9 results about "Eicosapentanoic acid" patented technology

The present invention relates to an orally administrable nutraceutical composition comprising omega- 3 fatty acids, at least one plant-derived extract exhibiting hypolipidemic activity, and an antioxidant. Hie composition is formulated as a nanoemulsion to enhance bioavailability, improve gastrointestinal absorption, and increase the therapeutic efficacy of the active compounds. The synergi stic interaction between omega- 3 fatty-7 acids and the bioactive component of plant extract promotes significant reduction in blood plasma triglyceride levels, supporting cardiovascular health. Hie formulation demonstrates improved pharmacokinetic parameters, including enhanced systemic exposure of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), compared to commercially available omega- 3 supplements, including increased bioavailability under both fasted and fed conditions. This invention offers a novel strategy for enhancing the therapeutic efficacy of omega- 3 fatty acids in the management of cardiovascular diseases.

Isotopically modified polyunsaturated lipids containing a 1, 4-diene system are provided.SOLUTION: Wherein R and R ' comprise residues of linolenic, arachidonic, eicosapentaenoic, or docosahexaenoic acids, or esters thereof, wherein the esters, if present, are C1 - C21 alkyl esters, wherein the ruthenium complex further comprises a cyclopentadiene (Cp) ligand, and wherein the ruthenium in the ruthenium complex is in the + 1 oxidation state (Ru + 1).SELECTED DRAWING: None

A method for the fractionation of fatty acids with a difference of two carbons by molecular distillation with double pass fractionation between eicosapentaenoic and docosahexaenoic acids, and compositions of microorganism oils enriched in eicosapentaenoic or docosahexaenoic acid. The method wherein (i) a reaction step between an microorganism oil including omega-3 polyunsaturated fatty acids in triglyceride form and an alcohol in the presence of a chemical or enzymatic catalyst, (ii) a first step of molecular distillation under high vacuum of the oil from step (i), in a scraper film evaporator coupled to a rectification column including at least seven theoretical plates, and recovery of a first residue and distillate, (iii) a second step of molecular distillation under high vacuum of the step (ii) residue, in the scraper film evaporator, and recovery of a second residue and distillate.

The invention relates to a rapid excavation technology for phosphatidylcholine type DHA / EPA and phosphatidyl ethanolamine type DHA / EPA based on mass spectrum dual-mode multiple characteristics, and belongs to the field of research on chemical components of aquatic products. Phospholipid-type EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid) components have wide pharmacological activity and good bioavailability, mainly exist in aquatic products such as fishes, shrimps, shellfish and algae, are important nutrient elements which are indispensable to human bodies but cannot be synthesized by themselves, have indispensable effects on human health, and can be used for preparing health-care food. Wherein phosphatidylcholine type DHA / EPA (PCEPA / DHA) and phosphatidyl ethanolamine type DHA / EPA (PEEPA / DHA) are reported at most. According to the method, the krill oil and the fish oil are analyzed by adopting a liquid chromatography-tandem high-resolution mass spectrometry technology, a plurality of mass spectrometry characteristics of positive and negative ion dual modes and python programming are fused to construct a rapid mining algorithm, PCEPA / DHA and PEEPA / DHA in the krill oil and the fish oil are discovered, and an effective technical support is provided for deep discovery, development and utilization of high-value phospholipid DHA and EPA in the krill oil and the fish oil.

This invention discloses a method for preparing fish oil, belonging to the field of deep oil processing technology. The method includes the following steps: crude fish oil is sequentially subjected to transesterification and enrichment to obtain a mixed ester with high contents of eicosapentaenoic acid ester and docosahexaenoic acid ester. Then, in a choline chloride-glycerol eutectic solvent, the mixed ester undergoes a transesterification reaction with glycerol using Lipozyme TL IM catalysis to generate and separate crude fish oil. Finally, impurities are removed to obtain fish oil. This invention completely avoids the use of organic solvents, employs mild reaction conditions, and utilizes the extremely low solubility of the products in the eutectic solvent, resulting in in-situ layering. This simplifies product separation, allows for the recycling of the eutectic solvent, and is economical, environmentally friendly, and suitable for industrial production.

The invention provides a functional fortified nutritional supplement composition for pets, a pet food and application of the pet food, and relates to the technical field of pet foods. The functional fortification nutritional supplement composition for the pets is composed of krill oil and krill meal, and the composition provides eicosapentaenoic acid and docosahexaenoic acid with the daily intake of 130-400 mg for the pets. Through the specific combination of the krill oil and the krill meal, 130-400 mg of EPA and DHA can be provided for pets every day. Experiments prove that under the condition of the efficacy threshold value, the health condition of pets can be effectively improved, especially on the basis of maintaining normal physiological indexes, the fur quality can be remarkably improved, the anti-oxidation and immunocompetence of organisms can be enhanced, the inflammatory response can be effectively adjusted, and the heart health risk index can be reduced; the intestinal barrier function and the flora steady state are improved, and the multi-dimensional and synergistic health strengthening effect is achieved.

The invention provides an enrichment method of giant salamander grease unsaturated fatty acid, a product and application, and belongs to the technical field of grease extraction. The enrichment method of the giant salamander grease unsaturated fatty acid comprises the following steps: (1) hydrolyzing refined giant salamander grease to obtain a reaction product; (2) performing multi-stage extraction on the product by adopting a composite solvent, and collecting a polyunsaturated fatty acid enrichment liquid; (3) adding a crystal nucleus inducer into the obtained polyunsaturated fatty acid enriched liquid, then carrying out continuous stage cooling from 20 DEG C to-45 DEG C, and collecting a concentrated solution rich in eicosapentaenoic acid and docosahexaenoic acid; and (4) carrying out phospholipid embedding treatment on the concentrated solution to obtain a stable unsaturated fatty acid enriched product. According to the method disclosed by the invention, all the process steps have a synergistic effect, so that the enrichment efficiency and the product purity of polyunsaturated fatty acids in the giant salamander grease, especially EPA and DHA, can be effectively improved.

The invention discloses a feed for pork enriched with omega-3 polyunsaturated fatty acids and a preparation method of the feed. The core of the feed is a strain-prebiotics-plant polyphenol synergistic interaction feed system. The feed comprises the following components in parts by weight: 1-5 parts of an intestinal adaptive functional strain preparation, 2-8 parts of an omega-3 precursor in which alpha-linolenic acid is 45%-60%, 1-4 parts of a prebiotic compound and 0.1-0.3 part of plant polyphenol. Through a closed-loop mechanism that prebiotics promote strain colonization, strains convert alpha-linolenic acid into eicosapentaenoic acid and docosahexaenoic acid, strain metabolites activate polyphenol to resist oxidation and polyphenol promotes omega-3 muscle transport, the conversion rate of alpha-linolenic acid is 38%-45%, the oxidation rate of pork omega-3 is reduced by 40%-50%, and the conversion rate of alpha-linolenic acid is reduced by 40%-50%. The proportion of eicosapentaenoic acid and docosahexaenoic acid in the muscle is 65%-75%; and the enzyme activity of the strain can be optimized through a temperature response promoter, the conversion efficiency is further improved by 15-20%, the scheme realizes multi-effect accurate regulation and control, and the application prospect is wide.

The invention relates to the technical field of chemical separation, in particular to a method for extracting eicosapentaenoic acid and docosahexaenoic acid by taking fish oil or algal oil as a raw material. The method specifically comprises the following steps: extracting a fatty acid mixture obtained by taking crude ester type fish oil or crude ester type microalgae oil as a raw material by taking a ternary dual-system compound solvent consisting of a metal ion solution and a deep eutectic solvent as an extracting agent to obtain eicosapentaenoic acid and docosahexaenoic acid; wherein the eutecticevaporate solvent is a degradable biomass-based green natural eutecticevaporate solvent, and the volume ratio of the metal ion solution to the eutecticevaporate solvent is 0.05-3. According to the method, the metal ion complexing extraction agent with the highest yield is compounded with the degradable environment-friendly green eutectic solvent to serve as the extraction agent of the EPA and the DHA, high-selectivity extraction can be conducted on the EPA and the DHA in the fish oil or the algae oil, the preparation process is safe and simple, the condition is mild, the period is short, the cost is low, the yield is high, the product purity is high, and the method is suitable for industrial production. Good industrial production application prospects are realized.