol on the surface of a seed crystal layer, and carrying out three times of variable-temperature crystallization to obtain an MOR molecular sieve membrane; in the step S1, the molar ratio of the SiO2 to the Na2O to the Al2O3 to the ROH to the NaF to the H2O is 1 to (0.1 to 0.35) to (0.03 to 0.15) to (0.2 to 2) to (0.1 to 0.5) to (10 to 100). The organic alcohol is added, so that the crystallinity of the MOR molecular sieve membrane structure and the integrity of the whole structure are improved.

The present invention discloses a crystal form of a polypeptide compound containing cyano substitution and a preparation method thereof, specifically discloses a crystal form of a compound of formula (I) and a preparation method thereof.

The invention discloses a dapagliflozin and metformin sustained release tablet and a preparation method thereof. The sustained release tablet comprises dapagliflozin, metformin or hydrochloride thereof, a crystal form stabilizer and a sustained release material. The dapagliflozin sustained-release tablet at least can guarantee crystal form stability for 24 months, the crystal form of dapagliflozin is stable in the whole effective period, the medicine effect is consistent, and the clinical medication effect is guaranteed. The sustained-release tablet provided by the invention has the advantages of small dosage of sustained-release materials, small tablet weight and small tablet volume, and is easier for patients to take. According to the sustained release tablet, the preparation process is simplified, the production difficulty and cost are reduced, and the production efficiency is improved.

The invention discloses a method for inhibiting oxygen vacancy of an yttrium oxide coating, which comprises the following steps: doping a dispersion stabilizer into Y2O3 powder, uniformly stirring to obtain a suspension, and sanding to obtain dispersion stabilizer-doped yttrium oxide slurry; carrying out spray drying on the yttrium oxide slurry doped with the dispersion stabilizer obtained after sanding, and granulating to obtain spherical yttrium oxide powder, wherein the particle size of the spherical yttrium oxide powder is controlled to be 42 + / -3 microns; calcining spherical particle yttrium oxide powder obtained after granulation at the temperature of 1500-1600 DEG C, screening the calcined powder, and removing powder with the particle size of less than 20 microns and powder with the particle size of more than 63.5 microns to obtain dispersion stabilizer doped yttrium oxide powder with the D50 of 35 + / -3 microns; a dispersion stabilizer doped yttrium oxide powder material is sprayed on a base material by adopting a plasma spraying technology to form the yttrium oxide spraying coating. The method can effectively inhibit the yttrium oxide powder from generating oxygen vacancy in the sanding process.

The invention provides a 4D printing PLA / TPU composite material based on cold crystallization as well as a preparation method and application thereof. The composite material is prepared from the following raw materials in percentage by mass: 50 to 100 percent of polylactic acid and 0 to 50 percent of thermoplastic polyurethane. The preparation method comprises the following steps: carrying out vacuum drying treatment on polylactic acid and thermoplastic polyurethane, uniformly mixing according to a ratio, putting into a double-screw extruder, and carrying out melt blending, extrusion and molding to obtain the composite filament. The composite filament meets the material requirements of fused deposition modeling (FDM) 3D printing, and is used for preparing 3D models such as intelligent structures and orthotics. The 3D model shows excellent shape memory performance, high mechanical strength and crystallization capacity. A 3D printing technology is utilized to construct a three-dimensional model, and a cold crystallization process and a 4D printing technology are combined, so that the PLA / TPU composite material can realize transformation from a temporary shape to a second permanent shape under external stimulation, and has an intelligent response function.

The utility model relates to phosphor copper brazing filler metal production equipment technical field especially relates to a kind of phosphor copper brazing filler metal production crystallizer flow regulating structure, including machine body, machine body is opened in crystallization cavity, and the through-hole is opened in axial two ends, the top of crystallization cavity is fixedly connected with feed pipe, the top of feed pipe is fixedly connected with adjusting pipe, the inner ring surface of adjusting pipe is fixedly connected with circular column, one end of circular column towards feed pipe is opened with moving groove, slidingly connected with sliding cylinder in moving groove, the outer ring surface of sliding cylinder is opened with multiple evenly distributed filter holes, flow sensor can real-time monitoring the flow condition of phosphor copper liquid, realize stable movement under the cooperation of guide column, to accurately adjust the flow of feed pipe, filter hole on sliding cylinder can intercept metal impurities, reduce equipment cost, simultaneously, the structure realizes the automatic regulation of flow, without manual intervention, reduce the error and hysteresis brought by human operation, and then improve the production quality and efficiency of phosphor copper brazing filler metal.

The application relates to the technical field of wastewater treatment, and particularly discloses a high-efficiency recovery and biochemical carbon source method for sodium acetate in acephate wastewater. The high-efficiency recovery and biochemical carbon source method for sodium acetate in acephate wastewater comprises the following steps: solvent recovery, high-temperature hydrolysis, methanol recovery and evaporation concentration are performed on acephate wastewater to obtain a salt-containing concentrated mother liquor and condensate water A; the salt-containing concentrated mother liquor is subjected to centrifugal separation to separate out a mixed salt containing sodium sulfate and sodium phosphate, and a salt-separated mother liquor is obtained; the salt-separated mother liquor is continuously cooled and crystallized to obtain a crystal slurry containing sodium acetate crystals; the crystal slurry containing the sodium acetate crystals is subjected to centrifugal separation to obtain a sodium acetate product and a crystallization mother liquor; part of the crystallization mother liquor is returned to a sodium acetate crystallization system to adjust the solid content of the crystal slurry, and the other part is subjected to drying treatment to obtain a mixed salt and condensate water B; the condensate water A and the condensate water B are sent to a biochemical system for treatment, and treated water is obtained.

The invention relates to the technical field of graphene production equipment, and discloses a vacuum environment and adsorption system integrated cotton stalk graphene induction device which comprises a control console, a smashing mechanism, a conveying table and a vacuum system are fixed to the upper surface of the control console, and a supporting frame is fixed to the upper surface of the control console; a first electric push rod is fixed to the inner wall of the supporting frame, a rotating disc is fixedly arranged at the output end of the servo motor, the outer wall of the rotating disc rotates on the inner wall of the control table, multiple sets of sealing boxes are arranged on the upper surface of the rotating disc, and a discharging assembly is arranged on the upper surface of the control table. Cotton stalks are poured into the smashing mechanism and mixed and smashed with salt materials, at the moment, the cotton stalks are put into the sealing box to be subjected to vacuum treatment, the cotton stalks are prevented from being burnt, the sealing box is matched with the sealing assembly, and by-products can be adsorbed while vacuum treatment is conducted; and the servo motor is matched with the turntable, so that the effect of full-automatic continuous production of graphene can be achieved.

The invention discloses portland cement clinker based on marlstone and a preparation method thereof, and relates to the technical field of cement. The method comprises the following steps: crushing, grinding and drying natural marlstone, spraying and activating by using a mixed steeping liquor containing sodium hydroxide, lanthanum nitrate and cerous nitrate, and drying and roasting at low temperature to obtain modified marlstone powder; mixing the powder with calcium carbonate, quartz powder, ferric oxide, dihydrate gypsum, calcium fluoride and barium carbonate, and pressing into a green body; and finally, sequentially carrying out two-stage mineralization calcination on the green body, introducing oxygen-enriched air in a heat preservation stage, continuously calcining, and cooling to obtain the cement clinker. According to the invention, marlstone is used as a main raw material, and the obtained cement clinker has excellent sulfate corrosion resistance through dipping activation and multi-stage calcination processes.

The invention relates to the technical field of tagatose, in particular to a tagatose crystal form and a preparation process thereof, the tagatose crystal form has characteristic diffraction peaks when the diffraction angles 2 theta are 9.94 + / -0.02, 14.43 + / -0.02, 15.04 + / -0.02, 17.36 + / -0.02, 19.69 + / -0.02, 19.98 + / -0.02, 20.28 + / -0.02, 22.09 + / -0.02, 24.59 + / -0.02, 24.79 + / -0.02, 28.18 + / -0.02, 29.11 + / -0.02, 30.17 + / -0.02, 30.88 + / -0.02, 31.30 + / -0.02, 32.07 + / -0.02, 32.53 + / -0.02, 33.38 + / -0.02, 34.49

The invention relates to the technical field of metal production, and discloses an up-drawing crystallizer with an anti-oxidation device, which comprises a crystallizer socket used for being butted with an up-drawing movable position of an up-drawing crystallization copper wire blank, the crystallizer socket is positioned in a crystallization bin, and a thermal insulation outer layer is arranged at the upper end of the crystallization bin. According to the up-drawing crystallizer with the anti-oxidation device, a first graphite guide sealing sleeve and a second graphite guide sealing sleeve are arranged in holes in the upper end and the lower end of a thermal insulation inner layer, and a first shrinkage inner plate arranged in the first graphite guide sealing sleeve is used for reducing leakage of nitrogen due to excessive nitrogen; the contraction arc piece and the movable arc piece which are arranged in the second graphite guide sealing sleeve further limit the upward guiding process of the copper wire blank, nitrogen is prevented from moving and leaking along with the copper wire blank, oxidation of metal in the crystallization process is effectively prevented through the arrangement of the first graphite guide sealing sleeve and the second graphite guide sealing sleeve, generation of oxidation impurities is reduced, and the service life of the copper wire blank is prolonged. Therefore, the purity and quality of a crystallized product are improved.

The invention provides a pyridostigmine bromide crystal and a preparation method thereof, and belongs to the field of medicine preparation. The pyridostigmine bromide crystal prepared by utilizing the intermediate I is superior to a commercially available product in purity, high in yield, free of impurity detection and superior to the prior art in quality; meanwhile, the process is simple and convenient, can be completed by conventional test equipment, and is high in batch yield, low in cost, stable in crystal form of the obtained product and suitable for industrial mass production.

The invention provides an urapidil sustained-release capsule. The urapidil sustained-release capsule comprises a sustained-release pellet and a hollow gelatin capsule shell, the sustained-release pellet comprises a blank pellet core, a medicine carrying layer and a sustained-release layer, wherein an isolating layer is also arranged between the medicine carrying layer and the sustained-release layer; the medicine carrying layer comprises an urapidil raw material medicine and an adhesive, and the isolating layer is hydroxypropyl methylcellulose and / or hydroxypropyl cellulose; the sustained-release layer comprises a sustained-release material, an enteric-coated material and a pore-foaming agent. The urapidil sustained-release capsule is stable in bulk drug crystal form, the prepared product is good in stability and stable in dissolution in the accelerated test process, and the problems that the bulk drug crystal form is changed in the drug loading process of a drug carrying layer and the drug loading efficiency is low are solved, and the problem that dissolution is fast in the accelerated test stability process of the sustained-release capsule is solved. The invention further provides a preparation method of the urapidil sustained-release capsule, by adding the isolating layer and screening a proper sustained-release layer prescription, the stability of the preparation is improved, and the safety and effectiveness of the medicine are ensured.

A crystal form of a thienoimidazole compound and a preparation method thereof, and also includes the use of the crystal form in preparing drugs for treating related diseases.

The invention discloses a zinc sulfate solution salting-out deep purification cooperated scattered metal recovery method and application. Belongs to the technical field of zinc hydrometallurgy solution purification. A cooling tower of a zinc electrolysis part is specially used for deep cooling of zinc sulfate purified liquid, a salting-out agent is added to induce calcium and magnesium to be crystallized and separated out, and macromolecular net-shaped coprecipitate is formed. Meanwhile, the coprecipitate'absorbs' part of positive ions and'leaked 'purified particle residues, solid-liquid separation is easy, and the zinc sulfate solution is deeply purified. According to the invention, energy is fully utilized, conventional impurities in the zinc sulfate purified liquid are effectively reduced, and'leaked 'and'muddy' purified residues are removed. And the scattered metal thallium and indium are recovered while the zinc electrolysis power consumption is reduced. The method disclosed by the invention is simple in process technology, easy to realize industrial application and good in economic benefit.

The invention belongs to the technical field of pharmaceutical preparations, and particularly relates to a lamidetan solid preparation and a preparation method thereof. The lamidetan solid preparation is prepared from the following raw materials: lamidetan, absolute ethyl alcohol, an absorbent, a filler, an adhesive, a disintegrating agent and a lubricant, the preparation method is anhydrous granulation. According to the lamidetan solid preparation, the lamidetan is uniformly dispersed in the absolute ethyl alcohol, moisture is not introduced, meanwhile, the wettability of API is improved, the problem of raw material adhesion is solved, the absorbent in the solid preparation can preferentially lock the moisture, and the influence of the moisture on a medicine crystal form is avoided; meanwhile, the lamidetan solid preparation disclosed by the invention also has the advantages of quick response, high bioavailability, simple preparation process and the like.

The present invention relates to crystalline forms I and II of the compound 2-N-4,6-di-O-tributyryl-D-glucosamine, preparation methods and uses thereof, wherein the crystalline forms I and II obtained from the present invention have high water solubility, crystalline stability and can be better applied in pharmacy.

The invention relates to an array substrate and a preparation method thereof, a display panel and a display device, the array substrate comprises a substrate, an array layer and a conductor layer, and the substrate comprises a first substrate, a buffer layer and a second substrate which are sequentially stacked in the thickness direction of the substrate; the array layer is arranged on the side, away from the buffer layer, of the second substrate, and the array layer comprises a plurality of transistors; the conductor layer is arranged on the side, away from the array layer, of the second substrate, and the orthographic projection of the conductor layer in the thickness direction is at least partially overlapped with the orthographic projection of the transistor. The embodiment of the invention provides an array substrate and a preparation method thereof, a display panel and a display device, which can reduce the influence of a metal layer on a transistor forming process and improve the reliability of a formed transistor.

The present invention belongs to the field of separation and purification technology, and specifically relates to a method for separation and purification of 3-fucosyllactose. The present invention can achieve efficient separation and purification of 3-FL through two crystallization processes by controlling a suitable crystallization temperature, associating the crystallization sugar content with the timing of adding seed crystals twice, and the cooling crystallization rate, so as to obtain a high-quality 3-FL crystalline product. And the method is simple and convenient, more suitable for industrial production, and only simple and conventional pre-treatment steps are required to extract and purify high-quality 3-FL by the method; more widely, the method can be used to extract high-quality 3-FL from a crude 3-fucosyllactose solution prepared by enzymatic method and chemical synthesis method.

The invention relates to the technical field of crystallization production equipment, and discloses a production equipment and method of trimethylamine oxide, comprising a base box, an outer cylinder body is sealed and fixedly installed on the top of the base box, an exhaust pipe is fixedly installed on the top of the outer cylinder body, and the production equipment and method of trimethylamine oxide are provided with an inner tank component in the outer cylinder body, and an overflow tank is provided on the inner tank component, so that a high-temperature solution will boil after entering the outer cylinder body and reducing the pressure, and then the solution therein will be evaporated, and the solute can be precipitated downward along the inner cylinder body, and the outer part of the inner cylinder body and the outer cylinder body are arranged at intervals, so that the solute that has not had time to completely precipitate can flow from the overflow tank to the first discharge pipe in an overflow manner with the flow of the solution for recirculation, heating and precipitation, thereby ensuring that the trimethylamine oxide crystals precipitated at the bottom of the inner cylinder body will not be affected by the flow of the internal fluid.

The invention discloses a cyflufenamid-fluopyram composition, the preparation raw materials at least comprise an active compound, the active compound comprises cyflufenamid and fluopyram, and the weight ratio of the cyflufenamid to the fluopyram is 1: (1-5). According to the microemulsion dosage form prepared by the invention, the particle size of the microemulsion is close to nanoscale, the microemulsion can be absorbed by crops more easily, the surface tension of contact with plant leaves is small, the microemulsion is easy to spread on the surfaces of the leaves, and liquid medicine is not easy to lose; the prepared missible oil dosage form and liquid medicine have stronger adhesion, can be mixed with a fertilizer for use, have good compatibility, and do not generate the problems of layering and flocculation; the prepared soluble concentrate can form a true solution after being diluted, and is convenient to apply and good in cold and hot storage stability. The nematicide provided by the invention is a broad-spectrum bactericide, can prevent and control alternaria leaf spot, leaf spot, gray mold, powdery mildew and the like on fruits, vegetables and field crops, is an efficient, green and low-toxicity nematicide, and has unique mobility and low toxicity.

The present invention relates to the field of inorganic non-metallic materials, and specifically discloses a high-quality silicon carbide powder, a preparation method and an application thereof. The present invention uses carbon powder and silicon powder as main raw materials, and uses silicon carbide powder of a specific particle size as an additive, and sintering at high temperature to prepare a high-quality silicon carbide powder with high loose density, good crystallization quality and high yield. The growth density of carbon inclusion defects in the silicon carbide single crystal prepared using the silicon carbide powder is low and the quality is high. The method for high-quality silicon carbide powder provided by the present invention is simple, and the raw materials are easily available, which effectively solves the problem in the prior art that the silicon carbide powder required for the growth of silicon carbide single crystals is limited in size and uneven in particle size, which leads to the easy occurrence of carbon inclusion defects in silicon carbide single crystals.