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1 results about "Lipid storage" patented technology

Application of stub1 gene, its encoding protein and functional mutant in regulating lipid metabolism and preparation of medicine for preventing or treating obesity and related metabolic diseases

PendingCN122440830ALipid storageDyslipidemia
The application discloses STUB1 application of the gene or the STUB1 protein coded by the gene in the preparation of a medicine for preventing or treating obesity and related metabolic diseases STUB1 The application first proves that the gene and the coded protein are key target points for regulating fat metabolism, and the bidirectional regulation value is determined: on one hand, inhibition of STUB1 can significantly up-regulate the CIDEC protein level, promote normal fat storage of adipocytes, and improve insulin resistance and non-alcoholic fatty liver disease; on the other hand, activation of STUB1 can accelerate the degradation of CIDEC, inhibit lipid storage, realize the effect of reducing fat, and provide a brand-new intervention target point and treatment idea for metabolic diseases such as obesity, type 2 diabetes and dyslipidemia.
Owner:TIANJIAN ADVANCED BIOMEDICAL LABORATORY