42 results about "Selective reaction" patented technology

The invention discloses a construction method and application of an SERS (Surface Enhanced Raman Scattering) sensor for detecting Mn < 7 + >. Belongs to the field of detection application, and the construction method of the SERS sensor for detecting Mn < 7 + > comprises the following steps: uniformly mixing an ABTS solution, a to-be-detected solution containing Mn < 7 + > and a silver nanoparticle solution, adding an acid solution to adjust the pH value of a reaction system, and reacting for 1-3 minutes. The SERS sensor for detecting Mn < 7 + > is applied to detection of heavy metal Mn < 7 + >. According to the method disclosed by the invention, by virtue of specific selection of the ABTS on Mn < 7 + > and addition of silver which has extremely high characteristics on SERS detection, convenient and rapid trace detection on Mn < 7 + > is realized. The selective reaction material explored by the invention is used for trace detection of heavy metal Mn < 7 + > by utilizing an SERS technology, and has important significance in application to actual life.

The present invention discloses a method for simultaneously reducing the biological inhibition of antibiotics and thiocyanate in erythromycin wastewater, and relates to the technical field of industrial wastewater treatment. The specific treatment method includes: by regulating the water quality characteristics of the wastewater, adding a selective reaction reagent, and regulating the reaction temperature, time, and stirring rate, the simultaneous microbial toxicity reduction of antibiotics and thiocyanate in the erythromycin wastewater is achieved. The method of the present invention has a stable reaction process, easy-to-regulate process conditions, a short time consumption, a strong selectivity in the removal process, and no need to regulate or remove other substances in the wastewater; it effectively solves the problem that erythromycin wastewater has a strong inhibitory effect on anaerobic biological processes due to the presence of high concentrations of erythromycin residual titers and thiocyanate ions, making it difficult to enter the anaerobic biological treatment process for efficient organic matter removal, and has good industrial application prospects.

The invention discloses a method for synchronously reducing biological inhibition of antibiotics and thiocyanate radicals in erythromycin wastewater, and relates to the technical field of industrial wastewater treatment. The specific treatment method comprises the following steps: regulating and controlling the water quality characteristics of the wastewater, adding a selective reaction reagent, and regulating and controlling the reaction temperature, time and stirring rate to realize synchronous microbial toxicity reduction of antibiotics and thiocyanate radicals in the erythromycin wastewater. According to the method, the reaction process is stable, the process conditions are easy to regulate and control, the consumed time is short, the selectivity of the removal process is high, and other substances in the wastewater do not need to be regulated and controlled or removed; the problems that high-concentration erythromycin residual titer and thiocyanate ions exist in the erythromycin wastewater, so that the inhibition performance on the anaerobic biological process is high, and the erythromycin wastewater is difficult to enter an anaerobic biological treatment process for efficient organic matter removal are effectively solved, and the erythromycin wastewater has a very good industrial application prospect.

The invention provides a parameter determination method for improving the efficiency of methyl oleate epoxidation reaction, which belongs to the technical field of methyl oleate epoxidation reaction, and comprises: collecting multiple groups of small-scale test data of methyl oleate epoxidation reaction; analyzing the small-scale test data by using a Bayesian optimization algorithm to obtain the correlation coefficient between each reaction condition parameter and the reaction efficiency data, and clustering according to the correlation coefficient to obtain key parameters, secondary parameters and micro-influence parameters; establishing a training data set, and training to obtain a two-way model of methyl oleate epoxidation reaction; discretizing a preset reaction efficiency requirement range, and inputting it into the model to obtain a reaction condition parameter set; using a genetic algorithm to use a to-be-selected reaction condition parameter set as an initial population, and iteratively optimizing to obtain target reaction condition parameters that meet the requirements; screening out a seed reaction condition parameter set; designing an orthogonal experiment to obtain an experimental data set, and selecting the reaction efficiency that is most similar to the preset target as the optimal reaction condition parameter.

The application provides a metal nanomaterial toxicity prediction method and device, the method comprises the following steps: collecting related data affecting the toxicity of the metal nanomaterial, wherein the related data comprises the physical and chemical properties of the metal nanomaterial, the interaction mode between the metal nanomaterial and organisms, the influence data of external environmental factors on the metal nanomaterial, and the selective reaction data of the metal nanomaterial between different organisms; screening target indexes from the related data and calculating the weights of the target indexes; inputting the target indexes and the weights corresponding to each target index into a pre-trained toxicity prediction model to obtain a metal nanomaterial toxicity prediction result. It can be seen that the application considers multiple dimensions and calculates the weights of the indexes, the indexes considered are more comprehensive, and the index weights can better reflect the influence degree of each index on the toxicity of the metal nanomaterial, thereby improving the accuracy of the model toxicity prediction.

The invention relates to the technical field of synthesis of sugar derivatives, in particular to a preparation method of sialic acid galactose disaccharide. The arylboronic acid is used for temporarily protecting hydroxyl groups at positions 4 and 6 of galactose, and after a sialic acid donor and a catalyst are added, sialic acid can be selectively coupled to hydroxyl groups at positions 3. The method can realize 3-site hydroxyl selective reaction under the condition that four hydroxyl groups at 2, 3, 4 and 6 sites of galactose are exposed at the same time, and has good reaction regioselectivity. The steps of selectively feeding and removing protective groups on 2, 4 and 6 sites are reduced, the synthetic route of sialic acid galactose disaccharide is simplified, and the synthetic yield is further improved. In addition, the sialylation reaction of the method provided by the invention has complete alpha selectivity, alpha and beta isomers do not need to be separated, and separation and purification are further simplified.

The invention discloses a method for producing carbonyl iron powder and a rare earth enriched material by treating rare earth iron slag through a carbonylation method, and belongs to the technical field of metal waste recovery. Comprising the steps of pretreatment, drying, rare earth catalytic self-activation, fluidization reduction and carbonyl method selective iron separation. A metastable-state oxygen vacancy structure is constructed by means of rare earth catalytic self-activation, an efficient electron transfer channel is provided for deep reduction and carbonylation separation of iron, molecular-level dissociation of iron and rare earth is achieved in cooperation with a selective reaction of a carbonyl method, iron is converted into high-value carbonyl iron powder, meanwhile, the enrichment degree of rare earth elements is greatly increased, and the preparation method is suitable for industrial production. Original industrial solid waste is converted into a product with economic value and application potential, and the comprehensive utilization rate of resources is remarkably increased.

The invention discloses a two-dimensional semiconductor in-plane integration method and device, and the method comprises the steps: providing a first two-dimensional single-layer material, and placing the first two-dimensional single-layer material on a target substrate; partially stacking the second two-dimensional single-layer material on the first two-dimensional single-layer material to form a Van der Waals heterojunction comprising a stacking region and a single-layer region; an excitation light source of which the photon energy is greater than the luminous band gap of the first two-dimensional single-layer material and / or the second two-dimensional single-layer material is utilized, so that the van der Waals heterojunction is subjected to selective photochemical reaction, and the second two-dimensional single-layer material in the stacking region is removed through selective reaction; and the first two-dimensional single-layer material and the second two-dimensional single-layer material are integrated and spliced in the same plane. According to the two-dimensional semiconductor in-plane integration method and the two-dimensional semiconductor in-plane integration device provided by the invention, the upper-layer material in the stacking region is selectively removed by utilizing the electronic state distribution difference of different two-dimensional materials in the stacking region and the single-layer region in combination with the photochemical reaction, so that the in-plane splicing of the two-dimensional materials is realized.

The invention relates to the technical field of organic synthesis and biochemical engineering, and discloses a preparation method of 3-o-ethyl ascorbic acid, which comprises the following steps: (1) carrying out pre-acetylation reaction on ascorbic acid and vinyl acetate under the catalysis of lipase to obtain 6-acetyl ascorbic acid; (2) carrying out ethylation reaction on the product in the step (1) and diethyl carbonate by taking ionic liquid as a catalyst; (3) purifying the product by combining supercritical COextraction with membrane filtration; according to the preparation method of the 3-o-ethyl ascorbic acid provided by the invention, the purity and the yield of the product are remarkably improved through a synergistic process of lipase pre-acetylation, ionic liquid catalytic ethylation and supercritical COextraction combined with membrane filtration and purification; 6-hydroxyl of ascorbic acid can be selectively protected. The step utilizes the specific catalysis function of the enzyme to avoid the non-selective reaction of other hydroxyl groups.

The invention relates to the technical field of medicine synthesis, and particularly discloses a preparation method of a cefdil intermediate. According to the invention, trichloroisocyanuric acid (TCCA) is taken as a green chlorination reagent, and reaction solvent and temperature are selected, so that the problem that benzene ring polychlorination side reaction and aldehyde functional group nucleophilic substitution side reaction are effectively inhibited while ortho-position high-selectivity mono-chlorination of phenolic hydroxyl is realized is successfully solved; and thus, the 2-chloro-3-hydroxy-4-methoxybenzaldehyde can be obtained at a high yield. On the basis, according to the scheme, subsequent anhydridation and amidation steps are further optimized, trimethylacetyl chloride is adopted to replace a traditional highly toxic activating reagent, safety and atom economy are improved, and meanwhile continuity and high efficiency of the reaction are ensured. The whole process route is reasonable in design, simple and convenient to operate and high in safety, raw materials and reagents are easy to obtain, the total yield of the reaction and the purity of the product are remarkably improved, and the method shows a wide application prospect in large-scale industrial production of the ceftidil.

The invention provides a preparation method of deuterated chloroform (CCl3D). The method comprises the following steps: under the action of ultraviolet-visible light and a catalyst, mixing deuterated methane and Cl2 in a photochemical reactor, and sequentially carrying out alkali washing, liquid separation, drying and distillation treatment to obtain deuterated chloroform. According to the method, a novel efficient catalyst is adopted and matched with a photochemical reactor, and selective reaction of deuterated methane and chlorine under mild conditions is achieved. According to the method, raw materials for producing deuterated chloroform are easy to obtain, the preparation period is short, continuous production can be achieved, in addition, by-products such as deuterated monochloromethane and deuterated dichloromethane with certain application value are further produced in the method, and the economic benefits of the whole production process are further improved. In practical application, the deuterated chloroform prepared by the invention not only can improve the analysis accuracy, enhance the repeatability and comparability of experiments and protect experimental equipment and samples, but also can meet specific application requirements and improve the product quality.

The invention discloses an efficient carbon-carbon bond construction and synthesis method based on transition metal catalysis, and relates to the technical field of organic chemistry, and the efficient carbon-carbon bond construction and synthesis method comprises the steps of catalyst preparation and selection, reaction system construction, reaction condition optimization, product separation and catalyst recovery. Traditional expensive metals such as palladium and the like are replaced, a metal organic framework material UiO-66-NH2 and a covalent organic framework material COF-366 are adopted as carriers, metal active sites are accurately dispersed by utilizing the high specific surface area and an adjustable and controllable pore channel structure of the carriers, the metal consumption is reduced, metal atomic-scale accurate loading is realized by combining an atomic layer deposition technology, the catalyst cost is reduced, and meanwhile, the preparation method is simple and easy to implement. The activity and selectivity of the catalyst obtained through high-throughput screening and machine learning optimization are remarkably improved, and efficient proceeding of a carbon-carbon bond construction reaction can be effectively promoted.

There is disclosed a highly stable biocatalytic multi-enzyme system on hydrophobic support for the efficient and continuous hydrogenation of carbon dioxide (CO2) to formate. The system immobilizes formate dehydrogenase (FDH), glucose dehydrogenase (GDH), and carbonic anhydrase (CA) enzymes on a hydrophobic surface-modified metal-organic framework (MOF), SA-HKUST-1. The hydrophobic surface modification with stearic acid enhances the enzyme stability and reusability, maintaining 95% activity after four cycles. The hydrophobicity of SA-HKUST-1 improves CO2 diffusion to the immobilized enzymes, significantly boosting the formate production. Enzyme specificity ensures selective reactions, with FDH facilitating CO2 bioconversion, CA accelerating CO2 hydration and GDH facilitating cofactor regeneration within the system. The system demonstrates superior performance, producing 255.8 mM formate per gram of MOF per hour. Operating under mild conditions with simple equipment, it reduces costs and eliminates harmful by-products. This invention offers an eco-friendly, sustainable approach for CO2 mitigation, with potential applications in industrial CO2 conversion processes.

The present disclosure relates to a method for controlling multi electrons spin selective reactions, a coating and an electrode. The attachment between the chiral coating surface layer and the electrode is configured for causing charge rearrangement, spin polarization of the electrode surface, controllably affecting coherent and entangled properties of the multi-electrons being injected from or to the electrode surface thereby modifying the rate of the multi electrons spin selective reactions and product selectivity.

This invention relates to the field of lipid biocatalysis and functional lipid preparation technology, specifically to a COF immobilized lipase system for the directed synthesis of sn-1,3-diacylglycerol, its preparation method, and its applications. This invention provides a method and system for regulating the glycerol hydrolysis reaction pathway of lipases using a cooperative covalent organic framework. By introducing multiple functionally complementary and irreplaceable covalent organic framework modules in the same reaction process, it preferentially promotes the conversion of triglycerides to sn-1,3DAG; significantly inhibits the acyl migration of sn-1,3DAG to sn-1,2DAG; reduces secondary non-selective reactions of DAG; and improves the proportion and compositional stability of sn-1,3DAG at the reaction pathway level.

This invention discloses a substrate interface pretreatment method for anisotropic magnetoresistive thin film deposition, belonging to the field of pre-deposition processing technology for thin film deposition. The method includes: (1) wiping the substrate surface with dilute hydrofluoric acid; (2) placing the substrate into a deposition chamber and evacuating it to a vacuum level ≤1×10⁻⁶. ‑6 Torr; (3) Introduce a protective atmosphere and perform a stepwise heating treatment on the substrate, including at least three steps: 100 ℃, 300 ℃, and 500 ℃. Hold each step for 20 min to 30 min to allow hydrofluoric acid to remove the oxide layer in situ and activate the surface; (4) Cool down to room temperature, stop the gas supply, and evacuate. This invention uses a synergistic process of wiping with dilute hydrofluoric acid and stepwise heating in the chamber to sequentially complete the removal of physically adsorbed water, selective reaction of the oxide layer, and activation of surface polarization bonds. The average thickness of the remaining oxide layer is ≤5 nm, and the density of surface active polarization bonds is increased by more than 10 times. The entire process is carried out in situ to avoid secondary contamination and significantly enhances the adhesion and crystal quality of the subsequently deposited film.

An microreactor array is provided that includes a plurality of microreactors in a substrate. The plurality of microreactors is in fluid communication with a common fluid delivery channel. Each of the microreactors includes an electrode configured to generate one or more gaseous bubbles that can block reagent access to selected microreactors. A method for selective reactions in a microreactor array is also provide.

This invention discloses a method for treating rare earth iron slag using carbonylation to produce carbonyl iron powder and rare earth enriched materials, belonging to the field of metal waste recycling technology. The method includes pretreatment, drying, rare earth catalytic self-activation, fluidized bed reduction, and selective separation of iron via carbonylation. This invention utilizes rare earth catalytic self-activation to construct a metastable oxygen vacancy structure, providing an efficient electron transfer channel for the deep reduction and carbonylation separation of iron. Combined with the selective reaction of the carbonylation method, it achieves molecular-level dissociation of iron and rare earth elements, converting iron into high-value carbonyl iron powder while significantly increasing the enrichment of rare earth elements. This transforms industrial solid waste into a product with both economic value and application potential, significantly improving the comprehensive utilization rate of resources.

To provide a generation device capable of virtually producing a polymer product which is a product of a polymer reaction.SOLUTION: A generation device comprises: means I for setting a polymer compound A; means II for acquiring a candidate list of reaction types applicable to a reaction point of the set polymer compound A; means III for selecting from the acquired candidate list and setting the reaction type; means IV for acquiring a candidate compound group of low or medium molecular weight compounds; means V for selecting from the acquired candidate compound group and setting a low or medium molecular weight compound B; means VI for virtually subjecting the set polymer compound A and the set low or medium molecular weight compound B to the set reaction type to virtually generate a polymer product C.SELECTED DRAWING: None

Disclosed are methods which comprise the preparation of beta-lactones which provide for shorter reaction times with lower by-product formation. The method comprises contacting carbon monoxide with an epoxide in the presence of a carbonylation catalyst to form a reaction mixture under conditions such that the carbon monoxide distributed throughout the reaction mixture and the reaction mixture is substantially saturated with carbon monoxide. The reaction conditions and reactor designs are chosen to distribute the carbon monoxide throughout the reaction mixture and to maintain the reaction mixture as substantially saturated with carbon monoxide. Under these conditions the formation of beta-lactones over the formation of by-products is favored.

The invention discloses a blowing method for replacing Ar with CO2 for stainless steel smelting in an AOD (argon oxygen decarburization) furnace, which belongs to the technical field of ferrous metallurgy and specifically comprises the step of blowing CO2 in proportion at the initial stage, the middle stage and the end stage of decarburization, so that the CO2 accounts for 20-100% of the total blowing amount. By controlling the furnace temperature to be 1600-1750 DEG C, the FeO content in the slag to be less than or equal to 0.5%, the CO / CO2 ratio to be 2-6 and the slag system alkalinity to be 1.7-2.2, the selective reaction of CO2 and carbon is realized, so that the effects of Ar dilution, stirring and chromium protection are replaced. According to the method, argon consumption can be effectively reduced by 30%-100%, the chromium loss is kept to be smaller than or equal to 0.2%, the decarburization efficiency is improved, terminal temperature control is improved, the process stability is high, the cost advantage is remarkable, and the method is suitable for AOD smelting production of various kinds of stainless steel.

The invention provides a coupling treatment system and method for resource utilization of carbon and sulfur elements in industrial wastewater, and relates to the technical field of water treatment. The coupling treatment system provided by the invention comprises an adjusting tank, a COD (Chemical Oxygen Demand) recycling biological selection reactor, a first SO4 < 2-> recycling biological selection reactor and a second SO4 < 2-> recycling biological selection reactor. The MPB and the SRB are organically combined in the same reactor (namely a COD resource biological selection reactor), the problem of microbial metabolism conflict caused by coexistence of C / S elements in sewage can be solved by adopting a single-phase reactor, and compared with a two-phase reactor, the interspecific mass transfer efficiency is greatly improved, and the reaction rate and the resource utilization rate are improved; meanwhile, a sulfur directional oxidation reactor (namely a first SO4 < 2-> recycling biological selection reactor) and a sulfur refining module (namely a second SO4 < 2-> recycling biological selection reactor) are additionally arranged on the basis of a single-phase reactor, so that closed-loop recovery of sulfur elements is realized.

The invention discloses a method for synthesizing diaminopyrimidine nitrogen oxide, which comprises: performing a ring-closing reaction on ethoxymethylene cyanoacetoethyl ester and guanidine in a reaction solvent to obtain a pyrimidine skeleton intermediate, performing a decarboxylation reaction in a decarboxylation reagent and an organic solvent to obtain a diaminopyrimidine intermediate, and reacting with an oxidant to obtain diaminopyrimidine nitrogen oxide. The invention uses ethoxymethylene cyanoacetoethyl ester and guanidine as raw materials, sequentially undergoes a ring-closing reaction, a hydrolysis decarboxylation reaction and an oxidation reaction to obtain diaminopyrimidine nitrogen oxide in high yield. The synthetic route is novel, and a new synthetic method is provided for 2,4-diaminopyrimidine and 2,4-diaminopyrimidine nitrogen oxide. The raw materials are cheap and easy to obtain, the cost is low, and operations such as pressurization are not required, and a synthetic route with simple operation, short steps, high reaction selectivity and good safety is provided.

The application provides a preparation method of deuterated chloroform (CCl3D). The method comprises the following steps: after deuterated methane and Cl2 are mixed in a photochemical reactor under the action of ultraviolet-visible light and a catalyst, deuterated chloroform is obtained through the treatment of alkali washing, liquid separation, drying and distillation in sequence. The method realizes the selective reaction of deuterated methane and chlorine under mild conditions by using a new type of high-efficiency catalyst and cooperating with a photochemical reactor. The raw material for producing the deuterated chloroform is easy to obtain, the preparation period is short, and the continuous production can be realized. In addition, the method also produces by-products such as deuterated monochloromethane and deuterated dichloromethane, which have certain application value, and further improves the economic benefits of the overall production process. The deuterated chloroform prepared by the application can not only improve the accuracy of analysis, enhance the repeatability and comparability of experiments, protect experimental equipment and samples, but also meet specific application requirements and improve product quality in practical application.

The invention discloses a preparation method and application of a boric acid ester modified graphdiyne oxide wrapped gold nanosphere composite material. The preparation method comprises the steps of preparation of a thin graphdiyne oxide sheet, preparation of a graphdiyne oxide wrapped gold nanosphere composite material and preparation of the boric acid ester modified graphdiyne oxide wrapped gold nanosphere composite material. According to the invention, 4-aminophenylboronic acid pinacol ester is modified on a prepared graphdiyne oxide coated gold nanosphere composite material by utilizing a coupling reaction of carboxyl and amino, and an SERS detection material for H2O2 in living cells is constructed, so that high-sensitivity and high-specificity detection of H2O2 is realized. The material constructed by the invention has good biocompatibility and unique boric acid-phenol switch, has selective reaction on H2O2, can be used for specific detection of H2O2 in living cells, and can effectively overcome the problem of non-reproducibility of SERS (Surface Enhanced Raman Scattering) signals caused by non-uniform adsorption and irregular distribution of substrate molecules as an internal standard signal.

The application discloses a method for forming a wafer pad with controllable recess degree and a structure, and relates to the field of semiconductor manufacturing. The method comprises the following steps: S100, forming a barrier layer, a seed layer and first and second pillars for bonding on a wafer; S200, depositing a stop layer on the top of the first pillar, the thickness of the stop layer being equal to a target recess degree, and the total height of the stop layer and the first pillar being smaller than the height of the second pillar; S300, performing a planarization treatment on the second pillar, and judging a process endpoint by using the polishing rate difference between the stop layer and the second pillar; and S400, removing the stop layer by etching with a selective reaction gas to expose the top of the first pillar. The application pre-sets the recess space by the stop layer, effectively protects the first pillar in the planarization process, avoids the risk of excessive polishing or insufficient polishing, and realizes clear process endpoint judgment by using the polishing selectivity ratio between materials, so that the recess degree control precision, process uniformity and bonding reliability are significantly improved.

A buoyant permeable reactive barrier for blocking the emission of greenhouse gasses (e.g., methane) and volatile compounds (e.g., ammonia, sulfur) from a body of water is provided. The buoyant reactive barrier includes a plurality of buoyant reactive barrier elements arranged in one or more substantially planar layers on the surface of the water. The reactive barrier elements are selected to provide for selective permeability of certain compounds / gasses through the buoyant barrier, while blocking or reacting with other compounds / gasses. At least a subset of the barrier elements may be provided with a catalyst for catalyzing the oxidation of volatile compounds to less volatile products. At least a subset of the barrier elements may be sufficiently large to impart wind and wave resistance to the reactive barrier. The buoyant barrier may include a gelatinous extracellular polymeric matrix that fills the interstitial spaces between the plurality of buoyant reactive barrier elements.

A microreactor array is provided that includes a plurality of microreactors in a substrate. The plurality of microreactors is in fluid communication with a common fluid delivery channel. Each of the microreactors includes an electrode configured to generate one or more gaseous bubbles that can block reagent access to selected microreactors. A method for selective reactions in a microreactor array is also provided. The method includes flooding the array of microreactors with a first fluid selected to release a gas during electrolysis, applying a bias to the electrode associated with one or more selected microreactors in the array, thereby forming one or more gaseous bubbles at or near the electrode. The next step involves flushing the array with a second fluid, and carrying out a reaction in the microreactors that are not blocked by the bubble.

The invention discloses an in-situ micro-area beryl Rb-Sr dating correction method which comprises the following steps: 1, after a selective reaction active gas reacts with Sr, calculating an 86Sr signal by using a signal of a product, so as to improve the accuracy of a Sr element signal; 2, correcting the ratio of 87Rb / 87Sr and the ratio of 86Sr / 87Sr by adopting a glass standard substance with a uniform Rb / Sr isotope ratio; the method comprises the following steps of: drawing an inverse isochrone graph by adopting a substrate-matched beryl standard substance HJLG241 or XXG251, calculating an apparent age, calculating a substrate effect deviation coefficient according to the apparent age and a recommended age, and applying the coefficient to 86Sr / 87Sr ratio correction of an unknown sample. According to the method, accurate dating of the in-situ micro-area beryl Rb-Sr is realized, accurate dating of the laser micro-area beryl Rb-Sr is realized, and the method has the advantages of high spatial resolution, high dating success rate, short test period and the like.

The invention relates to the technical field of synthesis of sugar derivatives, in particular to a preparation method of O-sugar amino acid. The arylboronic acid is used for temporarily protecting hydroxyls at positions 4 and 6 of galactosamine of sugar amino acid, sugar is coupled to a hydroxyl at a position 3 after a sugar donor and a catalyst are added, and then the arylboronic acid can be removed through simple post-treatment. According to the method, the selective reaction of the 3-site hydroxyl can be realized under the condition that the 3-site hydroxyl, the 4-site hydroxyl and the 6-site hydroxyl of galactosamine are exposed at the same time, so that the method has good reaction regioselectivity, the steps of selectively feeding and removing protective groups at the 4-site and the 6-site are reduced, the synthesis path of O-sugar amino acid is simplified, and the synthesis yield is further improved. In addition, the method provided by the invention is simple to operate, mild in condition and high in product yield, and can be popularized to industrial production.