66 results about "Hyperbranched polyglycerol" patented technology

The present invention concerns a process for producing hyperbranched, dendritic polyglycerol from glycerol comprising the following steps: (a) adding in a vessel glycerol and a CaO-based catalyst, (b) flushing an inert gas, preferably carbon dioxide, to the resulting mixture and hermetically closing the reaction vessel, allowing pressure to build up from 1 to 10 bar above atmospheric, preferably from 2 to 6 bar; (c) heating the reaction mixture at a reaction temperature of at least 100 DEG C and below its boiling point; (d) maintaining the reaction conditions until at least 40 wt.% of glycerol is polycondensed and converted into hyperbranched polyglycerol, with concomitant water formation,, (e) separating the dendritic polyglycerol from other components present in the mixture; such as water, catalyst and reaction by-products such as hydroxyacids and glycerol carbonate esters obtained by condensation of deprotonated glycerol and carbon dioxide as well as minor amounts of cyclic compounds. (i) characterized in that, the calcium based catalyst is nanostructured calcium oxide in the form of a powder of mean particle size smaller than 100 nm measured according to ASTM D4464

Core-shell particles and methods of making and using thereof are described herein. The core is formed of or contains one or more hydrophobic materials or more hydrophobic materials. The shell is formed of or contains hyperbranched polyglycerol (HPG). The HPG coating can be modified to adjust the properties of the particles. Unmodified HPG coatings impart stealth properties to the particles which resist non-specific protein absorption and increase circulation in the blood. The hydroxyl groups on the HPG coating can be chemically modified to form functional groups that react with functional groups and adhere the particles to tissue, cells, or extracellular materials, such as proteins.

A hyperbranched polyglycerol is employed as a process stabilization aid of pregnant liquor of a Bayer process of producing alumina from bauxite. The hyperbranched polyglycerol has a molecular weight of from about 1,000 to about 1,000,000.