The invention discloses a
phenanthridine-6-
formaldehyde derivative and a preparation method and application thereof.The preparation method comprises the steps that 2, 4, 5, 6-
tetra (9-carbazolyl)-isophthalonitrile serves as a photocatalyst, 1-azabicyclo [2.2. 2]
octane serves as a
hydrogen atom transfer catalyst, a
biphenyl isocyanide compound, the photocatalyst, the
hydrogen atom transfer catalyst and an alkali additive are jointly dissolved in 1, 3-
dioxolane, the mixture is stirred to be uniform, and the
phenanthridine-6-
formaldehyde derivative is obtained. And carrying out free radical tandem cyclization and acid-catalyzed
hydrolysis reaction to obtain the
phenanthridine-6-
formaldehyde derivative. The invention also provides a specific reaction equation. According to the developed synthesis method of the phenanthridine-6-formaldehyde derivative, the compound can be efficiently and conveniently prepared, the technical bottlenecks of harsh
reaction conditions and tedious steps in a traditional process are successfully overcome, raw materials which are low in price and easy to obtain are adopted, operation is carried out under mild conditions, the synthesis method has the outstanding advantages of being high in yield, safe and simple to operate,
environmentally friendly and the like, and the method is suitable for industrial production. Good industrial application potential is shown.