Compound foot bath tablet as well as preparation method and application thereof

Abstract

The invention relates to the technical field of preparation of health-care products, and provides a compound foot bath tablet as well as a preparation method and application thereof. The compound foot bath tablet comprises the following components: a monarch drug, a ministerial drug, an adjuvant drug, a conductant drug and auxiliary materials. Wherein the monarch drug comprises a rhodiola rosea extract, safflower, a lucid ganoderma extract, sea-buckthorn and crocus sativus salt; the ministerial drugs comprise fructus chebulae extract, fructus terminaliae billericae extract, emblic leafflower fruit extract, fructus schizandrae extract, radix codonopsis, radix salviae miltiorrhizae, herba leonuri, radix notoginseng, juniperus formosana, rhizoma kaempferiae extract, radix astragali seu hedysari, myricaria laxiflora, rhizoma chuanxiong, sea salt, herba artemisiae annuae, lavender and mirabilis jalapa extract; the adjuvant drugs comprise gentiana macrophylla extract, gentian extract, rhizoma bolbostemmae extract, divaricate saposhnikovia root, citrus peel, sappan wood, perilla leaf, herba lycopi extract, cowherb seed extract, tribulus terrestris, rhododendron and rheum palmatum; the conductant drug comprises gastrodia elata and calamus; the auxiliary materials comprise an effervescing agent, a disintegrating agent and an adhesive. The compound foot bath tablet can clear damp and help sleep, and is convenient to use, safe and reliable.

Description

Technical Field

[0001] This application relates to the field of health product preparation technology, and in particular to a compound foot bath tablet, its preparation method and uses. Background Technology

[0002] The use of herbal foot baths in traditional Chinese medicine has a long history in my country. Foot baths can relieve fatigue, improve blood circulation, promote metabolism, and bring physical and mental comfort and refreshment. Tibetan medicinal bathing, known as "Takimu" in Tibetan, is a traditional knowledge and practice of the Tibetan people. Guided by the "five elements" of life (earth, water, fire, wind, and space) and the "three causes" of health and disease (Lung, Tripa, and Pekan), it involves bathing in natural hot springs or water or steam boiled with medicinal herbs to regulate the balance of body and mind, achieving health and disease prevention. Immersing the whole body or parts of the body in Tibetan medicinal liquid, under the heat of the water and the medicinal properties, opens the pores and unblocks the meridians, allowing the effective components of the ingredients to enter the body.

[0003] In modern society, due to changes in lifestyle, such as prolonged exposure to air conditioning, lack of exercise, and irregular eating habits, more and more people are suffering from excessive dampness in their bodies. Dampness not only causes various uncomfortable symptoms such as heaviness in the body, joint pain, and itchy skin, but also seriously affects sleep quality, leading to insomnia and excessive dreaming. Chronic sleep deprivation further impacts health, creating a vicious cycle. Therefore, researching a health product that can remove dampness and promote sleep, and is convenient, safe, and reliable, has broad market prospects. Summary of the Invention

[0004] In view of this, this application aims to provide a compound foot bath tablet that can provide a health care product that is convenient to use, safe and reliable, and helps to remove dampness and promote sleep.

[0005] To achieve the above objectives, the technical solution of this application is implemented as follows: A compound foot bath tablet, wherein the components of the compound foot bath tablet include principal drug, assistant drug, adjuvant drug, guiding drug and excipients; The principal ingredients include Rhodiola rosea extract, safflower, Ganoderma lucidum extract, sea buckthorn, and saffron salt; The medicinal ingredients include Terminalia chebula extract, Terminalia chebula extract, Phyllanthus emblica extract, Schisandra chinensis extract, Codonopsis pilosula, Salvia miltiorrhiza, Leonurus japonicus, Panax notoginseng, Juniperus chinensis, Kaempferia galanga extract, Astragalus membranaceus, Myrica rubra, Ligusticum chuanxiong, sea salt, Artemisia annua, lavender, and Mirabilis jalapa extract; The adjuvants include extracts of Gentiana macrophylla, Gentiana scabra, Fritillaria cirrhosa, Saposhnikovia divaricata, Citrus reticulata peel, Caesalpinia sappan, Perilla frutescens leaf, Lycopus lucidus extract, Vaccaria segetalis extract, Tribulus terrestris, Rhododendron molle, and Rheum palmatum. The medicinal ingredients include Gastrodia elata and Acorus tatarinowii; The excipients include effervescent agents, disintegrants, and binders.

[0006] Furthermore, the saffron salt is made from natural crystalline salt from the Zabuye Salt Lake in Tibet.

[0007] Furthermore, the particle size of the natural crystalline salt is between 80 mesh and 120 mesh, and the NaCl content is ≤60%.

[0008] Furthermore, the effervescent agent comprises citric acid and sodium bicarbonate; and / or, The disintegrant is croscarmellose sodium; and / or The adhesive is hydroxypropyl methylcellulose.

[0009] Furthermore, the components of the compound foot bath tablets include, by weight percentage, 15%-30% of the principal drug, 25%-40% of the assistant drug, 10%-20% of the adjuvant drug, 5%-10% of the guiding drug and 15%-25% of the excipients.

[0010] Compared with the prior art, this application has the following advantages: Regarding the compound foot bath tablets of this application, from the perspective of traditional Chinese medicine theory, the pungent and warm properties of juniper in the tablets, combined with the warming and meridian-clearing effects of saffron salt, enhance the overall formula's ability to resolve blood stasis caused by cold and dampness. Juniper, galangal, and lavender work synergistically to exert anti-inflammatory and analgesic effects. Galangal is more warming and pain-relieving, lavender is more nerve-soothing, and juniper is more wind-dispelling and meridian-clearing, forming an anti-inflammatory closed loop of "external application (meridian clearing) + internal regulation (pain relief)," assisting rhodiola and safflower in relieving pain associated with blood stasis. The wind-dispelling and dampness-removing effects of juniper, combined with the "wind-dispelling and exterior-releasing" effects of saposhnikovia and the "wind-dampness-clearing and meridian-clearing" effects of gentian, strengthen the clearance of pathological factors of "rheumatic obstruction," clearing obstacles for the blood-activating effects of the principal herbs.

[0011] Meanwhile, Rhodiola rosea combats hypoxia, Hippophae rhamnoides strengthens the spleen and eliminates dampness, and the diuretic and meridian-clearing effects of Myricaria rubra can help expel dampness and turbidity from the body, preventing dampness from obstructing qi and blood, and enhancing the efficiency of Rhodiola rosea in promoting qi and blood circulation. Leonurus japonicus invigorates blood and regulates menstruation, and Lycopus lucidus invigorates blood and promotes diuresis. Myricaria rubra can work synergistically with these two to form a combination of "invigorating blood and promoting diuresis." Stagnation of dampness is often accompanied by blood stasis, and the combined effect of these three can improve poor blood circulation caused by edema and dampness. Rhubarb purges and eliminates stagnation, while Myricaria rubra promotes diuresis and eliminates dampness. The two expel pathological products (turbidity, stagnation, and dampness toxins) from the body through both "purging" and "drainage" pathways, preventing the retention of stagnation and turbidity from aggravating blood stasis, and indirectly strengthening the blood-invigorating effect of the principal herbs.

[0012] Furthermore, safflower invigorates blood and is warm in nature, while saffron salt is also warm. The bitter and cold nature of artemisia annua can neutralize the dryness and heat of both, preventing excessive blood invigoration from causing "blood stasis and heat," thus achieving "warming without generating heat." Salvia miltiorrhiza invigorates blood and cools blood, while amla nourishes yin and generates fluids. Artemisia annua works synergistically with these two to enhance the "cooling blood + nourishing yin" effect, clearing blood stasis and heat while preventing excessive blood cooling from damaging yang (salvia miltiorrhiza is slightly cooling, and artemisia annua can prevent cold stagnation by clearing away deficiency heat). Gentiana scabra clears heat and dries dampness, while fritillaria cirrhosa disperses nodules and detoxifies. The heat-clearing and anti-inflammatory effects of artemisia annua work synergistically with these two to enhance the clearance of "heat toxins" accompanying blood stasis.

[0013] Rhodiola rosea invigorates qi and combats hypoxia, while rhododendron dispels wind, eliminates dampness, and unblocks the meridians, forming a synergistic effect of "anti-hypoxia + eliminating the cause of the disease." Rhododendron, juniper, and saposhnikovia all belong to the category of dispelling wind and eliminating dampness. Juniper is more warming and invigorating, saposhnikovia is more diaphoretic, and rhododendron is more diaphoretic. Together, they cover the three evils of "wind, cold, and dampness," comprehensively clearing obstructive factors and opening up pathways for blood-activating herbs such as safflower and salvia miltiorrhiza. Tribulus terrestris calms the liver and dispels wind, while perilla leaves relieve exterior symptoms and dispel cold. Rhododendron works synergistically with these two to enhance the "wind-dispelling" effect, stopping spasms by dispelling wind and relieving pain by unblocking the meridians.

[0014] Reishi mushroom calms the mind and improves intelligence, regulating the nervous system; Gastrodia elata calms the liver and improves cerebral circulation. Together, they work synergistically on the nervous system, with Reishi mushroom focusing on "strengthening the body's resistance" and Gastrodia elata focusing on "eliminating pathogens." Together, they improve insufficient blood supply to the brain caused by blood stasis, strengthening the overall formula's "qi-tonifying and blood-activating" protection of the central nervous system. Ligusticum chuanxiong promotes qi and blood circulation, "ascending to the head and eyes," while Schisandra chinensis nourishes the heart and calms the mind. Gastrodia elata, along with the other two, forms a "blood-activating + mind-calming + meridian-guiding" combination. Ligusticum chuanxiong promotes qi and blood to the head orifices, Gastrodia elata guides the medicine into the brain, and Schisandra chinensis calms the mind. Together, these three alleviate headaches, dizziness, and insomnia caused by blood stasis and liver yang hyperactivity.

[0015] Citrus peel regulates qi and strengthens the spleen, calamus opens the orifices and resolves phlegm, and gastrodia elata calms the liver and extinguishes wind, working synergistically with the two to harmonize qi. When qi stagnates, blood stasis occurs. Citrus peel regulates qi to help blood circulation, calamus opens the orifices to unblock the brain meridians, and gastrodia elata extinguishes wind to stabilize the nerves. The three of them ensure the normal circulation of qi and blood in the head and face from the perspective of "regulating qi-opening the orifices-extinguishing wind", avoiding excessive disturbance of liver wind by blood-activating drugs.

[0016] On the other hand, regarding the mechanism of action of the active ingredients of each component in this embodiment, the principal drug group, Rhodiola rosea + saffron salt, can promote body fluid metabolism by regulating AQP4 aquaporin; the adjuvant drug group, Rheum palmatum + Lycopus lucidus, can activate TRPV1 ion channels to enhance sweating and thus synergistically regulate the dampness-removing pathway; the assistant drug group, Schisandra chinensis and lavender, can enhance GABA receptor activity to achieve a sleep-aiding effect; and the agonist drug group, Gastrodin in Gastrodia elata, can inhibit excessive release of glutamate to achieve a sleep-aiding effect.

[0017] Therefore, the compound foot bath tablets of this embodiment can promote blood circulation, remove blood stasis, eliminate dampness and aid sleep through the synergistic effect of each component. Moreover, the compound foot bath tablets are made from natural medicinal materials and do not contain any chemically synthesized ingredients. They have no toxic side effects on the human body and are safe and reliable.

[0018] Another object of this application is to provide a use of the above-mentioned compound foot bath tablets, specifically their application in removing dampness and aiding sleep.

[0019] Furthermore, the application includes: dissolving the compound foot bath tablets completely in hot water and then using it for a foot bath; The foot bath water temperature should be maintained between 40℃ and 45℃, and the soaking time should be between 20 minutes and 30 minutes.

[0020] This application also proposes a method for preparing compound foot bath tablets, the preparation method comprising: The following ingredients were pulverized and sieved: safflower, sea buckthorn, saffron salt, codonopsis, salvia miltiorrhiza, motherwort, notoginseng, juniper, astragalus, water cypress branch, chuanxiong, sea salt, artemisia annua, lavender, saposhnikovia divaricata, citrus peel, sappanwood, perilla leaf, tribulus terrestris, rhododendron, palm-leaved rhubarb, gastrodia elata, and calamus. The extracts of Rhodiola rosea, Ganoderma lucidum, Terminalia chebula, Terminalia chebula, Phyllanthus emblica, Schisandra chinensis, Kaempferia galanga, Mirabilis jalapa, Gentiana macrophylla, Fritillaria cirrhosa, Lycopus lucidus, and Vaccaria segetalis were spray-dried separately, mixed, and then prepared into a dry extract powder. The dry extract powder is mixed with sieved safflower, sea buckthorn, saffron salt, codonopsis, salvia miltiorrhiza, motherwort, notoginseng, juniper, astragalus, mulberry branch, ligusticum, sea salt, artemisia annua, lavender, saposhnikovia divaricata, citrus peel, sappanwood, perilla leaf, tribulus terrestris, rhododendron, rhubarb palmate leaf, gastrodia elata, calamus, as well as effervescent agent, disintegrant and binder to prepare a mixture. The compound foot bath tablets are prepared by compressing the mixture into tablets.

[0021] Furthermore, the Rhodiola rosea extract, Ganoderma lucidum extract, Terminalia chebula extract, Terminalia chebula extract, Phyllanthus emblica extract, Schisandra chinensis extract, Kaempferia galanga extract, Mirabilis jalapa extract, Gentiana macrophylla extract, Gentiana scabra extract, Fritillaria cirrhosa extract, Lycopus lucidus extract, and Vaccaria segetalis extract are all prepared by water extraction and alcohol precipitation or supercritical CO2 extraction.

[0022] Furthermore, the extraction pressure of the supercritical CO2 extraction is between 25 MPa and 35 MPa, and the temperature is between 40°C and 50°C.

[0023] Compared with the prior art, this application has the following advantages: The preparation method of the compound foot bath tablets in this application produces a tablet form that is easy to store and carry. When using it, simply dissolve it in hot water; no complicated operation steps are required, making it suitable for the fast-paced lifestyle of modern people. Attached Figure Description

[0024] The accompanying drawings, which form part of this application, are used to provide a further understanding of this application. The illustrative embodiments and descriptions of this application are used to explain this application and do not constitute an undue limitation of this application. In the drawings: Figure 1 This is a flowchart illustrating the preparation method of the compound foot bath tablets described in the embodiments of this application. Detailed Implementation

[0025] To make the technical solution and advantages of this application clearer, the following detailed description is provided in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative and not intended to limit the scope of this application.

[0026] It should be noted that, unless otherwise specified, the embodiments and features described in this application can be combined with each other.

[0027] For items where specific conditions are not specified in this application, conventional conditions or conditions recommended by the manufacturer of the equipment used shall apply. For items where the manufacturer of the reagents or instruments used is not specified, conventional products that can be purchased commercially shall be used. As for the technical means or processes involved, if specific conditions are not specified, they shall be carried out in accordance with the existing methods in the relevant field.

[0028] The present application will now be described in detail with reference to the accompanying drawings and embodiments.

[0029] An embodiment of the first aspect of this application provides a compound foot bath tablet that can provide a health care product that is convenient to use, safe and reliable, and helps to remove dampness and promote sleep.

[0030] Existing technologies offer a wide variety of products for removing dampness and aiding sleep, but most have limitations. Some products are taken orally, which may burden the digestive system and other organs, and may have certain side effects; some external foot bath products release their active ingredients slowly, resulting in poor efficacy, and are inconvenient to carry and use. Tibetan medicine, on the other hand, has a long history and unique theoretical system for regulating the body and improving sleep. Its abundant medicinal resources and unique processing methods can exert excellent efficacy.

[0031] In view of this, in order to overcome the shortcomings of the prior art, the compound foot bath tablet of this embodiment combines... Figure 1 In terms of overall design, the components include principal drug, assistant drug, adjuvant drug, guide drug and excipients.

[0032] It is worth noting that, in a preferred embodiment, the components of the compound foot bath tablets in this embodiment may, by weight percentage, include, for example, 15%-30% of the principal drug, 25%-40% of the assistant drug, 10%-20% of the adjuvant drug, 5%-10% of the guiding drug, and 15%-25% of the excipients.

[0033] In traditional Chinese medicine prescription theory, the principal herb is the core of the prescription and plays the main therapeutic role. In this embodiment, preferred principal herbs may include, for example, Rhodiola rosea extract, safflower, Ganoderma lucidum extract, sea buckthorn, and saffron salt.

[0034] Among them, Rhodiola rosea extract contains a variety of active ingredients such as rhodioloside, tyrosol, flavonoids, polysaccharides and amino acids, which can combat fatigue and improve endurance.

[0035] Safflower has the effects of promoting blood circulation, relieving menstrual cramps, dispersing blood stasis, and relieving pain. It can be used for chest pain, abdominal pain due to blood stasis, and injuries from falls.

[0036] Reishi extract is obtained by extracting and stabilizing the active ingredients in reishi mushrooms. The main active ingredients of reishi include polysaccharides, triterpenoids, polypeptides, and fatty acids. Polysaccharides are one of the main components of reishi extract, possessing various effects such as antioxidant, immunomodulatory, and anti-tumor properties. Triterpenoids are another important component of reishi, exhibiting hypoglycemic, antibacterial, anti-inflammatory, and anti-tumor effects.

[0037] Sea buckthorn is warm in nature and has a sour and astringent taste. It enters the liver, stomach, and large and small intestine meridians. It has the effects of relieving cough and expectoration, promoting digestion and resolving stagnation, and promoting blood circulation and removing blood stasis. It can be used for cough with excessive phlegm, indigestion, abdominal pain due to food stagnation, amenorrhea due to blood stasis, and swelling and bruising from falls.

[0038] Tibetan red salt is warm in nature, salty, bitter, and pungent in taste, and toxic. It enters the liver, spleen, and stomach meridians and has the effects of eliminating stagnation and dissipating nodules, as well as eroding sores and removing putrefaction. It can be used for abdominal masses, carbuncles, boils, pterygium, and nasal polyps. The Tibetan red salt used in this application is preferably, for example, natural crystalline salt from the Zabuye Salt Lake in Tibet.

[0039] It is worth noting that the natural crystalline salt used is from Zabuye Salt Lake in Tibet. Preferably, the natural crystalline salt has a particle size between 80 and 120 mesh and contains ≤60% NaCl.

[0040] Meanwhile, the assistant herbs are those that assist the principal herbs in strengthening the treatment of the primary disease or symptom, or in treating concurrent diseases or symptoms. In this embodiment, preferred assistant herbs may include, for example, extracts of Terminalia chebula, Phyllanthus emblica, Schisandra chinensis, Codonopsis pilosula, Salvia miltiorrhiza, Leonurus japonicus, Panax notoginseng, Juniperus chinensis, Kaempferia galanga, Astragalus membranaceus, Myrica rubra, Ligusticum chuanxiong, sea salt, Artemisia annua, lavender, and Mirabilis jalapa.

[0041] Among them, Terminalia chebula extract is neutral in nature, bitter, sour and astringent in taste, and enters the lung and large intestine meridians. It has the effects of astringing the intestines and lungs, reducing fire and relieving sore throat. It can be used for chronic diarrhea and dysentery, hematochezia and rectal prolapse, lung deficiency and cough, persistent cough, sore throat and hoarseness.

[0042] Terminalia chebula extract is a complex mixture extracted from the Terminalia chebula plant. It contains a variety of chemical components, including various alkaloids, sulfites, flavonoids, and polysaccharides, and has a variety of pharmacological activities such as anti-inflammatory, antioxidant, antibacterial, and antitumor effects. It is often used to treat diseases such as rheumatoid arthritis, chronic hepatitis, diabetes, and hypertension.

[0043] Codonopsis pilosula has a sweet taste and neutral properties. It has the effects of tonifying the middle energizer and replenishing qi, quenching thirst, strengthening the spleen and lungs, nourishing blood and promoting body fluid production. It can be used for spleen and lung qi deficiency, poor appetite and fatigue, cough and wheezing, qi and blood deficiency, sallow complexion, palpitations and shortness of breath, thirst due to fluid depletion, and internal heat and thirst. It is also used for symptoms such as lethargy, shortness of breath, weakness in the limbs, poor appetite, qi deficiency, deficiency of both qi and body fluids, deficiency of both qi and blood, and sallow complexion due to blood deficiency.

[0044] Danshen is bitter and slightly cold in nature, and enters the heart, pericardium and liver meridians. It has the effects of promoting blood circulation and removing blood stasis, regulating menstruation and relieving pain, and calming the mind and relieving irritability. It is mainly used to treat women's menstrual disorders, postpartum abdominal pain due to blood stasis, traumatic injuries, irritability and other diseases.

[0045] Motherwort is slightly cold in nature, bitter and pungent in taste, and enters the liver and pericardium meridians. It has the effects of promoting blood circulation and regulating menstruation, removing blood stasis, and promoting diuresis and reducing swelling. It can be used for irregular menstruation, threatened abortion, dystocia, retained placenta, postpartum hemorrhage, abdominal pain due to blood stasis, metrorrhagia, hematuria, hematochezia, carbuncles and sores.

[0046] Panax notoginseng is warm in nature, sweet and slightly bitter in taste, and enters the liver and stomach meridians. It has the effects of dispersing blood stasis, stopping bleeding, reducing swelling and relieving pain. It can be used for hemoptysis, hematemesis, epistaxis, hematochezia, metrorrhagia, traumatic bleeding, chest and abdominal pain, and swelling and pain from falls.

[0047] Juniper is cold in nature and bitter in taste. It has the effects of clearing heat and detoxifying, drying dampness and relieving itching. It can be used for measles with high fever, eczema and tinea.

[0048] Kaempferia galanga extract is warm in nature and pungent in taste. It enters the stomach meridian and has the effects of warming the middle, promoting digestion, and relieving pain. It can treat cold pain in the heart and abdomen, indigestion, traumatic injuries, toothache, and chest and diaphragm distension.

[0049] Astragalus is slightly warm in nature and sweet in taste. It has the effects of strengthening the spleen and replenishing the middle jiao, raising yang and lifting prolapse, benefiting wei qi and consolidating the exterior, promoting diuresis, and promoting tissue regeneration and detoxification. It is mainly used to treat spleen qi deficiency syndrome, lung qi deficiency syndrome, spontaneous sweating due to qi deficiency, qi and blood deficiency, sores that are difficult to ulcerate or heal, etc.

[0050] Water juniper has the effects of promoting diuresis and clearing the meridians, and promoting blood circulation and removing stagnation. In Tibetan medicine, it is often used to clear heat and dampness, clear the meridians and relieve pain. Modern research shows that it contains flavonoids, which have anti-edema and microcirculation-improving effects.

[0051] Chuanxiong is warm in nature and pungent in taste. It enters the liver, gallbladder and pericardium meridians. It has the effects of regulating qi and relieving depression, dispelling wind and drying dampness, promoting blood circulation and relieving pain. It can be used for wind-cold headache and dizziness, difficult labor, postpartum blood stasis and pain, carbuncles and sores, irregular menstruation, amenorrhea and dysmenorrhea, abdominal pain, chest and rib pain, traumatic swelling and pain, and rheumatic arthralgia.

[0052] Sea salt is warm in nature and has a salty and sweet taste. It contains ions that can maintain cell fluid volume and osmotic pressure, thereby maintaining the body's water balance and blood circulation.

[0053] Artemisia annua is cold in nature, bitter and slightly pungent in taste, and enters the liver and gallbladder meridians. It has the effects of clearing heat, relieving summer heat, eliminating steaming heat, and stopping malaria. It can treat febrile diseases, summer heat, bone steaming fever, malaria, dysentery, jaundice, scabies, and itching.

[0054] Lavender is cool in nature and pungent in taste. It has the effects of clearing heat and detoxifying, dispelling wind and relieving itching.

[0055] Mirabilis jalapa extract can be used as an antioxidant, moisturizer, and anti-inflammatory agent.

[0056] Adjuvant herbs are those that assist the principal and assistant herbs in enhancing their therapeutic effects, or directly treat secondary concurrent symptoms; or that restrain the harshness of the principal and assistant herbs, or reduce or eliminate their toxicity; or, depending on the needs of certain diseases, are small amounts of herbs that have opposite properties or effects to the principal herb but can still play a synergistic role in treatment. The potency of adjuvant herbs in a formula is less than that of assistant herbs, and they are generally used in lighter doses than the adjuvant herbs in the components of this example.

[0057] Preferred adjuvants in this embodiment may include, for example, extracts of Gentiana macrophylla, Gentiana scabra, Fritillaria cirrhosa, Saposhnikovia divaricata, Citrus reticulata peel, Caesalpinia sappan, Perilla frutescens leaf, Lycopus lucidus extract, Vaccaria segetalis extract, Tribulus terrestris, Rhododendron molle, and Rheum palmatum.

[0058] Specifically, the Gentiana macrophylla extract mainly contains active ingredients such as volatile oils, flavonoids and various alkaloids, and is often used to treat digestive system diseases such as spleen and stomach weakness, loss of appetite, abdominal distension and diarrhea.

[0059] Gentian extract mainly contains compounds such as gentiopicroside and gentiopicrin, which have antioxidant and anti-inflammatory effects.

[0060] The main active ingredients of Fritillaria cirrhosa extract are saponins and sterols, which have immunosuppressive, anticancer, antiviral and anti-inflammatory effects.

[0061] Saposhnikovia divaricata is warm in nature and has a pungent and sweet taste. It has the effects of releasing exterior pathogens, dispelling wind, eliminating dampness and relieving pain. It can treat exogenous wind-cold, headache, dizziness, stiff neck, wind-cold-dampness arthralgia, joint pain, limb spasms and tetanus.

[0062] The main components of citrus peel include citrus fiber, hesperidin, and vitamin C, which have antioxidant, anti-inflammatory, and immune-boosting functions.

[0063] Sappanwood is sweet, salty, slightly astringent, odorless, with a neutral nature, and belongs to the heart, liver, and spleen meridians. It has the effects of promoting blood circulation to remove blood stasis, reducing swelling and alleviating pain. It is commonly used to treat various symptoms of stasis pain, such as traumatic injuries, amenorrhea and dysmenorrhea, and abdominal pain.

[0064] Perilla leaf is warm in nature and pungent in taste. It can be used for common cold due to wind-cold, aversion to cold and fever, cough, asthma, chest and abdominal distension, and fetal restlessness.

[0065] The main components of the Eupatorium japonicum Thunb. extract are volatile oil, flavonoid glycosides, saponins, phenols, carbohydrates, and tannins. It has the effects of promoting blood circulation to remove blood stasis and promoting diuresis to reduce swelling. It is used for irregular menstruation, amenorrhea, dysmenorrhea, postpartum blood stasis abdominal pain, and edema.

[0066] The Vaccaria segetalis (Neck.) Garcke extract mainly contains compounds such as flavonoids, alkaloids, polysaccharides, and triterpenoid saponins. Among them, flavonoid glycoside compounds have the effects of reducing lipid, anti-arrhythmia, anti-inflammatory, antibacterial and antiviral, and laxative. Polysaccharides have the effects of immunomodulation, anti-tumor, reducing blood sugar and lipid, and anti-aging.

[0067] Tribulus terrestris L. is slightly warm in nature, pungent and bitter in taste. It has the effects of soothing the liver and relieving depression, promoting blood circulation and expelling wind, improving eyesight and relieving itching. It can be used for headache and dizziness, chest and hypochondrium distending pain, breast congestion and breast abscess, corneal nebula, and rubella itching.

[0068] Rhododendron simsii Planch. has the effects of dispelling wind and dampness, helping to dredge collaterals and relieve pain. The flavonoid components it contains can play the roles of anti-inflammatory, analgesic, and improving joint circulation.

[0069] Rheum palmatum L. is bitter in taste and cold in nature. It has the effects of inducing purgation to promote defecation, purging fire and cooling blood, promoting blood circulation to remove blood stasis, and clearing heat and detoxifying.

[0070] In addition, the adjuvant drug, one is the drug guiding the meridian, that is, the drug that can lead all the drugs in the prescription to the affected area; the other is the drug for harmonizing, that is, the drug with the function of harmonizing all the drugs. Its medicinal power in the prescription is relatively small and the dosage is also light. The adjuvant drugs in this embodiment preferably include, for example, Gastrodia elata Blume and Acorus calamus L.

[0071] Among them, Gastrodia elata Blume is rich in gastrodin and has the effects of suppressing liver wind and stopping convulsions, suppressing hyperactive liver yang, and expelling wind and dredging collaterals. It can improve nerve function and relieve dizziness and headache.

[0072] Acorus calamus L. is slightly warm in nature, pungent and bitter in taste. It has the effects of opening the orifices, resolving phlegm, regulating qi, promoting blood circulation, expelling wind, and removing dampness. It can be used for epilepsy, syncope due to phlegm, coma due to febrile disease, amnesia, qi obstruction and deafness, chest distress, stomachache, abdominal pain, wind-cold-dampness arthralgia, carbuncle and swelling toxin, and traumatic injury.

[0073] The excipients in this embodiment preferably include, for example, effervescent agents, disintegrants, and binders.

[0074] Specifically, the above-mentioned effervescent agents preferably include, for example, citric acid and sodium bicarbonate.

[0075] The preferred disintegrant is, for example, sodium croscarmellose.

[0076] The adhesive described above can preferably be, for example, hydroxypropyl methylcellulose.

[0077] Based on the above introduction of each component, from the perspective of traditional Chinese medicine theory, the pungent and warm properties of juniper in the compound foot bath tablets of this embodiment, combined with the warming and meridian-clearing effects of saffron salt, can enhance the overall formula's ability to resolve blood stasis caused by cold and dampness stagnation, making it particularly suitable for qi and blood stagnation caused by wind-cold-dampness arthralgia. Juniper, galangal, and lavender all contain volatile oils, which synergistically exert anti-inflammatory and analgesic effects. Galangal is more warming and analgesic, lavender is more nerve-soothing, and juniper is more wind-dispelling and meridian-clearing, forming an anti-inflammatory closed loop of "external application (meridian clearing) + internal regulation (pain relief)," assisting rhodiola rosea and safflower in relieving pain associated with blood stasis. The wind-dispelling and dampness-removing effects of juniper, combined with the "wind-dispelling and exterior-releasing" effects of saposhnikovia and the "wind-dampness-clearing and meridian-clearing" effects of gentian, strengthen the clearance of pathological factors of "wind-dampness obstruction," clearing obstacles for the blood-activating effects of the principal herbs.

[0078] Meanwhile, Rhodiola rosea combats hypoxia, Hippophae rhamnoides strengthens the spleen and eliminates dampness, and the diuretic and meridian-clearing effects of Myricaria rubra can help expel dampness and turbidity from the body, preventing dampness from obstructing qi and blood, and enhancing the efficiency of Rhodiola rosea in promoting qi and blood circulation. Leonurus japonicus invigorates blood and regulates menstruation, and Lycopus lucidus invigorates blood and promotes diuresis. Myricaria rubra can work synergistically with these two to form a combination of "invigorating blood and promoting diuresis." Stagnation of dampness is often accompanied by blood stasis. The combined effect of these three can improve poor blood circulation caused by edema and dampness, and is especially suitable for gynecological or limb edema accompanied by blood stasis. Rhubarb purges and eliminates stagnation, while Myricaria rubra promotes diuresis and eliminates dampness. The two expel pathological products (turbidity, stagnation, and dampness) from the body through two pathways: "purging" and "draining," preventing the retention of stagnation and turbidity from aggravating blood stasis, and indirectly strengthening the blood-invigorating effect of the principal herbs.

[0079] Furthermore, safflower invigorates blood and is warm in nature, while saffron salt is also warm. The bitter and cold nature of artemisia annua can neutralize the dryness and heat of both, preventing excessive blood invigoration from causing "blood stasis and heat," thus achieving "warming without generating heat." Salvia miltiorrhiza invigorates blood and cools blood, while amla nourishes yin and generates fluids. Artemisia annua works synergistically with both to enhance the "cooling blood + nourishing yin" effect. For blood stasis with heat syndrome, it clears blood stasis and heat while preventing excessive cooling of blood from damaging yang (salvia miltiorrhiza is slightly cooling, and artemisia annua can prevent cold coagulation by clearing away deficiency heat). Gentiana scabra clears heat and dries dampness, while fritillaria cirrhosa disperses nodules and detoxifies. The heat-clearing and anti-inflammatory effects of artemisia annua work synergistically with both to enhance the clearance of "heat toxins" accompanying blood stasis, making it especially suitable for inflammation caused by blood stasis and heat.

[0080] Rhodiola rosea invigorates qi and combats hypoxia, while rhododendron dispels wind and dampness and unblocks the meridians. Together, they can improve limb hypoxia and pain caused by rheumatic obstruction. Rheumatic obstruction of the meridians leads to poor blood and qi circulation; Rhodiola rosea enhances tissue tolerance to hypoxia, while rhododendron clears wind and dampness to unblock the meridians, forming a synergistic effect of "anti-hypoxia + eliminating the cause." Rhododendron, juniper, and saposhnikovia all belong to the category of dispelling wind and dampness. Juniper is warming and invigorating, saposhnikovia is diaphoretic, and rhododendron is diaphoretic. Together, they cover the three evils of "wind, cold, and dampness," comprehensively clearing obstructive factors and opening pathways for blood-activating herbs such as safflower and salvia miltiorrhiza. Tribulus terrestris calms the liver and dispels wind, while perilla leaves relieve exterior symptoms and dispel cold. Rhododendron, together with these two, strengthens the "wind-dispelling" effect, especially suitable for symptoms of blood stasis accompanied by "wind disturbance" (such as limb numbness, itching, and dizziness), stopping spasms by dispelling wind and relieving pain by unblocking the meridians.

[0081] Reishi mushroom calms the mind and improves intelligence, regulating the nervous system; Gastrodia elata calms the liver and improves cerebral circulation. Together, they work synergistically on the nervous system, with Reishi mushroom focusing on "strengthening the body's resistance" and Gastrodia elata focusing on "eliminating pathogens," improving insufficient blood supply to the brain caused by blood stasis and strengthening the overall formula's "qi-tonifying and blood-activating" protection of the central nervous system. Ligusticum chuanxiong promotes qi and blood circulation, "ascending to the head and eyes," while Schisandra chinensis nourishes the heart and calms the mind. Gastrodia elata, along with the other two, forms a "blood-activating + mind-calming + meridian-guiding" combination. Ligusticum chuanxiong promotes qi and blood to the head orifices, Gastrodia elata guides the medicine into the brain, and Schisandra chinensis calms the mind. Together, these three alleviate headaches, dizziness, and insomnia caused by blood stasis and liver yang hyperactivity. Citrus peel regulates qi and strengthens the spleen, calamus opens the orifices and resolves phlegm, and gastrodia elata calms the liver and extinguishes wind, working synergistically with the two to harmonize qi. When qi stagnates, blood stasis occurs. Citrus peel regulates qi to help blood circulation, calamus opens the orifices to unblock the brain meridians, and gastrodia elata extinguishes wind to stabilize the nerves. The three of them ensure the normal circulation of qi and blood in the head and face from the perspective of "regulating qi-unblocking the orifices-extinguishing wind", avoiding excessive disturbance of liver wind by blood-activating drugs.

[0082] On the other hand, regarding the mechanism of action of the active ingredients of each component in this embodiment, the principal drug group, Rhodiola rosea + saffron salt, can promote body fluid metabolism by regulating AQP4 aquaporin; the adjuvant drug group, Rheum palmatum + Lycopus lucidus, can activate TRPV1 ion channels to enhance sweating and thus synergistically regulate the dampness-removing pathway; the assistant drug group, Schisandra chinensis and lavender, can enhance GABA receptor activity to achieve a sleep-aiding effect; and the agonist drug group, Gastrodin in Gastrodia elata, can inhibit excessive release of glutamate to achieve a sleep-aiding effect.

[0083] Therefore, the compound foot bath tablets of this embodiment can achieve the effects of removing dampness, promoting sleep, and activating blood circulation and removing blood stasis through the synergistic effect of each component.

[0084] The second aspect of this application provides a use of the above-mentioned compound foot bath tablets. The application of the compound foot bath tablets in removing dampness and aiding sleep in this embodiment may include, for example, the following: dissolving the compound foot bath tablets completely in hot water and then taking a foot bath; maintaining the foot bath water temperature between 40℃ and 45℃ and soaking time between 20min and 30min.

[0085] It is worth noting that the hot water used in the above application process is preferably, for example, water at 40℃-50℃.

[0086] An embodiment of the third aspect of this application provides a method for preparing compound foot bath tablets, the method comprising the following steps: Step S1: Grind and sieve the following ingredients separately: safflower, sea buckthorn, saffron salt, codonopsis, salvia miltiorrhiza, motherwort, notoginseng, juniper, astragalus, water cypress branch, chuanxiong, sea salt, artemisia annua, lavender, saposhnikovia divaricata, citrus peel, sappanwood, perilla leaf, tribulus terrestris, rhododendron, palm-leaved rhubarb, gastrodia elata, and calamus.

[0087] Step S2: Spray dry the following extracts separately: Rhodiola rosea extract, Ganoderma lucidum extract, Terminalia chebula extract, Terminalia chebula extract, Phyllanthus emblica extract, Schisandra chinensis extract, Kaempferia galanga extract, Mirabilis jalapa extract, Gentiana macrophylla extract, Fritillaria cirrhosa extract, Lycopus lucidus extract, and Vaccaria segetalis extract, then mix them to obtain a dry extract powder.

[0088] The extraction methods for Rhodiola rosea extract, Ganoderma lucidum extract, Terminalia chebula extract, Terminalia chebula extract, Phyllanthus emblica extract, Schisandra chinensis extract, Kaempferia galanga extract, Mirabilis jalapa extract, Gentiana macrophylla extract, Fritillaria cirrhosa extract, Lycopus lucidus extract, and Vaccaria segetalis extract in step S2 above can, as preferred embodiments, be water extraction and alcohol precipitation or supercritical CO2 extraction.

[0089] It is worth noting that the above-mentioned supercritical CO2 extraction, as a preferred embodiment, can be carried out under extraction conditions such as an extraction pressure between 25 MPa and 35 MPa and a temperature between 40°C and 50°C.

[0090] Step S3: Mix the dry powder with sifted safflower, sea buckthorn, saffron salt, codonopsis, salvia miltiorrhiza, motherwort, notoginseng, juniper, astragalus, water cypress branch, chuanxiong, sea salt, artemisia annua, lavender, saposhnikovia divaricata, citrus peel, sappanwood, perilla leaf, tribulus terrestris, rhododendron, palm-leaved rhubarb, gastrodia elata, calamus, as well as effervescent agent, disintegrant and binder to obtain the mixture.

[0091] Step S4: Compress the mixture into tablets to obtain the compound foot bath tablets.

[0092] The compound foot bath tablets prepared by the method described in this embodiment are easy to store and carry. When using them, simply dissolve them in hot water; no complicated steps are required, making them suitable for the fast-paced lifestyle of modern people.

[0093] It is worth noting that, regarding the compound foot bath tablets, their preparation method, and uses in this embodiment, based on the above preferred embodiments, the following preparation examples can be referred to in specific implementation.

[0094] Example 1 Example 1 describes the preparation of the above-mentioned compound foot bath tablets. The formula and specific preparation steps are as follows: Formula: Principal drug group (20wt%): Rhodiola rosea extract, safflower extract, Ganoderma lucidum extract, sea buckthorn, saffron salt; Assistant drug group (40wt%): Terminalia chebula extract, Terminalia chebula extract, Phyllanthus emblica extract, Schisandra chinensis extract, Codonopsis pilosula, Salvia miltiorrhiza, Leonurus japonicus, Panax notoginseng, Juniperus chinensis, Kaempferia galanga extract, Astragalus membranaceus, Myrica rubra, Ligusticum chuanxiong, sea salt, Artemisia annua, Lavender, Mirabilis jalapa extract; Adjuvant drug group (20wt%): Gentiana macrophylla extract, Gentiana scabra extract, Fritillaria cirrhosa extract, Saposhnikovia divaricata, Citrus reticulata peel, Caesalpinia sappan, Perilla frutescens leaf, Lycopus lucidus extract, Vaccaria segetalis extract, Tribulus terrestris, Rhododendron molle, Rheum palmatum extract; Guide drug group (5wt%): Gastrodia elata, Acorus tatarinowii; Excipient group (15wt%): Effervescent agent (citric acid + sodium bicarbonate), disintegrant (cross-linked carboxymethyl cellulose sodium), binder (hydroxypropyl methylcellulose).

[0095] According to the above formula, the specific preparation steps are as follows: Step S1: Grind and sieve the following ingredients separately: safflower, sea buckthorn, saffron salt, codonopsis, salvia miltiorrhiza, motherwort, notoginseng, juniper, astragalus, water cypress branch, chuanxiong, sea salt, artemisia annua, lavender, saposhnikovia divaricata, citrus peel, sappanwood, perilla leaf, tribulus terrestris, rhododendron, palm-leaved rhubarb, gastrodia elata, and calamus. Step S2: Spray dry the following extracts separately: Rhodiola rosea extract, Ganoderma lucidum extract, Terminalia chebula extract, Terminalia chebula extract, Phyllanthus emblica extract, Schisandra chinensis extract, Kaempferia galanga extract, Mirabilis jalapa extract, Gentiana macrophylla extract, Fritillaria cirrhosa extract, Lycopus lucidus extract, and Vaccaria segetalis extract, then mix them to obtain a dry extract powder. Step S3: Mix the dry powder with sifted safflower, sea buckthorn, saffron salt, codonopsis, salvia miltiorrhiza, motherwort, notoginseng, juniper, astragalus, water cypress branch, chuanxiong, sea salt, artemisia annua, lavender, saposhnikovia divaricata, citrus peel, sappanwood, perilla leaf, tribulus terrestris, rhododendron, palm-leaved rhubarb, gastrodia elata, calamus, as well as effervescent agent, disintegrant and binder to prepare a mixture. Step S4: Compress the mixture into tablets to obtain compound foot bath tablets.

[0096] Example 2 Example 2 describes the preparation of the above-mentioned compound foot bath tablets. The formula and specific preparation steps are as follows: Formula: Principal drug group (30wt%): Rhodiola rosea extract, safflower extract, Ganoderma lucidum extract, sea buckthorn, saffron salt; Assistant drug group (30wt%): Terminalia chebula extract, Terminalia chebula extract, Phyllanthus emblica extract, Schisandra chinensis extract, Codonopsis pilosula, Salvia miltiorrhiza, Leonurus japonicus, Panax notoginseng, Juniperus chinensis, Kaempferia galanga extract, Astragalus membranaceus, Myrica rubra, Ligusticum chuanxiong, sea salt, Artemisia annua, Lavender, Mirabilis jalapa extract; Adjuvant drug group (10wt%): Gentiana macrophylla extract, Gentiana scabra extract, Fritillaria cirrhosa extract, Saposhnikovia divaricata, Citrus reticulata peel, Caesalpinia sappan, Perilla frutescens leaf, Lycopus lucidus extract, Vaccaria segetalis extract, Tribulus terrestris, Rhododendron molle, Rheum palmatum extract; Guide drug group (10wt%): Gastrodia elata, Acorus tatarinowii; Excipient group (20wt%): Effervescent agent (citric acid + sodium bicarbonate), Disintegrant (cross-linked carboxymethyl cellulose sodium), Binder (hydroxypropyl methylcellulose) Preparation steps: Same as the preparation steps in Example 1. Verification Example This verification example demonstrates the therapeutic effects of the compound foot bath tablets prepared in Examples 1 and 2 on individuals with high humidity levels and poor sleep quality.

[0097] For the compound foot bath tablets mentioned in Example 1 above, 50 volunteers with high levels of dampness and poor sleep quality were selected and used the compound foot bath tablets according to the above application method (soaking time of 20-30 minutes, water temperature maintained at 40-45℃, 5 times a week). After 4 weeks of continuous use, the verification results are shown in Table 1 below.

[0098] Table 1. Statistics on symptom improvement before and after 4 weeks of continuous use of compound foot bath tablets (n=50)

[0099] Note: P-value: Paired t-test (or Wilcoxon signed-rank test, depending on the normality of the data) was used to compare differences before and after the application. P < 0.05 indicates statistical significance. Improvement rate (%): Calculated based on subjects' self-report results. The total improvement rate is the sum of the proportions of "significant improvement" and "improvement". Total score for dampness symptoms: Example score range; the actual range should be set according to the scale used. PSQI total score: >5 points generally indicates poor sleep quality, ≤5 points indicates good sleep quality. The higher the score, the worse the sleep quality.

[0100] As shown in Table 1, after four weeks of standardized use, the subjects exhibited significant improvements in objective sleep indicators: the average sleep latency decreased by approximately 16.7 minutes, the average number of nighttime awakenings decreased by 1.4, the average total sleep time increased by 0.8 hours, and the average sleep efficiency improved by 9.4 percentage points. Simultaneously, the total score for dampness symptoms significantly decreased (average improvement of 11.7 points), and the total PSQI score also significantly decreased (average improvement of 3.7 points), indicating an overall improvement in sleep quality. Subject self-reports further corroborated these objective indicators, with 92% of subjects reporting improved dampness symptoms and 92% reporting improved sleep quality. In conclusion, the compound foot bath tablets prepared in Example 1 demonstrate significant efficacy in improving dampness symptoms and enhancing sleep quality in individuals with severe dampness.

[0101] For the compound foot bath tablets mentioned in Example 2 above, another 50 volunteers with high levels of dampness and poor sleep quality were selected and used the compound foot bath tablets according to the above application method (soaking time of 20-30 minutes, water temperature maintained at 40-45℃, 5 times a week). After 8 weeks of continuous use, the verification results are shown in Table 2 below.

[0102] Table 2. Statistical analysis of symptom improvement before and after 8 weeks of continuous use of compound foot bath tablets (n=50)

[0103] Note: P-value: Paired t-test (or Wilcoxon signed-rank test, depending on the normality of the data) was used to compare differences before and after the application. P < 0.05 indicates statistical significance. Improvement rate (%): Calculated based on subjects' self-report results. The total improvement rate is the sum of the proportions of "significant improvement" and "improvement". Total score for dampness symptoms: Example score range; the actual range should be set according to the scale used. PSQI total score: >5 points usually indicates poor sleep quality, ≤5 points indicates good sleep quality. The higher the score, the worse the sleep quality.

[0104] As shown in Table 2, after 8 weeks of continuous use of the compound foot bath tablets prepared in Example 2, the subjects showed significant and greater improvements in all indicators (compared to the results of 4 weeks in Example 1): Dampness symptoms: The total score for dampness symptoms decreased by an average of 16.6 points (P<0.001), a significant decrease. Up to 98% of the subjects reported improvement in dampness symptoms. Sleep quality: The sleep latency was significantly shortened by 23.4 minutes, the number of nighttime awakenings decreased significantly by 2.0 times, the total sleep time increased significantly by 1.4 hours, and sleep efficiency improved by 13.5 percentage points (all P<0.001). PSQI total score: The average decrease was 5.3 points (P<0.001), significantly lower than the diagnostic threshold (5 points), indicating that the overall sleep quality reached a "good" level. 98% of the subjects reported improvement in sleep quality.

[0105] In summary, the preparation method of the Tibetan bath foot tablets for removing dampness and aiding sleep of the present invention is simple and feasible, the product has significant effects in removing dampness and aiding sleep, and is convenient, safe and reliable to use, and has broad market application prospects.

[0106] The above descriptions are merely some embodiments of this application and are not intended to limit this application. The technical features or structures in the foregoing different embodiments can be arbitrarily combined to form other specific technical solutions as needed. For those skilled in the art, this application can have various modifications and variations. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of this application should be included within the scope of protection of the claims of this application.

Claims

1. A compound foot bath tablet, characterized in that: The compound foot bath tablets consist of principal drug, assistant drug, adjuvant drug, guiding drug, and excipients; The principal ingredients include Rhodiola rosea extract, safflower, Ganoderma lucidum extract, sea buckthorn, and saffron salt; The medicinal ingredients include Terminalia chebula extract, Terminalia chebula extract, Phyllanthus emblica extract, Schisandra chinensis extract, Codonopsis pilosula, Salvia miltiorrhiza, Leonurus japonicus, Panax notoginseng, Juniperus chinensis, Kaempferia galanga extract, Astragalus membranaceus, Myrica rubra, Ligusticum chuanxiong, sea salt, Artemisia annua, lavender, and Mirabilis jalapa extract; The adjuvants include extracts of Gentiana macrophylla, Gentiana scabra, Fritillaria cirrhosa, Saposhnikovia divaricata, Citrus reticulata peel, Caesalpinia sappan, Perilla frutescens leaf, Lycopus lucidus extract, Vaccaria segetalis extract, Tribulus terrestris, Rhododendron molle, and Rheum palmatum. The medicinal ingredients include Gastrodia elata and Acorus tatarinowii; The excipients include effervescent agents, disintegrants, and binders.

2. The compound foot bath tablet according to claim 1, characterized in that: The Tibetan red salt is made from natural crystalline salt from the Zabuye Salt Lake in Tibet.

3. The compound foot bath tablet according to claim 2, characterized in that: The natural crystalline salt has a particle size between 80 and 120 mesh and contains ≤60% NaCl.

4. The compound foot bath tablet according to claim 1, characterized in that: The effervescent agent comprises citric acid and sodium bicarbonate; and / or, The disintegrant is croscarmellose sodium; and / or The adhesive is hydroxypropyl methylcellulose.

5. The compound foot bath tablet according to claim 1, characterized in that: The compound foot bath tablets comprise, by weight percentage, 15%-30% of the principal drug, 25%-40% of the assistant drug, 10%-20% of the adjuvant drug, 5%-10% of the guiding drug, and 15%-25% of the excipients.

6. The use of the compound foot bath tablets as described in any one of claims 1-5, characterized in that: The application of the compound foot bath tablets in removing dampness and promoting sleep.

7. The use of the compound foot bath tablets according to claim 6, characterized in that, The applications include: Dissolve the compound foot bath tablets completely in hot water and then use the solution for a foot bath. The foot bath water temperature should be maintained between 40℃ and 45℃, and the soaking time should be between 20 minutes and 30 minutes.

8. A method for preparing compound foot bath tablets, characterized in that, The preparation method includes: The following ingredients were pulverized and sieved: safflower, sea buckthorn, saffron salt, codonopsis, salvia miltiorrhiza, motherwort, notoginseng, juniper, astragalus, water cypress branch, chuanxiong, sea salt, artemisia annua, lavender, saposhnikovia divaricata, citrus peel, sappanwood, perilla leaf, tribulus terrestris, rhododendron, palm-leaved rhubarb, gastrodia elata, and calamus. The extracts of Rhodiola rosea, Ganoderma lucidum, Terminalia chebula, Terminalia chebula, Phyllanthus emblica, Schisandra chinensis, Kaempferia galanga, Mirabilis jalapa, Gentiana macrophylla, Fritillaria cirrhosa, Lycopus lucidus, and Vaccaria segetalis were spray-dried separately, mixed, and then prepared into a dry extract powder. The dry extract powder is mixed with sieved safflower, sea buckthorn, saffron salt, codonopsis, salvia miltiorrhiza, motherwort, notoginseng, juniper, astragalus, mulberry branch, ligusticum, sea salt, artemisia annua, lavender, saposhnikovia divaricata, citrus peel, sappanwood, perilla leaf, tribulus terrestris, rhododendron, rhubarb palmate leaf, gastrodia elata, calamus, as well as effervescent agent, disintegrant and binder to prepare a mixture. The compound foot bath tablets are prepared by compressing the mixture into tablets.

9. The method for preparing the compound foot bath tablets according to claim 8, characterized in that: The Rhodiola rosea extract, Ganoderma lucidum extract, Terminalia chebula extract, Terminalia chebula extract, Phyllanthus emblica extract, Schisandra chinensis extract, Kaempferia galanga extract, Mirabilis jalapa extract, Gentiana macrophylla extract, Gentiana scabra extract, Fritillaria cirrhosa extract, Lycopus lucidus extract, and Vaccaria segetalis extract were all prepared by water extraction and alcohol precipitation or supercritical CO2 extraction.

10. The method for preparing the compound foot bath tablets according to claim 9, characterized in that: The supercritical CO2 extraction pressure is between 25 MPa and 35 MPa, and the temperature is between 40°C and 50°C.

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