21 results about "Vitamin E Acetate" patented technology

The invention provides a multilayer lutein ester liposome as well as a preparation method and application thereof, and belongs to the field of food processing. The multi-layer lutein ester liposome is prepared from the following raw materials: 30 to 50 parts of lutein ester, 40 to 60 parts of soybean phosphatidylcholine, 5 to 20 parts of cholesterol, 10 to 25 parts of starch sodium octenylsuccinate, 20 to 40 parts of trehalose, 15 to 30 parts of mannitol, 4 to 10 parts of phosphatidyl glycerol, 1 to 2 parts of vitamin E acetate and 1 to 2 parts of ascorbyl palmitate. According to the present invention, through the specific food-grade raw material composition and the accurate ratio relationship, the comprehensive delivery system is constructed for the highly hydrophobic and unstable lutein ester, and the system synchronously achieves the high encapsulation efficiency, the excellent stability, the good water dispersibility and the slow release function.

The invention belongs to the field of polymer chemistry and biological medicine materials, and relates to application of a polymer polysaccharide slow-release carrier in medicinal and edible components and a preparation method of the polymer polysaccharide slow-release carrier. The carrier is composed of phytic acid-genipin cross-linked modified chitosan, tannic acid, sodium lactate, glycerin, vitamin E acetate, sodium alginate and deionized water. The phytic acid-genipin cross-linked modified chitosan is prepared by reacting chitosan with phytic acid and genipin, and has reversible cross-linking and polydentate coordination properties; the tannic acid and the modified chitosan can form a multi-point hydrogen bond and esterification network. The carrier is prepared through sol-gel forming or spray drying, is stable in structure, good in dispersity, high in drug loading capacity, stable in an acid environment and controllable in release under a neutral condition, remarkably improves the slow release performance and bioavailability of medicinal and edible components, and is suitable for functional food and drug delivery systems.

The invention belongs to the technical field of pet nutrition, and discloses a trace element composite additive for improving the reproductive performance of pets, which comprises the following raw materials: zinc sulfate, sodium selenite, copper sulfate, manganese sulfate, vitamin E acetate, L-lysine hydrochloride, taurine, methionine, selenium yeast and zeolite powder. The zeolite powder is subjected to a specific acid treatment activation process, so that the adsorbability and the stability are improved. The invention also discloses a preparation method of the additive. A three-step mixing process is adopted to ensure the uniformity of the product. The additive is suitable for being added into feed in the breeding period of canine or feline pets, the adding amount of the additive is 0.1-0.5% of the total weight of the feed, and the feeding time is 1 month before breeding and 1 month after breeding. Through scientific proportioning of organic trace elements and inorganic trace elements, in combination with specific amino acids and vitamins, the components have a synergistic effect, so that the pregnancy rate, the litter size and the survival rate of newborn animals of pets are remarkably increased, and meanwhile, the pet feed has good storage stability and use safety.

The application discloses a waterproof makeup composition in the field of cosmetics and a preparation method thereof. The composition comprises a self-repairing organic silicon polyurethane elastomer, double-hydrophobic modified nano silicon dioxide, cyclopentasiloxane, red iron oxide, hydroxyethyl cellulose, polyglyceryl isostearate, sodium hyaluronate, phenoxyethanol, vitamin E acetate and deionized water. The preparation process comprises the following steps: dissolving the self-repairing organic silicon polyurethane elastomer in cyclopentasiloxane to form an oil phase; dissolving hydroxyethyl cellulose in water and then adding other components to form an aqueous phase; mixing and emulsifying the two phases, adding double-hydrophobic modified nano silicon dioxide and other components for grinding, and finally adjusting the pH value. The composition has excellent waterproof performance, long-lasting makeup effect and self-repairing function, and has good skin compatibility.

Disclosed herein are compositions for topical treatment that can include a therapeutic agent (preferably a topical antimicrobial or antifungal agent such as efinaconazole, tavaborole, or ciclopirox), a non-volatile organic solvent (preferably natural or synthetic vitamin E or vitamin E acetate), and optionally an emollient (such as cholesterol). Also disclosed herein are methods of treating diseases or disorders (preferably as a disease or disorder of the nail, nail bed, or skin, such as onychomychosis) by topically administering compositions that can include a therapeutic agent, a non-volatile organic solvent, and optionally an emollient.

The present application relates to the technical field of animal breeding, and discloses a compound nutritional health supplement for laying hens in the egg production period and a preparation and application thereof, which comprises the following raw materials in mass fractions: motherwort 1200-1400 parts, radix astragali 150-250 parts, radix codonopsis 80-120 parts, betaine hydrochloride 500-700 parts, butyric acid clostridium 50-70 parts, bacillus licheniformis 90-110 parts, vitamin acetate 3-5 parts, coated 25-hydroxy-cholecalciferol 1-2 parts, vitamin E acetate 15-25 parts, and rice husk powder 0-411 parts. The formula can scientifically and comprehensively regulate the digestion and absorption of nutrients, immune function and reproductive system health of laying hens, improve the eggshell quality, egg weight and nutritional quality of egg products, has stable effect and strong universality, greatly reduces the side effects and body burden caused by long-term medication while ensuring the effect, and is more suitable for the concept of healthy breeding; the health level of the body is comprehensively improved, the intestinal flora balance is maintained by probiotics, the immunity and stress resistance of laying hens are overall enhanced, the nutrient utilization rate is improved, and healthy high yield is achieved.

The invention discloses a preparation method of vitamin E acetate, which comprises the following steps: taking 2, 3, 5-trimethylhydroquinone diester and isophytol as raw materials, and carrying out catalytic reaction in Lewis acid and a catalytic promoter to synthesize the vitamin E acetate. According to the preparation method, aqueous hydrochloric acid is avoided from being used by adding a catalyst aid, the vitamin E acetate can be prepared in one step through reaction, meanwhile, the content of key impurities A and B can be obviously reduced, and the content of product impurities A + B is low.

The application provides a preparation method of high-content vitamin E acetate. The preparation method comprises the following steps: 2,3,5-trimethylhydroquinone (II) and isophytol (III) are subjected to condensation reaction in an organic solvent under the action of hydrogen halide, a catalyst and an impurity inhibitor to obtain tocopherol (IV); the impurity inhibitor is one or a combination of more than two of pentadecylamine, hexadecylamine, heptadecylamine, octadecylamine, nonadecylamine, eicosylamine and corresponding isomers or corresponding halogen acid salts; and the tocopherol (IV) and acetic anhydride are subjected to esterification to obtain vitamin E acetate (I). The method is simple, the reaction condition is easy to realize, the catalyst consumption is small, the catalyst and the impurity inhibitor are easy to reuse, and the method is safe, green and environmentally friendly; the method effectively inhibits reaction by-products, such as impurity A and impurity B, improves reaction selectivity and conversion rate, and improves product content and yield.

The application provides a vitamin premix and a preparation process thereof, and belongs to the technical field of food additives, and the preparation process is as follows: adding mixed microparticles of fat-soluble vitamins, mixed water-soluble vitamins and mixed minerals into a mixer and mixing, then adding vitamin C, magnesium taurate, amino acids and tricalcium phosphate and continuing to mix, and sieving to obtain the vitamin premix. The raw materials of the mixed microparticles of fat-soluble vitamins include vitamin A, vitamin E acetate, vitamin D3, vitamin K2, acacia, modified protein and beta-cyclodextrin; the raw materials of the mixed water-soluble vitamins include vitamin B1, vitamin B2, vitamin B5, vitamin B12, folic acid and nicotinamide; and the raw materials of the mixed minerals include ferrous glycinate, calcium citrate, magnesium citrate and zinc glycinate. The vitamin premix prepared by the application can be used in various foods as a nutritional supplement, is convenient to use, and has good stability and mixing uniformity.

The invention discloses pranoprofen eye drops and a production process thereof. Comprising the following raw material components in parts by weight: 0.1 to 0.5 part of pranoprofen, 1 to 5 parts of vitamin E polyethylene glycol 1000 succinate, 2 to 6 parts of soybean phospholipid, 3 to 8 parts of polyoxyethylated castor oil EL-40, 0.1 to 0.3 part of histidine, 0.2 to 0.6 part of sodium dihydrogen phosphate, 0.3 to 0.7 part of disodium hydrogen phosphate, 2 to 5 parts of glycerol, 1 to 4 parts of polyethylene glycol 400, 0.05 to 0.2 part of sodium hyaluronate, 0.1 to 0.4 part of D-panthenol and 0.01 to 0.03 part of benzalkonium chloride. The injection comprises the following components in parts by weight: 0.05-0.15 part of potassium sorbate, 0.005-0.02 part of epsilon-polylysine, 0.01-0.05 part of edetate disodium, 0.02-0.08 part of vitamin E acetate, 0.005-0.015 part of L-cysteine and the balance of water for injection, and the total weight part of the water for injection is 100 parts. According to the invention, pranoprofen is taken as a core, and vitamin E polyethylene glycol 1000 succinate, soybean phospholipid and polyoxyethylated castor oil EL-40 are adopted for synergistic solubilization, so that the problem of poor water solubility of the medicine is solved; histidine and phosphate are compounded for buffering and are matched with multiple stabilizers, so that the stability of the preparation is improved.

The invention belongs to the technical field of pharmaceutical preparations, and particularly discloses an anti-schizophrenia lyotropic liquid crystal long-acting injection and a preparation method and application thereof, and the anti-schizophrenia lyotropic liquid crystal long-acting injection is composed of an anti-schizophrenia drug, an amphiphilic compound and an organic solvent; the anti-schizophrenia medicine is selected from any one of brexpiprazole, cariprazine and aripiprazole; the amphiphilic compound is selected from any one or more of soybean phosphatidylcholine, egg yolk phosphatidylcholine, glyceryl monooleate, glyceryl monopalmitate, glyceryl dioleate, glyceryl trioleate, vitamin E acetate and phytantriol; the organic solvent is selected from one or more of ethanol, N-methyl pyrrolidone, dimethyl sulfoxide and 1, 2-propylene glycol. The anti-schizophrenia lyotropic liquid crystal in-situ gel long-acting injection forms a stable semi-solid drug reservoir through solvent exchange after administration so as to play a therapeutic effect in long-acting treatment of positive schizophrenia and negative schizophrenia and prevention of schizophrenia relapse.

The invention relates to a preparation method of vitamin E acetate, which comprises the following steps: taking 2, 3, 5-trimethylhydroquinone diacetate and isophytol as basic raw materials, and reacting under the synergistic catalysis of Lewis acid and Bronsted acid to synthesize the vitamin E acetate. According to the preparation method, through proportion coordination of the two acids, namely, the two acids participate in the acid content change based on a substrate in the reaction, the synthesis targets of high reaction selectivity (greater than or equal to 98.5%), low product hydrolysis selectivity (less than or equal to 0.5%) and the like can be achieved.

The lip plumper composition described in this patent introduces a novel chemical blend of hydrating, plumping, and nourishing ingredients designed to enhance lip volume while maintaining long-term lip health. The product is formulated using a combination of Botanisil PDH-151, Botanessential Olive S-EHO, Botanol HSO, Vitamin E Nicotinate, and Benzyl Nicotinate, with additional stabilizers such as Aerosil R 974 and a flavor component. The lip and skin treatment composition described in this patent utilizes a two-phase emulsion system to deliver multi-functional cosmetic benefits, including hydration, firmness, and anti-aging effects. The formula combines an oil-based Phase 1, containing Emulsil WO 3155, Euxyl PE 9010, and Vitamin E Acetate, with a water-based Phase 2, containing Water, Propandiol, Sodium Nitrate, Caffeine, Algacktiv Collage, and Botanecuetical.

This invention discloses a bactericidal and deodorizing Polygonatum toothpaste and its manufacturing process, belonging to the field of oral care products technology. By weight, the total mass of 100 parts comprises the following raw materials: 18-22 parts hydrated silica, 25-30 parts sorbitol, 8-12 parts glycerin, 1.5-2.5 parts sodium lauroyl sarcosinate, 0.3-0.6 parts xanthan gum, 0.4-0.7 parts sodium carboxymethyl cellulose, 0.1-0.15 parts sodium saccharin, 0.1-0.2 parts sodium benzoate, 2.5-4.0 parts composite modified Polygonatum extract, 3.0-5.0 parts supported silica, 0.1-0.3 parts dipotassium glycyrrhizate, 0.05-0.15 parts vitamin E acetate, and the balance being deionized water. This invention significantly improves the antibacterial activity and bioavailability of Polygonatum through multi-stage modification technology, achieving long-term controlled release of active ingredients. The two modified components work synergistically to target 12 major odor-producing bacteria in the oral cavity. With an antibacterial rate of ≥90% within hours, fresh breath lasting ≥13 hours, improvement rate of gingival bleeding ≥83%, and enamel wear rate ≤0.01%, it is gentle and non-irritating, suitable for all types of people.

The invention relates to the technical field of biological medicine, and particularly discloses erythromycin nano-liposome as well as a preparation method and application thereof. Vitamin E acetate and resveratrol are adopted to construct a dual stable system, a high-pressure homogenization method is adopted to prepare the erythromycin nano-liposome, and the erythromycin nano-liposome has the advantages of high transdermal efficiency, excellent bioavailability, strong stability, high encapsulation efficiency, accurate targeting, medication safety and the like. On the basis, the invention further provides the erythromycin in-situ gel which is good in clinical efficacy, safe and comfortable in medication and good in stability and biocompatibility, meanwhile, the appearance smoothness after wound healing can be improved, and the dual requirements of patients for wound healing efficiency and healing quality can be better met. The invention can be applied to the field of external preparations.

Disclosed are personal care compositions, e.g., skin care compositions, comprising at least one taurate surfactant, e.g., sodium methyl palmitoyl taurate, and at least one topically active compound, e.g., vitamin E acetate, as well as to methods of using these compositions.

The invention discloses amoxicillin sodium and clavulanate potassium for injection and a preparation method of the amoxicillin sodium and clavulanate potassium, and relates to the technical field of pharmaceutical preparations. The preparation method comprises the following steps: adding vitamin E acetate and poloxamer 124 into absolute ethyl alcohol, and uniformly mixing to obtain a mixed solution A; adding amoxicillin sodium and potassium clavulanate into the mixed solution, and uniformly mixing to obtain a mixed solution B; and adding the mixed solution B into a spray dryer, and carrying out spray drying in an inert dry atmosphere to obtain the amoxicillin sodium and clavulanate potassium powder. Vitamin E acetate and poloxamer 124 are added into medicine molecules, and the inlet and outlet temperatures are controlled in cooperation with a spray drying process, so that the amoxicillin sodium and clavulanate potassium powder is obtained. The stability of amoxicillin sodium and clavulanate potassium for injection can be effectively improved.

This invention discloses a squalane lip essence oil and its preparation process, comprising the following raw material components: Phase A: tridecyl trimellitate; diisostearyl malate; ethylhexyl palmitate; 972 hydrogen powder; Phase B: glyceryl behenate / eicosadecanate; polyisobutylene; Phase C: hydrogenated (styrene / isoprene) copolymer / pentaerythritol tetra(bis-tert-butylhydroxyhydrogenated cinnamic acid) ester; plant squalane; camellia seed oil; shea butter; avocado oil; baobab oil; comfrey oil; vitamin E acetate; Phase D: pigment; The lip essence oil of this invention can significantly moisturize and nourish, and has repairing, anti-inflammatory and soothing effects on the lip skin.

The invention belongs to the technical field of cigarette harm reduction and functionalization, and particularly relates to a vitamin E lipidosome-containing composition with slow-release anti-oxidation and sensory improvement functions and a method for preparing a tobacco filter product by using the vitamin E lipidosome-containing composition. Comprising an oil-phase composition and a water-phase composition, the oil-phase composition comprises vitamin E acetate, soya bean lecithin and beta-sitosterol, the water-phase composition comprises a stabilizer, and the weight ratio of the oil-phase composition to the water-phase composition is 3: 4. The lipidosome powder is added into the filter tip through an alcohol-free formula and an emulsification technology, so that the original function of the filter tip is maintained, free radical damage in smoke flow is effectively delayed, and the smoking smoothness is improved. The process has the characteristics of simplicity and convenience in operation, environment friendliness and low toxicity, and the obtained functional filter tip is suitable for industrial production.

The invention discloses a soothing and repairing mask and a preparation method thereof, and belongs to the technical field of cosmetics. Chlorosulfonic acid and chitosan are mixed, stirred and reacted to obtain sulfonated chitosan; mixing the sulfonated chitosan, zinc sulfate and a sodium tripolyphosphate solution, stirring and reacting to obtain complexed chitosan; mixing the complexed chitosan, silk fibroin and laccase, stirring and reacting to obtain a modified chitosan complex; mixing and stirring the modified chitosan complex, the modified pullulan polysaccharide compound and sodium alginate to obtain a soothing and repairing compound; hydroxyethyl cellulose, xanthan gum, glycerin, 1, 3-propylene glycol, allantoin, disodium ethylene diamine tetraacetate, a repairing and relieving compound, a centella asiatica extract, panthenol, sodium hyaluronate, vitamin E acetate, ceramide 3B, 1, 2-hexanediol, caprylyl glycol, ethylhexylglycerin and deionized water are mixed and stirred, and mask essence is obtained; cleaning and dehydrating the mask base cloth, and soaking the mask base cloth into the mask essence to obtain the soothing and repairing mask.

This application discloses a thermo-pressure dual-trigger microcapsule and its preparation method, as well as a lipstick. The thermo-pressure dual-trigger microcapsule includes: a core material, which comprises a first core material component, a second core material component, and a third core material component; and a shell layer, which covers the outer periphery of the core material and comprises a first shell layer component and a second shell layer component; the first core material component is at least one of squalane, hydrogenated polyisobutylene, caprylic / capric triglyceride, isononyl isononanoate, jojoba oil, squalene, and meadowfoam seed oil; the second core material component is at least one of vitamin E acetate, tocopherol, vitamin E linoleate, rosemary extract, and ascorbyl palmitate; the third core material component is at least one of phytosterols, cholesterol, phytosphoin, ceramide, and bisabolol; the first shell layer component is a polymethyl methacrylate cross-linked polymer; and the softening point of the second shell layer component is 30℃-50℃.