Preparation with selective whitening spot-removing efficacy and application thereof in cosmetics

A technology of whitening and freckle removal and cosmetics, which is applied in the intersection of bioengineering technology and chemical synthesis technology, and in the field of traditional Chinese medicine technology, can solve the problems of irritation and absorption and unsatisfactory synergistic whitening and freckle removal

Inactive Publication Date: 2014-04-09
SHAANXI HUIKANG BIO TECH CO LTD
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the simple formula is not satisfactory in terms of irrita

Method used

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  • Preparation with selective whitening spot-removing efficacy and application thereof in cosmetics
  • Preparation with selective whitening spot-removing efficacy and application thereof in cosmetics
  • Preparation with selective whitening spot-removing efficacy and application thereof in cosmetics

Examples

Experimental program
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Effect test

preparation example Construction

[0046] Examples 1-8 are the preparation recipes of functional raw materials of the present invention, see Table 1 for details.

[0047] The preparation of table 1 embodiment 1~8 efficacy raw material prescription

[0048]

[0049] Preparation method: Under strong alkali or strong acid conditions, a peptide bond reaction occurs at -85°C to 200°C to generate azalic acid oligopeptides, ascorbic acid oligopeptides, tranexamic acid oligopeptides, retinoic acid oligopeptides, kojic acid oligopeptides, and hydroxyl Acid oligopeptides, ellagic acid oligopeptides.

[0050] Examples 9-16 are the proportions of the penetrant formulations of the present invention, see Table 2 for details.

[0051] The proportioning of table 2 embodiment 9~16 penetrating agent prescription

[0052]

[0053] Preparation method: Mix the raw materials evenly according to the proportion.

[0054] Examples 17-26 are the formulations for the preparation of selective whitening and freckle-removing cosmet...

Embodiment 17～26

[0059] The selective whitening and spot-removing effect test of the cosmetics obtained in Examples 17-26:

[0060] Select 100 healthy and normal volunteer subjects, half male and half male, aged from 30 to 65 years old. Divided into 10 groups at random, 10 people in each group, compared with Examples 17 to 26 respectively.

Embodiment 27

[0062] The test population used it twice a day, once in the morning and once in the evening, only on the left half of the face, and a placebo without key ingredients on the right half of the face. Use for 30 days, corresponding to the left and right sides of the face.

[0063] Test results:

[0064] test population

[0065] The test results show that the prescription of the present invention has a good effect on selective whitening and freckle removal in a short period of time.

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Abstract

The invention provides a nutritional preparation with selective whitening spot-removing efficacy and application thereof in medicinal cosmetics. The nutritional preparation is prepared by compounding of azelaic acid oligopeptide, ascorbic acid oligopeptide, tranexamic acid oligopeptide, retinoic acid oligopeptide, kojic acid oligopeptide, hydroxy acid oligopeptide, ellagic acid oligopeptide and other raw materials, and the oligopeptide is one or a compound of multiple of dipeptide, tripeptide, tetrapeptide, pentapeptide, hexapeptide, heptapeptide, octapeptides, nanopeptide and decapeptide. The medicinal cosmetics prepared form the nutritional preparation are original liquids, water preparations, masks, cream lotion, liquid foundation cream, gel, essence and other preparation forms. The cosmetics are prepared by compounding of the nutritional preparation, penetrating agents and auxiliary materials. The penetrating agents are plant essential oils, azone, carbitol and other medical penetrating agents. The auxiliary materials are thickeners, emulsifiers, packet agents, wetting agents, emollients, flavoring agents, preservatives and solvents which are used as main medicinal raw materials. A large number of clinical trials prove that the medicinal cosmetics prepared form the nutritional preparation have good selective whitening spot-removing and nutritional efficacy for the skin of human body.

Description

technical field [0001] The invention belongs to the cross field of traditional Chinese medicine technology, bioengineering technology and chemical synthesis technology. It relates to the preparation of a compound formulation with selective whitening and freckle-removing effects, and the application of the formulation in cosmetics. Background technique [0002] Cosmetics with low stimulation efficacy have always been a hot spot pursued by society. However, the current functional cosmetics in the society cannot always meet everyone's requirements. Starting from the theory of traditional Chinese medicine, the company looks for effective prescriptions to ensure that its products have clear efficacy; using modern chemical positioning synthesis technology, the key raw materials in the prescriptions are synthesized according to the designed route. The key raw materials in the formula all come from oligopeptides (dipeptide to decapeptide) in genetic engineering, so as to ensure th...

Claims

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Application Information

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IPC IPC(8): A61K8/64A61K8/362A61K8/49A61K8/44A61K8/365A61K8/36A61Q19/02A61Q19/00
Inventor 李想张卫红鲁朝纲史钰
Owner SHAANXI HUIKANG BIO TECH CO LTD
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