Microfluidic device capable of rapidly preparing emulsion in multiple dimensions

A microfluidic device, multi-dimensional technology, applied in the preparation of test samples, laboratory equipment, chemical instruments and methods, etc., can solve the problems of limited dimensions of emulsion splitting, complex channel processing of emulsion splitting devices, etc., and achieve the goal of building Fewer steps, increased emulsion yield, simple channel effect

Inactive Publication Date: 2016-09-07
SOUTHEAST UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0005] The technical problem to be solved by the present invention is to provide a multi-dimensional emulsion splitting and increase emulsion yield under the condition of ensuring the e...

Method used

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  • Microfluidic device capable of rapidly preparing emulsion in multiple dimensions
  • Microfluidic device capable of rapidly preparing emulsion in multiple dimensions
  • Microfluidic device capable of rapidly preparing emulsion in multiple dimensions

Examples

Experimental program
Comparison scheme
Effect test

example 1

[0034] Example 1: Using figure 1 The microfluidic device shown is implemented according to the implementation steps to realize the division of a single emulsion into two.

example 2

[0035] Example 2: Using figure 2 The microfluidic device shown is implemented according to the implementation steps, and the experimental single emulsion is divided into three.

example 3

[0036] Example 3: Using image 3 The microfluidic device shown is implemented according to the implementation steps, and the experimental double emulsion is divided into two.

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Abstract

The invention discloses a microfluidic device capable of rapidly preparing an emulsion in multiple dimensions. The microfluidic device comprises an internal phase capillary, an external phase capillary, a compression capillary and a split capillary, wherein the internal phase capillary, the external phase capillary, the compression capillary and the split capillary are coaxially arranged, the internal phase capillary is located at the inner front end of the external phase capillary, the compression capillary is located in the inner middle of the external phase capillary, the split capillary is located at the inner rear end of the external phase capillary, an emulsion forming section is reserved between the internal phase capillary and the compression capillary, and an inlet end of the split capillary is connected with an outlet end of the compression capillary. The preparation device provided by the invention has a simple channel and less construction steps and does not need complicated channel machining, single emulsion and double emulsions are split in multiple dimensions, the emulsion is split and the yield of the emulsion is improved under the condition that the yield and the homogeneity of the emulsion are guaranteed.

Description

technical field [0001] The invention relates to an emulsion preparation device, in particular to a glass capillary microfluidic device designed for increasing the output of the emulsion and having the characteristics of multi-dimensional, fast and uniform emulsion preparation. Background technique [0002] Emulsion is a highly structured fluid system, which can be divided according to different components: single emulsion with only one phase, double emulsion with two-phase nested structure, and multiple emulsion with more than two phases. Emulsions are widely used in drug release, drug delivery, biomaterials, biochemistry, and cosmetics industries. With the development of science and technology, the requirements for emulsion quality and output are getting higher and higher in production. Traditional emulsion preparation methods, such as stirring method, membrane emulsification, etc., will cause waste of raw materials, low preparation efficiency, and poor monodispersity of e...

Claims

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Application Information

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IPC IPC(8): B01L3/00G01N1/28
CPCB01L3/5027B01L3/502707B01L3/502715B01L3/502769B01L2300/0838G01N1/28
Inventor 赵远锦高崴张程宾陈永平
Owner SOUTHEAST UNIV
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