26 results about "Mirabilis jalapa" patented technology

The invention relates to a composition with antioxidant and brightening effects and capable of delaying skin saccharification as well as a preparation method and application of the composition, and belongs to the field of cosmetics. The composition comprises an ormosia henryi bark extract, tetrahydrocurcumin, a mirabilis jalapa extracting solution, a surfactant, polyol, phospholipid and a solvent. The composition provided by the invention has good illumination stability and high-temperature stability, and the composition provided by the invention is high in bioavailability, and has good antioxidant and brightening effects and lipofuscin and RAGE level inhibition effects.

The invention relates to a traditional Chinese medicine composition for treating or preventing osteoporosis, and discloses application of the traditional Chinese medicine composition in preparation of a medicine for treating and / or preventing osteoporosis. The traditional Chinese medicine composition is prepared from the following traditional Chinese medicinal materials in parts by weight: 22-26 parts of bull penis, 8-12 parts of cinnamon, 10-14 parts of alfalfa seeds, 8-12 parts of galangal, 10-14 parts of onion seeds, 8-12 parts of clove, 10-14 parts of fructus ulmi, 8-12 parts of pepper, 12-16 parts of carrot seeds, 38-46 parts of sesame, 10-14 parts of muskmelon seeds, 56-64 parts of almonds, 10-14 parts of cucumber seeds, 8-12 parts of asarum, 10-14 parts of semen allii tuberosi and 16-20 parts of limonium macrophyllum. The medicine is prepared from the following raw materials in parts by weight: 10-14 parts of dill seeds, 13-17 parts of tribulus terrestris, 36-44 parts of milk peaches, 8-12 parts of mirabilis jalapa roots, 18-22 parts of cotton seeds, 10-14 parts of radix aucklandiae, 10-14 parts of ginger slices, 8-12 parts of nutmeg coats, 46-54 parts of pinus bungeana, 10-14 parts of sesame seeds, 3-7 parts of saffron, 8-12 parts of fern, 8-12 parts of fructus piperis longi and 18-22 parts of nutmeg.

The invention relates to the field of plant extraction, and particularly discloses a preparation method of a millettia indica extract, the millettia indica extract obtained by the preparation method comprises the steps of pretreatment, extraction, purification and the like contains millettia indica amide with higher purity, and in the extraction step, the millettia indica amide is added into the millettia indica extract to obtain the millettia indica extract. According to the method, the eutecticevaporate solvent is used for extracting the millettia in a low-temperature environment under the assistance of ultrasonic waves, so that the heat-sensitive millettia amide in the extract is effectively protected; and through the special eutectic solvent, the mirabilis jalapa amide can be better dissolved out, and on the basis, the mirabilis jalapa amide with relatively high purity can be obtained in the mirabilis jalapa extract through simple re-dissolution of an organic solvent.

The invention discloses a composition containing dendrobium officinale and capable of promoting synthesis of type I collagen, and belongs to the field of dressing preparations. The composition comprises the following raw materials: a dendrobium officinale extract, an emblic leafflower fruit extract, a mirabilis jalapa extract and ascorbic acid polypeptide, and the raw materials are synergistically compounded, so that the composition provided by the invention has a remarkable effect of promoting synthesis of type I collagen.

The invention relates to the field of natural medicinal chemistry, in particular to application of mirabilis himalaica to preparation of a product with whitening and anti-oxidation effects, and innovatively adopts mirabilis himalaica to research the whitening and anti-oxidation effects. The mirabilis himalaica-derived extracellular vesicle-like nanoparticles are found to be capable of reducing the content of melanin in melanoma cells at the cellular level and inhibiting the activity of tyrosinase. In addition, the mirabilis himalaica source extracellular vesicle-like nanoparticles can also scavenge free radical ions, inhibit the generation of active oxygen in cells and promote the improvement of cell viability. The mirabilis himalaica-derived extracellular vesicle-like nanoparticles disclosed by the invention can be sufficiently internalized and absorbed by melanoma cells, the melanin content in the melanoma cells is remarkably reduced, melanin pigmentation on the epidermis of a mouse is remarkably reduced, and the mirabilis himalaica-derived extracellular vesicle-like nanoparticles also have excellent oxidation resistance. The method has potential for preparing products with whitening and antioxidant effects.

The invention belongs to the technical field of cosmetics, and particularly relates to a soothing and repairing composition and application thereof. The soothing and repairing composition provided by the invention is prepared from the stephania tetrandra extract, the phoenix dactylifera fruit extract, the flower extract and the mirabilis jalapa extract through specific compatibility, and all the components generate a synergistic effect, so that the transdermal absorption of active ingredients can be remarkably enhanced; experimental data show that the composition can effectively improve the hyaluronidase inhibition rate and the TNF-alpha inhibition rate, and has excellent soothing and repairing effects; the preparation method of the composition is simple and convenient to operate and easy to realize industrial large-scale production, and has a good industrial application prospect; when the composition is applied to the essence, the TEWL value improvement rate and the a * value improvement rate of the essence can be remarkably improved, and the soothing and repairing effects are obvious; and human body patch test results of the essence show that the essence is mild and non-irritating, so that the composition disclosed by the invention has wide market application value in skin care products.

The invention provides a preparation method and application of a mirabilis jalapa extract, and belongs to the technical field of skin care products. The method comprises the following steps: (1) crushing mirabilis jalapa until the particle size is 100-300 microns, and then carrying out steam explosion treatment to obtain steam-exploded mirabilis jalapa; (2) mixing the steam-exploded mirabilis jalapa with water, adding a compound enzyme preparation, and performing enzymolysis treatment to obtain enzymatic hydrolysate; and (3) carrying out concentration and freeze-drying treatment on the enzymatic hydrolysate to obtain the mirabilis jalapa extract. According to the method, the mirabilis jalapa is subjected to steam explosion treatment and then subjected to enzymolysis treatment through mannase, cellulase and xylanase, so that effective components in the mirabilis jalapa can be fully extracted into enzymatic hydrolysate, and the extraction efficiency is guaranteed.

The invention provides synergistic soothing and repairing freeze-dried powder which is prepared from the following raw materials in percentage by weight: 0.1 to 2 percent of edelweiss cell extract, 0.5 to 3 percent of mirabilis jalapa extract, 0.1 to 2 percent of crithmum maritimum callus culture filtrate, 0.01 to 0.1 percent of palmitoyl tripeptide-8 and 0.01 to 0.1 percent of heptapeptide-6. The edelweiss cell extract, the mirabilis jalapa extract and the crithmum maritimum callus culture filtrate are innovatively introduced, a synergistic system is formed by the edelweiss cell extract, the mirabilis jalapa extract, the crithmum maritimum callus culture filtrate, palmitoyl tripeptide-8, heptapeptide-6, tremella polysaccharide and the like, a low-temperature gradient freeze-drying process is combined, and the effects of deep anti-inflammation, efficient barrier repair and rapid and lasting relieving are achieved.

The invention relates to the technical field of soothing and repairing cosmetics, in particular to a soothing and repairing mirabilis jalapa liposome composition, a mask liquid and a preparation method and application of the soothing and repairing mirabilis jalapa liposome composition and the mask liquid. The composition comprises a saussurea involucrata liposome, a triple ceramide liposome and a dihydroavena alkaloid liposome, wherein the weight ratio of the saussurea involucrata liposome to the triple ceramide liposome to the dihydroavena alkaloid liposome is (1-8): (1-5): (1-7); the particle size of the mirabilis jalapa liposome is 50 to 150 nm; the particle size of the triple ceramide liposome is 100 to 200 nm; the particle size of the dihydrooat alkaloid liposome is 100 to 200 nm. According to the invention, specific active components are selected and compounded in a liposome form, so that a synergistic regulation effect can be realized, the expression of a TRPV1 receptor and inflammatory factors is remarkably inhibited, and a good soothing and repairing effect is further realized.

The invention belongs to the field of cosmetics and relates to an anti-wrinkle and skin-firming composition and its application in cosmetics. The anti-wrinkle and skin-firming composition uses dipeptide diaminobutyryl benzylamide diacetate, acetylated sodium hyaluronate, Mirabilis jalapa extract and Glycine soja protein as main active ingredients, and achieves multiple effects of moisturizing, improving skin elasticity and anti-wrinkle under a reasonable mass ratio of (2-3): (5-7): 1: (8-10).

The invention belongs to the field of Tibetan medicines, and particularly relates to a Tibetan medicine composition for tonifying yang and a preparation method thereof. The Tibetan medicine composition for tonifying yang is prepared from the following raw materials in parts by weight: 120 to 130 parts of pomegranate, 30 to 40 parts of cortex cinnamomi, 15 to 25 parts of fructus amomi rotundus, 10 to 20 parts of fructus piperis longi, 45 to 55 parts of saffron crocus, 35 to 45 parts of chingma abutilon seed, 45 to 55 parts of radix asparagi, 70 to 80 parts of radix angelicae sinensis, 45 to 55 parts of mirabilis himalaica, 70 to 80 parts of fructus tribuli, 70 to 80 parts of snow lotus herb and 70 to 80 parts of five-root concentrated paste. The composition is scientific in formula, standard in preparation, high in safety and free of obvious side effects, sexual dysfunction and accompanying discomfort caused by kidney-yang deficiency can be improved in a targeted mode, and the clinical application effect is remarkable.

A new Petchoa plant particularly distinguished by having large red-purple flowers and a semi-upright habit, is disclosed.

The application discloses a traditional Chinese medicine composition for inhibiting hyaluronidase activity and a hyaluronidase inhibitor. The traditional Chinese medicine composition for inhibiting hyaluronidase activity comprises 1-12 parts of Mirabilis jalapa, 1-12 parts of Cnidium monnieri and 1-6 parts of Coptis chinensis by weight. The hyaluronidase inhibitor comprises 1-2 parts of Tween, 2-5 parts of lecithin, 0.1-0.5 parts of cholesterol, 40-80 parts of the traditional Chinese medicine composition and 80-100 parts of deionized water by weight. The traditional Chinese medicine composition and the hyaluronidase inhibitor can effectively inhibit the activity of hyaluronidase. The combination of Mirabilis jalapa, Cnidium monnieri and Coptis chinensis can effectively inhibit the activity of hyaluronidase. Mirabilis jalapa, Cnidium monnieri and Coptis chinensis have a remarkable synergistic effect on the activity of hyaluronidase.

The invention relates to the field of anti-wrinkle and firming skin care products, in particular to an anti-wrinkle and firming composition beneficial to collagen absorption and retention and skin filling. An anti-wrinkle firming composition helpful for collagen absorption and retention and filling skin comprises the following components in percentage by mass: 0.05-1% of collagen, 0.1-5% of a perilla frutescens extract, 0.1-5% of a mirabilis jalapa extract, 0.1-5% of a rodendranthus spicatus extract, 0.1-5% of a centella asiatica extract, 0.1-5% of a white truffle fungus extract and a solvent. According to the present invention, the collagen can be easily absorbed, retained and filled into the skin so as to further improve the anti-wrinkle and firming effects.

The invention belongs to the technical field of biological medicines and cosmetics, and particularly relates to a skin anti-aging substance composition with a mitochondrial enhancing effect, a preparation method, application and a product thereof. The composition consists of spermidine, quercetin, a mirabilis jalapa extract, vitamin K2, adenosine and a solvent. The composition provided by the invention can repair a mitochondrial ultrastructure, recover ATP generation and maintain mitochondrial membrane potential, and can also reduce accumulation of an aging marker SA-beta-gal, up-regulate type I collagen and enhance Sirt3 expression.

The invention relates to the field of Pickering emulsion, and particularly discloses mirabilis jalapa endosperm powder Pickering emulsion as well as a preparation method and application thereof. The mirabilis jalapa endosperm powder Pickering emulsion is prepared from the following raw materials in percentage by weight: 1 to 10 percent of mirabilis jalapa endosperm powder particles, 10 to 70 percent of grease and the balance of water. The mirabilis jalapa endosperm powder Pickering emulsion can be used in the field of cosmetics, and has the advantages of good heat resistance and cold resistance, excellent long-term stability, capability of emulsifying polar oil and non-polar oil at the same time, and no conflict with a thickening agent.

The invention relates to the technical field of analysis method detection, and provides a detection method of a pharmaceutical composition. The detection method of the pharmaceutical composition comprises the following steps: extracting components of the pharmaceutical composition comprising tribulus terrestris, rhizoma polygonati and mirabilis himalaica, and preparing the extracted components into a test solution; dissolving a reference substance to prepare a reference substance solution; and respectively injecting the reference solution and the test solution into a liquid chromatograph, and detecting according to preset chromatographic conditions. Wherein the reference substance is prepared from 5-hydroxymethylfurfural, quercetin-3-O-gentiobioside and isorhamnetin-3-O-gentiobioside, and the reference substance is prepared from 2-hydroxymethylfurfural, quercetin-3-O-gentiobioside The detection method of the pharmaceutical composition can be used for quantitative analysis of multi-components by single marker, the detection efficiency is improved, and the detection cost is reduced.

The present application relates to a kind of composition with anti-glycation inhibiting RAGE and lightening effect, its preparation method, preparation product and application, belong to medical instrument field, medical or dressing preparation field, biological medicine manufacturing technology field and preparation manufacturing technology field.The composition includes sapota bark extract, tetrahydrocurcumin, mirabilis jalapa extract, surfactant, polyol, phospholipid and solvent.The preparation method provided in the present application includes using 1,3-butanediol with 25%~35% 1,3-butanediol formula amount of 1,3-butanediol and surfactant, sapota bark extract, tetrahydrocurcumin are mixed and dissolved;And the remaining polyol and phospholipid are mixed and the like steps, improve the light stability and high temperature stability of the obtained composition, have unexpected technical effects, and simple operation, without high pressure mean equipment, equipment cost is low.In addition, the composition provided in the present application has high bioavailability, has good antioxidant lightening effect and inhibiting lipofuscin and RAGE level effect.

The invention relates to ointment for preventing and / or treating bacon type diabetes as well as a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicine and Tibetan medicine. The ointment for preventing and / or treating bacon type diabetes mellitus is prepared from the following components in parts by mass: 8 to 16 parts of rhizoma curcumae longae, 13 to 25 parts of cortex berberidis, 6 to 15 parts of fructus phyllanthi, 12 to 20 parts of fructus tribuli, 6 to 12 parts of mirabilis himalaica, 10 to 20 parts of fructus chebulae, 13 to 25 parts of herba thlaspi, 12 to 20 parts of hollyhock, 350 to 910 parts of vegetable oil and 5 to 15 parts of greasy matrix. The ointment disclosed by the invention can be used for preventing and / or treating bacon type diabetes mellitus, and has the characteristics of strong pertinence, high safety and stable and remarkable curative effect.

This application relates to a sublingual spray formulation containing the active ingredients of Basang Pill and its preparation method, belonging to the field of pharmaceutical technology. The sublingual spray formulation containing the active ingredients of Basang Pill provided by this application includes the active ingredients, which consist of Basang Pill extract and a Western-style sleep-aiding ingredient, with a weight ratio of (20~1):2. The Western-style sleep-aiding ingredient is selected from one or more of melatonin, γ-aminobutyric acid, and L-theanine. The Basang Pill extract is obtained from a traditional Chinese medicine composition including Terminalia chebula, Terminalia chebula, Phyllanthus emblica, Polygonatum sibiricum, Asparagus cochinchinensis, Celery scabra, Tribulus terrestris, and Mirabilis jalapa. This application achieves a synergistic effect by scientifically combining the Basang Pill extract with the Western-style sleep-aiding ingredient, realizing a new use for an old drug and providing a solution for insomnia patients with rapid onset and high bioavailability.

The invention relates to the technical field of preparation of health-care products, and provides a compound foot bath tablet as well as a preparation method and application thereof. The compound foot bath tablet comprises the following components: a monarch drug, a ministerial drug, an adjuvant drug, a conductant drug and auxiliary materials. Wherein the monarch drug comprises a rhodiola rosea extract, safflower, a lucid ganoderma extract, sea-buckthorn and crocus sativus salt; the ministerial drugs comprise fructus chebulae extract, fructus terminaliae billericae extract, emblic leafflower fruit extract, fructus schizandrae extract, radix codonopsis, radix salviae miltiorrhizae, herba leonuri, radix notoginseng, juniperus formosana, rhizoma kaempferiae extract, radix astragali seu hedysari, myricaria laxiflora, rhizoma chuanxiong, sea salt, herba artemisiae annuae, lavender and mirabilis jalapa extract; the adjuvant drugs comprise gentiana macrophylla extract, gentian extract, rhizoma bolbostemmae extract, divaricate saposhnikovia root, citrus peel, sappan wood, perilla leaf, herba lycopi extract, cowherb seed extract, tribulus terrestris, rhododendron and rheum palmatum; the conductant drug comprises gastrodia elata and calamus; the auxiliary materials comprise an effervescing agent, a disintegrating agent and an adhesive. The compound foot bath tablet can clear damp and help sleep, and is convenient to use, safe and reliable.

This invention, entitled "Anti-wrinkle Eye Serum, its Preparation Method, and Application," belongs to the field of cosmetic technology. The technical problem to be solved is anti-wrinkle treatment of the eyes and improvement of elasticity around the eyes. The key technical solution is an anti-wrinkle eye serum, comprising the following raw materials by weight percentage: 5-16% skin conditioning agent, 5-15% moisturizer, 3-8% emollient, 0.1-1% thickener, 0.1-1% preservative, and the balance being deionized water. The skin conditioning agent comprises a mixture of skin conditioning agent 1, skin conditioning agent 2, and skin conditioning agent 3 in a mass ratio of 4-10:0.5-3:0.5-3. Skin conditioning agent 3 is a mixture of Mirabilis jalapa extract, Butcher's broom root extract, Centella asiatica extract, and Calendula officinalis extract in a mass ratio of 2-5:1-3:1-2:2-3. This invention achieves a synergistic effect among the components through its rational formulation.

The invention relates to a composition with effects of resisting saccharification, inhibiting RAGE and brightening as well as a preparation method, a preparation product and application of the composition, and belongs to the field of medical instruments, the field of medical or dressing preparations, the technical field of biological medicine manufacturing and the technical field of preparation manufacturing. The composition comprises an ormosia henryi bark extract, tetrahydrocurcumin, a mirabilis jalapa extracting solution, a surfactant, polyol, phospholipid and a solvent. The preparation method provided by the invention comprises the following steps: mixing and dissolving 1, 3-butanediol, a surfactant, an ormosia henryi bark extract and tetrahydrocurcumin, wherein the 1, 3-butanediol accounts for 25-35% of the formula amount of 1, 3-butanediol; according to the method, the illumination stability and the high-temperature stability of the obtained composition are improved, and the method has unexpected technical effects, is simple to operate, does not need equipment such as high-pressure averaging equipment, and is low in equipment cost. In addition, the composition provided by the invention is high in bioavailability, and has good antioxidant and brightening effects, lipofuscin and RAGE level inhibition effects and the like.

This application relates to the field of anti-wrinkle and firming skincare products, and more specifically, to an anti-wrinkle and firming composition that helps collagen absorption, retention, and skin filling. An anti-wrinkle and firming composition that helps collagen absorption, retention, and skin filling comprises, by weight percentage: 0.05-1% collagen, 0.1-5% perilla extract, 0.1-5% four o'clock flower extract, 0.1-5% goldenrod extract, 0.1-5% centella asiatica extract, 0.1-5% white truffle extract, and a solvent. This application can help collagen absorption, retention, and skin filling, further enhancing the anti-wrinkle and firming effect.

The preparation method comprises the following steps: S1, taking a fresh mirabilis jalapa plant as an extracted part, and extracting the mirabilis jalapa plant to obtain a mirabilis jalapa extract with high mirabilis jalapa amide; s2, mixing the extracted part with a bacillus subtilis solution; then placing for 24-48 hours, and sterilizing; s3, immersing the extracted part into alcohol for extraction, and taking an extracting solution part; concentrating under reduced pressure to obtain a concentrated solution; s4, extracting the concentrated solution by using organic ester to obtain an extracting solution; and S5, carrying out desolventizing treatment on the extracting solution to obtain the chrysanthemum indicum extract. The method comprises the following steps: pre-treating fresh euphorbia helioscopia plants by using a bacillus subtilis solution; and the yield of the vermilion amide in the extract can be obviously improved. According to the method, recyclable alcohols and organic esters are used as extraction solvents, extraction process parameters are optimized, and the extraction efficiency and the final effective component content are optimized.

The present invention provides a soothing / anti-sensitivity composition, comprising raw materials in the following parts by weight: 9-20 parts of dendrobium nobile extract; 5-15 parts of tropaeolum majus extract; 5-15 parts of calendula officinalis extract; 1-3 parts of anthyllis vulneraria extract; 0.1-0.5 part of mirabilis jalapa extract. By applying the formula theory of "sovereign, minister, assistant and guide" in traditional Chinese medicine, the plant extracts are reasonably combined, and the components synergistically enhance each other, so as to effectively inhibit the skin inflammatory reaction, thereby achieving the effects of soothing and anti-inflammatory, repairing damaged skin. At the same time, by inhibiting the TRPV1 (transient receptor potential cation channel 1) signal transduction, the expression of pro-inflammatory factors such as IL-6, IL-8, and PGE2 is reduced, thereby reducing the over-sensitive state of the epidermis, and applying it to cosmetic products.