12 results about "Small droplet" patented technology

The invention belongs to the technical field of microfluidics, and particularly relates to a microfluidic chip and a method for preparing liquid drops in a high-flux and large-scale manner. A step emulsification structure and a liquid drop splitting structure are used together, a liquid drop generation structure is arranged at the communication position of a branch splitting channel and a main channel unit correspondingly communicated with the branch splitting channel, a dispersion phase necks at the liquid drop generation structure under the action of interfacial tension to form liquid drops, and the liquid drops are generated under the leading of the interfacial tension, so that the dispersion phase is uniform in dispersion. Therefore, the size of the liquid drops is basically determined by the channel width of the liquid drop generation structure, the branch splitting channel is designed to be wide, the influence of manufacturing errors on the uniformity of the generated liquid drops can be reduced, the branch splitting channel is designed to be a plurality of serpentine channels, and the uniformity of the liquid drops is improved while high-flux liquid drop preparation is guaranteed; and then the liquid drops flow through the main channel unit and are converged into the main splitting channel, and the liquid drops are uniformly split into liquid drops with smaller sizes through the liquid drop splitting structure, so that the preparation of the liquid drops with high flux and uniform sizes is realized.

A droplet delivery device includes an ejector plate the produces a stream of droplets having a first large droplet size from a liquid supplied to the ejector plate and an impingement member that is positioned perpendicular to or at another non-parallel angle relative to an initial aerosol stream path produced from the ejector plate such that the one or more impingement members impinge the aerosol stream and reduce the size of droplets from the first larger size to one or more smaller droplet sizes.

A method for forming an array of droplets by repeatedly splitting of a large droplet into smaller droplets. The method involves taking one or more large droplets and repeated splitting in multiple dimensions to form an array of smaller droplets within the original area of the array.

A method of aerosol generation includes operating an electronic transducer at a second higher frequency than a first lower frequency with a same fluid composition and same ejector mechanism mesh with a predetermined hole size and generating smaller droplets at the second higher frequency.

1. Name of the designed product: secondary throwing bottle (small water droplet pointed secondary throwing). 2. Use of the designed product: used for liquid packaging. 3. Design points of the designed product: in shape. 4. Picture or photo that best shows the design points: design 1 perspective view. 5. Design 1 rear view is symmetrical with design 1 front view, and design 1 rear view is omitted; design 1 right view is symmetrical with design 1 left view, and design 1 right view is omitted; design 2 rear view is symmetrical with design 2 front view, and design 2 rear view is omitted; design 2 right view is symmetrical with design 2 left view, and design 2 right view is omitted. 6. Design 1 is designated as the basic design.

The disclosure provides systems and methods for droplet processing. For example, a method can include providing a first droplet and a second droplet. In some cases, the first droplet may have a first concentration of a reagent and the second droplet may have a second concentration of the reagent. The second droplet may comprise a bead or a biological particle. The method can also include subjecting the first droplet and the second droplet to conditions sufficient to transfer the reagent from the first droplet to the second droplet, thereby decreasing the first concentration in the first droplet and increasing the second concentration in the second droplet.

The present disclosure relates to an aerosol delivery device comprising a liquid supply, an electronically actuated droplet ejector in fluid communication with the liquid supply, and a filter medium or inertial filtering point between the ejector and a droplet outlet to reduce the droplet size distribution of the ejected droplets to smaller droplets exiting the droplet outlet.

An ejector mechanism of a droplet delivery device includes a piezoelectric actuator coupled to an acoustic horn and an aperture plate including a plurality of openings. At least the fluid entrance side of one or more of the plurality of openings is configured to provide a surface contact angle of less than 90 degrees and the piezoelectric actuator is operable to oscillate the aperture plate at a frequency to thereby generate an ejected stream of droplets such that at least about 50% of the droplets have an average ejected droplet diameter of less than about 6 microns during use. A sealing mechanism is provided at an interface of the aperture plate and a detachable fluid cartridge.

A droplet deflector with an optimized deflector plate is provided. A droplet deflector of interest includes a droplet deflector having a deflection plate configured for high angle deflection of a droplet flow stream. The droplet deflector of interest also includes a droplet deflector having a deflection plate that includes a shape corresponding to the path of the deflected droplet flow stream, or is configured to apply a deflection force to the flow stream at a plurality of different angles. The droplet deflector of interest also includes a droplet deflector configured to apply a constant deflection force to the deflected droplet flow stream from a plurality of different lateral positions, including, for example, a position where the deflection plate is a segmented deflection plate. Flow cytometers with the subject droplet deflectors and methods of use and configuration or design thereof are also provided.

The invention discloses a droplet generation method based on a single-hole piezoelectric diaphragm. Under the driving circuit, the single-hole piezoelectric diaphragm generates periodic vibration, and the liquid forms a stable liquid jet flow through the micropores. The jet flow is spread in the air and impacts on the hydrophobic surface, and exists on the platform in the form of liquid drops under the action of surface tension, so that the small liquid drops are generated. By adjusting the driving voltage and the micropore diameter, the controllable and adjustable millimeter-level small liquid drops with high precision can be obtained. The method is simple in structure, small in size, capable of being miniaturized and integrated, and suitable for small droplet generation in an open type microfluid system.

The present application relates to a microfluidic device having an array of micro-pores that enables scalable and parallel multi-step reactions of droplets, and related methods of performing the reactions in two paired micro-pores of different sizes by a plurality of repeating capture cell units and sequential collection and fusion of the droplets. Droplets containing a desired substance or reaction reagent are input onto the microfluidic platform. Each aperture is configured to first capture a larger droplet, then repeatedly capture a smaller droplet, and then fuse the larger and smaller droplets. In some embodiments, this action is facilitated by tilting the chip. In some embodiments, the larger droplets consecutively fuse three paired batches of smaller droplets containing various desired components while incubating between fusing and loading. In alternative embodiments, each capture well has two or more active capture sites, enabling simultaneous fusion of multiple smaller droplets and multiple fusion.