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85 results about "Disodium phosphate" patented technology

Disodium phosphate (DSP), or sodium hydrogen phosphate, or sodium phosphate dibasic, is the inorganic compound with the formula Na₂HPO₄. It is one of several sodium phosphates. The salt is known in anhydrous form as well as forms with 2, 7, 8, and 12 hydrates. All are water-soluble white powders; the anhydrous salt being hygroscopic.

Carbon fiber-based solar photothermal conversion material as well as preparation method and application thereof

The invention discloses a carbon fiber-based solar photo-thermal conversion material as well as a preparation method and application thereof, relates to the technical field of solar photo-thermal conversion materials, and solves the problems of poor mechanical performance and photo-thermal conversion performance of an existing photo-thermal conversion material. The preparation method comprises the following steps: thermally mixing a polyvinyl alcohol sodium alginate mixed solution, a graphene oxide solution and a cross-linking agent aqueous solution to prepare a cross-linking precursor solution; the preparation method comprises the following steps: by taking a carbon felt as a substrate, injecting a crosslinking precursor solution into the substrate by utilizing a vacuum infusion process, infiltrating the carbon felt, performing aging crosslinking, and then performing directional freeze drying to obtain a modified carbon felt; preparing an electroplating solution by using copper sulfate, sodium potassium tartrate tetrahydrate, disodium hydrogen phosphate and formaldehyde, adjusting the pH value by using NaOH, growing copper on the surface of the modified carbon felt by using an electroplating process, and carrying out vacuum drying; and putting the modified carbon felt subjected to vacuum drying after electroplating into a tubular furnace to obtain the carbon fiber-based solar photothermal conversion material. The method has a wide application prospect in the field of seawater evaporation desalination.
Owner:CHANGCHUN UNIV OF TECH

Phase-change composite heat and energy storage material and preparation method thereof

The invention belongs to the technical field of phase change heat storage materials, and particularly relates to a phase change composite heat storage and energy storage material and a preparation method thereof. The phase-change composite heat and energy storage material comprises the following raw material components: sodium acetate trihydrate, disodium hydrogen phosphate dodecahydrate, porous silicon dioxide, nano Al2O3, expanded graphite, borax, polyacrylamide and the balance of water. The preparation method of the material comprises the following steps: S1, heating sodium acetate trihydrate to a molten state, and dipping into porous silicon dioxide; s2, adding borax, nano Al2O3, disodium hydrogen phosphate dodecahydrate, polyacrylamide and water, and stirring for dissolving; s3, adding expanded graphite, and grinding; and S4, cooling to obtain the product. The invention aims to solve the key problems of high supercooling degree, phase separation, insufficient phase change latent heat, poor comprehensive performance and the like of the existing phase change heat storage material, and a new material meeting the requirements of building heating, industrial waste heat recovery, solar heat storage and other fields on efficient heat storage and heat management is prepared.
Owner:GUANGXI COLLEGE OF WATER RESOURCES & ELECTRIC POWER

Micro-arc oxidation electrolyte and preparation method thereof, and preparation method of oxide ceramic coating on surface of magnesium-copper dissimilar metal material component

The invention relates to the technical field of surface strengthening treatment and coating preparation, in particular to a micro-arc oxidation electrolyte, a preparation method of the micro-arc oxidation electrolyte and a preparation method of an oxide ceramic coating on the surface of a magnesium-copper dissimilar metal material component. The invention provides a micro-arc oxidation electrolyte. The micro-arc oxidation electrolyte comprises a main film-forming agent, an arcing aid, a pH regulator, a corrosion inhibitor and water, the main film-forming agent comprises ammonium fluozirconate and / or potassium fluozirconate; the arcing aid comprises one or more of disodium hydrogen phosphate, sodium dihydrogen phosphate, ammonium dihydrogen phosphate and diammonium hydrogen phosphate; the corrosion inhibitor comprises one or more of hexamethylenetetramine, ammonium bifluoride and triethanolamine. The micro-arc oxidation electrolyte breaks through the problem that valve metal and non-valve metal cannot be subjected to arc discharge at the same time for micro-arc oxidation treatment in the micro-arc oxidation process.
Owner:LANZHOU INSTITUTE OF CHEMICAL PHYSICS CHINESE ACADEMY OF SCIENCES

Preparation method of anti-pollution modified polyether sulfone nanofiltration membrane

The invention discloses a preparation method of an anti-pollution modified polyethersulfone nanofiltration membrane, which comprises the following steps: step A1, preparation of a membrane casting solution and a coagulating bath: dissolving polyethersulfone, a zwitterionic block copolymer, tetrazine modified graphene quantum dots and tetrabutyl titanate in N-methyl pyrrolidone to obtain the membrane casting solution; the zwitterionic block copolymer forms a dynamic hydration layer through strong hydration to inhibit pollutant adsorption; dissolving calcium chloride and disodium hydrogen phosphate in deionized water, adding triethanolamine to adjust the pH value of the solution to 8.0-9.0, continuously stirring, and adding norbornene modified chitosan in the stirring process to obtain a coagulating bath; the invention relates to the technical field of nanofiltration membranes. According to the preparation method of the anti-pollution modified polyethersulfone nanofiltration membrane, vertical array hydroxyapatite whiskers generated by biomimetic mineralization provide a super-hydrophilic surface to reduce organic matter adhesion; the tetrazine-norbornene light-triggered dynamic cross-linked network endows the film surface with self-repairing capability, and the use damage can be repaired.
Owner:山东九章膜新材料有限公司 +1

Urapidil hydrochloride injection and preparation method thereof

The invention provides an urapidil hydrochloride injection and a preparation method thereof, and particularly relates to the field of medicines. The urapidil hydrochloride composition comprises the following components in w / v: 0.4-0.6% of urapidil hydrochloride; 9-11% of a stabilizer; 0.03 to 0.05 percent of anhydrous disodium hydrogen phosphate; 0.1-0.3% of sodium dihydrogen phosphate monohydrate, and the balance of water for injection, which is supplemented to 100%. The defects in the prior art are overcome, the cost is saved, meanwhile, the impurity level of the urapidil hydrochloride injection after sterilization is reduced, the liquid medicine temperature is reduced in the liquid preparation and filling processes, meanwhile, the inert gas is filled, the influence of metal ions in a production assembly is greatly reduced, and the production efficiency is improved. The levels of impurities C and D in the finished product after the urapidil hydrochloride injection is sterilized are reduced; the prepared urapidil hydrochloride injection is low in impurity level and high in stability, the quality of the urapidil hydrochloride injection meets the requirements of current laws and regulations, and the urapidil hydrochloride injection is superior to a reference preparation.
Owner:JIANGSU SKYRUN PHARMA CO LTD

Preparation method of structural stable porous starch

The application discloses a preparation method of structural stable porous starch, which comprises the following steps: adding a hydrophilic colloid into deionized water to prepare a solution, then adding starch, mixing uniformly to obtain a compound suspension, heating the compound suspension at a crystal starting melting temperature, then performing vacuum freeze drying, grinding and sieving to obtain melting coated starch, adding the melting coated starch into a citric acid-sodium phosphate buffer solution, mixing uniformly to obtain a starch-buffer solution suspension, adding an enzyme to perform oscillation reaction, adjusting the reaction solution to alkaline to terminate the reaction after the reaction is completed, then adjusting the reaction solution to neutral, finally performing centrifugation, washing, vacuum freeze drying, grinding and sieving to obtain the structural stable porous starch. The method has the advantages of simple process and low manufacturing cost, and the prepared porous starch has excellent adsorption, structural stability and thermal stability, and solves the problems of complex manufacturing process, long preparation time, poor structural stability of the prepared porous starch and limited pore forming effect in the prior art.
Owner:YANGZHOU UNIV

Timolol maleate eye drops and preparation method thereof

The invention relates to the technical field of pharmaceutical preparations, and particularly discloses timolol maleate eye drops and a preparation method thereof. The timolol maleate eye drops provided by the invention are prepared from timolol maleate, glycine, trehalose, disodium hydrogen phosphate and sodium dihydrogen phosphate. According to the timolol maleate eye drops, the components of the timolol maleate eye drops are reasonably designed, and glycine and trehalose are added into the timolol maleate eye drops, so that degradation of active components of the timolol maleate eye drops is also reduced while the types and the dosage of auxiliary materials are reduced, and the eye drops have the advantages that the eye drops are safe and reliable; the stability of the timolol maleate eye drops placed for a long time is obviously improved, and the medication safety of the timolol maleate eye drops is ensured.
Owner:SHIJIAZHUANG NO 4 PHARMACEUTICAL CO LTD

A method for preparing levonoseconazole disodium phosphate

PendingCN122325502APhosphoric acidHydrolysis
The application belongs to the technical field of medicine synthesis and provides a preparation method of phosphonic acid levomoxiflazine disodium, which comprises the following steps: taking levomoxiflazine as raw material, performing esterification through phosphorus oxychloride and hydrolysis to obtain a reaction solution containing phosphonic acid levomoxiflazine; slowly and uniformly adding a sodium hydroxide methanol solution, first adjusting pH to 6.3-7.6, filtering out impurities, then adjusting pH to 9.1-9.8, crystallizing and drying to obtain a crude product; and performing recrystallization through a water-ethanol-acetone mixed system, filtering and drying to obtain a high-purity product. The application solves the problems of high impurity content and low yield in the prior art by optimizing the amount of esterification reagent, the pH adjustment mode and the recrystallization system, the HPLC purity of the obtained phosphonic acid levomoxiflazine disodium is greater than or equal to 99.97%, the maximum single impurity content is less than or equal to 0.02%, the process is simple, easy to operate, stable and suitable for industrial amplification production.
Owner:SICHUAN XINDI PHARM CHEM CO LTD

Method for detecting content of hepatocyte growth factors of mesenchymal stem cells

The invention discloses a method for detecting the content of hepatocyte growth factors of mesenchymal stem cells, and belongs to the technical field of protein detection. The method comprises the steps that an MSC cell suspension with the known concentration is taken, the MSC cell suspension and a cell lysis solution are mixed according to the set volume ratio and matched with a direct lysis technology to prepare a to-be-detected sample, and the lysis solution is prepared from disodium hydrogen phosphate, TritonX-100, NP-40 and SDS with the specific content. The lysate does not influence the combination of the antigen and the antibody, so that the content of the HGF of the mesenchymal stem cells is detected by adopting ELISA (enzyme-linked immunosorbent assay) and can be used as an important biological function index for evaluating MSC (mesenchymal stem cells) immunoregulation, tissue repair and cell apoptosis inhibition. The method is simple, convenient and efficient, compared with a traditional repeated freezing and thawing sample preparation method, the sample preparation period is greatly shortened, the sample cracking efficiency is improved, and a better sample preparation method is provided for detecting the protein content of the mesenchymal stem cells.
Owner:JIANGSU TOPCEL-KH PHARMACEUTICAL CO LTD

Method for extracting polysaccharide by reutilizing tobacco leaf residues and application

The invention relates to the technical field of polysaccharide extraction, in particular to a method for extracting polysaccharide by reusing tobacco leaf residues and application. Comprising the following steps: soaking the tobacco leaf residues obtained by supercritical extraction in a water bath, adding a disodium hydrogen phosphate-citric acid buffer solution to adjust the pH value to 4.5-5.5, adding a compound enzyme preparation, heating in a water bath for enzymolysis, boiling for inactivation, cooling, extracting by adopting a flash extraction method, filtering, concentrating under reduced pressure to obtain a concentrated solution, adding 95% ethanol for alcohol precipitation, centrifuging, taking a precipitate, and drying to obtain the tobacco leaf residues. And adding water to redissolve, adding papain to perform enzymolysis, inactivating, cooling to room temperature, centrifuging to remove the precipitate, dialyzing the crude polysaccharide solution, concentrating, and freeze-drying to obtain the refined tobacco polysaccharide. According to the method, the supercritical extraction tobacco leaf residues are used as raw materials to extract the polysaccharide, so that the extraction efficiency and the extraction rate are improved, the use of an organic solvent can be avoided, and resource waste and environmental pollution are reduced.
Owner:CHINA TOBACCO HENAN IND CO LTD

Flexible phase change energy storage ointment material as well as preparation method and application thereof

The invention provides a flexible phase change energy storage ointment material as well as a preparation method and application thereof, and relates to the technical field of phase change energy storage materials, the flexible phase change energy storage ointment material comprises sodium phosphate dibasic dodecahydrate, water, a crystal structure stabilizer, a phase change form changing agent and a phase change temperature regulator; the crystal structure stabilizer comprises at least one of glycerol, sorbitol, propylene glycol and water-soluble silicone oil; the phase change form changing agent comprises at least one of sodium alginate, gelatin, xanthan gum, water glass, sodium dodecyl sulfate, calcium chloride and sodium bicarbonate. The technical problems that the phase-change temperature of the disodium hydrogen phosphate dodecahydrate is not matched with the thermal management temperature of a human body, the phase-change material is uneven in surface and poor in comfort after liquid-solid phase change, particularly solidification and hardening, and the phase-change material is poor in cycling stability and short in service life are solved, and the effects that all the materials are compounded to play a high-efficiency synergistic effect, and the service life is prolonged are achieved. The flexible phase change energy storage ointment material has the technical effect of being suitable for human body thermal management.
Owner:YUTIAN ENERGY CO LTD

Preparation method of high-purity astragalus polysaccharide raw material powder and product thereof

The invention relates to the technical field of extraction and purification of natural medicines, and discloses a preparation method of high-purity astragalus polysaccharide raw material powder, which comprises the following steps: hot water extraction: extracting astragalus root powder of 80-120 meshes for 2-3 times at 80-90 DEG C for 1.5-2.0 hours each time according to a solid-to-liquid ratio of (1: 10)-(1: 30), merging filtrates, and concentrating under reduced pressure until the volume is 1 / 3-1 / 5 of the original volume; deproteinizing and decoloring: adding neutral protease to act for 1-4 hours at the temperature of 45-55 DEG C and the pH value of 6.5-7.5, and inactivating at the temperature of 90 DEG C for 10 minutes; adding 0.5%-2.0% of cross-linked polyvinylpyrrolidone, performing contact for 10-20 minutes, and performing solid-liquid separation to obtain clear liquid; and two-phase distribution and post-treatment: adding polyethylene glycol 4000 and sodium dihydrogen phosphate / disodium hydrogen phosphate into the clear liquid. The invention aims to shorten the process, improve the yield and purity and reduce protein / polyphenol and salt / polymer residues under the condition of not using ion exchange resin.
Owner:SHANXI UNIV

Water-based conductive silver paste and preparation method and application thereof

The invention relates to the technical field of functional paste, and particularly discloses water-based conductive silver paste, which is prepared from the following components: 50 to 60 percent of silver-coated copper powder, 0.5 to 1 percent of sodium polyacrylate, 1.5 to 3 percent of sodium carboxymethyl cellulose, 0.5 to 1.5 percent of polyvinyl alcohol, 0.3 to 2.0 percent of copovidone, 0.5 to 4.0 percent of fumed silica, 0.2 to 2.0 percent of surfactant, 0.6 to 1.4 percent of cosolvent and the balance of 0.08 to 0.12 M sodium dihydrogen phosphate / disodium hydrogen phosphate buffer solution. The content of silver in the silver-coated copper powder is 25-35%; furthermore, the water-based conductive silver paste can also comprise one or more conductive filler auxiliary materials selected from carbon nanotubes and silver-plated glass beads, and the content of the conductive filler auxiliary materials is 1-4%. The water-based conductive silver paste provided by the invention has the advantages of low cost, good environmental protection property, low drying temperature, stable performance and the like, and has a very good application prospect.
Owner:BEIJING HUAYI JINGDIAN BIOTECHNOLOGY CO LTD

Foamed acid plugging removal system and preparation method thereof

The application relates to the technical field of plugging removing agents for oilfield recovery, in particular to a foamed acid plugging removing system and a preparation method thereof. The foamed acid plugging removing system comprises a foamed acid component, a foaming agent and a gas phase component, and the foamed acid component comprises, in mass ratio, oxalic acid, phosphoric acid, triethanolamine, dimethyl diallyl ammonium chloride, acetic acid, disodium phosphate and sodium nitrite in a mass ratio of (10-12):(3-5):4:2:(1.5-2.5):0.05:0.05:1. The total weight m1 of the foamed acid component and the total weight m2 of the foaming agent satisfy the relationship m1:m2=100:(1.5-2.5). The volume V1 of the gas phase component and the total volume V2 of the foamed acid component satisfy the relationship V1:V2>=40:1. The foamed acid plugging removing system can improve the plugging removing effect of an acid plugging removing agent in a heterogeneous formation, so that the plugging material dissolution rate is above 65%, the dissolution rate is above 1.20g / (m 2 ·h), the foaming multiple is above 4.0, and the stable foaming time is above 420s.
Owner:PETROCHINA CO LTD

Composite wood aerogel for lithium battery as well as preparation method and application of composite wood aerogel

The invention provides composite wood aerogel for a lithium battery as well as a preparation method and application of the composite wood aerogel. According to the composite wood aerogel, natural wood is used as a raw material, a cellulose skeleton with an anisotropic porous structure is obtained through acid-base system delignification treatment, boric acid and activated carbon nanotubes are loaded on the cellulose skeleton in an ultrasonic cavitation mode, and the wood aerogel is formed through freeze drying; then, under the vacuum condition, phosphate phase-change materials such as disodium hydrogen phosphate dodecahydrate are adsorbed into pores of the wood aerogel, and the composite wood aerogel is obtained. According to the invention, through flame-retardant modification of boric acid, heat conduction regulation and control of activated carbon nanotubes and heat absorption and release effects of the phase change material, the composite wood aerogel has good heat management capability in the operation process of the lithium battery, and realizes cooling or thermal insulation protection under the over-temperature or low-temperature working condition of the battery; the flame-retardant and heat-insulating effects are achieved when thermal runaway occurs, thermal runaway propagation is effectively inhibited, and the safety of a lithium battery system is improved.
Owner:DALIAN UNIV OF TECH

Fexofenadine Hydrochloride Dry Suspension and Its Preparation Method

The present invention discloses a fexofenadine hydrochloride dry suspension and a preparation method thereof, which relates to the technical field of pharmaceutical preparations. The fexofenadine hydrochloride dry suspension of the present invention comprises the following components in percentage by weight: fexofenadine hydrochloride 1-6%, sodium docusate 0.01-0.06%, mannitol 1-6%, disodium hydrogen phosphate anhydrous 0.05-0.10%, citric acid 0.5-0.8%, polyvinylpyrrolidone K30 0.1-0.9%, sucrose 85-93% and silicon dioxide 0.1-0.5%. The present invention is prepared by a wet granulation method, and the obtained fexofenadine hydrochloride dry suspension has good uniformity, good taste and high stability.
Owner:GUILIN HUAXIN PHARMACY CO LTD

Preparation method of weak acid spinning silver ion antibacterial non-woven fabric

The invention relates to the technical field of antibacterial non-woven fabrics, and discloses a weak acid spinning silver ion antibacterial non-woven fabric preparation method, which comprises: taking tributyl citrate, 6-chloro-2-hexanone and 3-aminopropyltrimethoxysilane as raw materials, and carrying out a nucleophilic substitution reaction and a Schiff base reaction to prepare a weak acid spinning silver ion antibacterial non-woven fabric. The triester group trimethoxy Schiff base type silane coupling agent is prepared; on the basis of a dual coordination effect, silver ions are loaded on the surfaces of graphene nanosheets by utilizing a triester-based trimethoxy Schiff base type silane coupling agent to prepare a graphene-loaded silver ion antibacterial agent; the preparation method comprises the following steps: dispersing a graphene supported silver ion antibacterial agent in a disodium hydrogen phosphate-citric acid buffer solution, compounding with a polylactic acid solution to prepare a polylactic acid / graphene supported silver ion antibacterial agent spinning solution, and preparing the weak acid spinning silver ion antibacterial non-woven fabric by adopting an electrostatic spinning process. The antibacterial non-woven fabric product shows excellent antibacterial effect and antibacterial durability, has excellent mechanical properties, and has practical application value.
Owner:BEIZI INST (CHANGZHOU) TECH DEV CO LTD

Preparation method of dealkalized lignin / cerium-doped hydroxyapatite two-dimensional nanosheet composite material and ultraviolet shielding application of dealkalized lignin / cerium-doped hydroxyapatite two-dimensional nanosheet composite material

The invention relates to the technical field of ultraviolet shielding materials, in particular to a preparation method of a dealkalized lignin / cerium-doped hydroxyapatite two-dimensional nanosheet composite material and ultraviolet shielding application of the dealkalized lignin / cerium-doped hydroxyapatite two-dimensional nanosheet composite material. The method comprises the following steps: firstly, preparing a dealkalized lignin nanosheet through ultrasonic treatment and freeze drying, then mixing cerous nitrate, calcium chloride and disodium hydrogen phosphate powder with water to prepare a solution, and then uniformly mixing the dealkalized lignin powder with the mixed solution for microwave hydrothermal reaction; the dealkalized lignin / cerium-doped hydroxyapatite two-dimensional nanosheet composite material is obtained through centrifugation and freeze drying, a band gap with good ultraviolet absorption is obtained, the dealkalized lignin / cerium-doped hydroxyapatite two-dimensional nanosheet composite material is applied to ultraviolet shielding, the good biocompatibility of hydroxyapatite is considered, and the ultraviolet shielding effect is also provided. The large flaky hydroxyapatite nanosheets are prepared by virtue of the template effect of the dealkalized lignin, so that the agglomeration of the dealkalized lignin nanosheets is effectively inhibited, and the anti-ultraviolet effect of the dealkalized lignin / cerium-doped hydroxyapatite two-dimensional composite material is synergistically improved.
Owner:JIANGSU NAO NEW MATERIAL CO LTD

TCCA rapidly dissolving effervescent tablet and preparation method thereof

This invention belongs to the field of disinfectant technology, specifically relating to a TCCA instant effervescent tablet and its preparation method. A TCCA instant effervescent tablet, by weight percentage, is prepared from the following components: 35-50% trichloroisocyanuric acid, 8-15% urea, 10-18% anhydrous citric acid, 8-14% sodium bicarbonate, 3-8% modified starch disintegrant, 2-6% disodium hydrogen phosphate, 1-4% sodium dodecyl sulfate, 0.5-2% disodium ethylenediaminetetraacetate, 1-3% hydroxypropyl methylcellulose, 0.5-1.5% magnesium stearate, with talc to bring the total to 100%. This invention addresses the problems of existing disintegrants by preparing a modified starch disintegrant through grafting and cross-linking modifications. Experimental results show that effervescent tablets using the modified starch disintegrant of this invention have a disintegration time of only 65-112s in pure water, and the increase in disintegration time in hard water is small. After accelerated testing at 54℃ / 14d, the effective chlorine reduction rate is only 2.2-5.5%, and the increase in disintegration time is small. This indicates that the grafted and cross-linked dual-modified structure has good stability and can maintain excellent disintegration performance after heat storage.
Owner:NANNING BOYUAN SHANG TECHNOLOGY CO LTD

Sodium phosphate compound as well as preparation method and application thereof

The invention provides a sodium phosphate compound. The sodium phosphate compound comprises 15-30 parts by weight of sodium dihydrogen phosphate or a monohydrate of sodium dihydrogen phosphate; 3-6 parts by weight of disodium hydrogen phosphate; 0.05 to 0.3 part by weight of licardoine hydrochloride; 0 to 0.04 part by weight of an aromatic; and 0 to 0.25 part by weight of a sweetening agent. Sodium dihydrogen phosphate or a monohydrate of sodium dihydrogen phosphate, disodium hydrogen phosphate and lidocaine hydrochloride are prepared into a compound, and the compound is administrated when being used, so that the compound has a remarkable clinical effect when being used for cleaning intestinal tracts, the satisfaction degree of medication can be improved, the enteroscopy quality can be improved, the postoperative exhaust and defecation time can be shortened, and postoperative complications can be reduced.
Owner:SICHUAN JIAN NENG PHARM CO LTD

Biological fermentation liquor with multiple efficacy, preparation method thereof and cosmetic

The application provides a biological skin activity fermentation liquor with multiple effects, a preparation method thereof and a cosmetic, and relates to the cosmetic field.The method comprises the following steps: mixing camellia oleifera seed meal, protease, cellulase, lipase and water to obtain a first mixture; performing enzymolysis on the first mixture to obtain a fermentation substrate; performing second mixing on the fermentation substrate, glucose, peptone, yeast powder, disodium hydrogen phosphate and citric acid, and sterilizing to obtain a fermentation culture medium; activating bacillus velezensis through an LB culture medium to obtain a seed liquid; performing third mixing on the seed liquid and the fermentation culture medium, and performing fermentation to obtain a camellia oleifera seed meal fermentation liquor; performing centrifugation on the camellia oleifera seed meal fermentation liquor to obtain a centrifuged fermentation liquor; performing fourth mixing on the centrifuged fermentation liquor and polysaccharide-degrading enzyme, performing enzymolysis, and performing filtration to obtain the biological skin activity fermentation liquor with multiple effects.The method not only improves the high-value utilization of the camellia oleifera seed meal, but also obtains the biological skin activity fermentation liquor with high safety and outstanding activity.
Owner:HUNAN YUJIA COSMETICS MFG CO LTD

Negative plate surface vulcanization treatment method and vulcanization treatment surface thereof

The invention discloses a cathode plate surface sulfuration treatment method and a sulfuration treatment surface thereof, and relates to the technical field of cathode plate surface treatment.The cathode plate surface sulfuration treatment method comprises the following steps that after a cathode plate is pretreated, pulse current deposition is conducted in sulfuration liquid, and after-treatment is conducted, the cathode plate can be obtained; the vulcanizing liquid comprises a sulfur source, ammonium citrate, hydroxylated carbon nanotubes, potassium perfluorohexyl sulfonate and a boric acid-disodium hydrogen phosphate buffer system; the sulfur source is at least one of thiosulfate, thiourea or sodium sulfide. The porosity of the vulcanized surface is less than or equal to 2.0%, the uniformity is less than or equal to 5%, and the vulcanized surface has good adhesive ability.
Owner:HUNAN DAZHIDU NEW MATERIAL TECH CO LTD

Fluconazole ear drops and preparation method thereof

ActiveCN121287617AOrganic active ingredientsSenses disorderCelluloseEar fungal infections
The invention discloses fluconazole ear drops and a preparation method of the fluconazole ear drops, and belongs to the technical field of ear drop preparations. The composition comprises the following components in percentage by mass: 0.6%-2.0% of fluconazole, 8%-20% of propylene glycol and / or diethylene glycol monoethyl ether, 20%-32% of glycerol or caprylic / capric polyethylene glycol glyceride, 0.1%-1% of hydroxypropyl methylcellulose, 0.05%-0.2% of anhydrous disodium hydrogen phosphate and the balance of anhydrous citric acid and water. By improving the prescription of the fluconazole ear drops, the solubility of the fluconazole is increased, the content of the fluconazole in the prepared fluconazole ear drops reaches 2%, the fluconazole ear drops are good in stability, and compared with the prior art, the fluconazole ear drops have a better treatment effect on ear fungal infection.
Owner:GUANGZHOU BOJI MEDICINE SERVICES

Preparation method of rivastigmine new-form salt compound and rivastigmine new-form salt compound preparation

The invention provides a rivastigmine new-form salt compound and a preparation method of a rivastigmine new-form salt compound preparation. The rivastigmine new-form salt compound is prepared from the following rivastigmine salt and auxiliary materials in percentage by mass: 1.5%-3% of rivastigmine salt, 5%-10% of polysorbate 20, 1%-8% of polyethylene glycol-4000, 0.15%-1.5% of citric acid, 0.5%-1.0% of anhydrous disodium hydrogen phosphate, 0.1%-0.5% of sodium hydroxide and 80%-90% of water for injection. The invention also discloses a method for preparing a preparation by using the compound. The preparation process of the preparation disclosed by the invention is simple, is suitable for large-scale production of enterprises, and has great market development prospects. The preparation disclosed by the invention adopts a new administration mode, and the characteristics of the preparation are utilized, so that the medicine is slowly dissolved out subcutaneously; therefore, the purpose of reducing side effects of intestinal tracts is achieved. The preparation disclosed by the invention is stable in blood concentration and good in tolerance.
Owner:WUXI FORTUNE PHARMA

Phase change material for building as well as preparation method and application of phase change material

ActiveCN120098613AHeat-exchange elementsHeat proofingStrontium chloride hexahydrateCellulose
The invention relates to a phase-change material for a building as well as a preparation method and application of the phase-change material. The phase-change material for the building comprises the following components in parts by weight: 600-800 parts of a cooked phase-change material, 20-30 parts of a nucleating agent and 1-5 parts of a temperature regulator, wherein the cooked phase change material is a mixture of anhydrous calcium chloride, sodium carbonate decahydrate and disodium hydrogen phosphate dodecahydrate; the nucleating agent is a mixture of strontium chloride hexahydrate, polyethylene glycol and carboxymethyl cellulose, and the temperature regulator is urea. According to the application, the phase-change material for the building is used for preparing a phase-change composite vacuum insulation panel, the material is large in phase-change latent heat and high in cycling stability, the phase-change material serves as the hydrated salt phase-change material for the building, the problem that the unit volume / mass enthalpy value of phase-change microcapsules used for traditional buildings is low is solved, and the phase-change material has the advantages of being appropriate in phase-change temperature, high in cycling stability and the like. The material is used for preparing the vacuum insulated panel, and the heat insulation effect is good.
Owner:CHINA STATE CONSTR HAILONG TECH CO LTD +2

A water-based conductive silver paste, a preparation method and application thereof

This application relates to the field of functional paste technology, specifically disclosing an aqueous conductive silver paste comprising the following components: 50-60% silver-coated copper powder, 0.5-1% sodium polyacrylate, 1.5-3% sodium carboxymethyl cellulose, 0.5-1.5% polyvinyl alcohol, 0.3-2.0% co-povidone, 0.5-4.0% fumed silica, 0.2-2.0% surfactant, 0.6-1.4% co-solvent, and the balance being 0.08-0.12M sodium dihydrogen phosphate / disodium hydrogen phosphate buffer; the silver content in the silver-coated copper powder is 25-35%; furthermore, the aqueous conductive silver paste may also contain one or more conductive filler additives, namely carbon nanotubes and silver-plated glass microspheres, at a content of 1-4%. The aqueous conductive silver paste provided by this application has advantages such as low cost, good environmental friendliness, low drying temperature, and stable performance, and has good application prospects.
Owner:BEIJING HUAYI JINGDIAN BIOTECHNOLOGY CO LTD

Chemiluminescent substrate solution as well as preparation method and application thereof

The invention discloses a chemiluminescence substrate solution as well as a preparation method and application thereof, and belongs to the technical field of magnetic particle chemiluminescence immunoassay. The chemiluminescent substrate solution takes a (4-chlorobenzene sulfydryl) (10-methyl-9, 10-dihydroacridine methylene) phosphate disodium salt derivative as a core luminescent substrate, the core luminescent substrate is matched with a 50-200mmol / L buffer matrix, a 0.01-10mg / L fluorescence enhancement substance containing aromatic groups and a 1-1000mg / L inorganic or organic background inhibitor and a surfactant, the pH value is controlled at 7.5-10, and 0.01-0.2% of a preservative can be selectively added. According to the substrate solution, the synergistic effect of all the components is utilized, and the advantages of short luminescence platform period, long luminescence duration and remarkably improved detection sensitivity and stability are achieved. The method can be widely applied to detection of biomarkers in chemiluminescence immunoassay, can improve the clinical detection speed, shorten the detection time and guarantee the result accuracy, and has good practical value and popularization prospect.
Owner:SHENZHEN TAILORED MEDICAL LTD

Recombinant human platelet-derived growth factor eye drops

The invention provides a liquid composition containing recombinant human platelet-derived growth factors. The composition comprises the following components: polyvinyl alcohol, hydroxypropyl methyl cellulose, sodium dihydrogen phosphate, disodium hydrogen phosphate, sodium chloride, mannitol and the like. The invention also provides a preparation method of the composition and application of the composition in preparation of corneal injury treatment medicines. The eye drops prepared from the composition disclosed by the invention have good stability and safety, and have a good effect in repairing corneal injury.
Owner:QINGCHENG NEW DRUG BIOTECHNOLOGY (QINGDAO) CO LTD

Liquid pharmaceutical composition of tretinoin

The present invention relates to a liquid pharmaceutical composition comprising (i) totally dissolved tretinoin or a pharmaceutically acceptable isomer thereof; (ii) d-alpha-tocopheryl polyethylene glycol 1000 succinate (TPGS); (iii) a pH-modifying agent selected in the group consisting of meglumine, potassium hydroxide (KOH), sodium hydroxide (NaOH), sodium acetate (anhydrous, trihydrate, and mixtures thereof), potassium acetate (anhydrous, trihydrate, and mixtures thereof), di-potassium hydrogenophosphate, di-sodium hydrogenophosphate, tri-sodium phosphate, tri-potassium phosphate, and mixtures thereof; and (iv) water. The present invention also relates to the medical uses of such a composition.
Owner:INSTITUT GUSTAVE ROUSSY +1

A freeze-drying method for a lyophilized product of levonikkomycin disodium phosphate for injection

The present application relates to the technical field of chemical medicine preparation, and particularly discloses a freeze-drying method of injection phosphonic acid left-onitrazole ester disodium freeze-dried product. The present application pre-freezes phosphonic acid left-onitrazole ester disodium liquid at-20℃ to-15℃, freezes the obtained suspension material at-60℃ to-40℃ to obtain frozen solid, sublimates and dries the frozen solid at-12℃ to-8℃, and analyzes and dries at 15℃ to 25℃ to obtain injection phosphonic acid left-onitrazole ester disodium freeze-dried product. In the pre-freezing stage, the phosphonic acid left-onitrazole ester disodium liquid gradually changes from liquid to suspension material with uniform solute, and the solute is not frozen solid; in the freezing stage, the suspension material is gradually frozen solid; in the sublimation drying stage, the free water in the material is removed by one-stage heating, which greatly shortens the freeze-drying time; finally, the bound water in the material is removed in the analysis stage, and the moisture and impurity content in the freeze-dried product are lower.
Owner:SHIJIAZHUANG NO 4 PHARMACEUTICAL CO LTD