77 results about "Healthy population" patented technology

The invention discloses an electrocardiogram signal classification and recognition method. The method comprises the following implementation steps that original electrocardiogram waveform data with the measurement duration of 10 seconds or above is acquired, electrocardiogram rhythm information and a PQRST waveform are extracted according to the original electrocardiogram waveform data, and digitalized data of the electrocardiogram rhythm information and the PQRST waveform is acquired; a convolutional neural network is designed and constructed and trained, the acquired PQRST waveform data is input from the input end of the trained convolutional neural network, and type data is acquired through classification of the convolutional neural network. According to the method, by means of the fitting capacity of the convolutional neural network to a complex nonlinear function, more accurate and effective classification of ECG signals is acquired, so that high risk population, sub-healthy population and undetermined-condition population of cardiovascular diseases are monitored in real time, electrocardiographic changes in normal life, work and activities are intelligently analyzed to help determine condition or catch electrocardiogram information of potential cardiac diseases, and an early warning effect is made on a patient.

The invention disclose ganoderma lucidum kudzuvine root juice which takes ganoderma lucidum liquid and pueraria thomsonii benth as raw materials and comprises the following components: 30-200mg/L of pueraria isoflavone, 13.8-30g/L of ganoderma lucidum polysaccharide and not more than 50g/L of kudzuvine root powder; and meanwhile honey and glycyrrhizic acid can be also blended into the materials. The ganoderma lucidum kudzuvine root juice reserves puerarin, cellulose, protein and the like in the pueraria thomsonii benth maximally, lowers starch content as much as possible and transforms starch, protein and the like into ganoderma lucidium mycelium through fermentation, thus meeting the need of components for health of modern people; and meanwhile the honey and liquorice are added during the preparation process, thus being healthcare beverage which meets the healthcare need of modern sub-healthy population or alcoholic liver population.

The invention discloses a creative integrated evaluation system for life and health states, particularly a system mode for comprehensive and systematic checking and examination and analysis and assessment aiming at the life states of healthy population and sub-healthy population. At present, a health detection instrument is formed by a single detection technological principle, fox example, a meridian detection instrument, a bioelectlidty detection instrument, a thermal infrared imaging detection instrument and the like adopt the single detection principle. By using the technology of the invention, a set of multi-dimensional health measurement and analysis system integrated by a single measurement and analysis instrument is established and has high scientificity and strong stability. The system adopts the detection principle that a data result generated by the traditional health detection technology is integrated and analyzed by a core technology I through a life state data acquisition system, the integrated data are analyzed and assessed by using a core technology II through a life state quantitative analysis system and the integrated life state analysis and assessment result is given out according to ten systems of human body.

The invention provides a natural plant extract together with a preparation method and application thereof. The plant extract is prepared by being extracted from raw materials of grape skins, hawthorn fruits, seabackthorn fruits, barbary wolfberry fruits, lotus leaves, semen coicis, rhizoma polygonati, roots of thomson kudzuvine, sharpleaf galangal fruits, etc. with menstruum and finely processed. The preparation method can be divided into two kinds, a single extraction and a mixed extraction. The natural plant extract can effectively control the caloric intake absorption of organisms, reduce fat accumulation in the body and harm of over nutrition to organisms, decrease blood fat, purify blood, control blood sugar and interdict and reverse the development towards sub-health state, thus reducing the morbidity risk of diseases, such as hyperlipemia, hypertension, diabetes mellitus, coronary heart disease, adiposity, fatty liver, etc.; the natural plant extract is edible for healthy population to maintain health and for sub-health population to effectively interdict and reverse the development towards sub-health state and can also be applied to the preparation of the medicine treating hypertension, hyperlipemia, diabetes mellitus and other diseases through deep processing.

The invention provides a natural plant extract, a preparation method and the application. The invention is characterized in that: the natural plant extract is prepared by grape skin, haw apple, lotus leaf, medlar, sea buckthorn, fiveleaf gynostemma herb, pilose asiabell root, radix polygoni multiflori preparata and other materials, and the materials are processed solvent extract, machining and refining and then the natural plant extract is obtained; the preparation method comprises A individual extraction method and B mixed extraction method. The natural plant extract has the advantages of effectively controlling energy absorbing of bodies, reducing fat accumulation in vivo and reducing harm of overnutrition to bodies, reducing blood fat, purifying blood, controlling blood sugar, interdicting and reversing the development of sub-healthy state, reducing morbidity risk of hyperlipemia, hypertension, diabetes, coronary heart disease, fatness, fatty liver and other diseases, providing healthy population for eating to keep fit, also providing sub-healthy population for eating to effectively interdict and reverse the development of sub-healthy state, still being used to prepare the medicament for curing hypertension, hyperlipemia, diabetes and other diseases after deep processing.

The invention relates to an instant highland barley cereal for recuing cholesterol and a preparation method thereof. The invention aims to provide an instant barley cereal with an auxiliary cholesterol-reducing health care function and a preparation method thereof. The invention has the technical scheme that the highland barley cereal comprises the following manufacturing raw materials: raw cereal, white granulated sugar, powdered oil, phytosterol, powdered milk, malt extract and milk powder essence, wherein the raw cereal comprises the following manufacturing raw materials: highland barley flour, wheat flour, rice flour, corn flour, white granulated sugar and salt. The invention is suitable for auxiliary therapy for patients with hyperlipemia and atherosclerosis, and is also suitable forpreventing cardiovascular disease for healthy population.

The invention provides original-flavored coarse grain nutritional powder and a preparation method thereof. The preparation method comprises the following steps: raw material selecting, stir-fried yellow millet powder preparing, black soybean powder preparing, chenopodium quinoa powder preparing, material mixing and packaging. A formula comprises the following components in parts by weight: 1-3 parts of yellow millet puffed powder, 1-3 parts of stir-fried yellow millet powder, 2-5 parts of corn puffed powder, 0.2-1 part of pumpkin powder, 1-3 parts of black soybean powder, 0.2-1 part of tartarybuckwheat powder, 0.2-1.5 parts of chenopodium quinoa powder, 1-2.5 parts of maltodextrin, 1-2.5 parts of xylitol and 0.2-1 part of inulin. The fully nutritional light-weight meal replacement powderaims at improving body constitution of sub-healthy populations, has effects of improving human body's high blood lipids, high blood sugar and high blood pressure, and is balanced in nutrition, delicate in taste and a comprehensive and balanced nutritional supplement food meeting diet philosophy of modern people.

The invention belongs to the technical field of food processing and discloses nutrition-balanced instant health-preserving rice and a preparation method thereof. The health-preserving rice is prepared from the following raw materials in percentage by mass: 20-25% of rice, 3-8% of millets, 3-8% of soybeans, 5-8% of corn grains, 5% of Chinese yams, 5% of coix seeds, 5% of wheat, 5% of bearded tooth mushroom, 5% of carrots, 5% of cassava, 4% of euryale ferox seeds, 3% of kudzuvine roots, 2% of poria cocos, 2% of walnut kernels, 1% of dried orange peels and 20-23% of water. The preparation method of the nutrition-balanced instant health-preserving rice comprises the following steps: crushing the raw materials; mixing the crushed materials and conditioning the mixed materials; carrying out extruding so as to granulate the conditioned material; carrying out baking so as to shape the granules; and cooling the shaped granules and packaging the cooled granules. The health-preserving rice satisfies the basic requirements of 'diversified foods on basis of cereals' in the Dietary Guidelines for Chinese Residents, and is free of addition of any chemical additives. The health-preserving rice can be eaten after being brewed with hot water of which the temperature is 80 DEG C or above for three minutes; and the brewed health-preserving rice is similar to a rice porridge, and is golden in color and luster, refreshing in taste and mutually complementary in nutrients. The nutrition-balanced instant health-preserving rice is a meal-replacement food suitable for modern sub-healthy populations, and has wide market prospects and promotion values.

The invention provides a substitutional tea of an elderberry leaf, which has a health-care function and is convenient to take, and a preparation method of the substitutional tea. The method comprises the following steps of airing until the moisture content of the leaf is 68-70% after cleaning picked elderberry leaf; putting into a water-removing machine to remove moisture, wherein the water-removing temperature is 150-250 DEG C, airing and cooling after removing moisture, drying in a dryer until the moisture content of the leaf is 5-9% after rolling, wherein the drying temperature is 80-120 DEG C, and preparing the substitutional tea of the elderberry leaf in inspecting and packaging manners. The substitutional tea of the elderberry leaf disclosed by the invention is convenient to take, not only can improve the patient conditions of diabetes mellitus, dyslipidemia and hypertensive patients, but also can be used as a green health food to increase the health of healthy population. Thus, multiple effects of increasing the bone mineral density, enhancing the immunity, antioxidation and the like are achieved.

The invention provides a detection method and application of a biomarker for detecting the cerebral apoplexy incidence risk and the cerebral apoplexy incidence based on the tyrosine level of a body fluid. The method comprises the following steps: 1, detecting the tyrosine concentration of exosome in a sample; 2, comparing the tyrosine concentration in step 1 with the tyrosine concentration result of known cerebral apoplexy patients, cerebral apoplexy high-risk populations and healthy populations; and 3, completing the detection method based on the tyrosine level of the body fluid as the biomarker for detecting the cerebral apoplexy incidence risk and the cerebral apoplexy incidence according to the above obtained comparison result. The content of tyrosine in exosome, such as urine, sweat and saliva, of the body fluid of cerebral apoplexy incidence or high-risk population is detected in order to predicate and detect the cerebral apoplexy incidence. The tyrosine level is positively correlated to the cerebral apoplexy incidence and the cerebral apoplexy risk.

The invention belongs to the field of medicine, and relates to an assessment system for assessing brain ageing through eye movement and body swing. Eye movement inspection equipment is adopted for thesystem to acquire eye movement data. Eye movement data of healthy population is used to establish a math model through a data manager. The system can further comprise a body oscillometer which is used for acquiring body swing data. According to the assessment system, a model which takes simple and quick quantitative eye movement data and body swing data as the basis and reflects that the functionof the nervous system of the human is continuously changed with age is first provided, data of testees is integrated to an eye movement inspection value distribution chart, predicted by the model, ofold people at different age groups, and the illness conditions of individuals are predicted; the problems of late discovery and difficult diagnosis of degenerative diseases of the nervous system aresolved, the system helps to diagnose and treat the degenerative diseases in the early stage and benefits patients and their families to a certain degree, and the social economic burden brought by thediseases is reduced.

The invention discloses a preparation method of red date and rhizoma dioscoreae health care jelly. The red date and rhizoma dioscoreae health care jelly is prepared from the following raw materials inparts by weight: 5 to 15 parts of fructus jujubae, 5 to 15 parts of rhizoma dioscoreae, 5 to 12 parts of lily bulbs, 5 to 10 parts of semen euryales, 5 to 10 parts of mulberry fruit, 5 to 7 parts ofpericarpium citri reticulatae, 0 to 20 parts of sweetening agents, 0.3 to 1 part of carrageenan, 0.3 to 1 part of locust bean gum and 0 to 0.05 part of potassium sorbate. The health care jelly provided by the invention remains natural flavor of traditional Chinese herbal medicine of red dates and the like; the health care jelly can be eaten immediately after the bag is opened; the carrying is convenient; the effects of invigorating the spleen, regulating the middle warmer, nourishing yin, moisturizing the lung, clearing away the heart-fire from the heart, soothing the nerves, supplementing kidney to control the vital essence and warming and tonifying the five internal organs are achieved; the good effect of improving the immunity is achieved; the health care jelly can be eaten by old and weak people or children with weak spleen and stomach function and people with liver and kidney deficiency, and can also be used as health care products for daily conditioning of sub-healthy population.

The invention provides a biomarker for early diagnosis of primary hepatocellular carcinoma as well as a detection reagent and application of biomarker, and belongs to the technical field of liver cancer diagnosis. According to the invention, bacterial DNA is extracted from an excrement sample of a detected object by a 16S rRNA sequencing method; then, Illumina Miseq sequencing is carried out; intestinal biomarkers for early liver cancer and healthy control are identified; furthermore, a random forest model for specifically identifying early liver cancer and healthy population samples is established through the biomarkers; a fitting condition of a learning curve evaluation model is drawn; the effect of the model is evaluated through a receiver operating characteristic curve; the area under the curve of the prediction model is 0.95; the precision of the test result is 0.97; the recall rate is 1.0; and the specificity is 0.98. Therefore, the biomarker, the built random forest training model and the detection method in the invention have a good market prospect in early diagnosis of liver cancer.

The invention discloses a sub-health quantitative evaluation system based on meridian and collateral balance and relates to the technical field of medical equipment. A relative resistance value of skin resistance between Jing-well acupoint of left-right 12 main meridian and Panggong acupoint on the opposite side is measured, deviation degree of a single meridian and deviation degree of the meridian relative to overall level are calculated through a weighted statistics algorithm based on traditional Chinese medicine meridian theory, deviation degree of individual and healthy population is calculated through a big data method, total deviation degree is calculated finally to reflect human body unbalance state, and human body sub-health degree is directly embodied through the data; sub-healthlevel can be evaluated directly and quantitatively through meridian skin resistance characteristics, a certain meridian can be located to prompt the qi-blood level problem that corresponding viscera may have, guiding suggestion can be provided for disease prevention, and the whole operation process is noninvasive, simple and easy to implement, easy for further integration and intelligentization and even capable of realizing real-time monitoring.

Method for diagnosis of inflammatory conditions in the intestinal canal of humans, characterized in that NO is measured in the lumen of the intestines. The NO level obtained is then compared with the level obtained for healthy individuals or with the level obtained for the same individual at another occasion. An increased level compared to the normal levels in the intestines of the healthy population is an indication of an inflammatory condition in the intestine.

The invention discloses a method and a device for detecting copy number variation and a storage medium. The detection method comprises the following steps: acquiring DNA sequencing data of a to-be-detected sample and comparison data of the DNA sequencing data at each position on a human reference genome; counting the depth of the DNA of the sample to be detected in the fixed window area; extracting a data sequence with abnormal comparison as a first dimension result supporting copy number variation; extracting a window of which the depth is different from that of the distribution statistical model of the DNA window of the to-be-detected sample; judging whether the difference of the difference window is significant or not and whether a first dimension result support can be obtained or not;and outputting a detection result. According to the detection method, true and false copy number variation can be accurately distinguished through the distribution statistical model of the DNA of a healthy population, and the accuracy of the copy number variation detection result is ensured from different perspectives in combination with the result of another dimension. According to the detectionmethod, no genetic control sample is needed, and copy number variation detection can be carried out on a single sample.

The invention discloses Chinese-yam polygonatum-sibiricum effervescent tablets and a preparation method thereof. The Chinese-yam polygonatum-sibiricum effervescent tablets are prepared from the following raw materials and auxiliary materials in parts by weight: the raw materials comprising 50-70 parts of Chinese yams, 50-70 parts of polygonatum sibiricum, 25-35 parts of Chinese wolfberry fruits, 8-12 parts of raspberry fruits, 15-25 parts of poria cocos, 8-12 parts of fructus amomi, 8-12 parts of Chinese dates, 25-35 parts of radix polygonati officinalis, 8-12 parts of euryale ferox seeds, 8-12 parts of mulberry fruits, and 10-15 parts of liquorice roots; and the auxiliary materials comprising 40-50 parts of citric acid, 40-50 parts of sodium bicarbonate, 8-12 parts of micronized silica gel, 3-6 parts of bBifidus sugar, and 300-370 parts of mannitol. Multiple medicine-and-food-homologous traditional-Chinese-medicine raw materials are comprehensively used in the Chinese-yam polygonatum-sibiricum effervescent tablets, and thus, the prepared Chinese-yam polygonatum-sibiricum effervescent tablets are good in taste, and have the physiological activity functions of invigorating the liver and the kidney, strengthening the muscles and the bones, enhancing body immunity, calming the nerves, benefiting the intelligence, regulating the spleen and the stomach, and so on. The Chinese-yam polygonatum-sibiricum effervescent tablets have very good curative effects on sub-healthy population; moreover, the preparation method of the Chinese-yam polygonatum-sibiricum effervescent tablets is simple. The Chinese-yam polygonatum-sibiricum effervescent tablets can be taken for a long term.

The invention discloses a method for predicting the risk of non-alcoholic fatty liver disease by genetic polymorphism. According to the method, the risk of NAFLD in the population can be predicted. Based on the comparative analysis of genetic data of a large number of NAFLD population and healthy population in China, three polymorphic sites of TM6SF2 rs58542926, PNPLA3 rs738409 and TRBI rs17321515closely related to NAFLD susceptibility are selected, and the data are statistically analyzed to calculate the risk of NAFLD susceptibility genotype in Chinese population. The method has important guiding significance for prevention and treatment of the NAFLD, and is suitable for popularization and application.

The invention discloses a medical data mining method for preventive treatment of disease. According to the method of the invention, historical physical data of a patient with each disease are analyzed. A physical sign change trend model of the patient from a healthy state and a disease state is acquired. Then the trend model is used for tracking the physical sign data of healthy population. Once an individual which accords with the trend model is found, early-warning can be performed on him (her). The medical data mining method can realize effective identification to the change trend of physical sign data of the individual and early-warning. Furthermore the medical data mining method settles problems such as individual basic physical sign difference, different time sequence of the physicalsign data, random and periodical noise, etc. The method is applied in medical examination data screening of the healthy population and has advantages of realizing finding of the individual with disease potential as early as possible, improving preventing and treating effect, and reducing treating cost.

The invention discloses an ankylosing spondylitis microbial marker, which is formed by the following microbes: Actinomyces sp. ICM47, Bifidobacterium breve, Bifidobacterium sp.12_1_47 BFAA, Bifidobacterium longum, Collinsella aerofaciens, Bifidobacterium bifidum, Bifidobacterium pseudocatenulatum, Eggerthella lenta and Bifidobacterium catenulatum. Compared with healthy population, the ankylosing spondylitis microbial marker is obviously enriched in ankylosing spondylitis patient population, and can be used as a distinction marker of the healthy population and the ankylosing spondylitis patient population.

The present invention discloses a preparation method of functional sucrose having a sugar lowering function. The method comprises the following steps: sugar syrup or sugar syrup dissolved by solid sugar is clarified and the clarified syrup is finely filtered to remove precipitates and suspended matters to obtain a clear sugar syrup; bagasse and/or sugarcane tips are crushed, the crushed materials are soaked, and the soaked materials are extracted to obtain an extract; a colloid aqueous solution is added into the extract concentrate to prepare an extract dispersion liquid; the extract dispersion liquid is added into the clear sugar syrup to be stirred evenly to obtain a mixed sugar syrup of the extract and the clear sugar syrup; the mass ratio of total mass of total polyphenols and flavonoids in the mixed sugar syrup and the solid matter of the sugar syrup is 0.02% or above; and the liquid mixed sugar syrup is subjected to a crystallization transformation into solid sucrose and the medium-sized or microcrystalline functional sucrose having the sugar lowering function is prepared. The plant resources of the sugarcanes, sugar beet, etc. are fully utilized, a product sugar lowering active substance is an active phytochemical, and the functional sucrose has the characteristics of being purely natural and green, healthy and safe, is suitable for populations with diabetes, and also has prevention and health-care functions for healthy populations.

The invention discloses an ankylosing spondylitis microbial marker, which is formed by the following microbes: Actinomyces sp. ICM47, Bifidobacterium breve, Bifidobacterium sp.12_1_47 BFAA, Bifidobacterium longum, Collinsella aerofaciens, Bifidobacterium bifidum, Bifidobacterium pseudocatenulatum, Eggerthella lenta, Bifidobacterium catenulatum and Bifidobacterium adolescentis. Compared with a healthy population, the ankylosing spondylitis microbial marker is obviously enriched in an ankylosing spondylitis patient population.

Pulmonary embolism in a human patient can be detected or confirmed by monitoring the level of endogenous NO in expired air, comparing the measured level with baseline values previously obtained for the same patient or baseline values representing a healthy population. The method can be used alone, or as a supplemental or adjunct step in traditional methods for diagnosing pulmonary embolism. Analysis of the obtained NO value, with consideration of the flow and resistance, can be used to indicate the severity of the pulmonary embolism.

The invention belongs to the field of food processing, and in particular relates to a clinical nutritional meal replacement bar and a preparation method thereof. The invention aims to solve the technical problem by providing a clinical nutritional meal replacement bar. The clinical nutritional meal replacement bar is prepared by baking the following components: 80-120 parts of defatted soybean powder, 20-40 parts of egg, 0.5-1.5 parts of salt, 15-35 parts of lecithin, 10-30 parts of sorbitol, 5-25 parts of polydextrose, 5-15 parts of xylitol and 0.2-2 parts of ultramicro tea powder. The invention also provides a preparation method of the clinical nutrition meal replacement bar. The preparation method comprises the following steps: a, pretreatment of raw materials; b, mixing; c, molding; d, baking; and e, cooling. The clinical nutrition meal replacement bar provided by the invention is prepared from ultramicro defatted soybean powder, has better formability, lubrication and delicacy; and through scientific compatibility, the prepared clinical nutrition meal replacement is suitable for the patients with hyperglycemia and hyperlipidemia or healthy population for the prevention of hyperglycemia and hyperlipidemia.

The invention relates to a molecular marker for diagnosing idiopathic inflammatory myopathy and an application thereof. The molecular marker is an autologous heat shock factor 1 (HSF1) antibody in a serum. The antibody is IgG. The idiopathic inflammatory myopathy is polymyositis (PM) or dermatomyositis (DM). The diagnosis is to distinguish the idiopathic inflammatory myopathy from a healthy population or to predict a disease progress of the idiopathic inflammatory myopathy (IIM).