The invention relates to the technical field of traditional Chinese medicines, and discloses a
ginseng-
salvia miltiorrhiza brain-dredging dropping
pill for treating apoplexy and a preparation method thereof, and the preparation method comprises the following steps: (1) preparing
ginseng,
salvia miltiorrhiza and
ligusticum wallichii into clear paste, and crushing to obtain paste
powder; (2) carrying out reaction on
epoxy modified
glyceryl trioleate,
poloxamer and
triethylamine in DMF (
Dimethyl Formamide), adding glyceryl monooleate, and carrying out secondary reaction; performing reduced pressure
distillation and purification to obtain a mixture; stirring and mixing the mixture, a
polymer of 2-methacryloyloxyethyl
phosphorylcholine and
polyethylene glycol to obtain a matrix; and (3) heating and mixing the paste
powder and the matrix, and dripping into a cooling agent to prepare the dropping
pill. The dropping
pill has the effects of promoting
blood circulation, tonifying qi, dispelling wind and removing obstruction in the meridians, can be used for treating
stroke diseases, has high
drug loading capacity and good appearance quality, is quick to dissolve and take effect quickly in the initial stage, is stable and slow-released in the later stage, ensures the long-term
drug effect, and remarkably improves the
bioavailability of drugs.