111 results about "Double emulsion" patented technology

The invention discloses a dual-mode micro-droplet generation micro-fluidic chip and application thereof in generation of dual-emulsion droplets, and relates to the technical field of micro-fluidic chips. The method comprises the following steps: respectively injecting two different internal phase solutions from the left ends of respective iron tubes, guiding the internal phase solutions to a wedge-shaped tube orifice of a theta-shaped glass capillary tube through respective thin tubes, injecting an intermediate phase solution into a square glass tube through an intermediate phase inlet by using a No.1 needle, and injecting an external phase solution into the square glass tube through an external phase inlet by using a No.2 needle; the two internal phase solutions, the intermediate phase solution and the external phase solution converge at an inlet of the circular glass capillary tube, and after entering the circular glass capillary tube, water-in-oil-in-water double-emulsion droplets are obtained. The invention can obtain the dual-mode micro-droplet generation micro-fluidic chip and the application of the dual-mode micro-droplet generation micro-fluidic chip in generation of dual-emulsion droplets.

The invention discloses a preparation method and application of a targeted delivery system of a metal polyphenol nano system. The invention discloses a targeted delivery system of a metal polyphenol nano system, and a preparation method of the targeted delivery system comprises the following steps: taking the metal polyphenol nano system formed based on epigallocatechin gallate and iron ions as a carrier, and loading fucoxanthin to prepare fucoxanthin nano particles with active oxygen response characteristics; then, after chondroitin sulfate capable of targeting macrophages and (5-carboxyl amyl) triphenyl phosphorus bromide capable of targeting mitochondria are coupled, the fucoxanthin delivery system with the active oxygen response characteristic and the targeting characteristic is further prepared through a double emulsion anti-solvent evaporation method. The system can realize release of fucoxanthin under stimulation of active oxygen, and realizes aggregation of a targeted delivery system in mitochondria of a specific inflammation site. The carrying system can effectively improve or relieve the inflammatory bowel disease, and the raw materials used in the carrying system are low in cost, the preparation conditions are mild, and large-scale production is easy.

The invention provides a Ziegler-Natta catalyst silicon-magnesium composite carrier and a preparation method thereof, a continuous phase silicon solution is prepared by using a double template agent, the continuous phase silicon solution is mixed with a cross-linking agent and an initiator to obtain a dispersed phase, the dispersed phase is subjected to two-phase speed regulation mixing through a micro-fluidic chip to finally obtain double emulsion droplets, and then operations such as curing, template agent removal and acid etching are performed to obtain the Ziegler-Natta catalyst silicon-magnesium composite carrier. The preparation method comprises the following steps: preparing a spherical silicon dioxide carrier with more excellent performance, then carrying out magnesium source loading and post-treatment, and finally preparing the Ziegler-Natta catalyst silicon-magnesium composite carrier with monodispersity, hierarchical porous structure (micropore-mesopore-macropore), high loading rate and high mechanical strength, and is suitable for industrial-scale polypropylene catalyst production. The prepared catalyst carrier is more perfect in morphology and more uniform in particle size.

The invention provides tranexamic acid-glutathione-containing compound emulsifiable paste and a preparation method thereof.W1 / O / W double emulsion phase structural design is adopted, reduced glutathione is encapsulated in an acidic inner water core, an oil phase is stabilized through hydrogenated lecithin and sorbitan sesquioleate, an outer water phase contains tranexamic acid, a layered gel network is constructed, and the tranexamic acid-glutathione-containing compound emulsifiable paste is prepared. A submicron dispersion system with the particle size D50 of 0.30-0.80 microns, the polydispersity index of 0.15-0.25 and the viscosity of 2.0-8.0 Pa seconds is realized, the encapsulation efficiency of glutathione is not lower than 70%, the oxygen content of a head space is not higher than 1.0%, and the encapsulation efficiency of glutathione is not lower than 70%. The three technical contradictions of coupling conflict between a high-yield viscoelastic structure and low-shear damage kernel integrity, coexistence of fresh and cool low-viscosity skin feeling and high-barrier anti-oxidation and anti-leakage and opposite low-surface-activity sensitive skin compatibility and submicron low-PDI dispersion stability are solved; the traditional Chinese medicine composition has wide application values of improving skin color unevenness, fading color spots, brightening skin color, soothing and repairing.

The invention discloses multi-response microgel with an ultrathin shell layer and a preparation method of the multi-response microgel, and relates to the technical field of gel. The preparation method comprises the following steps: preparing an inner oil phase, a middle water phase and an outer oil phase; respectively injecting the inner oil phase, the intermediate water phase and the outer oil phase into a microfluidic device to obtain O / G / O type double emulsion microgel; and carrying out a cross-linking reaction on the double emulsion and a cross-linking agent, thereby obtaining the product. According to the preparation method disclosed by the invention, the O / G / O type double-emulsion microgel with a core-shell structure is successfully prepared by taking corn oil, gelatin and sodium alginate as main raw materials by adopting a micro-fluidic technology, so that the embedding rate of a target object can be improved, and active adsorption and embedding of active substances are realized; the emulsion microgel is further subjected to cross-linking modification, through cross-linking modification, the stability and strength of the O / G / O type double emulsion microgel structure after swelling adsorption are improved, the shell layer of the microgel is converted into a nano-scale thin film from a micron-scale thin film, and the multi-response microgel with an ultrathin shell layer is formed.

The invention relates to the technical field of colloid and interface chemistry, in particular to an oil-in-water-in-oil double emulsion, a one-step preparation method of the oil-in-water-in-oil double emulsion and application of the oil-in-water-in-oil double emulsion. A water phase and an oil phase are sheared and stirred at a high speed of 6000-12000 r / min through a one-step process to form an emulsion with a droplet diameter of 1-100 [mu] m. According to the invention, the tedious process of respectively stabilizing the inner and outer oil-water interfaces of the double emulsion through two emulsifiers with different hydrophilic and oleophylic properties in a traditional two-step method is effectively improved, and the O / W / O double emulsion is directly obtained through a one-step process, so that the purpose of simultaneously stabilizing the inner and outer emulsion interfaces of the double emulsion through a single emulsifier is achieved; the method has a huge potential application prospect in the fields of food packaging, drug sustained release and the like.

The application discloses an incubation method of self-assembled organic material crystals based on double emulsion drops, and the method comprises the following steps: preparing W / O / W type double emulsion drops with uniform size through a microfluidic chip; during the preparation of the double emulsion drops, using a self-assembled organic material solution as an inner water phase solution, using a non-water-soluble solution as an intermediate oil phase solution, and using a water phase solution containing a high salt concentration as an outer water phase solution to encapsulate the self-assembled organic material solution, so as to avoid the self-assembled organic material from being free in the outer water phase solution; and incubating the double emulsion drops loaded with the self-assembled organic material solution. By using the concentration difference between the outer water phase solution and the inner water phase solution, under the influence of osmotic pressure, water molecules in the inner water phase solution migrate to the outer water phase, and the concentration of the self-assembled organic material in the double emulsion drops also increases, so as to promote the growth of the self-assembled organic material crystals, and finally, the self-assembled organic material crystals with uniform size are obtained in the double emulsion drops, and each double emulsion drop contains a single self-assembled organic material crystal.

This invention discloses a method for preparing hydrophilic drug nanoliposomes based on microfluidic-low-shear coupling double emulsion and the hydrophilic drug nanoliposomes prepared according to the following method: (1) Prepare aqueous solutions of hydrophilic drugs and chloroform solutions of soybean lecithin respectively; (2) Add the chloroform solution of soybean lecithin to the chamber as the oil phase, and inject the aqueous solution of hydrophilic drugs into the oil phase in the low-shear stirring field through a microtube under low-speed stirring and shearing, and collect the W / O pre-emulsion sample; (3) Use the W / O pre-emulsion sample as the dispersed phase, and inject it into the external aqueous phase in the same way as in step (2), and emulsify it under low-speed stirring and shearing to form a W / O / W double emulsion; (4) Remove the chloroform by vacuum evaporation of the W / O / W double emulsion to obtain hydrophilic drug nanoliposomes. The prepared Ganoderma lucidum polysaccharide nanoliposomes have a particle size controlled at 200-300 nm, a polydispersity index of about 0.2, and an encapsulation efficiency of more than 70%, which is more than twice that of the traditional thin film hydration method. It solves the technical problem of low encapsulation efficiency of water-soluble macromolecular Ganoderma lucidum polysaccharides.

The present invention discloses a method for preparing cationic hyaluronic acid microspheres, as well as the resulting products and applications. The method prepares hyaluronic acid polyester microspheres by a water / oil / water double emulsion solvent volatilization method, then introduces amino groups onto the microsphere surfaces through an aminolysis reaction to construct cationic hyaluronic acid microspheres. The microspheres are then applied to moisturizing finishing of textile fabrics. The cations of the microspheres and the anions on the surface of the fabric fibers form an electrostatic force, strengthening the bonding between the microspheres and the fabric, improving the washability of hyaluronic acid textiles, and resolving the problem of hyaluronic acid textiles being unable to retain moisture over the long term.

The application belongs to the field of food functional factor processing, and particularly relates to a water-in-oil-in-water composite emulsion embedding lactoferrin, a preparation method and application. The W1 / O / W2 double emulsion system is constructed by a two-step method, and the leakage and inactivation risks of lactoferrin and VD3 in the preparation, storage and processing processes are effectively reduced through the double barrier effect of the oil phase film and the outer water phase film. Under the optimized sodium caseinate and gellan gum compounding conditions, the encapsulation rate of lactoferrin can be up to 82.52%, which proves that the structure has obvious advantages in improving the loading efficiency of active substances, and can significantly improve the encapsulation rate and structural stability of lactoferrin. The water-in-oil-in-water composite emulsion system prepared by the application can significantly improve the retention rate of lactoferrin in the digestion process, enhance the tolerance of lactoferrin to the gastrointestinal environment, and then enhance the arrival rate of lactoferrin in the intestinal tract, thereby improving the overall bioavailability.

The invention discloses a preparation method and application of PLGA (poly (lactic-co-glycolic acid))-curcumin nanoparticles. The invention relates to the technical field of biomedicine, and the preparation method comprises the following steps: taking a polyvinyl alcohol (PVA) aqueous solution as a water phase and a dichloromethane solution of polylactic acid-glycolic acid copolymer (PLGA) and curcumin (Cur) as an oil phase, preparing curcumin-entrapped PLGA nanoparticles (PLGA at Cur NPs) by adopting a water-in-oil-in-water double emulsion method, and the prepared PLGA nanoparticles are spherical, uniform in particle size and uniform in particle size. The carrier PLGA has good biocompatibility and biodegradability and is non-toxic and non-irritant, and a surfactant does not need to be added in the preparation process of the nanoparticles, so that the toxicity is further reduced.

The preparation method of the antimony trioxide with the porous structure comprises the following steps: adding an antimony trioxide matrix into a montmorillonite loading agent which is 5-8 times of the total amount of the antimony trioxide matrix, stirring, carrying out suction filtration, and drying to obtain the antimony trioxide with the porous structure. An antimony trioxide matrix is constructed by adopting a double emulsion template method, meanwhile, montmorillonite is pretreated, interlayer water is damaged by preheating at 210-230 DEG C, then the temperature is increased to 350 DEG C, heat preservation is performed for 1 h, an interlayer structure is stripped through thermal expansion, the specific surface area is increased, more active sites are exposed, and the specific surface area is increased. And dopamine / carbon nanotube composite modification: dopamine hydrochloride is subjected to self-polymerization under a weakly alkaline condition to form a polydopamine (PDA) coating layer.

The present invention discloses a method and device for preparing large-sized microspheres with uniform particle size and regular shape, which relates to the field of emulsion preparation technology, including: preparing a double emulsion microsphere material containing an inner phase, an intermediate phase and an outer phase, wherein the inner phase includes an aqueous solution containing an active ingredient and a hydrophilic polymer surfactant, and the intermediate phase includes a melting point of 50°C. <T 熔 The oil phase and lipophilic nonionic surfactant at a temperature of <85°C, the external phase is an aqueous solution, or a single emulsion microsphere material is prepared; the material is then passed into the microfluidic chip for molding, and the microsphere molding temperature is T 熔 + (10~15) ℃; the formed microspheres are cured by gradient cooling in the liquid outlet tube or the formed microspheres are directly dropped into the receiving liquid for curing. The receiving liquid temperature is (T 熔 ‑30)~(T 熔 ‑5) ℃; the preparation method of the present invention ensures stable microsphere molding, low probability of microsphere demulsification and irregular shape, and the prepared large-sized microspheres have uniform particle size and regular morphology.

This invention belongs to the field of fire extinguishing materials and their preparation technology, and provides a fire extinguishing microcapsule and its microfluidic controllable preparation method. The preparation method is characterized by the following steps: (1) preparing fluids of each phase, (2) preparing a dual emulsion using a microfluidic device, (3) collecting and sealing the dual emulsion in a collection container, controlling the axis of the collection container to be horizontal, and controlling the collection container to rotate around its axis for 1 to 15 minutes, applying light to solidify the outer shell of the dual emulsion droplets while maintaining the rotation of the collection container, cleaning, and drying to obtain the final product. The fire extinguishing microcapsule prepared by this method consists of an outer shell and a liquid fluorine-containing fire extinguishing agent encapsulated within the outer shell. The outer shell of the fire extinguishing microcapsule has a uniform thickness, and the eccentricity between the outer shell and the core is less than 0.1. The method of this invention can achieve precise customization of fire extinguishing microcapsules according to the differentiated fire characteristics of different application scenarios, and can improve the concentricity between the core and the outer shell of existing fire extinguishing microcapsules.

The application relates to the embedding technical field, and particularly discloses a double emulsion gel bead embedding beta-carotene and probiotics and a preparation method thereof. The double emulsion gel bead comprises a composite layer, an oil phase and an inner water phase from outside to inside. The composite layer comprises an outer water phase and calcium alginate which are fused with each other. The outer water phase comprises a product after carrageenan and sodium caseinate are subjected to a Maillard reaction. The oil phase comprises beta-carotene, vegetable oil and a food emulsifier. The inner water phase comprises probiotics. In the gel bead, the beta-carotene and the probiotics are simultaneously embedded in the double emulsion gel bead, the calcium alginate hydrogel shell starts to decompose when entering the intestinal tract, then the double-layer emulsion is slowly decomposed after being subjected to chemical digestion of pancreatic juice, bile and small intestinal juice and mechanical digestion of the small intestine in the small intestine, and the beta-carotene and the probiotics are gradually released, the beta-carotene is converted into vitamin A in the intestinal tract and is absorbed, and the probiotics are delivered to the colon to play a probiotic effect.

Systems and methods for measuring osmotic pressure are described. In many embodiments, double emulsion droplets can be used as osmotic pressure sensors to measure local osmotic pressure. The double emulsion droplets can measure osmotic pressure in living cells and / or tissues.

The invention belongs to the technical field of food processing, and particularly relates to ultrasonic phosphoric acid acetylated mung bean protein as well as a preparation method and application thereof. According to the ultrasonic phosphoric acid acetylated mung bean protein preparation method provided by the invention, the mung bean protein is prepared by utilizing the combined action of three methods of ultrasonic assistance, phosphorylation modification and acetylation modification; the emulsifying activity of the prepared ultrasonic phosphoric acid acetylated mung bean protein reaches 149 mL / g and the emulsifying stability reaches 75%; the double emulsion system prepared on the basis of the ultrasonic phosphate acetylated protein shows the following outstanding properties: the average particle size of liquid drops is as low as 0.6 mu m, the entrapment efficiency is as high as 71%, the liquid drop distribution uniformity is remarkably improved, and meanwhile, the physical stability of the emulsion is effectively enhanced due to the moderate increase of the viscosity of the system.

The application discloses a preparation method and application of allulose-vanillin microcapsules, and comprises a double emulsion preparation step, an alternating current field treatment step and a spray drying step. By constructing a double water-in-oil-in-water emulsion, the problems of low solubility and poor stability of the material are solved, and the bioavailability of allulose and vanillin is improved. The allulose-vanillin microcapsules are prepared by using alternating current field superimposed spray drying, the adsorption and combination of allulose and vanillin molecules on the water-oil phase are strengthened, and the encapsulation rate and the retention rate of vanillin are effectively improved. The preparation method provided by the application aims to reduce the sucrose content in food by using cross-modal interaction, realizes the goal of reducing sugar without reducing sweetness of food, solves the problems of insufficient sweetening effect and limited microcapsule embedding efficiency of flavor substances in the prior art, and has a wide market application prospect in the field of food processing.

Methods and systems for automated double emulsion droplet library generators are described herein. Optimizing the geometry and composition of double emulsion droplets is essential for maximizing their utility in various scientific and industrial applications. The microfluidic method is effective to generate a droplet library, which is useful to optimize droplets. However, monitoring and intervention by a human are necessary to generate droplet library. The disclosure provided herein presents an automated double-droplet library generator that utilizes a fine-tuned object detector and feedback control. The system autonomously produces libraries of single-core double emulsion droplets tailored to user-defined sizes, shell thicknesses, and solute concentrations.

A probiotic microsphere with in-situ proliferation, its preparation method and application. The microsphere is prepared by a two-step Pickering double emulsion method, encapsulating probiotics and panax notoginseng saponins, and then mixed with sodium alginate and cross-linked by calcium ions. The structure significantly improves the survival rate of probiotics in simulated gastric juice, intestinal juice, heat treatment and antibiotic environment, and maintains high viable cell count during long-term storage. Co-encapsulated PNS and double emulsion stabilizer natural polysaccharide-protein nanocomposite can promote the proliferation of probiotics in-situ, increase their activity. In addition, the microsphere can effectively promote the colonization and proliferation of probiotics in the intestinal tract, enhance the oral bioavailability of bioactive ingredients, and is suitable for functional food, feed, biological medicine field, especially as 3D printing special medical food for dysphagia population and prevention and treatment of intestinal inflammatory diseases.

The invention provides low-fat high-nutrition sesame milk and a preparation method thereof. The preparation method comprises the following steps: S1, preparing low-fat sesame meal and degreased sesame essential oil; s2, mixing the low-fat sesame meal with pure water, and grinding to obtain sesame primary pulp; adding tannase and phytase for enzymolysis to obtain enzymolysis sesame protein pulp, adding compound soybean protein, adjusting the solid content of a system, and homogenizing to form a uniform basic emulsion; s3, slowly injecting the core water phase into the intermediate oil phase, and shearing and emulsifying to form a W / O primary emulsion; slowly adding the W / O primary emulsion into the hydrogel outer layer, and refrigerating for 1-2 hours to form double emulsion gel microspheres; and S4, mixing the double emulsion gel microspheres with the basic emulsion, stirring for 10-15 minutes, sequentially adding a flavoring agent and a stabilizing agent, homogenizing, sterilizing at low temperature for 30 minutes, and quickly cooling to obtain the low-fat high-nutrition sesame milk. The problem that fat in the sesame milk is too high is solved, meanwhile, the natural flavor is reserved, and the prepared product has the advantages of being low in fat, high in nutrition and good in taste.

The invention relates to the technical field of epoxy resin materials, and discloses a nano rubber epoxy resin flexibilizer double-emulsion stirring preparation method, which comprises: mixing an epoxy resin matrix, a liquid rubber component, a surfactant and a diluent to form a primary double-emulsion; the method comprises the following steps: acquiring a viscosity induction torque representing dispersion phase droplet breaking resistance in a stirring process, monitoring a torque change rate to judge a dispersion equilibrium state, triggering a rotating speed step factor to increase a stirring rotating speed according to the torque change rate, and realizing forced regulation and control on dispersion phase particle size distribution by increasing shear stress; overlapping an oscillation shear field and cooperating with reverse stirring to induce an interface anchoring component to be spread and implanted at a phase interface to construct a chemical anchoring layer. According to the method, viscosity drift caused by temperature rise is compensated through torque feedback, the shear energy level is maintained to be constant, and the consistency of nanophase particle size distribution is ensured; a chemical anchoring structure is formed by utilizing an oscillation shearing induced phase interface, an infiltration dead zone is eliminated, the two-phase bonding strength is enhanced, and the service reliability of the material is improved.

The application belongs to the technical field of petroleum fracturing proppant preparation, and particularly relates to a preparation method of an in-situ self-grown core-shell structure double-repellent micro-nano proppant double-emulsion fracturing fluid. The application uses sodium silicate, a silane coupling agent and ethyl lactate as proppant core material precursor materials, uses a thermosetting resin as a proppant shell layer precursor material, and uses double-repellent modification materials and a drag-reducing agent as precursor materials of the double-repellent surface, so that the cost is reduced, and the strength of the proppant and the flow permeation and drag reduction capacity thereof are improved.

The application provides a method for preparing hollow non-spherical micro-nanoparticles based on a coaxial micro-reactor, and belongs to the field of droplet microfluidics and polymer materials. A three-channel coaxial micro-reactor is designed to generate a water-in-oil-in-water (W / O / W) double emulsion. The innermost phase is an alkaline electrolyte aqueous solution, the intermediate oil phase is a polymer solution, and the outermost phase is a surfactant aqueous solution. With the volatilization of the intermediate phase solvent, the double emulsion droplets form hollow non-spherical micro-nanoparticles. The double emulsion is placed in a collection liquid with different electrolyte concentrations, water molecules in the collection liquid penetrate into the innermost phase under the action of osmotic pressure, increase the size of the inner droplets of the double emulsion, and then change the morphology of the outer droplets, so that the non-spherical structure required is presented, and the size of the hollow micro-nanoparticles is controllable. The coaxial micro-channel reactor used in the application adopts a flow focusing structure, which is used for controllable generation of double emulsion to prepare multi-chamber hollow non-spherical micro-nanoparticles.

The invention discloses plant-based latte coffee rich in anthocyanin and soybean isoflavone aglycone and a preparation method of the plant-based latte coffee, and belongs to the technical field of functional coffee drinks. The preparation method of the plant-based latte coffee comprises the following steps: adding lecithin and an acai berry powder water-soluble substance into medium chain triglyceride, shearing and emulsifying to obtain a lecithin emulsion; high-aglycone-content soybean milk obtained after enzymolysis of beta-glucosidase is mixed with lecithin emulsion, mung bean protein and inulin are added, shearing emulsification and homogenization are performed, chlorogenic acid and vanillin are added, stirring reaction is performed to obtain double emulsion, then the double emulsion is added into coffee extraction liquid, foaming is performed, and the plant-based latte coffee is obtained. The stability of the plant-based latte coffee in an acidic coffee environment (pH 5.0) is remarkably improved, the plant-based latte coffee has the color and milk foam volume similar to those of traditional cow milk-based coffee, the stability similar to that of traditional milk latte coffee, and the overall sense is superior to that of traditional plant-based latte coffee.

The invention belongs to the technical field of daily chemical products, and particularly relates to a scalp oil control composition containing tea polyphenol as well as a preparation method and application of the scalp oil control composition. The composition comprises the following components in percentage by mass: 10%-50% of vegetable fat, 0.01%-15% of a water-in-oil emulsifier, 0.01%-15% of an oil-in-water emulsifier, 0.001%-5% of tea polyphenol modified nanoparticles and the balance of water. According to the invention, the water-in-oil emulsion is used as a basic form, and the tea polyphenol modified nanoparticles are used as an internal phase, so that the stability of tea polyphenol is effectively improved; meanwhile, an oil-in-water emulsifier is added for modification, so that the emulsion forms a water-in-oil-in-water (W / O / W) dual-emulsification structure, and the problem of poor solubility of the water-in-oil emulsion is solved. In addition, through the synergistic effect of all the components, the scalp oil-control shampoo can effectively adjust scalp water-oil balance, and an excellent scalp oil-control effect is achieved; meanwhile, a good moisturizing effect is achieved, and the dual advantages of oil control and mild nursing are achieved.

The invention discloses a preparation method of taurine-enhanced beef soup with taurine embedded by double emulsions. The preparation method comprises the following steps: step (1), extracting and enriching taurine in bovine by-products; step (2), preparing double emulsions embedded with the taurine extract; (3) adding double emulsions into the beef soup, and sterilizing; and (4) measuring the sense organ and the taurine storage amount after sterilization. The obtained ready-to-eat beef soup product contains taurine which is several times higher than that of common beef soup, the ready-to-eat beef soup is taurine-enhanced beef soup, and the double-emulsion embedding technology can remarkably mask flavor damage caused by addition of high-concentration taurine to the beef soup; meanwhile, the loss of taurine caused by high-temperature sterilization can be obviously reduced. The taurine is extracted from bovine by-products, and compounds used for preparing the double emulsion are all food-grade natural sources and are safe and harmless.

The present invention provides micro- to milli-meter sized polymer encapsulated inorganic salt PCM and PCM gel composite spheres for high thermal energy storage, minimal subcooling, high thermal stability, no phase segregation, and high thermal conductivity using double emulsion synthesis techniques. The encapsulated PCM invention addressed the common issues encountered such as subcooling, leakage, instability, and poor thermal energy density. An innovation of the present art is in the constituents which make up the invention being low cost, safe and environmentally friendly. Inclusion of graphene oxide in the encapsulated PCM invention results in enhanced thermal conductivity and up to 33% subcooling reduction. Applications of the invention are in the building envelope, integrating with cooling / heating equipment (HVAC, refrigeration, water cooling) and building materials (insulation, ceiling, roof, flooring, drywall, paint), the aerospace and textile industry, and the transport and storage of biological materials, organs, medicines, chemicals, food and drink, and other temperature-sensitive materials.

The invention discloses a microfluidic large-scale manufacturing method and microfluidic large-scale manufacturing equipment for monodisperse double emulsions, and relates to the technical field of microfluidics. Flow parameters are decoupled through a multi-interface collaborative pinch-off mechanism in a stepped emulsification microfluidic unit; therefore, the influence of non-uniform distribution of fluid in a parallel stepped emulsification microfluidic network on the monodispersity of liquid drops is avoided, and large-scale manufacturing of the monodisperse double emulsion is realized through parallel connection and modular integration of a plurality of stepped emulsification microfluidic units. According to the micro-fluidic large-scale manufacturing method and equipment for the monodisperse double emulsion, the problem that the monodispersity of liquid drops is reduced due to non-uniform flow resistance distribution in parallel channels can be avoided, parallel mass production of the double emulsion with 1000 channels can be realized through parallelism of 100 stepped emulsification micro-fluidic units and integration of 10 modules, and the production cost is reduced. And the manufacturing flux can reach 1.8 L / h.

The invention provides a surface modification method and system for a double-emulsion-drop micro-fluidic chip, and relates to the technical field of micro-fluidic chips, the method comprises the following steps: carrying out plasma treatment on a substrate and a substrate with a micro-channel, carrying out hydrophilic modification on the surface of the micro-channel, and packaging; a hydrophobic reagent is conveyed to a to-be-hydrophobic area in the microchannel for local hydrophobic modification in a positive pressure driving mode by adopting a pumping device; after local hydrophobic modification, a cleaning reagent is introduced into the micro-channel, the residual hydrophobic reagent is washed, gas is introduced for blow-drying, and the double-emulsion-droplet micro-fluidic chip subjected to local hydrophilic and hydrophobic treatment is obtained. Compared with the prior art, the scheme does not need additional complex instruments and tedious steps, only needs several minutes from treatment to double-emulsion droplet generation, is adaptive to micro-fluidic chips with different flow channel sizes, shapes and focusing angles, can enable an inner phase solution, an intermediate phase solution and an outer phase solution to stably occupy corresponding channels, and remarkably improves the stability and duration of double-emulsion droplet generation.